UniProt ID | NAB2_YEAST | |
---|---|---|
UniProt AC | P32505 | |
Protein Name | Nuclear polyadenylated RNA-binding protein NAB2 | |
Gene Name | NAB2 | |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
Sequence Length | 525 | |
Subcellular Localization | Nucleus. | |
Protein Description | This essential protein binds to polyadenylated RNA and single-stranded DNA. It may be involved not only in RNA processing but also in transcription regulation. Believed to associate directly with nascent RNA polymerase II transcripts and remain associated during subsequent nuclear RNA processing reactions.. | |
Protein Sequence | MSQEQYTENLKVIVAEKLAGIPNFNEDIKYVAEYIVLLIVNGGTVESVVDELASLFDSVSRDTLANVVQTAFFALEALQQGESAENIVSKIRMMNAQSLGQSDIAQQQQQQQQQQQPDIAQQQPQQQPQQQPQQQPQQQPQQQPQQQPQQQPQQQPQLQPLQPQLGTQNAMQTDAPATPSPISAFSGVVNAAAPPQFAPVDNSQRFTQRGGGAVGKNRRGGRGGNRGGRNNNSTRFNPLAKALGMAGESNMNFTPTKKEGRCRLFPHCPLGRSCPHAHPTKVCNEYPNCPKPPGTCEFLHPNEDEELMKEMERTREEFQKRKADLLAAKRKPVQTGIVLCKFGALCSNPSCPFGHPTPANEDAKVIDLMWCDKNLTCDNPECRKAHSSLSKIKEVKPISQKKAAPPPVEKSLEQCKFGTHCTNKRCKYRHARSHIMCREGANCTRIDCLFGHPINEDCRFGVNCKNIYCLFRHPPGRVLPEKKGAAPNSNVPTNERPFALPENAIIENAPPQTSFTHQEQDTEMN | |
Overview of Protein Modification Sites with Functional and Structural Information | ||
|
* ASA = Accessible Surface Area
Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
---|---|---|---|---|---|
2 | Phosphorylation | ------MSQEQYTEN ------CCHHHHHHH | 42.28 | 22369663 | |
6 | Phosphorylation | --MSQEQYTENLKVI --CCHHHHHHHHHHH | 18.44 | 19823750 | |
7 | Phosphorylation | -MSQEQYTENLKVIV -CCHHHHHHHHHHHH | 20.35 | 19823750 | |
178 | Phosphorylation | MQTDAPATPSPISAF HHCCCCCCCCCHHHH | 24.20 | 28889911 | |
180 | Phosphorylation | TDAPATPSPISAFSG CCCCCCCCCHHHHHC | 30.43 | 28889911 | |
216 | Acetylation | RGGGAVGKNRRGGRG CCCCCCCCCCCCCCC | 40.45 | 25381059 | |
241 | Acetylation | TRFNPLAKALGMAGE CCCHHHHHHHCCCCC | 52.40 | 25381059 | |
249 | Phosphorylation | ALGMAGESNMNFTPT HHCCCCCCCCCCCCC | 40.22 | 24961812 | |
254 | Phosphorylation | GESNMNFTPTKKEGR CCCCCCCCCCCCCCC | 25.66 | 21440633 | |
256 | Phosphorylation | SNMNFTPTKKEGRCR CCCCCCCCCCCCCEE | 52.25 | 28889911 | |
320 | Acetylation | RTREEFQKRKADLLA HHHHHHHHHHHHHHH | 62.27 | 25381059 | |
329 | Acetylation | KADLLAAKRKPVQTG HHHHHHHHCCCCCCC | 56.18 | 25381059 | |
387 | Phosphorylation | PECRKAHSSLSKIKE HHHHHHHHHHHHHCC | 37.52 | 19823750 | |
388 | Phosphorylation | ECRKAHSSLSKIKEV HHHHHHHHHHHHCCC | 27.13 | 19823750 | |
390 | Phosphorylation | RKAHSSLSKIKEVKP HHHHHHHHHHCCCCC | 33.99 | 19823750 | |
401 | Acetylation | EVKPISQKKAAPPPV CCCCCCCCCCCCCCC | 37.27 | 25381059 | |
514 | Phosphorylation | ENAPPQTSFTHQEQD CCCCCCCCCCCCHHC | 23.93 | 30377154 |
Modified Location | Modified Residue | Modification | Function | Reference | ||
---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of NAB2_YEAST !! |
* Distance = the distance between SAP position and PTM sites.
Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of NAB2_YEAST !! |
Kegg Drug | ||||||
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DrugBank | ||||||
There are no disease associations of PTM sites. |
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