dbPTM

PER33_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	PER33_YEAST
UniProt AC	Q12144
Protein Name	Pore and endoplasmic reticulum protein of 33 kDa
Gene Name	PER33
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	273
Subcellular Localization	Endoplasmic reticulum membrane Multi-pass membrane protein. Nucleus, nuclear pore complex.
Protein Description
Protein Sequence	MTVPRNRPMAPFGTIIKSRIKQPQFYWFIGHFLTIFNFIQFHLSITSKQNQLSCYRRSLFYISVTYAIVLYQFFKSDQLKFNFTLLRQEMKKLDNLQYFAMLFILFLLSQFNIIISGSLYSPVIFSIFHFLNYFKENLLPFLPLIPLNLKNLLNSKITVFIQNYNGFFLQMAQVFEIICGLRVGLFLVPFNFFLLLVRRANVSFEVVGTMLAGLTYVWFFKLRYLQSESMRQIFKQYVLRLDAYVSRTLPPYCSRLWNGYKNFVMTVFWKIPV

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
14	Phosphorylation	RPMAPFGTIIKSRIK CCCCCCHHHHHHHCC	21.65	30377154
18	Phosphorylation	PFGTIIKSRIKQPQF CCHHHHHHHCCCCCC	28.91	30377154
235	Acetylation	ESMRQIFKQYVLRLD HHHHHHHHHHHHHHH	42.20	24489116

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of PER33_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of PER33_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of PER33_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PMA1_YEAST	PMA1	genetic	16269340
IZH3_YEAST	IZH3	genetic	16269340
YSY6_YEAST	YSY6	genetic	16269340
IRE1_YEAST	IRE1	genetic	16269340
OSTB_YEAST	WBP1	genetic	16269340
NU133_YEAST	NUP133	genetic	20498018
NU170_YEAST	NUP170	genetic	20498018
UGO1_YEAST	UGO1	genetic	21987634
ISC1_YEAST	ISC1	genetic	21987634
PMA1_YEAST	PMA1	genetic	21987634
CYK2_YEAST	HOF1	genetic	21987634
HSP71_YEAST	SSA1	physical	22940862
LNP_YEAST	LNP1	physical	26041935
SEY1_YEAST	SEY1	physical	26041935
MAK16_YEAST	MAK16	genetic	27708008
CDC24_YEAST	CDC24	genetic	27708008
SEC17_YEAST	SEC17	genetic	27708008
KPC1_YEAST	PKC1	genetic	27708008
CALM_YEAST	CMD1	genetic	27708008
MAK5_YEAST	MAK5	genetic	27708008
CDK1_YEAST	CDC28	genetic	27708008
APC11_YEAST	APC11	genetic	27708008
PRP9_YEAST	PRP9	genetic	27708008
UAP1_YEAST	QRI1	genetic	27708008
NSE4_YEAST	NSE4	genetic	27708008
RRP42_YEAST	RRP42	genetic	27708008
TPIS_YEAST	TPI1	genetic	27708008
DBF4_YEAST	DBF4	genetic	27708008
LCB2_YEAST	LCB2	genetic	27708008
TCPZ_YEAST	CCT6	genetic	27708008
CND3_YEAST	YCG1	genetic	27708008
GDI1_YEAST	GDI1	genetic	27708008
TBP_YEAST	SPT15	genetic	27708008
SEC4_YEAST	SEC4	genetic	27708008
MOB2_YEAST	MOB2	genetic	27708008
ACT_YEAST	ACT1	genetic	27708008
PSB7_YEAST	PRE4	genetic	27708008
SWC4_YEAST	SWC4	genetic	27708008
ESP1_YEAST	ESP1	genetic	27708008
MED6_YEAST	MED6	genetic	27708008
IPI1_YEAST	IPI1	genetic	27708008
CDC12_YEAST	CDC12	genetic	27708008
FDFT_YEAST	ERG9	genetic	27708008
ATC7_YEAST	NEO1	genetic	27708008
MTR4_YEAST	MTR4	genetic	27708008
ARP4_YEAST	ARP4	genetic	27708008
KRE9_YEAST	KRE9	genetic	27708008
DPOD2_YEAST	POL31	genetic	27708008
CDC11_YEAST	CDC11	genetic	27708008
NNF1_YEAST	NNF1	genetic	27708008
YJ9I_YEAST	YJR141W	genetic	27708008
RSC4_YEAST	RSC4	genetic	27708008
RPF2_YEAST	RPF2	genetic	27708008
NMT_YEAST	NMT1	genetic	27708008
NOP56_YEAST	NOP56	genetic	27708008
SEC13_YEAST	SEC13	genetic	27708008
TAD3_YEAST	TAD3	genetic	27708008
NSE5_YEAST	NSE5	genetic	27708008
ORC1_YEAST	ORC1	genetic	27708008
TAF13_YEAST	TAF13	genetic	27708008
SEC59_YEAST	SEC59	genetic	27708008
MED11_YEAST	MED11	genetic	27708008
RRP5_YEAST	RRP5	genetic	27708008
RNT1_YEAST	RNT1	genetic	27708008
DBP6_YEAST	DBP6	genetic	27708008
ESA1_YEAST	ESA1	genetic	27708008
PSA7_YEAST	PRE10	genetic	27708008
TIM50_YEAST	TIM50	genetic	27708008
IPL1_YEAST	IPL1	genetic	27708008
DIM1_YEAST	DIM1	genetic	27708008
IF6_YEAST	TIF6	genetic	27708008
TF2B_YEAST	SUA7	genetic	27708008
BUR1_YEAST	SGV1	genetic	27708008
ERD2_YEAST	ERD2	genetic	27708008
MCM7_YEAST	MCM7	genetic	27708008
CDC48_YEAST	CDC48	genetic	27708008
CDC53_YEAST	CDC53	genetic	27708008
RPB1_YEAST	RPO21	genetic	27708008
NOP14_YEAST	NOP14	genetic	27708008
FAL1_YEAST	FAL1	genetic	27708008
MAK21_YEAST	MAK21	genetic	27708008
CDC1_YEAST	CDC1	genetic	27708008
RIFK_YEAST	FMN1	genetic	27708008
COPB_YEAST	SEC26	genetic	27708008
SMT3_YEAST	SMT3	genetic	27708008
TSC11_YEAST	TSC11	genetic	27708008
YPT1_YEAST	YPT1	genetic	27708008
RPN11_YEAST	RPN11	genetic	27708008
PRS8_YEAST	RPT6	genetic	27708008
DUO1_YEAST	DUO1	genetic	27708008
SP105_YEAST	SPC105	genetic	27708008
PRP18_YEAST	PRP18	genetic	27708008
DAM1_YEAST	DAM1	genetic	27708008
SYMC_YEAST	MES1	genetic	27708008
RRP3_YEAST	RRP3	genetic	27708008
GRP78_YEAST	KAR2	genetic	27708008
HACD_YEAST	PHS1	genetic	27708008
PRP21_YEAST	PRP21	genetic	27708008
HSP77_YEAST	SSC1	genetic	27708008
CDT1_YEAST	TAH11	genetic	27708008
SWD2_YEAST	SWD2	genetic	27708008
CDC16_YEAST	CDC16	genetic	27708008
PRP16_YEAST	PRP16	genetic	27708008
CDC3_YEAST	CDC3	genetic	27708008
RSE1_YEAST	RSE1	genetic	27708008
TEM1_YEAST	TEM1	genetic	27708008
PDS5_YEAST	PDS5	genetic	27708008
UTP15_YEAST	UTP15	genetic	27708008
SPC24_YEAST	SPC24	genetic	27708008
NOP2_YEAST	NOP2	genetic	27708008
TRM6_YEAST	GCD10	genetic	27708008
DPOA_YEAST	POL1	genetic	27708008
SEC12_YEAST	SEC12	genetic	27708008
RRP44_YEAST	DIS3	genetic	27708008
CH10_YEAST	HSP10	genetic	27708008
SGT1_YEAST	SGT1	genetic	27708008
UFE1_YEAST	UFE1	genetic	27708008
RPC1_YEAST	RPO31	genetic	27708008
SMP3_YEAST	SMP3	genetic	27708008
RPB2_YEAST	RPB2	genetic	27708008
MED4_YEAST	MED4	genetic	27708008
DED1_YEAST	DED1	genetic	27708008
GRPE_YEAST	MGE1	genetic	27708008
DYR_YEAST	DFR1	genetic	27708008
APC5_YEAST	APC5	genetic	27708008
SYA_YEAST	ALA1	genetic	27708008
ULP1_YEAST	ULP1	genetic	27708008
GPI2_YEAST	GPI2	genetic	27708008
MOT1_YEAST	MOT1	genetic	27708008
HRR25_YEAST	HRR25	genetic	27708008
NIP7_YEAST	NIP7	genetic	27708008
RDS3_YEAST	RDS3	genetic	27708008
PSB5_YEAST	PRE2	genetic	27708008
PRP4_YEAST	PRP4	genetic	27708008
IMB4_YEAST	KAP123	physical	25413348
SDC1_YEAST	SDC1	physical	25413348
SKP1_YEAST	SKP1	physical	25413348
PDI_YEAST	PDI1	physical	25413348
ETR1_YEAST	ETR1	physical	25413348
MED8_YEAST	MED8	physical	25413348
RUXE_YEAST	SME1	physical	25413348
RBG1_YEAST	RBG1	physical	25413348
RS29A_YEAST	RPS29A	physical	25413348
MED4_YEAST	MED4	physical	25413348
FAT2_YEAST	PCS60	physical	25413348
ELO2_YEAST	ELO2	physical	25413348

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of PER33_YEAST

Related Literatures of Post-Translational Modification