| UniProt ID | LNP_YEAST | |
|---|---|---|
| UniProt AC | P38878 | |
| Protein Name | Endoplasmic reticulum junction formation protein lunapark {ECO:0000305} | |
| Gene Name | LNP1 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 278 | |
| Subcellular Localization |
Endoplasmic reticulum membrane Multi-pass membrane protein . Localizes to three-way ER tubule junctions. This localization is SEY1-dependent. |
|
| Protein Description | Plays a role in tubular endoplasmic reticulum network formation and maintenance. Works in conjunction with the ER shaping proteins (reticulons RTN1 and RTN2, YOP1), and in antagonism to SEY1 to maintain the network in a dynamic equilibrium. May counterbalance SEY1-directed polygon formation by promoting polygon loss through ring closure.. | |
| Protein Sequence | MFSALGKWVRGSRNDKDFVTKYTADLSQITSQIHQLDVALKKSQSILSQWQSNLTFYGIALTVLALSYTYWEYHGYRPYLVVTALLCIGSLILFKWALTKLYAFYNNNRLRKLAKLRAIHQKKLEKLKEETHYNATSSIIQRFSSGEDQNDDAMVLLDDELNAKYQELNNLKTELEKFKKESHVKGLKKEDSDAWFDKIISVLAGGNELDSTSSLSPFKKIICPQCHWKSNCYRLASKPIIFICPHCNHKIDEVKEREDAIEAKQPAQPSQSEKEKTK | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 128 | Acetylation | QKKLEKLKEETHYNA HHHHHHHHHHHCCCH | 24489116 | ||
| 144 | Phosphorylation | SSIIQRFSSGEDQND HHHHHHHCCCCCCCC | 30377154 | ||
| 145 | Phosphorylation | SIIQRFSSGEDQNDD HHHHHHCCCCCCCCC | 19779198 | ||
| 172 | Acetylation | YQELNNLKTELEKFK HHHHHHHHHHHHHHH | 24489116 | ||
| 192 | Phosphorylation | KGLKKEDSDAWFDKI CCCCHHCCHHHHHHH | 30377154 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of LNP_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of LNP_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of LNP_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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