MDM1_YEAST - dbPTM
MDM1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID MDM1_YEAST
UniProt AC Q01846
Protein Name Structural protein MDM1
Gene Name MDM1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 1127
Subcellular Localization Cytoplasm .
Protein Description Essential for mitotic growth. Mediates organelle inheritance..
Protein Sequence MPKFPQFRLILVLFYLISMIQWSVITFSLGFFLNVCIFAYFVFFKSLPDLPKPQPRFVDIVPESSNTVDVDKELKSVEGLIQDGNAQIGKELESIVNLIIKDFVQPWFTKIDKNSDAEFLKVIKWRLLQTLLVVKDKLMKNDSASLIVLKLLPIFNKHFSTFCDAREAVLSDLTLERHKSANIDLQIAVEFNKNYKIHKSLSLKPNALQKEIEKSIRKTVIGLLPHLFDNDELDSLLVFTLMTEVLTTCIISPLIFKFTDPDSWNLRIVSLSQNYFEEKHKVHKIRRMLSKELQDHRKVMNDVANKDVGEPSSEKLELNAEYTGKQFEHYLNQLDSLLDLSDIKYVAYSLALKIYQLKENEHLTKENLKYKKRLLLSLNLIESKLSFPGSEIDTASKKLAREANYPDLNMDNGIVLKEMASFLTSITLKDIVDDSEFLPFFESFLGSVPETQGSTFLEYSQTIESFKNPLEDATSEDIISGYSGISTMQLQEISSKFFHNNNLQNMKLLDEGLVKNIILFRNSFQINNDEDTFILARKSVLLLQTEAIKYLDDRFLPLFKKTPSFLKMLSTSHIISTDIYAHFLSRIGGVNNPEQNKIIKDNVKTDFMNPVRIFANPGITDALDNIVNGSGSKPHKSRISSNPRYSQLFGSENDNIFKDKLFDDENDNTSEISVVEDQLDHPRNMEKVSVSSGNSGLNPSQFYGSNNFRDNIASLTISIDQIEKELELLRHLILKADLTNNQMQLKILKKSQRTLLKELEMKELLKQQYMVQENGNSLFRKTKIYIRSYFSENSSNGLKEITYYIINIHHFNNGQVSSWDMARRYNEFFELNTYLKKNFRDLMRQLQDLFPSKVKMSLKYHVTKTLLYEERKQKLEKYLRELLSISEICEDNIFRRFLTDPTPFKLNKEYMHDDILEEPLHEPIGSSNSTSNSSSVVDLQSSEDGGELNFYEDERHFFTDSGYPFYSQNKSFVKQICDLFISLFALNKANAGWLRGRAIITVLQQLLGSTIEKYIKVSIQKLRSEDQVFEAIVTFKNMLWGDNGLFERKRNETAEATRSEGERLRTEQLALTSLQRLFADTCGRVVGLRDSHEAAGRVHAMLQNPYLNASLLLEALDAILLDIICND
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
396PhosphorylationGSEIDTASKKLAREA
CCHHCHHHHHHHHHC		32.2021440633
641PhosphorylationPHKSRISSNPRYSQL
CCHHCCCCCHHHHHH		48.7821440633
669PhosphorylationFDDENDNTSEISVVE
CCCCCCCCCCEEEEE		30.5121551504
670PhosphorylationDDENDNTSEISVVED
CCCCCCCCCEEEEEH		38.9121440633
673PhosphorylationNDNTSEISVVEDQLD
CCCCCCEEEEEHHCC		18.9621440633
689PhosphorylationPRNMEKVSVSSGNSG
CCCCCEEECCCCCCC		27.6123749301
691PhosphorylationNMEKVSVSSGNSGLN
CCCEEECCCCCCCCC		25.6423749301
692PhosphorylationMEKVSVSSGNSGLNP
CCEEECCCCCCCCCH		39.5828889911
695PhosphorylationVSVSSGNSGLNPSQF
EECCCCCCCCCHHHC		48.4619779198
833PhosphorylationNEFFELNTYLKKNFR
HHHHHHHHHHHHHHH		42.7428889911
1066PhosphorylationSEGERLRTEQLALTS
HHHHHHHHHHHHHHH		32.4519779198
1073PhosphorylationTEQLALTSLQRLFAD
HHHHHHHHHHHHHHH		24.2919779198
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of MDM1_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of MDM1_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of MDM1_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
BUL1_YEASTBUL1genetic
10366593
RSP5_YEASTRSP5genetic
10366593
HSP72_YEASTSSA2physical
22940862
HSP71_YEASTSSA1physical
22940862
RMRP_YEASTSNM1genetic
27708008
SAM35_YEASTSAM35genetic
27708008
HIR1_YEASTHIR1genetic
27708008
YG1X_YEASTYGR050Cgenetic
27708008
PET8_YEASTPET8genetic
27708008
CALM_YEASTCMD1genetic
27708008
TRS20_YEASTTRS20genetic
27708008
MOB2_YEASTMOB2genetic
27708008
NUP57_YEASTNUP57genetic
27708008
SDA1_YEASTSDA1genetic
27708008
SYMC_YEASTMES1genetic
27708008
ORC6_YEASTORC6genetic
27708008
CDC23_YEASTCDC23genetic
27708008
TIM44_YEASTTIM44genetic
27708008
NU159_YEASTNUP159genetic
27708008
ESS1_YEASTESS1genetic
27708008
NOC3_YEASTNOC3genetic
27708008
SEN1_YEASTSEN1genetic
27708008
LIP1_YEASTLIP1genetic
27708008
SRP54_YEASTSRP54genetic
27708008
MED10_YEASTNUT2genetic
27708008
NTH1_YEASTNTG1genetic
27708008
LTE1_YEASTLTE1genetic
27708008
IML3_YEASTIML3genetic
27708008
PP2C4_YEASTPTC4genetic
27708008
ADH5_YEASTADH5genetic
27708008
TRS85_YEASTTRS85genetic
27708008
STP1_YEASTSTP1genetic
27708008
AIM11_YEASTAIM11genetic
27708008
RAD4_YEASTRAD4genetic
27708008
FAB1_YEASTFAB1genetic
27708008
GET1_YEASTGET1genetic
27708008
TFS2_YEASTDST1genetic
27708008
ADH4_YEASTADH4genetic
27708008
AIM18_YEASTAIM18genetic
27708008
ATG32_YEASTATG32genetic
27708008
DAL81_YEASTDAL81genetic
27708008
YJY1_YEASTYJR011Cgenetic
27708008
VPS24_YEASTVPS24genetic
27708008
ELF1_YEASTELF1genetic
27708008
SAC1_YEASTSAC1genetic
27708008
GAP1_YEASTGAP1genetic
27708008
VPS13_YEASTVPS13genetic
27708008
SEI1_YEASTFLD1genetic
27708008
YL456_YEASTYLR456Wgenetic
27708008
MRE11_YEASTMRE11genetic
27708008
YM71_YEASTYMR226Cgenetic
27708008
KC12_YEASTYCK2genetic
27708008
DIA2_YEASTDIA2genetic
27708008
WHI5_YEASTWHI5genetic
27708008
KIN4_YEASTKIN4genetic
27708008
PMT3_YEASTPMT3genetic
27708008
HAT1_YEASTHAT1genetic
27708008
SRO7_YEASTSRO7genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of MDM1_YEAST

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Related Literatures of Post-Translational Modification

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