dbPTM

The statistics of PTM sites in dbPTM

The dbPTM has been maintained for over ten years with an attempt to provide comprehensively functional and structural analyses for post-translational modifications (PTMs). In this update, dbPTM not only integrate more experimentally validated PTMs from available databases and manual curation of literature, but also provide disease association based on non-synonymous single nucleotide polymorphisms (nsSNPs). The high-throughput deep sequencing technology has leaded the analysis of association between SNPs and diseases into a data surge in both growth and scope. This update thus integrated disease-associated nsSNPs from dbSNP based on Genome-Wide Association Studies (GWAS). The PTM substrate sites locating in a specified distance of the amino acids encoded from nsSNPs were referred to having an association with its involving diseases.

The statistics of experimental and putative PTM sites in dbPTM

PTM Type	Number of experimental sites	Number of putative sites	Total number of PTM sites	Number of literatures
Acetylation	138,171	38,530	176,701	19,451
ADP-ribosylation	107	670	777	35
Amidation	3,316	1,462	4,778	1,084
AMPylation	27	65	92	20
Biotinylation	12	83	95	12
Blocked amino end	26	73	99	25
Butyrylation	82	269	351	3
Carbamidation	22	0	22	1
Carboxyethylation	1	5	6	1
Carboxylation	44	1,513	1,557	63
Cholesterol ester	2	28	30	2
Cholesterylation	2	0	2	1
Citrullination	122	711	833	18
C-linked_Glycosylation	232	149	381	19
Crotonylation	373	286	659	7
Deamidation	92	382	474	44
Deamination	42	150	192	13
Decanoylation	6	1	7	7
Decarboxylation	2	2	4	2
Dephosphorylation	133	0	133	95
D-glucuronoylation	1	0	1	1
Disulfide bond	6	0	6	1
Farnesylation	164	355	519	83
Formation of an isopeptide bond	29	228	257	16
Formylation	256	51	307	47
Gamma-carboxyglutamic_acid	896	729	1,625	96
Geranylgeranylation	157	1,051	1,208	50
Glutarylation	952	704	1,656	4
Glutathionylation	4,129	44	4,173	85
Glycation	0	323	323	0
GPI-anchor	103	1,021	1,124	57
Hydroxyceramide ester	3	1	4	1
Hydroxylation	2,404	4,543	6,947	353
Iodination	19	70	89	2
Lactoylation	306	587	893	1
Lactylation	336	0	336	2
Lipoylation	35	618	653	30
Malonylation	12,847	145	12,992	12
Methylation	16,114	16,766	32,880	8,897
Myristoylation	312	1,460	1,772	207
N-carbamoylation	1	0	1	1
Neddylation	1,676	48	1,724	4
Nitration	130	1,610	1,740	17
N-linked_Glycosylation	28,412	89,211	117,623	1,951
N-palmitoylation	74	2,189	2,263	64
Octanoylation	13	6	19	8
O-linked_Glycosylation	22,173	3,642	25,815	4,438
O-palmitoleoylation	6	188	194	11
O-palmitoylation	3	11	14	3
Other	1,257	9,484	10,741	343
Oxidation	427	774	1,201	83
Phosphatidylethanolamine amidation	9	83	92	7
Phosphoglycerylation	0	141	141	0
Phosphorylation	1,615,150	160,490	1,775,640	39,780
Propionylation	13	159	172	3
Pupylation	0	215	215	0
Pyrrolidone_carboxylic_acid	1,846	1,838	3,684	571
Pyrrolylation	1	471	472	1
Pyruvate	25	1,739	1,764	21
S-archaeol	1	11	12	1
S-carbamoylation	1	5	6	2
S-Cyanation	1	5	6	2
S-cysteinylation	2	13	15	2
S-diacylglycerol	58	2,137	2,195	50
Serotonylation	9	44	53	2
S-linked_Glycosylation	5	6	11	7
S-nitrosylation	4,172	483	4,655	190
S-palmitoylation	6,505	3,423	9,928	572
S-selanylation	0	4	4	0
Stearoylation	3	10	13	3
Succinylation	17,973	11,868	29,841	59
Sulfation	252	1,628	1,880	129
Sulfhydration	8	169	177	7
Sulfoxidation	7,581	0	7,581	124
Sumoylation	5,889	5,731	11,620	221
Thiocarboxylation	13	82	95	13
Ubiquitination	348,308	108,349	456,657	670
UMPylation	10	37	47	8
2-Hydroxyisobutyrylation	0	32,392	32,392	0
Others	0	34,780	34,780	0
Total in dbPTM	2,243,890	546,551	2,790,441	80,216

The statistics of kinase-substrates

Select Cancer Type:

Kinase	Number of substrates	Cancer Type	Number of Substrates Expression in Tumor Group	Number of Substrates Expression in Normal Group
MAPK1	3,653	CRC	1,029	824
PRKCB	3,645	CRC	381	204
CDK1	3,527	CRC	632	473
SRC	3,418	CRC	65	20
PRKCA	3,390	CRC	306	188
MAPK3	3,253	CRC	853	654
CSNK2A1	3,097	CRC	669	464
PLK1	2,941	CRC	541	392
ABL1	2,437	CRC	126	91
GSK3B	2,369	CRC	408	257
PRKACA	2,337	CRC	436	370
YES1	2,161	CRC	169	0
NEK2	2,152	CRC	237	118
AKT1	2,097	CRC	419	322
TTK	2,048	CRC	419	265
AURKA	2,034	CRC	227	148
CDK2	1,999	CRC	399	307
MAPK14	1,975	CRC	688	563
EPHA3	1,851	CRC	32	0
FYN	1,850	CRC	47	0
IKBKB	1,714	CRC	253	160
INSR	1,712	CRC	43	0
FES	1,708	CRC	28	0
CSNK1D	1,630	CRC	278	178
MAPK8	1,611	CRC	363	278
FLT3	1,584	CRC	21	0
EPHB1	1,576	CRC	29	0
EPHB3	1,478	CRC	22	0
GRK2	1,475	CRC	207	124
RET	1,469	CRC	35	14
AURKB	1,431	CRC	189	128
GSK3A	1,417	CRC	355	217
MAP2K1	1,377	CRC	277	195
FER	1,376	CRC	27	0
PRKCI	1,367	CRC	511	373
EGFR	1,328	CRC	41	0
CSNK1E	1,321	CRC	395	295
MAP4K5	1,313	CRC	444	348
RPS6KA1	1,286	CRC	303	197
EPHA2	1,273	CRC	26	0
CHUK	1,230	CRC	219	140
PRKDC	1,218	CRC	133	78
ATM	1,214	CRC	71	36
SRMS	1,203	CRC	30	0
ERBB4	1,191	CRC	33	0
BTK	1,160	CRC	41	24
PAK1	1,151	CRC	264	198
FGFR1	1,142	CRC	29	0
CSNK1A1	1,138	CRC	215	121
RAF1	1,128	CRC	249	141
ROCK1	1,096	CRC	248	178
PRKCG	1,094	CRC	187	111
FGFR2	1,088	CRC	32	0
ERN1	1,081	CRC	535	416
CSNK2A2	1,074	CRC	393	267
PRKCD	1,069	CRC	135	83
MAP3K1	1,063	CRC	328	248
PRKCE	1,061	CRC	144	93
CAMK2A	1,045	CRC	185	131
MAP4K4	1,038	CRC	238	168
JAK3	1,035	CRC	14	14
HIPK2	1,008	CRC	226	167
PAK3	987	CRC	247	173
MINK1	972	CRC	201	159
KDR	968	CRC	29	0
PAK2	926	CRC	206	145
MAPK7	923	CRC	203	136
IRAK1	919	CRC	339	261
EPHA6	913	CRC	18	0
JAK2	907	CRC	17	0
MAPK13	897	CRC	286	218
MAPK12	894	CRC	283	227
CIT	892	CRC	467	375
CDK5	882	CRC	204	166
CHEK1	858	CRC	101	68
STK4	845	CRC	101	66
CAMKK2	829	CRC	385	305
CDK7	811	CRC	176	94
CAMK2D	804	CRC	203	145
ROCK2	800	CRC	175	120
MAPK9	794	CRC	217	173
STK3	785	CRC	88	50
MAPK11	779	CRC	176	142
MAP2K4	774	CRC	114	77
NEK1	773	CRC	97	38
RPS6KA2	754	CRC	351	277
MARK4	750	CRC	138	102
MAP3K9	747	CRC	62	29
CAMK2G	731	CRC	181	133
PDK1	724	CRC	145	92
STK24	718	CRC	54	27
PRKCZ	717	CRC	83	56
AKT2	712	CRC	204	158
NEK6	707	CRC	63	27
DYRK2	701	CRC	181	136
TTBK1	701	CRC	87	52
IKBKE	699	CRC	104	57
ZAP70	699	CRC	29	0
PRKG2	696	CRC	157	118
CLK1	693	CRC	247	185
TAOK3	692	CRC	367	291
SRPK1	685	CRC	345	292
PRKG1	681	CRC	143	97
CAMK2B	676	CRC	131	91
PIM1	676	CRC	89	59
STK26	674	CRC	61	36
CDK4	670	CRC	113	70
PRKD1	658	CRC	119	83
RPS6KB1	656	CRC	152	109
PRKACB	653	CRC	157	124
NEK7	636	CRC	57	27
NEK4	618	CRC	48	21
MAPK10	609	CRC	150	116
STK25	604	CRC	43	17
TNIK	604	CRC	36	16
SIK2	595	CRC	104	74
PRKAA2	571	CRC	132	75
AURKC	570	CRC	79	53
MAP2K6	569	CRC	88	64
PLK3	555	CRC	94	57
MAPKAPK3	552	CRC	134	97
PRKAA1	530	CRC	81	60
NLK	527	CRC	107	70
TAOK2	521	CRC	46	25
MAP2K2	516	CRC	99	73
RPS6KA3	516	CRC	134	105
CDK9	507	CRC	219	161
PHKG2	506	CRC	100	64
MAP3K11	505	CRC	57	32
NIM1K	503	CRC	66	48
PRKCH	502	CRC	101	57
MARK1	498	CRC	77	61
SGK1	496	CRC	112	81
TBK1	495	CRC	75	38
NEK9	494	CRC	56	28
MAPKAPK2	492	CRC	149	130
RPS6KA5	480	CRC	136	102
MAP3K10	479	CRC	40	20
TGFBR2	465	CRC	91	55
PLK4	462	CRC	43	26
DAPK1	458	CRC	77	40
ATR	456	CRC	21	12
MAP4K2	455	CRC	32	14
MAP3K20	450	CRC	44	22
MAP2K7	447	CRC	52	52
PIM3	445	CRC	60	40
CDK6	444	CRC	128	85
MARK2	442	CRC	89	64
MAPKAPK5	441	CRC	115	84
MAP3K7	439	CRC	40	28
MAP2K3	437	CRC	70	49
STK11	430	CRC	47	14
MARK3	427	CRC	95	80
TLK1	418	CRC	60	27
CAMK4	417	CRC	100	67
SGK3	417	CRC	88	65
GRK5	413	CRC	81	55
EIF2AK2	399	CRC	85	53
MATK	396	CRC	63	51
DYRK3	392	CRC	110	85
IRAK4	391	CRC	39	12
TSSK1B	381	CRC	75	57
MTOR	374	CRC	87	66
DCLK2	373	CRC	54	37
ACVR1B	366	CRC	65	37
SIK1	364	CRC	112	86
CSNK1G2	363	CRC	73	43
PRKACG	360	CRC	87	69
AKT3	347	CRC	114	81
TLK2	343	CRC	42	22
MKNK2	341	CRC	70	48
CSNK1G1	327	CRC	62	36
PRKD3	319	CRC	60	43
PAK4	314	CRC	105	75
RPS6KA6	312	CRC	85	61
TAOK1	309	CRC	46	23
PTK2	305	CRC	22	17
MAP2K5	304	CRC	59	28
SRPK3	295	CRC	180	150
TSSK2	294	CRC	64	46
BMPR1B	289	CRC	43	24
LATS1	288	CRC	107	84
DYRK4	279	CRC	120	100
DSTYK	277	CRC	36	19
LATS2	277	CRC	69	43
ULK3	272	CRC	46	24
NEK11	269	CRC	27	14
GRK7	267	CRC	61	36
BUB1B	261	CRC	57	33
DYRK1A	256	CRC	98	85
TGFBR1	253	CRC	44	28
WNK3	244	CRC	37	23
CHEK2	243	CRC	31	24
PKN1	243	CRC	47	32
CAMKK1	239	CRC	19	10
CAMK1	228	CRC	52	38
ACVR1	225	CRC	48	29
RPS6KA4	221	CRC	77	62
PBK	214	CRC	19	10
CILK1	210	CRC	63	41
PAK6	209	CRC	35	26
WNK1	209	CRC	28	16
CSNK1G3	206	CRC	40	23
PRKD2	206	CRC	50	37
NUAK2	205	CRC	52	33
FAM20C	204	CRC	64	40
DMPK	201	CRC	42	32
ACVR2A	200	CRC	49	33
MYLK2	191	CRC	40	25
GRK1	189	CRC	40	26
GRK3	187	CRC	12	6
MOK	187	CRC	40	31
ULK1	187	CRC	28	21
WNK2	186	CRC	18	18
CAMK1D	174	CRC	47	38
PAK5	173	CRC	43	32
MELK	173	CRC	39	39
SLK	171	CRC	20	11
PRKX	169	CRC	62	49
DCLK1	163	CRC	26	16
RPS6KB2	161	CRC	38	29
PLK2	157	CRC	17	8
CLK2	155	CRC	46	35
MAP3K8	153	CRC	27	14
HIPK1	150	CRC	49	39
OXSR1	149	CRC	18	10
PIM2	147	CRC	33	19
GRK4	142	CRC	15	5
SGK2	142	CRC	48	36
NUAK1	141	CRC	26	19
CDC42BPB	138	CRC	40	23
EEF2K	136	CRC	18	8
MAP3K2	132	CRC	40	31
CDC42BPA	130	CRC	40	21
HASPIN	130	CRC	9	3
STK38L	128	CRC	29	20
GRK6	121	CRC	9	6
PDK4	121	CRC	22	16
STK38	120	CRC	27	18
EIF2AK3	117	CRC	17	6
MOS	117	CRC	18	8
PDPK1	109	CRC	22	20
DAPK3	107	CRC	18	10
LRRK2	107	CRC	23	18
MAP3K3	106	CRC	39	31
PHKG1	104	CRC	26	16
STK39	104	CRC	15	9
CLK3	103	CRC	50	38
EIF2AK1	102	CRC	45	35
HIPK4	101	CRC	35	27
MAPK15	101	CRC	25	20
PKN2	99	CRC	28	23
ACVR2B	97	CRC	19	15
MAP3K5	97	CRC	8	5
CDK3	96	CRC	13	10
BRSK2	95	CRC	26	21
CDC7	93	CRC	16	9
HIPK3	91	CRC	49	42
STK16	89	CRC	17	9
TRPM6	72	CRC	5	2
BUB1	70	CRC	7	6
CLK4	70	CRC	9	8
VRK1	68	CRC	8	5
STK10	60	CRC	8	6
BRSK1	59	CRC	14	8
DYRK1B	58	CRC	14	11
PASK	58	CRC	13	9
NEK3	57	CRC	2	1
BMPR2	55	CRC	15	7
STK33	54	CRC	21	18
BMPR1A	53	CRC	15	10
CDKL5	52	CRC	17	14
MAK	50	CRC	26	17
VRK2	50	CRC	2	2
RIPK2	47	CRC	5	3
BRAF	46	CRC	11	8
MAP3K14	45	CRC	4	3
SRPK2	42	CRC	18	16
CDK8	39	CRC	1	1
MYLK	38	CRC	11	10
CSNK1A1L	37	CRC	8	5
MAP3K15	37	CRC	22	17
PNCK	37	CRC	11	7
BCKDK	36	CRC	11	5
DAPK2	36	CRC	9	4
EIF2AK4	35	CRC	11	6
MKNK1	34	CRC	4	3
WNK4	34	CRC	7	5
CDK12	29	CRC	13	3
UHMK1	25	CRC	5	5
MAST2	24	CRC	7	7
MAP3K12	22	CRC	7	5
CDK14	21	CRC	4	4
CDK17	20	CRC	13	10
CDK16	19	CRC	6	5
ULK2	19	CRC	2	2
RIPK3	15	CRC	5	5
MAP4K1	14	CRC	1	1
CDK19	13	CRC	1	1
CAMK1G	12	CRC	1	0
MAP3K6	10	CRC	2	2
PKN3	10	CRC	5	5
BMP2K	9	CRC	6	6
AAK1	8	CRC	1	1
CDK18	7	CRC	3	2
STK17A	5	CRC	2	2
MASTL	4	CRC	1	1
MAPK1	3,653	GBM	1,089	1,089
PRKCB	3,645	GBM	332	332
CDK1	3,527	GBM	753	753
SRC	3,418	GBM	44	44
PRKCA	3,390	GBM	244	244
MAPK3	3,253	GBM	880	880
CSNK2A1	3,097	GBM	572	572
PLK1	2,941	GBM	546	546
ABL1	2,437	GBM	125	125
GSK3B	2,369	GBM	402	402
PRKACA	2,337	GBM	446	446
NEK2	2,152	GBM	229	229
AKT1	2,097	GBM	404	404
TTK	2,048	GBM	370	370
AURKA	2,034	GBM	250	250
CDK2	1,999	GBM	425	425
MAPK14	1,975	GBM	597	597
IKBKB	1,714	GBM	255	255
FES	1,708	GBM	17	17
NTRK3	1,677	GBM	25	25
FGR	1,647	GBM	39	39
CSNK1D	1,630	GBM	292	292
MAPK8	1,611	GBM	387	387
FLT3	1,584	GBM	24	24
NTRK1	1,509	GBM	36	36
GRK2	1,475	GBM	181	181
RET	1,469	GBM	24	24
AURKB	1,431	GBM	169	169
GSK3A	1,417	GBM	344	344
MAP2K1	1,377	GBM	259	259
FER	1,376	GBM	13	13
PRKCI	1,367	GBM	449	449
EGFR	1,328	GBM	37	37
CSNK1E	1,321	GBM	367	367
MAP4K5	1,313	GBM	392	392
RPS6KA1	1,286	GBM	278	278
CHUK	1,230	GBM	202	202
PRKDC	1,218	GBM	181	181
ATM	1,214	GBM	78	78
BTK	1,160	GBM	42	42
PAK1	1,151	GBM	266	266
CSNK1A1	1,138	GBM	170	170
RAF1	1,128	GBM	225	225
ROCK1	1,096	GBM	235	235
PRKCG	1,094	GBM	141	141
ERN1	1,081	GBM	510	510
CSNK2A2	1,074	GBM	308	308
PRKCD	1,069	GBM	113	113
MAP3K1	1,063	GBM	299	299
PRKCE	1,061	GBM	110	110
CAMK2A	1,045	GBM	208	208
MAP4K4	1,038	GBM	182	182
HIPK2	1,008	GBM	201	201
PAK3	987	GBM	247	247
MINK1	972	GBM	189	189
PAK2	926	GBM	215	215
MAPK7	923	GBM	152	152
PRKCQ	921	GBM	89	89
IRAK1	919	GBM	305	305
JAK2	907	GBM	17	17
MAPK13	897	GBM	273	273
MAPK12	894	GBM	270	270
CIT	892	GBM	432	432
CDK5	882	GBM	303	303
CHEK1	858	GBM	87	87
STK4	845	GBM	79	79
CAMKK2	829	GBM	348	348
CDK7	811	GBM	148	148
CAMK2D	804	GBM	211	211
ROCK2	800	GBM	147	147
MAPK9	794	GBM	184	184
STK3	785	GBM	64	64
MAPK11	779	GBM	194	194
MAP2K4	774	GBM	123	123
NEK1	773	GBM	77	77
RPS6KA2	754	GBM	287	287
MARK4	750	GBM	184	184
MAP3K9	747	GBM	47	47
CAMK2G	731	GBM	184	184
PDK1	724	GBM	142	142
STK24	718	GBM	35	35
PRKCZ	717	GBM	71	71
AKT2	712	GBM	195	195
NEK6	707	GBM	38	38
DYRK2	701	GBM	164	164
TTBK1	701	GBM	70	70
IKBKE	699	GBM	74	74
PRKG2	696	GBM	160	160
CLK1	693	GBM	237	237
TAOK3	692	GBM	342	342
SRPK1	685	GBM	318	318
PRKG1	681	GBM	116	116
CAMK2B	676	GBM	163	163
PIM1	676	GBM	79	79
STK26	674	GBM	37	37
CDK4	670	GBM	110	110
PRKD1	658	GBM	120	120
RPS6KB1	656	GBM	148	148
PRKACB	653	GBM	150	150
NEK7	636	GBM	47	47
NEK4	618	GBM	29	29
MAPK10	609	GBM	149	149
STK25	604	GBM	20	20
TNIK	604	GBM	23	23
SIK2	595	GBM	95	95
LIMK1	592	GBM	96	96
PRKAA2	571	GBM	126	126
AURKC	570	GBM	71	71
MAP2K6	569	GBM	92	92
PLK3	555	GBM	59	59
MAPKAPK3	552	GBM	135	135
PRKAA1	530	GBM	74	74
NLK	527	GBM	80	80
TAOK2	521	GBM	15	15
MAP2K2	516	GBM	80	80
RPS6KA3	516	GBM	109	109
CDK9	507	GBM	189	189
PHKG2	506	GBM	66	66
MAP3K11	505	GBM	32	32
NIM1K	503	GBM	76	76
PRKCH	502	GBM	47	47
MARK1	498	GBM	139	139
SGK1	496	GBM	103	103
TBK1	495	GBM	39	39
NEK9	494	GBM	41	41
MAPKAPK2	492	GBM	149	149
RPS6KA5	480	GBM	125	125
MAP3K10	479	GBM	29	29
TGFBR2	465	GBM	74	74
PLK4	462	GBM	40	40
DAPK1	458	GBM	65	65
ATR	456	GBM	35	35
MAP4K2	455	GBM	19	19
MAP3K20	450	GBM	24	24
MAP2K7	447	GBM	75	75
PIM3	445	GBM	49	49
CDK6	444	GBM	107	107
MARK2	442	GBM	97	97
MAPKAPK5	441	GBM	113	113
MAP3K7	439	GBM	22	22
MAP2K3	437	GBM	69	69
STK11	430	GBM	33	33
MARK3	427	GBM	103	103
TLK1	418	GBM	43	43
CAMK4	417	GBM	102	102
SGK3	417	GBM	81	81
GRK5	413	GBM	64	64
EIF2AK2	399	GBM	72	72
MATK	396	GBM	50	50
DYRK3	392	GBM	93	93
IRAK4	391	GBM	16	16
TSSK1B	381	GBM	72	72
MTOR	374	GBM	84	84
DCLK2	373	GBM	45	45
ACVR1B	366	GBM	46	46
SIK1	364	GBM	106	106
CSNK1G2	363	GBM	59	59
PRKACG	360	GBM	67	67
AKT3	347	GBM	101	101
TLK2	343	GBM	35	35
MKNK2	341	GBM	64	64
CSNK1G1	327	GBM	48	48
PRKD3	319	GBM	63	63
PAK4	314	GBM	78	78
RPS6KA6	312	GBM	70	70
TAOK1	309	GBM	27	27
MAP2K5	304	GBM	40	40
SRPK3	295	GBM	148	148
TSSK2	294	GBM	57	57
BMPR1B	289	GBM	31	31
LATS1	288	GBM	89	89
DYRK4	279	GBM	103	103
DSTYK	277	GBM	29	29
LATS2	277	GBM	46	46
ULK3	272	GBM	28	28
NEK11	269	GBM	10	10
GRK7	267	GBM	46	46
BUB1B	261	GBM	33	33
DYRK1A	256	GBM	94	94
TGFBR1	253	GBM	34	34
WNK3	244	GBM	22	22
CHEK2	243	GBM	25	25
PKN1	243	GBM	35	35
CAMKK1	239	GBM	7	7
CAMK1	228	GBM	69	69
ACVR1	225	GBM	35	35
RPS6KA4	221	GBM	64	64
PBK	214	GBM	10	10
CILK1	210	GBM	53	53
PAK6	209	GBM	31	31
WNK1	209	GBM	19	19
CSNK1G3	206	GBM	26	26
PRKD2	206	GBM	50	50
NUAK2	205	GBM	42	42
FAM20C	204	GBM	60	60
DMPK	201	GBM	48	48
ACVR2A	200	GBM	33	33
MYLK2	191	GBM	37	37
GRK1	189	GBM	30	30
GRK3	187	GBM	16	16
MOK	187	GBM	39	39
ULK1	187	GBM	32	32
CAMK1D	174	GBM	46	46
PAK5	173	GBM	36	36
MELK	173	GBM	48	48
SLK	171	GBM	8	8
PRKX	169	GBM	58	58
DCLK1	163	GBM	19	19
RPS6KB2	161	GBM	40	40
PLK2	157	GBM	14	14
CLK2	155	GBM	45	45
MAP3K8	153	GBM	8	8
HIPK1	150	GBM	31	31
OXSR1	149	GBM	4	4
PIM2	147	GBM	23	23
GRK4	142	GBM	11	11
SGK2	142	GBM	46	46
NUAK1	141	GBM	23	23
CDC42BPB	138	GBM	26	26
EEF2K	136	GBM	8	8
MAP3K2	132	GBM	31	31
CDC42BPA	130	GBM	23	23
HASPIN	130	GBM	4	4
STK38L	128	GBM	23	23
GRK6	121	GBM	14	14
PDK4	121	GBM	17	17
STK38	120	GBM	20	20
EIF2AK3	117	GBM	11	11
MOS	117	GBM	7	7
PDPK1	109	GBM	8	8
DAPK3	107	GBM	10	10
LRRK2	107	GBM	19	19
MAP3K3	106	GBM	22	22
PHKG1	104	GBM	11	11
STK39	104	GBM	10	10
CLK3	103	GBM	40	40
EIF2AK1	102	GBM	35	35
HIPK4	101	GBM	40	40
MAPK15	101	GBM	14	14
PKN2	99	GBM	26	26
ACVR2B	97	GBM	25	25
MAP3K5	97	GBM	3	3
CDK3	96	GBM	17	17
BRSK2	95	GBM	21	21
CDC7	93	GBM	9	9
HIPK3	91	GBM	36	36
STK16	89	GBM	10	10
TRPM6	72	GBM	1	1
BUB1	70	GBM	6	6
CLK4	70	GBM	15	15
VRK1	68	GBM	7	7
STK10	60	GBM	3	3
BRSK1	59	GBM	7	7
DYRK1B	58	GBM	13	13
PASK	58	GBM	10	10
NEK3	57	GBM	7	7
BMPR2	55	GBM	4	4
STK33	54	GBM	19	19
BMPR1A	53	GBM	7	7
CDKL5	52	GBM	22	22
MAK	50	GBM	29	29
VRK2	50	GBM	3	3
RIPK2	47	GBM	5	5
BRAF	46	GBM	8	8
MAP3K14	45	GBM	2	2
SRPK2	42	GBM	16	16
CDK8	39	GBM	2	2
MYLK	38	GBM	4	4
CSNK1A1L	37	GBM	6	6
MAP3K15	37	GBM	15	15
PNCK	37	GBM	9	9
BCKDK	36	GBM	11	11
DAPK2	36	GBM	4	4
EIF2AK4	35	GBM	4	4
MKNK1	34	GBM	4	4
WNK4	34	GBM	6	6
PINK1	32	GBM	1	1
CDK12	29	GBM	8	8
UHMK1	25	GBM	5	5
MAP3K12	22	GBM	4	4
CDK14	21	GBM	3	3
CDK17	20	GBM	12	12
CDK16	19	GBM	7	7
TRPM7	19	GBM	1	1
ULK2	19	GBM	1	1
SMG1	16	GBM	1	1
RIPK3	15	GBM	4	4
TTBK2	15	GBM	4	4
MAP4K1	14	GBM	1	1
CDK19	13	GBM	1	1
CAMK1G	12	GBM	2	2
MAP3K6	10	GBM	2	2
PKN3	10	GBM	4	4
BMP2K	9	GBM	4	4
CDK18	7	GBM	2	2
STK17A	5	GBM	2	2
SIK3	3	GBM	2	2
MAPK1	3,653	HCC	955	955
PRKCB	3,645	HCC	513	513
CDK1	3,527	HCC	630	630
SRC	3,418	HCC	54	54
PRKCA	3,390	HCC	392	392
MAPK3	3,253	HCC	796	796
CSNK2A1	3,097	HCC	672	672
PLK1	2,941	HCC	615	615
ABL1	2,437	HCC	149	149
GSK3B	2,369	HCC	392	392
PRKACA	2,337	HCC	528	528
YES1	2,161	HCC	257	257
NEK2	2,152	HCC	303	303
AKT1	2,097	HCC	491	491
TTK	2,048	HCC	348	348
AURKA	2,034	HCC	295	295
CDK2	1,999	HCC	416	416
MAPK14	1,975	HCC	686	686
EPHA3	1,851	HCC	41	41
FYN	1,850	HCC	48	48
PDGFRB	1,723	HCC	339	339
IKBKB	1,714	HCC	380	380
INSR	1,712	HCC	56	56
FES	1,708	HCC	25	25
EPHB2	1,689	HCC	37	37
MET	1,687	HCC	47	47
ARAF	1,686	HCC	809	809
NTRK3	1,677	HCC	54	54
FGR	1,647	HCC	56	56
ALK	1,638	HCC	52	52
CSNK1D	1,630	HCC	319	319
MAPK8	1,611	HCC	400	400
EPHA8	1,600	HCC	35	35
FLT3	1,584	HCC	38	38
EPHB1	1,576	HCC	40	40
NTRK1	1,509	HCC	53	53
EPHB3	1,478	HCC	31	31
GRK2	1,475	HCC	207	207
RET	1,469	HCC	33	33
LCK	1,446	HCC	34	34
AURKB	1,431	HCC	209	209
GSK3A	1,417	HCC	340	340
HCK	1,400	HCC	37	37
EPHB4	1,388	HCC	24	24
MAP2K1	1,377	HCC	247	247
FER	1,376	HCC	21	21
MUSK	1,376	HCC	38	38
PRKCI	1,367	HCC	490	490
BMX	1,364	HCC	34	34
EGFR	1,328	HCC	33	33
BLK	1,325	HCC	35	35
CSNK1E	1,321	HCC	446	446
MAP4K5	1,313	HCC	471	471
RPS6KA1	1,286	HCC	359	359
EPHA2	1,273	HCC	42	42
EPHA5	1,255	HCC	38	38
FLT4	1,247	HCC	44	44
TEC	1,237	HCC	30	30
CHUK	1,230	HCC	288	288
TYRO3	1,230	HCC	20	20
ROS1	1,227	HCC	35	35
MST1R	1,223	HCC	23	23
PRKDC	1,218	HCC	151	151
EPHA1	1,216	HCC	35	35
ATM	1,214	HCC	77	77
SRMS	1,203	HCC	25	25
ERBB4	1,191	HCC	28	28
TNK1	1,175	HCC	21	21
BTK	1,160	HCC	54	54
PAK1	1,151	HCC	318	318
PDGFRA	1,151	HCC	27	27
FGFR1	1,142	HCC	27	27
LTK	1,139	HCC	30	30
CSNK1A1	1,138	HCC	194	194
RAF1	1,128	HCC	259	259
FRK	1,119	HCC	28	28
TEK	1,097	HCC	24	24
ROCK1	1,096	HCC	250	250
PRKCG	1,094	HCC	187	187
KIT	1,094	HCC	141	141
FGFR2	1,088	HCC	23	23
IGF1R	1,085	HCC	36	36
ERN1	1,081	HCC	533	533
CSNK2A2	1,074	HCC	371	371
PRKCD	1,069	HCC	142	142
EPHA7	1,066	HCC	35	35
MAP3K1	1,063	HCC	374	374
PRKCE	1,061	HCC	167	167
ABL2	1,050	HCC	99	99
CAMK2A	1,045	HCC	243	243
MAP4K4	1,038	HCC	259	259
JAK3	1,035	HCC	26	26
HIPK2	1,008	HCC	236	236
TNK2	995	HCC	355	355
INSRR	990	HCC	32	32
PAK3	987	HCC	299	299
PTK6	978	HCC	22	22
MINK1	972	HCC	234	234
KDR	968	HCC	34	34
CSF1R	965	HCC	34	34
NTRK2	940	HCC	30	30
AXL	939	HCC	21	21
ITK	927	HCC	31	31
PAK2	926	HCC	268	268
MAPK7	923	HCC	201	201
PRKCQ	921	HCC	176	176
IRAK1	919	HCC	356	356
MERTK	919	HCC	18	18
EPHA6	913	HCC	34	34
JAK2	907	HCC	27	27
MAPK13	897	HCC	290	290
MAPK12	894	HCC	302	302
CIT	892	HCC	461	461
CDK5	882	HCC	207	207
CHEK1	858	HCC	137	137
STK4	845	HCC	124	124
CAMKK2	829	HCC	378	378
FLT1	823	HCC	29	29
CDK7	811	HCC	189	189
TXK	806	HCC	30	30
CAMK2D	804	HCC	247	247
ROCK2	800	HCC	161	161
MAPK9	794	HCC	219	219
STK3	785	HCC	104	104
MAPK11	779	HCC	189	189
MAP2K4	774	HCC	120	120
NEK1	773	HCC	105	105
EPHA4	766	HCC	25	25
RPS6KA2	754	HCC	380	380
MARK4	750	HCC	237	237
PTK2B	748	HCC	16	16
MAP3K9	747	HCC	100	100
CAMK2G	731	HCC	256	256
PDK1	724	HCC	148	148
STK24	718	HCC	81	81
PRKCZ	717	HCC	132	132
AKT2	712	HCC	254	254
NEK6	707	HCC	110	110
DYRK2	701	HCC	228	228
TTBK1	701	HCC	132	132
IKBKE	699	HCC	152	152
ZAP70	699	HCC	15	15
DDR2	698	HCC	16	16
PRKG2	696	HCC	182	182
CLK1	693	HCC	309	309
TAOK3	692	HCC	358	358
SRPK1	685	HCC	349	349
PRKG1	681	HCC	141	141
CAMK2B	676	HCC	168	168
PIM1	676	HCC	133	133
STK26	674	HCC	89	89
CDK4	670	HCC	119	119
PRKD1	658	HCC	134	134
RPS6KB1	656	HCC	199	199
PRKACB	653	HCC	201	201
ERBB2	644	HCC	18	18
NEK7	636	HCC	123	123
FGFR3	636	HCC	18	18
NEK4	618	HCC	67	67
MAPK10	609	HCC	175	175
STK25	604	HCC	64	64
TNIK	604	HCC	54	54
SIK2	595	HCC	199	199
LIMK1	592	HCC	129	129
PRKAA2	571	HCC	145	145
AURKC	570	HCC	134	134
MAP2K6	569	HCC	92	92
FGFR4	569	HCC	15	15
PLK3	555	HCC	122	122
MAPKAPK3	552	HCC	192	192
PRKAA1	530	HCC	85	85
LYN	530	HCC	12	12
NLK	527	HCC	116	116
TAOK2	521	HCC	64	64
MAP2K2	516	HCC	98	98
RPS6KA3	516	HCC	154	154
CDK9	507	HCC	215	215
PHKG2	506	HCC	129	129
MAP3K11	505	HCC	81	81
NIM1K	503	HCC	146	146
PRKCH	502	HCC	100	100
MARK1	498	HCC	151	151
SGK1	496	HCC	140	140
TBK1	495	HCC	100	100
NEK9	494	HCC	87	87
MAPKAPK2	492	HCC	184	184
RPS6KA5	480	HCC	177	177
TYK2	480	HCC	19	19
MAP3K10	479	HCC	69	69
PLK4	462	HCC	55	55
DAPK1	458	HCC	70	70
ATR	456	HCC	33	33
MAP4K2	455	HCC	50	50
MAP3K20	450	HCC	66	66
MAP2K7	447	HCC	85	85
PIM3	445	HCC	98	98
CDK6	444	HCC	115	115
MARK2	442	HCC	167	167
MAPKAPK5	441	HCC	170	170
MAP3K7	439	HCC	56	56
MAP2K3	437	HCC	70	70
STK11	430	HCC	31	31
MARK3	427	HCC	153	153
TLK1	418	HCC	77	77
CAMK4	417	HCC	109	109
SGK3	417	HCC	132	132
GRK5	413	HCC	99	99
EIF2AK2	399	HCC	73	73
MATK	396	HCC	62	62
DYRK3	392	HCC	142	142
IRAK4	391	HCC	46	46
TSSK1B	381	HCC	127	127
MTOR	374	HCC	91	91
DCLK2	373	HCC	82	82
ACVR1B	366	HCC	86	86
SIK1	364	HCC	158	158
CSNK1G2	363	HCC	96	96
PRKACG	360	HCC	83	83
AKT3	347	HCC	136	136
TLK2	343	HCC	57	57
MKNK2	341	HCC	91	91
CSNK1G1	327	HCC	62	62
PRKD3	319	HCC	88	88
PAK4	314	HCC	113	113
RPS6KA6	312	HCC	115	115
CSK	310	HCC	12	12
TAOK1	309	HCC	51	51
PTK2	305	HCC	18	18
MAP2K5	304	HCC	50	50
SRPK3	295	HCC	166	166
TSSK2	294	HCC	99	99
BMPR1B	289	HCC	72	72
LATS1	288	HCC	123	123
DYRK4	279	HCC	132	132
DSTYK	277	HCC	61	61
LATS2	277	HCC	81	81
ULK3	272	HCC	63	63
NEK11	269	HCC	26	26
GRK7	267	HCC	78	78
BUB1B	261	HCC	65	65
DYRK1A	256	HCC	105	105
TGFBR1	253	HCC	64	64
LIMK2	253	HCC	102	102
WNK3	244	HCC	43	43
CHEK2	243	HCC	38	38
PKN1	243	HCC	63	63
CAMKK1	239	HCC	19	19
CAMK1	228	HCC	43	43
JAK1	226	HCC	8	8
ACVR1	225	HCC	68	68
RPS6KA4	221	HCC	91	91
PBK	214	HCC	16	16
CILK1	210	HCC	67	67
PAK6	209	HCC	46	46
WNK1	209	HCC	38	38
CSNK1G3	206	HCC	51	51
PRKD2	206	HCC	61	61
NUAK2	205	HCC	81	81
FAM20C	204	HCC	90	90
DMPK	201	HCC	47	47
ACVR2A	200	HCC	55	55
SYK	197	HCC	3	3
MYLK2	191	HCC	60	60
WEE1	191	HCC	13	13
GRK1	189	HCC	56	56
GRK3	187	HCC	20	20
MOK	187	HCC	43	43
ULK1	187	HCC	32	32
WNK2	186	HCC	38	38
CAMK1D	174	HCC	68	68
PAK5	173	HCC	56	56
MELK	173	HCC	59	59
SLK	171	HCC	18	18
PRKX	169	HCC	84	84
DCLK1	163	HCC	41	41
RPS6KB2	161	HCC	59	59
PLK2	157	HCC	30	30
CLK2	155	HCC	59	59
MAP3K8	153	HCC	28	28
HIPK1	150	HCC	49	49
OXSR1	149	HCC	18	18
PIM2	147	HCC	44	44
SGK2	142	HCC	65	65
NUAK1	141	HCC	41	41
TESK1	139	HCC	16	16
CDC42BPB	138	HCC	46	46
EEF2K	136	HCC	23	23
PDK2	136	HCC	30	30
MAP3K2	132	HCC	44	44
CDC42BPA	130	HCC	39	39
HASPIN	130	HCC	16	16
STK38L	128	HCC	36	36
PDK4	121	HCC	29	29
STK38	120	HCC	33	33
EIF2AK3	117	HCC	21	21
MOS	117	HCC	21	21
MAST1	112	HCC	69	69
PDPK1	109	HCC	17	17
DAPK3	107	HCC	14	14
LRRK2	107	HCC	24	24
MAP3K3	106	HCC	35	35
PHKG1	104	HCC	29	29
STK39	104	HCC	12	12
CLK3	103	HCC	63	63
EIF2AK1	102	HCC	48	48
HIPK4	101	HCC	42	42
MAPK15	101	HCC	30	30
PKN2	99	HCC	32	32
ACVR2B	97	HCC	18	18
MAP3K5	97	HCC	7	7
CDK3	96	HCC	17	17
BRSK2	95	HCC	34	34
CDC7	93	HCC	16	16
HIPK3	91	HCC	52	52
STK16	89	HCC	15	15
BUB1	70	HCC	7	7
CLK4	70	HCC	12	12
VRK1	68	HCC	12	12
PDK3	64	HCC	9	9
DDR1	63	HCC	3	3
STK10	60	HCC	6	6
BRSK1	59	HCC	19	19
DYRK1B	58	HCC	16	16
PASK	58	HCC	13	13
BMPR2	55	HCC	12	12
STK33	54	HCC	28	28
BMPR1A	53	HCC	22	22
CDKL5	52	HCC	24	24
VRK2	50	HCC	5	5
RIPK2	47	HCC	10	10
BRAF	46	HCC	12	12
TNNI3K	46	HCC	2	2
MAP3K14	45	HCC	3	3
SRPK2	42	HCC	21	21
PKMYT1	42	HCC	9	9
MYLK	38	HCC	9	9
MAP3K15	37	HCC	22	22
PNCK	37	HCC	14	14
DAPK2	36	HCC	6	6
ROR2	36	HCC	2	2
EIF2AK4	35	HCC	12	12
MKNK1	34	HCC	6	6
WNK4	34	HCC	12	12
PINK1	32	HCC	2	2
CDK12	29	HCC	12	12
ROR1	29	HCC	3	3
UHMK1	25	HCC	4	4
ACVRL1	25	HCC	9	9
ILK	25	HCC	2	2
MAST2	24	HCC	9	9
MAP3K12	22	HCC	5	5
CDK14	21	HCC	2	2
CDK17	20	HCC	10	10
CDK16	19	HCC	5	5
SMG1	16	HCC	2	2
RIPK3	15	HCC	4	4
MAP3K13	13	HCC	5	5
MAP3K6	10	HCC	2	2
PKN3	10	HCC	6	6
BMP2K	9	HCC	5	5
MAP3K4	8	HCC	4	4
TESK2	7	HCC	6	6
MAPK1	3,653	HGSC	693	595
PRKCB	3,645	HGSC	215	124
CDK1	3,527	HGSC	476	380
SRC	3,418	HGSC	38	23
PRKCA	3,390	HGSC	218	148
MAPK3	3,253	HGSC	524	446
CSNK2A1	3,097	HGSC	199	159
PLK1	2,941	HGSC	380	314
ABL1	2,437	HGSC	63	0
GSK3B	2,369	HGSC	197	161
PRKACA	2,337	HGSC	409	329
YES1	2,161	HGSC	120	0
NEK2	2,152	HGSC	143	99
AKT1	2,097	HGSC	340	280
TTK	2,048	HGSC	219	167
AURKA	2,034	HGSC	162	123
CDK2	1,999	HGSC	321	254
MAPK14	1,975	HGSC	427	365
FYN	1,850	HGSC	30	30
IKBKB	1,714	HGSC	168	134
CSNK1D	1,630	HGSC	137	98
MAPK8	1,611	HGSC	252	212
GRK2	1,475	HGSC	83	56
RET	1,469	HGSC	23	16
AURKB	1,431	HGSC	156	127
GSK3A	1,417	HGSC	171	143
HCK	1,400	HGSC	18	18
MAP2K1	1,377	HGSC	174	133
FER	1,376	HGSC	15	15
PRKCI	1,367	HGSC	320	251
CSNK1E	1,321	HGSC	304	246
MAP4K5	1,313	HGSC	371	301
RPS6KA1	1,286	HGSC	174	136
TEC	1,237	HGSC	12	0
CHUK	1,230	HGSC	156	132
PRKDC	1,218	HGSC	78	60
ATM	1,214	HGSC	24	18
BTK	1,160	HGSC	33	33
PAK1	1,151	HGSC	220	178
CSNK1A1	1,138	HGSC	113	92
RAF1	1,128	HGSC	142	106
ROCK1	1,096	HGSC	181	151
ERN1	1,081	HGSC	393	311
CSNK2A2	1,074	HGSC	158	121
PRKCD	1,069	HGSC	84	52
MAP3K1	1,063	HGSC	266	211
PRKCE	1,061	HGSC	87	87
CAMK2A	1,045	HGSC	157	125
MAP4K4	1,038	HGSC	177	142
HIPK2	1,008	HGSC	156	128
PAK3	987	HGSC	206	161
MINK1	972	HGSC	174	142
AXL	939	HGSC	20	20
PAK2	926	HGSC	173	138
MAPK7	923	HGSC	115	89
IRAK1	919	HGSC	310	245
MAPK13	897	HGSC	199	173
MAPK12	894	HGSC	205	175
CIT	892	HGSC	381	305
CDK5	882	HGSC	146	112
CHEK1	858	HGSC	73	51
STK4	845	HGSC	80	59
CAMKK2	829	HGSC	307	249
CDK7	811	HGSC	75	59
CAMK2D	804	HGSC	153	120
ROCK2	800	HGSC	110	87
MAPK9	794	HGSC	153	120
STK3	785	HGSC	46	29
MAPK11	779	HGSC	117	99
MAP2K4	774	HGSC	67	51
NEK1	773	HGSC	57	39
RPS6KA2	754	HGSC	258	200
MARK4	750	HGSC	99	75
MAP3K9	747	HGSC	56	35
CAMK2G	731	HGSC	164	135
PDK1	724	HGSC	72	56
STK24	718	HGSC	17	0
PRKCZ	717	HGSC	91	64
AKT2	712	HGSC	178	139
NEK6	707	HGSC	65	49
DYRK2	701	HGSC	131	101
TTBK1	701	HGSC	63	42
IKBKE	699	HGSC	68	53
PRKG2	696	HGSC	118	95
CLK1	693	HGSC	142	112
TAOK3	692	HGSC	302	243
SRPK1	685	HGSC	242	199
PRKG1	681	HGSC	75	58
CAMK2B	676	HGSC	124	103
PIM1	676	HGSC	77	61
STK26	674	HGSC	62	49
CDK4	670	HGSC	80	60
PRKD1	658	HGSC	85	64
RPS6KB1	656	HGSC	105	85
PRKACB	653	HGSC	130	93
NEK7	636	HGSC	54	38
NEK4	618	HGSC	25	10
MAPK10	609	HGSC	109	96
STK25	604	HGSC	48	37
TNIK	604	HGSC	48	41
SIK2	595	HGSC	101	78
PRKAA2	571	HGSC	68	57
AURKC	570	HGSC	79	62
MAP2K6	569	HGSC	56	41
PLK3	555	HGSC	56	40
MAPKAPK3	552	HGSC	116	90
PRKAA1	530	HGSC	48	35
NLK	527	HGSC	82	64
TAOK2	521	HGSC	47	35
MAP2K2	516	HGSC	68	51
RPS6KA3	516	HGSC	110	88
CDK9	507	HGSC	188	152
PHKG2	506	HGSC	95	75
MAP3K11	505	HGSC	29	14
NIM1K	503	HGSC	47	27
PRKCH	502	HGSC	62	62
MARK1	498	HGSC	67	46
SGK1	496	HGSC	88	67
TBK1	495	HGSC	40	23
NEK9	494	HGSC	56	34
MAPKAPK2	492	HGSC	109	80
RPS6KA5	480	HGSC	125	103
MAP3K10	479	HGSC	29	17
TGFBR2	465	HGSC	41	34
PLK4	462	HGSC	55	43
DAPK1	458	HGSC	43	30
ATR	456	HGSC	10	8
MAP4K2	455	HGSC	17	13
MAP3K20	450	HGSC	50	35
MAP2K7	447	HGSC	46	37
PIM3	445	HGSC	73	56
CDK6	444	HGSC	92	66
MARK2	442	HGSC	72	54
MAPKAPK5	441	HGSC	105	72
MAP3K7	439	HGSC	30	19
MAP2K3	437	HGSC	39	30
STK11	430	HGSC	14	7
MARK3	427	HGSC	83	61
TLK1	418	HGSC	27	19
CAMK4	417	HGSC	82	62
SGK3	417	HGSC	75	54
GRK5	413	HGSC	53	40
EIF2AK2	399	HGSC	38	26
MATK	396	HGSC	52	43
DYRK3	392	HGSC	76	64
IRAK4	391	HGSC	40	30
TSSK1B	381	HGSC	55	36
MTOR	374	HGSC	62	48
DCLK2	373	HGSC	63	47
ACVR1B	366	HGSC	47	33
SIK1	364	HGSC	106	80
CSNK1G2	363	HGSC	36	24
PRKACG	360	HGSC	45	45
AKT3	347	HGSC	94	70
TLK2	343	HGSC	19	11
MKNK2	341	HGSC	69	53
CSNK1G1	327	HGSC	25	16
PRKD3	319	HGSC	48	31
PAK4	314	HGSC	99	81
RPS6KA6	312	HGSC	73	57
TAOK1	309	HGSC	40	29
MAP2K5	304	HGSC	20	13
SRPK3	295	HGSC	112	86
TSSK2	294	HGSC	68	49
BMPR1B	289	HGSC	27	15
LATS1	288	HGSC	91	66
DYRK4	279	HGSC	104	83
DSTYK	277	HGSC	18	7
LATS2	277	HGSC	59	47
ULK3	272	HGSC	24	0
NEK11	269	HGSC	30	24
GRK7	267	HGSC	29	19
BUB1B	261	HGSC	21	0
DYRK1A	256	HGSC	80	70
TGFBR1	253	HGSC	28	13
WNK3	244	HGSC	31	25
CHEK2	243	HGSC	20	15
PKN1	243	HGSC	63	48
CAMKK1	239	HGSC	14	11
CAMK1	228	HGSC	32	24
ACVR1	225	HGSC	25	8
RPS6KA4	221	HGSC	86	72
PBK	214	HGSC	11	6
CILK1	210	HGSC	41	30
PAK6	209	HGSC	65	54
WNK1	209	HGSC	18	10
CSNK1G3	206	HGSC	25	19
PRKD2	206	HGSC	43	30
NUAK2	205	HGSC	45	30
FAM20C	204	HGSC	39	29
DMPK	201	HGSC	36	27
ACVR2A	200	HGSC	25	16
MYLK2	191	HGSC	42	34
GRK1	189	HGSC	20	14
GRK3	187	HGSC	14	14
MOK	187	HGSC	36	26
ULK1	187	HGSC	24	18
WNK2	186	HGSC	14	0
CAMK1D	174	HGSC	30	25
PAK5	173	HGSC	45	34
SLK	171	HGSC	35	32
PRKX	169	HGSC	57	41
DCLK1	163	HGSC	34	22
RPS6KB2	161	HGSC	27	22
PLK2	157	HGSC	9	7
CLK2	155	HGSC	28	26
MAP3K8	153	HGSC	13	8
HIPK1	150	HGSC	37	30
OXSR1	149	HGSC	15	10
PIM2	147	HGSC	26	17
GRK4	142	HGSC	7	3
SGK2	142	HGSC	48	40
NUAK1	141	HGSC	32	25
CDC42BPB	138	HGSC	19	19
EEF2K	136	HGSC	15	5
MAP3K2	132	HGSC	37	31
CDC42BPA	130	HGSC	19	14
HASPIN	130	HGSC	7	4
STK38L	128	HGSC	29	20
GRK6	121	HGSC	5	4
PDK4	121	HGSC	17	12
STK38	120	HGSC	12	0
EIF2AK3	117	HGSC	10	1
MOS	117	HGSC	15	11
PDPK1	109	HGSC	4	1
DAPK3	107	HGSC	12	8
LRRK2	107	HGSC	19	15
MAP3K3	106	HGSC	24	18
PHKG1	104	HGSC	8	8
STK39	104	HGSC	15	14
CLK3	103	HGSC	42	32
EIF2AK1	102	HGSC	36	24
HIPK4	101	HGSC	35	31
MAPK15	101	HGSC	18	15
PKN2	99	HGSC	34	34
ACVR2B	97	HGSC	8	6
MAP3K5	97	HGSC	3	2
CDK3	96	HGSC	11	10
BRSK2	95	HGSC	37	32
CDC7	93	HGSC	7	7
HIPK3	91	HGSC	43	38
STK16	89	HGSC	11	8
TRPM6	72	HGSC	5	3
BUB1	70	HGSC	4	3
CLK4	70	HGSC	6	6
VRK1	68	HGSC	6	3
STK10	60	HGSC	10	7
BRSK1	59	HGSC	10	7
DYRK1B	58	HGSC	17	16
PASK	58	HGSC	14	12
NEK3	57	HGSC	2	1
BMPR2	55	HGSC	15	10
STK33	54	HGSC	21	18
BMPR1A	53	HGSC	9	4
CDKL5	52	HGSC	16	15
MAK	50	HGSC	21	18
VRK2	50	HGSC	2	2
RIPK2	47	HGSC	4	3
BRAF	46	HGSC	8	8
MAP3K14	45	HGSC	2	2
SRPK2	42	HGSC	17	14
MYLK	38	HGSC	6	6
CSNK1A1L	37	HGSC	6	5
MAP3K15	37	HGSC	17	12
PNCK	37	HGSC	12	10
BCKDK	36	HGSC	2	2
DAPK2	36	HGSC	5	3
EIF2AK4	35	HGSC	4	2
MKNK1	34	HGSC	8	8
WNK4	34	HGSC	5	4
CDK12	29	HGSC	5	1
UHMK1	25	HGSC	4	3
MAP3K12	22	HGSC	12	12
CDK14	21	HGSC	3	0
CDK17	20	HGSC	11	9
CDK16	19	HGSC	6	6
TRPM7	19	HGSC	1	0
RIPK3	15	HGSC	3	3
MAP4K1	14	HGSC	1	1
MAP3K6	10	HGSC	1	1
PKN3	10	HGSC	2	2
BMP2K	9	HGSC	2	2
CDK18	7	HGSC	1	0
STK17A	5	HGSC	2	2
MASTL	4	HGSC	2	0
MAPK1	3,653	HNSCC	596	596
PRKCB	3,645	HNSCC	144	144
CDK1	3,527	HNSCC	364	364
SRC	3,418	HNSCC	40	40
PRKCA	3,390	HNSCC	134	134
MAPK3	3,253	HNSCC	435	435
CSNK2A1	3,097	HNSCC	299	299
PLK1	2,941	HNSCC	315	315
ABL1	2,437	HNSCC	74	74
GSK3B	2,369	HNSCC	173	173
PRKACA	2,337	HNSCC	283	283
NEK2	2,152	HNSCC	151	151
AKT1	2,097	HNSCC	225	225
TTK	2,048	HNSCC	192	192
AURKA	2,034	HNSCC	143	143
CDK2	1,999	HNSCC	231	231
MAPK14	1,975	HNSCC	384	384
IKBKB	1,714	HNSCC	170	170
NTRK3	1,677	HNSCC	47	47
ALK	1,638	HNSCC	38	38
CSNK1D	1,630	HNSCC	118	118
MAPK8	1,611	HNSCC	198	198
FLT3	1,584	HNSCC	24	24
GRK2	1,475	HNSCC	88	88
RET	1,469	HNSCC	28	28
AURKB	1,431	HNSCC	105	105
GSK3A	1,417	HNSCC	146	146
MAP2K1	1,377	HNSCC	124	124
PRKCI	1,367	HNSCC	260	260
CSNK1E	1,321	HNSCC	216	216
MAP4K5	1,313	HNSCC	269	269
RPS6KA1	1,286	HNSCC	167	167
CHUK	1,230	HNSCC	146	146
PRKDC	1,218	HNSCC	80	80
ATM	1,214	HNSCC	37	37
BTK	1,160	HNSCC	35	35
PAK1	1,151	HNSCC	164	164
CSNK1A1	1,138	HNSCC	107	107
RAF1	1,128	HNSCC	97	97
ROCK1	1,096	HNSCC	130	130
PRKCG	1,094	HNSCC	78	78
ERN1	1,081	HNSCC	294	294
CSNK2A2	1,074	HNSCC	211	211
PRKCD	1,069	HNSCC	65	65
MAP3K1	1,063	HNSCC	178	178
PRKCE	1,061	HNSCC	74	74
CAMK2A	1,045	HNSCC	134	134
MAP4K4	1,038	HNSCC	136	136
JAK3	1,035	HNSCC	24	24
HIPK2	1,008	HNSCC	120	120
PAK3	987	HNSCC	162	162
MINK1	972	HNSCC	118	118
PAK2	926	HNSCC	126	126
MAPK7	923	HNSCC	103	103
IRAK1	919	HNSCC	208	208
JAK2	907	HNSCC	20	20
MAPK13	897	HNSCC	187	187
MAPK12	894	HNSCC	184	184
CIT	892	HNSCC	261	261
CDK5	882	HNSCC	110	110
CHEK1	858	HNSCC	75	75
STK4	845	HNSCC	72	72
CAMKK2	829	HNSCC	205	205
CDK7	811	HNSCC	79	79
CAMK2D	804	HNSCC	136	136
ROCK2	800	HNSCC	85	85
MAPK9	794	HNSCC	119	119
STK3	785	HNSCC	42	42
MAPK11	779	HNSCC	132	132
MAP2K4	774	HNSCC	64	64
NEK1	773	HNSCC	49	49
RPS6KA2	754	HNSCC	190	190
MARK4	750	HNSCC	87	87
MAP3K9	747	HNSCC	54	54
CAMK2G	731	HNSCC	132	132
PDK1	724	HNSCC	44	44
STK24	718	HNSCC	49	49
PRKCZ	717	HNSCC	63	63
AKT2	712	HNSCC	131	131
NEK6	707	HNSCC	53	53
DYRK2	701	HNSCC	117	117
TTBK1	701	HNSCC	71	71
IKBKE	699	HNSCC	85	85
PRKG2	696	HNSCC	88	88
CLK1	693	HNSCC	114	114
TAOK3	692	HNSCC	190	190
SRPK1	685	HNSCC	162	162
PRKG1	681	HNSCC	57	57
CAMK2B	676	HNSCC	102	102
PIM1	676	HNSCC	61	61
STK26	674	HNSCC	43	43
CDK4	670	HNSCC	56	56
PRKD1	658	HNSCC	66	66
RPS6KB1	656	HNSCC	93	93
PRKACB	653	HNSCC	86	86
NEK7	636	HNSCC	46	46
NEK4	618	HNSCC	25	25
MAPK10	609	HNSCC	101	101
STK25	604	HNSCC	38	38
TNIK	604	HNSCC	42	42
SIK2	595	HNSCC	75	75
PRKAA2	571	HNSCC	45	45
AURKC	570	HNSCC	71	71
MAP2K6	569	HNSCC	55	55
PLK3	555	HNSCC	62	62
MAPKAPK3	552	HNSCC	98	98
PRKAA1	530	HNSCC	31	31
NLK	527	HNSCC	75	75
TAOK2	521	HNSCC	44	44
MAP2K2	516	HNSCC	54	54
RPS6KA3	516	HNSCC	76	76
CDK9	507	HNSCC	92	92
PHKG2	506	HNSCC	81	81
MAP3K11	505	HNSCC	31	31
NIM1K	503	HNSCC	45	45
PRKCH	502	HNSCC	50	50
MARK1	498	HNSCC	50	50
SGK1	496	HNSCC	51	51
TBK1	495	HNSCC	41	41
NEK9	494	HNSCC	52	52
MAPKAPK2	492	HNSCC	85	85
RPS6KA5	480	HNSCC	103	103
MAP3K10	479	HNSCC	36	36
TGFBR2	465	HNSCC	34	34
PLK4	462	HNSCC	48	48
DAPK1	458	HNSCC	34	34
ATR	456	HNSCC	16	16
MAP4K2	455	HNSCC	24	24
MAP3K20	450	HNSCC	39	39
MAP2K7	447	HNSCC	47	47
PIM3	445	HNSCC	63	63
CDK6	444	HNSCC	59	59
MARK2	442	HNSCC	50	50
MAPKAPK5	441	HNSCC	75	75
MAP3K7	439	HNSCC	27	27
MAP2K3	437	HNSCC	43	43
STK11	430	HNSCC	14	14
MARK3	427	HNSCC	58	58
TLK1	418	HNSCC	39	39
CAMK4	417	HNSCC	69	69
SGK3	417	HNSCC	54	54
GRK5	413	HNSCC	50	50
EIF2AK2	399	HNSCC	42	42
MATK	396	HNSCC	49	49
DYRK3	392	HNSCC	69	69
IRAK4	391	HNSCC	36	36
TSSK1B	381	HNSCC	42	42
MTOR	374	HNSCC	44	44
DCLK2	373	HNSCC	46	46
ACVR1B	366	HNSCC	50	50
SIK1	364	HNSCC	83	83
CSNK1G2	363	HNSCC	38	38
PRKACG	360	HNSCC	36	36
AKT3	347	HNSCC	57	57
TLK2	343	HNSCC	31	31
MKNK2	341	HNSCC	52	52
CSNK1G1	327	HNSCC	33	33
PRKD3	319	HNSCC	44	44
PAK4	314	HNSCC	59	59
RPS6KA6	312	HNSCC	65	65
TAOK1	309	HNSCC	28	28
MAP2K5	304	HNSCC	28	28
SRPK3	295	HNSCC	96	96
TSSK2	294	HNSCC	45	45
BMPR1B	289	HNSCC	40	40
LATS1	288	HNSCC	76	76
DYRK4	279	HNSCC	76	76
DSTYK	277	HNSCC	26	26
LATS2	277	HNSCC	52	52
ULK3	272	HNSCC	26	26
NEK11	269	HNSCC	32	32
GRK7	267	HNSCC	36	36
BUB1B	261	HNSCC	38	38
DYRK1A	256	HNSCC	73	73
TGFBR1	253	HNSCC	31	31
WNK3	244	HNSCC	32	32
CHEK2	243	HNSCC	23	23
PKN1	243	HNSCC	52	52
CAMKK1	239	HNSCC	11	11
CAMK1	228	HNSCC	35	35
ACVR1	225	HNSCC	29	29
RPS6KA4	221	HNSCC	59	59
PBK	214	HNSCC	8	8
CILK1	210	HNSCC	35	35
PAK6	209	HNSCC	38	38
WNK1	209	HNSCC	23	23
CSNK1G3	206	HNSCC	22	22
PRKD2	206	HNSCC	32	32
NUAK2	205	HNSCC	38	38
FAM20C	204	HNSCC	42	42
DMPK	201	HNSCC	22	22
ACVR2A	200	HNSCC	30	30
MYLK2	191	HNSCC	24	24
GRK1	189	HNSCC	27	27
GRK3	187	HNSCC	8	8
MOK	187	HNSCC	28	28
ULK1	187	HNSCC	10	10
WNK2	186	HNSCC	27	27
CAMK1D	174	HNSCC	33	33
PAK5	173	HNSCC	26	26
SLK	171	HNSCC	30	30
PRKX	169	HNSCC	39	39
DCLK1	163	HNSCC	35	35
RPS6KB2	161	HNSCC	27	27
PLK2	157	HNSCC	12	12
CLK2	155	HNSCC	32	32
MAP3K8	153	HNSCC	12	12
HIPK1	150	HNSCC	40	40
OXSR1	149	HNSCC	11	11
PIM2	147	HNSCC	21	21
GRK4	142	HNSCC	11	11
SGK2	142	HNSCC	39	39
NUAK1	141	HNSCC	29	29
CDC42BPB	138	HNSCC	25	25
EEF2K	136	HNSCC	11	11
MAP3K2	132	HNSCC	29	29
CDC42BPA	130	HNSCC	20	20
HASPIN	130	HNSCC	7	7
STK38L	128	HNSCC	21	21
GRK6	121	HNSCC	3	3
PDK4	121	HNSCC	9	9
STK38	120	HNSCC	23	23
EIF2AK3	117	HNSCC	15	15
MOS	117	HNSCC	19	19
PDPK1	109	HNSCC	8	8
DAPK3	107	HNSCC	10	10
LRRK2	107	HNSCC	12	12
MAP3K3	106	HNSCC	16	16
PHKG1	104	HNSCC	17	17
STK39	104	HNSCC	8	8
CLK3	103	HNSCC	34	34
EIF2AK1	102	HNSCC	26	26
HIPK4	101	HNSCC	38	38
MAPK15	101	HNSCC	17	17
PKN2	99	HNSCC	32	32
ACVR2B	97	HNSCC	11	11
MAP3K5	97	HNSCC	8	8
CDK3	96	HNSCC	11	11
BRSK2	95	HNSCC	28	28
CDC7	93	HNSCC	6	6
HIPK3	91	HNSCC	41	41
STK16	89	HNSCC	11	11
BUB1	70	HNSCC	4	4
CLK4	70	HNSCC	11	11
VRK1	68	HNSCC	11	11
STK10	60	HNSCC	3	3
BRSK1	59	HNSCC	5	5
DYRK1B	58	HNSCC	18	18
PASK	58	HNSCC	9	9
NEK3	57	HNSCC	2	2
BMPR2	55	HNSCC	10	10
STK33	54	HNSCC	13	13
BMPR1A	53	HNSCC	9	9
CDKL5	52	HNSCC	13	13
MAK	50	HNSCC	17	17
VRK2	50	HNSCC	1	1
RIPK2	47	HNSCC	4	4
BRAF	46	HNSCC	12	12
MAP3K14	45	HNSCC	2	2
SRPK2	42	HNSCC	12	12
CDK8	39	HNSCC	2	2
MYLK	38	HNSCC	6	6
CSNK1A1L	37	HNSCC	3	3
MAP3K15	37	HNSCC	11	11
PNCK	37	HNSCC	7	7
BCKDK	36	HNSCC	5	5
DAPK2	36	HNSCC	4	4
EIF2AK4	35	HNSCC	4	4
MKNK1	34	HNSCC	2	2
WNK4	34	HNSCC	3	3
CDK12	29	HNSCC	3	3
UHMK1	25	HNSCC	3	3
MAP3K12	22	HNSCC	11	11
CDK14	21	HNSCC	3	3
CDK17	20	HNSCC	10	10
CDK16	19	HNSCC	8	8
RIPK3	15	HNSCC	3	3
MAP3K6	10	HNSCC	2	2
PKN3	10	HNSCC	4	4
BMP2K	9	HNSCC	3	3
STK17A	5	HNSCC	1	1
MASTL	4	HNSCC	1	1
MAP3K21	3	HNSCC	2	2
MAPK1	3,653	LSCC	1,163	1,163
PRKCB	3,645	LSCC	436	436
CDK1	3,527	LSCC	934	934
SRC	3,418	LSCC	66	66
PRKCA	3,390	LSCC	342	342
MAPK3	3,253	LSCC	965	965
CSNK2A1	3,097	LSCC	722	722
PLK1	2,941	LSCC	694	694
ABL1	2,437	LSCC	158	158
GSK3B	2,369	LSCC	395	395
PRKACA	2,337	LSCC	501	501
YES1	2,161	LSCC	258	258
NEK2	2,152	LSCC	345	345
AKT1	2,097	LSCC	470	470
TTK	2,048	LSCC	424	424
AURKA	2,034	LSCC	363	363
CDK2	1,999	LSCC	578	578
MAPK14	1,975	LSCC	704	704
FYN	1,850	LSCC	60	60
IKBKB	1,714	LSCC	328	328
INSR	1,712	LSCC	52	52
FES	1,708	LSCC	27	27
MET	1,687	LSCC	51	51
NTRK3	1,677	LSCC	44	44
FGR	1,647	LSCC	57	57
ALK	1,638	LSCC	41	41
CSNK1D	1,630	LSCC	326	326
MAPK8	1,611	LSCC	427	427
FLT3	1,584	LSCC	30	30
EPHB3	1,478	LSCC	27	27
GRK2	1,475	LSCC	209	209
RET	1,469	LSCC	40	40
LCK	1,446	LSCC	38	38
AURKB	1,431	LSCC	228	228
GSK3A	1,417	LSCC	332	332
HCK	1,400	LSCC	40	40
MAP2K1	1,377	LSCC	289	289
FER	1,376	LSCC	23	23
PRKCI	1,367	LSCC	521	521
BMX	1,364	LSCC	32	32
EGFR	1,328	LSCC	43	43
CSNK1E	1,321	LSCC	469	469
MAP4K5	1,313	LSCC	470	470
RPS6KA1	1,286	LSCC	327	327
FLT4	1,247	LSCC	35	35
TEC	1,237	LSCC	28	28
CHUK	1,230	LSCC	266	266
PRKDC	1,218	LSCC	231	231
ATM	1,214	LSCC	112	112
BTK	1,160	LSCC	52	52
PAK1	1,151	LSCC	293	293
LTK	1,139	LSCC	22	22
CSNK1A1	1,138	LSCC	217	217
RAF1	1,128	LSCC	255	255
FRK	1,119	LSCC	27	27
ROCK1	1,096	LSCC	265	265
PRKCG	1,094	LSCC	169	169
ERN1	1,081	LSCC	583	583
CSNK2A2	1,074	LSCC	355	355
PRKCD	1,069	LSCC	133	133
MAP3K1	1,063	LSCC	353	353
PRKCE	1,061	LSCC	166	166
ABL2	1,050	LSCC	104	104
CAMK2A	1,045	LSCC	222	222
MAP4K4	1,038	LSCC	242	242
JAK3	1,035	LSCC	22	22
HIPK2	1,008	LSCC	260	260
PAK3	987	LSCC	292	292
PTK6	978	LSCC	20	20
MINK1	972	LSCC	211	211
AXL	939	LSCC	24	24
PAK2	926	LSCC	215	215
MAPK7	923	LSCC	201	201
PRKCQ	921	LSCC	130	130
IRAK1	919	LSCC	390	390
EPHA6	913	LSCC	25	25
JAK2	907	LSCC	22	22
MAPK13	897	LSCC	297	297
MAPK12	894	LSCC	300	300
CIT	892	LSCC	528	528
CDK5	882	LSCC	260	260
CHEK1	858	LSCC	120	120
STK4	845	LSCC	98	98
CAMKK2	829	LSCC	430	430
CDK7	811	LSCC	203	203
CAMK2D	804	LSCC	235	235
ROCK2	800	LSCC	172	172
MAPK9	794	LSCC	232	232
STK3	785	LSCC	79	79
MAPK11	779	LSCC	196	196
MAP2K4	774	LSCC	131	131
NEK1	773	LSCC	98	98
RPS6KA2	754	LSCC	353	353
MARK4	750	LSCC	182	182
PTK2B	748	LSCC	18	18
MAP3K9	747	LSCC	68	68
CAMK2G	731	LSCC	207	207
PDK1	724	LSCC	150	150
STK24	718	LSCC	61	61
PRKCZ	717	LSCC	98	98
AKT2	712	LSCC	239	239
NEK6	707	LSCC	72	72
DYRK2	701	LSCC	193	193
TTBK1	701	LSCC	102	102
IKBKE	699	LSCC	134	134
PRKG2	696	LSCC	186	186
CLK1	693	LSCC	236	236
TAOK3	692	LSCC	420	420
SRPK1	685	LSCC	362	362
PRKG1	681	LSCC	140	140
CAMK2B	676	LSCC	162	162
PIM1	676	LSCC	98	98
STK26	674	LSCC	59	59
CDK4	670	LSCC	154	154
PRKD1	658	LSCC	125	125
RPS6KB1	656	LSCC	176	176
PRKACB	653	LSCC	180	180
NEK7	636	LSCC	87	87
NEK4	618	LSCC	53	53
MAPK10	609	LSCC	173	173
STK25	604	LSCC	43	43
TNIK	604	LSCC	39	39
SIK2	595	LSCC	137	137
LIMK1	592	LSCC	122	122
PRKAA2	571	LSCC	133	133
AURKC	570	LSCC	113	113
MAP2K6	569	LSCC	82	82
PLK3	555	LSCC	105	105
MAPKAPK3	552	LSCC	148	148
PRKAA1	530	LSCC	85	85
LYN	530	LSCC	16	16
NLK	527	LSCC	103	103
TAOK2	521	LSCC	39	39
MAP2K2	516	LSCC	86	86
RPS6KA3	516	LSCC	141	141
CDK9	507	LSCC	245	245
PHKG2	506	LSCC	97	97
MAP3K11	505	LSCC	51	51
NIM1K	503	LSCC	102	102
PRKCH	502	LSCC	71	71
MARK1	498	LSCC	138	138
SGK1	496	LSCC	116	116
TBK1	495	LSCC	78	78
NEK9	494	LSCC	65	65
MAPKAPK2	492	LSCC	159	159
RPS6KA5	480	LSCC	151	151
MAP3K10	479	LSCC	47	47
TGFBR2	465	LSCC	83	83
PLK4	462	LSCC	56	56
DAPK1	458	LSCC	72	72
ATR	456	LSCC	50	50
MAP4K2	455	LSCC	39	39
MAP3K20	450	LSCC	50	50
MAP2K7	447	LSCC	81	81
PIM3	445	LSCC	72	72
CDK6	444	LSCC	134	134
MARK2	442	LSCC	112	112
MAPKAPK5	441	LSCC	139	139
MAP3K7	439	LSCC	35	35
MAP2K3	437	LSCC	68	68
STK11	430	LSCC	28	28
MARK3	427	LSCC	135	135
TLK1	418	LSCC	72	72
CAMK4	417	LSCC	104	104
SGK3	417	LSCC	99	99
GRK5	413	LSCC	84	84
EIF2AK2	399	LSCC	93	93
MATK	396	LSCC	55	55
DYRK3	392	LSCC	113	113
IRAK4	391	LSCC	23	23
TSSK1B	381	LSCC	97	97
MTOR	374	LSCC	93	93
DCLK2	373	LSCC	61	61
ACVR1B	366	LSCC	75	75
SIK1	364	LSCC	129	129
CSNK1G2	363	LSCC	75	75
PRKACG	360	LSCC	82	82
AKT3	347	LSCC	113	113
TLK2	343	LSCC	54	54
MKNK2	341	LSCC	72	72
CSNK1G1	327	LSCC	65	65
PRKD3	319	LSCC	77	77
PAK4	314	LSCC	86	86
RPS6KA6	312	LSCC	90	90
TAOK1	309	LSCC	36	36
PTK2	305	LSCC	15	15
MAP2K5	304	LSCC	50	50
SRPK3	295	LSCC	181	181
TSSK2	294	LSCC	72	72
BMPR1B	289	LSCC	51	51
LATS1	288	LSCC	105	105
DYRK4	279	LSCC	116	116
DSTYK	277	LSCC	46	46
LATS2	277	LSCC	61	61
ULK3	272	LSCC	50	50
NEK11	269	LSCC	19	19
GRK7	267	LSCC	68	68
BUB1B	261	LSCC	54	54
DYRK1A	256	LSCC	104	104
TGFBR1	253	LSCC	47	47
WNK3	244	LSCC	34	34
CHEK2	243	LSCC	40	40
PKN1	243	LSCC	49	49
CAMKK1	239	LSCC	10	10
CAMK1	228	LSCC	55	55
ACVR1	225	LSCC	48	48
RPS6KA4	221	LSCC	83	83
PBK	214	LSCC	11	11
CILK1	210	LSCC	63	63
PAK6	209	LSCC	34	34
WNK1	209	LSCC	23	23
CSNK1G3	206	LSCC	44	44
PRKD2	206	LSCC	63	63
NUAK2	205	LSCC	62	62
FAM20C	204	LSCC	85	85
DMPK	201	LSCC	49	49
ACVR2A	200	LSCC	43	43
SYK	197	LSCC	5	5
MYLK2	191	LSCC	51	51
GRK1	189	LSCC	40	40
GRK3	187	LSCC	19	19
MOK	187	LSCC	42	42
ULK1	187	LSCC	34	34
WNK2	186	LSCC	30	30
CAMK1D	174	LSCC	60	60
PAK5	173	LSCC	41	41
MELK	173	LSCC	57	57
SLK	171	LSCC	16	16
PRKX	169	LSCC	68	68
DCLK1	163	LSCC	28	28
RPS6KB2	161	LSCC	46	46
PLK2	157	LSCC	26	26
CLK2	155	LSCC	54	54
MAP3K8	153	LSCC	18	18
HIPK1	150	LSCC	39	39
OXSR1	149	LSCC	10	10
PIM2	147	LSCC	30	30
GRK4	142	LSCC	13	13
SGK2	142	LSCC	55	55
NUAK1	141	LSCC	33	33
TESK1	139	LSCC	11	11
CDC42BPB	138	LSCC	40	40
EEF2K	136	LSCC	15	15
MAP3K2	132	LSCC	36	36
CDC42BPA	130	LSCC	37	37
HASPIN	130	LSCC	13	13
STK38L	128	LSCC	26	26
GRK6	121	LSCC	18	18
PDK4	121	LSCC	25	25
STK38	120	LSCC	29	29
EIF2AK3	117	LSCC	22	22
MOS	117	LSCC	13	13
PDPK1	109	LSCC	21	21
DAPK3	107	LSCC	11	11
LRRK2	107	LSCC	22	22
MAP3K3	106	LSCC	31	31
PHKG1	104	LSCC	27	27
STK39	104	LSCC	13	13
CLK3	103	LSCC	57	57
EIF2AK1	102	LSCC	46	46
HIPK4	101	LSCC	39	39
MAPK15	101	LSCC	20	20
PKN2	99	LSCC	32	32
ACVR2B	97	LSCC	26	26
MAP3K5	97	LSCC	5	5
CDK3	96	LSCC	26	26
BRSK2	95	LSCC	29	29
CDC7	93	LSCC	15	15
HIPK3	91	LSCC	46	46
STK16	89	LSCC	13	13
TRPM6	72	LSCC	9	9
BUB1	70	LSCC	6	6
CLK4	70	LSCC	13	13
VRK1	68	LSCC	12	12
STK10	60	LSCC	4	4
BRSK1	59	LSCC	18	18
DYRK1B	58	LSCC	17	17
PASK	58	LSCC	15	15
NEK3	57	LSCC	8	8
BMPR2	55	LSCC	9	9
STK33	54	LSCC	22	22
BMPR1A	53	LSCC	15	15
CDKL5	52	LSCC	23	23
MAK	50	LSCC	29	29
VRK2	50	LSCC	5	5
RIPK2	47	LSCC	8	8
BRAF	46	LSCC	12	12
MAP3K14	45	LSCC	2	2
SRPK2	42	LSCC	20	20
CDK8	39	LSCC	2	2
MYLK	38	LSCC	7	7
CSNK1A1L	37	LSCC	6	6
MAP3K15	37	LSCC	19	19
PNCK	37	LSCC	11	11
BCKDK	36	LSCC	13	13
DAPK2	36	LSCC	5	5
EIF2AK4	35	LSCC	14	14
MKNK1	34	LSCC	4	4
WNK4	34	LSCC	5	5
CDK12	29	LSCC	11	11
UHMK1	25	LSCC	5	5
MAP3K12	22	LSCC	5	5
CDK14	21	LSCC	4	4
CDK17	20	LSCC	13	13
CDK16	19	LSCC	6	6
TRPM7	19	LSCC	1	1
ULK2	19	LSCC	1	1
SMG1	16	LSCC	2	2
RIPK3	15	LSCC	6	6
MAP4K1	14	LSCC	2	2
CDK19	13	LSCC	1	1
CAMK1G	12	LSCC	2	2
MAP3K6	10	LSCC	3	3
PKN3	10	LSCC	4	4
BMP2K	9	LSCC	6	6
CDK18	7	LSCC	3	3
MAP4K3	6	LSCC	1	1
STK17A	5	LSCC	2	2
MAPK1	3,653	LUAD	1,014	1,014
PRKCB	3,645	LUAD	357	357
CDK1	3,527	LUAD	736	736
SRC	3,418	LUAD	53	53
PRKCA	3,390	LUAD	311	311
MAPK3	3,253	LUAD	836	836
CSNK2A1	3,097	LUAD	552	552
PLK1	2,941	LUAD	577	577
ABL1	2,437	LUAD	147	147
GSK3B	2,369	LUAD	334	334
PRKACA	2,337	LUAD	482	482
NEK2	2,152	LUAD	247	247
AKT1	2,097	LUAD	414	414
TTK	2,048	LUAD	341	341
AURKA	2,034	LUAD	270	270
CDK2	1,999	LUAD	460	460
MAPK14	1,975	LUAD	598	598
FYN	1,850	LUAD	48	48
IKBKB	1,714	LUAD	306	306
INSR	1,712	LUAD	43	43
FES	1,708	LUAD	23	23
MET	1,687	LUAD	42	42
NTRK3	1,677	LUAD	35	35
FGR	1,647	LUAD	43	43
ALK	1,638	LUAD	33	33
CSNK1D	1,630	LUAD	234	234
MAPK8	1,611	LUAD	396	396
FLT3	1,584	LUAD	27	27
EPHB3	1,478	LUAD	23	23
GRK2	1,475	LUAD	176	176
RET	1,469	LUAD	27	27
LCK	1,446	LUAD	28	28
AURKB	1,431	LUAD	189	189
GSK3A	1,417	LUAD	284	284
HCK	1,400	LUAD	30	30
MAP2K1	1,377	LUAD	257	257
FER	1,376	LUAD	17	17
PRKCI	1,367	LUAD	452	452
BMX	1,364	LUAD	26	26
EGFR	1,328	LUAD	36	36
CSNK1E	1,321	LUAD	403	403
MAP4K5	1,313	LUAD	419	419
RPS6KA1	1,286	LUAD	280	280
CHUK	1,230	LUAD	255	255
PRKDC	1,218	LUAD	185	185
ATM	1,214	LUAD	74	74
BTK	1,160	LUAD	41	41
PAK1	1,151	LUAD	285	285
LTK	1,139	LUAD	19	19
CSNK1A1	1,138	LUAD	168	168
RAF1	1,128	LUAD	241	241
ROCK1	1,096	LUAD	237	237
PRKCG	1,094	LUAD	161	161
ERN1	1,081	LUAD	530	530
CSNK2A2	1,074	LUAD	302	302
PRKCD	1,069	LUAD	118	118
MAP3K1	1,063	LUAD	316	316
PRKCE	1,061	LUAD	144	144
ABL2	1,050	LUAD	101	101
CAMK2A	1,045	LUAD	200	200
MAP4K4	1,038	LUAD	214	214
HIPK2	1,008	LUAD	225	225
PAK3	987	LUAD	266	266
PTK6	978	LUAD	14	14
MINK1	972	LUAD	189	189
PAK2	926	LUAD	199	199
MAPK7	923	LUAD	165	165
PRKCQ	921	LUAD	131	131
IRAK1	919	LUAD	348	348
EPHA6	913	LUAD	23	23
MAPK13	897	LUAD	269	269
MAPK12	894	LUAD	258	258
CIT	892	LUAD	461	461
CDK5	882	LUAD	227	227
CHEK1	858	LUAD	111	111
STK4	845	LUAD	83	83
CAMKK2	829	LUAD	370	370
CDK7	811	LUAD	161	161
CAMK2D	804	LUAD	212	212
ROCK2	800	LUAD	156	156
MAPK9	794	LUAD	209	209
STK3	785	LUAD	72	72
MAPK11	779	LUAD	171	171
MAP2K4	774	LUAD	113	113
NEK1	773	LUAD	78	78
RPS6KA2	754	LUAD	318	318
MARK4	750	LUAD	155	155
MAP3K9	747	LUAD	63	63
CAMK2G	731	LUAD	192	192
PDK1	724	LUAD	137	137
STK24	718	LUAD	54	54
PRKCZ	717	LUAD	86	86
AKT2	712	LUAD	196	196
NEK6	707	LUAD	61	61
DYRK2	701	LUAD	169	169
TTBK1	701	LUAD	89	89
IKBKE	699	LUAD	114	114
PRKG2	696	LUAD	168	168
CLK1	693	LUAD	204	204
TAOK3	692	LUAD	371	371
SRPK1	685	LUAD	310	310
PRKG1	681	LUAD	126	126
CAMK2B	676	LUAD	148	148
PIM1	676	LUAD	91	91
STK26	674	LUAD	51	51
CDK4	670	LUAD	132	132
PRKD1	658	LUAD	109	109
RPS6KB1	656	LUAD	160	160
PRKACB	653	LUAD	166	166
NEK7	636	LUAD	75	75
NEK4	618	LUAD	45	45
MAPK10	609	LUAD	161	161
STK25	604	LUAD	41	41
TNIK	604	LUAD	32	32
SIK2	595	LUAD	123	123
LIMK1	592	LUAD	114	114
PRKAA2	571	LUAD	123	123
AURKC	570	LUAD	85	85
MAP2K6	569	LUAD	71	71
PLK3	555	LUAD	86	86
MAPKAPK3	552	LUAD	136	136
PRKAA1	530	LUAD	72	72
LYN	530	LUAD	11	11
NLK	527	LUAD	95	95
TAOK2	521	LUAD	32	32
MAP2K2	516	LUAD	81	81
RPS6KA3	516	LUAD	125	125
CDK9	507	LUAD	209	209
PHKG2	506	LUAD	84	84
MAP3K11	505	LUAD	44	44
NIM1K	503	LUAD	87	87
PRKCH	502	LUAD	79	79
MARK1	498	LUAD	116	116
SGK1	496	LUAD	108	108
TBK1	495	LUAD	67	67
NEK9	494	LUAD	59	59
MAPKAPK2	492	LUAD	140	140
RPS6KA5	480	LUAD	136	136
MAP3K10	479	LUAD	44	44
TGFBR2	465	LUAD	74	74
PLK4	462	LUAD	45	45
DAPK1	458	LUAD	58	58
ATR	456	LUAD	32	32
MAP4K2	455	LUAD	33	33
MAP3K20	450	LUAD	43	43
MAP2K7	447	LUAD	62	62
PIM3	445	LUAD	63	63
CDK6	444	LUAD	114	114
MARK2	442	LUAD	98	98
MAPKAPK5	441	LUAD	120	120
MAP3K7	439	LUAD	35	35
MAP2K3	437	LUAD	53	53
STK11	430	LUAD	20	20
MARK3	427	LUAD	116	116
TLK1	418	LUAD	61	61
CAMK4	417	LUAD	93	93
SGK3	417	LUAD	92	92
GRK5	413	LUAD	74	74
EIF2AK2	399	LUAD	87	87
MATK	396	LUAD	48	48
DYRK3	392	LUAD	96	96
IRAK4	391	LUAD	22	22
TSSK1B	381	LUAD	89	89
MTOR	374	LUAD	84	84
DCLK2	373	LUAD	54	54
ACVR1B	366	LUAD	63	63
SIK1	364	LUAD	118	118
CSNK1G2	363	LUAD	61	61
PRKACG	360	LUAD	66	66
AKT3	347	LUAD	94	94
TLK2	343	LUAD	39	39
MKNK2	341	LUAD	70	70
CSNK1G1	327	LUAD	54	54
PRKD3	319	LUAD	74	74
PAK4	314	LUAD	83	83
RPS6KA6	312	LUAD	82	82
TAOK1	309	LUAD	33	33
PTK2	305	LUAD	12	12
MAP2K5	304	LUAD	34	34
SRPK3	295	LUAD	142	142
TSSK2	294	LUAD	63	63
BMPR1B	289	LUAD	46	46
LATS1	288	LUAD	98	98
DYRK4	279	LUAD	109	109
DSTYK	277	LUAD	38	38
LATS2	277	LUAD	61	61
ULK3	272	LUAD	44	44
NEK11	269	LUAD	19	19
GRK7	267	LUAD	58	58
BUB1B	261	LUAD	43	43
DYRK1A	256	LUAD	89	89
TGFBR1	253	LUAD	36	36
WNK3	244	LUAD	32	32
CHEK2	243	LUAD	35	35
PKN1	243	LUAD	46	46
CAMKK1	239	LUAD	8	8
CAMK1	228	LUAD	45	45
ACVR1	225	LUAD	36	36
RPS6KA4	221	LUAD	72	72
PBK	214	LUAD	14	14
CILK1	210	LUAD	57	57
PAK6	209	LUAD	32	32
WNK1	209	LUAD	20	20
CSNK1G3	206	LUAD	33	33
PRKD2	206	LUAD	51	51
NUAK2	205	LUAD	54	54
FAM20C	204	LUAD	70	70
DMPK	201	LUAD	40	40
ACVR2A	200	LUAD	40	40
MYLK2	191	LUAD	47	47
GRK1	189	LUAD	36	36
GRK3	187	LUAD	18	18
MOK	187	LUAD	40	40
ULK1	187	LUAD	30	30
WNK2	186	LUAD	24	24
CAMK1D	174	LUAD	52	52
PAK5	173	LUAD	37	37
MELK	173	LUAD	50	50
SLK	171	LUAD	14	14
PRKX	169	LUAD	60	60
DCLK1	163	LUAD	25	25
RPS6KB2	161	LUAD	38	38
PLK2	157	LUAD	22	22
CLK2	155	LUAD	40	40
MAP3K8	153	LUAD	15	15
HIPK1	150	LUAD	33	33
OXSR1	149	LUAD	11	11
PIM2	147	LUAD	28	28
GRK4	142	LUAD	13	13
SGK2	142	LUAD	49	49
NUAK1	141	LUAD	28	28
CDC42BPB	138	LUAD	30	30
EEF2K	136	LUAD	12	12
MAP3K2	132	LUAD	31	31
CDC42BPA	130	LUAD	26	26
HASPIN	130	LUAD	11	11
STK38L	128	LUAD	21	21
GRK6	121	LUAD	17	17
PDK4	121	LUAD	22	22
STK38	120	LUAD	22	22
EIF2AK3	117	LUAD	16	16
MOS	117	LUAD	13	13
PDPK1	109	LUAD	16	16
DAPK3	107	LUAD	11	11
LRRK2	107	LUAD	20	20
MAP3K3	106	LUAD	29	29
PHKG1	104	LUAD	20	20
STK39	104	LUAD	11	11
CLK3	103	LUAD	47	47
EIF2AK1	102	LUAD	44	44
HIPK4	101	LUAD	40	40
MAPK15	101	LUAD	20	20
PKN2	99	LUAD	29	29
ACVR2B	97	LUAD	19	19
MAP3K5	97	LUAD	4	4
CDK3	96	LUAD	20	20
BRSK2	95	LUAD	24	24
CDC7	93	LUAD	13	13
HIPK3	91	LUAD	42	42
STK16	89	LUAD	14	14
TRPM6	72	LUAD	6	6
BUB1	70	LUAD	5	5
CLK4	70	LUAD	12	12
VRK1	68	LUAD	10	10
STK10	60	LUAD	3	3
BRSK1	59	LUAD	14	14
DYRK1B	58	LUAD	14	14
PASK	58	LUAD	10	10
NEK3	57	LUAD	7	7
BMPR2	55	LUAD	8	8
STK33	54	LUAD	20	20
BMPR1A	53	LUAD	11	11
CDKL5	52	LUAD	17	17
MAK	50	LUAD	27	27
VRK2	50	LUAD	3	3
RIPK2	47	LUAD	5	5
BRAF	46	LUAD	10	10
MAP3K14	45	LUAD	2	2
SRPK2	42	LUAD	16	16
CDK8	39	LUAD	2	2
MYLK	38	LUAD	6	6
CSNK1A1L	37	LUAD	4	4
MAP3K15	37	LUAD	18	18
PNCK	37	LUAD	9	9
BCKDK	36	LUAD	11	11
DAPK2	36	LUAD	5	5
EIF2AK4	35	LUAD	11	11
MKNK1	34	LUAD	5	5
WNK4	34	LUAD	4	4
CDK12	29	LUAD	12	12
UHMK1	25	LUAD	5	5
MAP3K12	22	LUAD	5	5
CDK14	21	LUAD	3	3
CDK17	20	LUAD	12	12
CDK16	19	LUAD	6	6
TRPM7	19	LUAD	1	1
ULK2	19	LUAD	1	1
SMG1	16	LUAD	2	2
RIPK3	15	LUAD	4	4
MAP4K1	14	LUAD	1	1
CDK19	13	LUAD	1	1
CAMK1G	12	LUAD	3	3
MAP3K6	10	LUAD	2	2
PKN3	10	LUAD	4	4
BMP2K	9	LUAD	5	5
CDK18	7	LUAD	1	1
MAP4K3	6	LUAD	1	1
STK17A	5	LUAD	2	2
MAPK1	3,653	PDAC	773	773
PRKCB	3,645	PDAC	286	286
CDK1	3,527	PDAC	511	511
SRC	3,418	PDAC	33	33
PRKCA	3,390	PDAC	238	238
MAPK3	3,253	PDAC	600	600
CSNK2A1	3,097	PDAC	380	380
PLK1	2,941	PDAC	398	398
ABL1	2,437	PDAC	106	106
GSK3B	2,369	PDAC	241	241
PRKACA	2,337	PDAC	369	369
NEK2	2,152	PDAC	141	141
AKT1	2,097	PDAC	300	300
TTK	2,048	PDAC	219	219
AURKA	2,034	PDAC	162	162
CDK2	1,999	PDAC	309	309
MAPK14	1,975	PDAC	451	451
FYN	1,850	PDAC	31	31
IKBKB	1,714	PDAC	210	210
ALK	1,638	PDAC	20	20
CSNK1D	1,630	PDAC	162	162
MAPK8	1,611	PDAC	286	286
GRK2	1,475	PDAC	120	120
RET	1,469	PDAC	13	13
LCK	1,446	PDAC	16	16
AURKB	1,431	PDAC	130	130
GSK3A	1,417	PDAC	202	202
MAP2K1	1,377	PDAC	157	157
PRKCI	1,367	PDAC	331	331
CSNK1E	1,321	PDAC	299	299
MAP4K5	1,313	PDAC	324	324
RPS6KA1	1,286	PDAC	197	197
CHUK	1,230	PDAC	187	187
PRKDC	1,218	PDAC	113	113
ATM	1,214	PDAC	35	35
BTK	1,160	PDAC	33	33
PAK1	1,151	PDAC	204	204
CSNK1A1	1,138	PDAC	118	118
RAF1	1,128	PDAC	159	159
ROCK1	1,096	PDAC	169	169
PRKCG	1,094	PDAC	104	104
ERN1	1,081	PDAC	392	392
CSNK2A2	1,074	PDAC	236	236
PRKCD	1,069	PDAC	92	92
MAP3K1	1,063	PDAC	269	269
PRKCE	1,061	PDAC	107	107
CAMK2A	1,045	PDAC	155	155
MAP4K4	1,038	PDAC	173	173
HIPK2	1,008	PDAC	163	163
PAK3	987	PDAC	190	190
MINK1	972	PDAC	159	159
PAK2	926	PDAC	150	150
MAPK7	923	PDAC	130	130
PRKCQ	921	PDAC	96	96
IRAK1	919	PDAC	257	257
EPHA6	913	PDAC	16	16
JAK2	907	PDAC	14	14
MAPK13	897	PDAC	228	228
MAPK12	894	PDAC	215	215
CIT	892	PDAC	358	358
CDK5	882	PDAC	158	158
CHEK1	858	PDAC	82	82
STK4	845	PDAC	52	52
CAMKK2	829	PDAC	281	281
CDK7	811	PDAC	94	94
CAMK2D	804	PDAC	162	162
ROCK2	800	PDAC	111	111
MAPK9	794	PDAC	162	162
STK3	785	PDAC	54	54
MAPK11	779	PDAC	134	134
MAP2K4	774	PDAC	84	84
NEK1	773	PDAC	56	56
RPS6KA2	754	PDAC	249	249
MARK4	750	PDAC	113	113
MAP3K9	747	PDAC	49	49
CAMK2G	731	PDAC	149	149
PDK1	724	PDAC	89	89
STK24	718	PDAC	34	34
PRKCZ	717	PDAC	66	66
AKT2	712	PDAC	164	164
NEK6	707	PDAC	41	41
DYRK2	701	PDAC	138	138
TTBK1	701	PDAC	71	71
IKBKE	699	PDAC	74	74
PRKG2	696	PDAC	111	111
CLK1	693	PDAC	187	187
TAOK3	692	PDAC	272	272
SRPK1	685	PDAC	248	248
PRKG1	681	PDAC	85	85
CAMK2B	676	PDAC	117	117
PIM1	676	PDAC	67	67
STK26	674	PDAC	36	36
CDK4	670	PDAC	80	80
PRKD1	658	PDAC	78	78
RPS6KB1	656	PDAC	111	111
PRKACB	653	PDAC	125	125
NEK7	636	PDAC	51	51
NEK4	618	PDAC	26	26
MAPK10	609	PDAC	127	127
STK25	604	PDAC	26	26
TNIK	604	PDAC	22	22
SIK2	595	PDAC	87	87
PRKAA2	571	PDAC	85	85
AURKC	570	PDAC	60	60
MAP2K6	569	PDAC	62	62
PLK3	555	PDAC	61	61
MAPKAPK3	552	PDAC	99	99
PRKAA1	530	PDAC	56	56
LYN	530	PDAC	6	6
NLK	527	PDAC	69	69
TAOK2	521	PDAC	26	26
MAP2K2	516	PDAC	55	55
RPS6KA3	516	PDAC	108	108
CDK9	507	PDAC	159	159
PHKG2	506	PDAC	72	72
MAP3K11	505	PDAC	37	37
NIM1K	503	PDAC	62	62
PRKCH	502	PDAC	59	59
MARK1	498	PDAC	83	83
SGK1	496	PDAC	76	76
TBK1	495	PDAC	52	52
NEK9	494	PDAC	38	38
MAPKAPK2	492	PDAC	119	119
RPS6KA5	480	PDAC	112	112
MAP3K10	479	PDAC	33	33
TGFBR2	465	PDAC	43	43
PLK4	462	PDAC	23	23
DAPK1	458	PDAC	38	38
ATR	456	PDAC	21	21
MAP4K2	455	PDAC	28	28
MAP3K20	450	PDAC	31	31
MAP2K7	447	PDAC	53	53
PIM3	445	PDAC	50	50
CDK6	444	PDAC	84	84
MARK2	442	PDAC	80	80
MAPKAPK5	441	PDAC	96	96
MAP3K7	439	PDAC	22	22
MAP2K3	437	PDAC	43	43
STK11	430	PDAC	12	12
MARK3	427	PDAC	90	90
TLK1	418	PDAC	35	35
CAMK4	417	PDAC	67	67
SGK3	417	PDAC	65	65
GRK5	413	PDAC	56	56
EIF2AK2	399	PDAC	63	63
MATK	396	PDAC	44	44
DYRK3	392	PDAC	80	80
IRAK4	391	PDAC	17	17
TSSK1B	381	PDAC	65	65
MTOR	374	PDAC	65	65
DCLK2	373	PDAC	37	37
ACVR1B	366	PDAC	48	48
SIK1	364	PDAC	100	100
CSNK1G2	363	PDAC	40	40
PRKACG	360	PDAC	61	61
AKT3	347	PDAC	84	84
TLK2	343	PDAC	28	28
MKNK2	341	PDAC	50	50
CSNK1G1	327	PDAC	41	41
PRKD3	319	PDAC	54	54
PAK4	314	PDAC	65	65
RPS6KA6	312	PDAC	70	70
TAOK1	309	PDAC	19	19
PTK2	305	PDAC	11	11
MAP2K5	304	PDAC	29	29
SRPK3	295	PDAC	110	110
TSSK2	294	PDAC	59	59
BMPR1B	289	PDAC	32	32
LATS1	288	PDAC	83	83
DYRK4	279	PDAC	90	90
DSTYK	277	PDAC	31	31
LATS2	277	PDAC	44	44
ULK3	272	PDAC	34	34
NEK11	269	PDAC	11	11
GRK7	267	PDAC	39	39
BUB1B	261	PDAC	41	41
DYRK1A	256	PDAC	70	70
TGFBR1	253	PDAC	34	34
WNK3	244	PDAC	21	21
CHEK2	243	PDAC	28	28
PKN1	243	PDAC	40	40
CAMKK1	239	PDAC	10	10
CAMK1	228	PDAC	47	47
ACVR1	225	PDAC	33	33
RPS6KA4	221	PDAC	64	64
PBK	214	PDAC	11	11
CILK1	210	PDAC	44	44
PAK6	209	PDAC	26	26
WNK1	209	PDAC	10	10
CSNK1G3	206	PDAC	32	32
PRKD2	206	PDAC	45	45
NUAK2	205	PDAC	39	39
FAM20C	204	PDAC	63	63
DMPK	201	PDAC	40	40
ACVR2A	200	PDAC	31	31
MYLK2	191	PDAC	32	32
GRK1	189	PDAC	31	31
GRK3	187	PDAC	14	14
MOK	187	PDAC	30	30
ULK1	187	PDAC	21	21
WNK2	186	PDAC	21	21
CAMK1D	174	PDAC	41	41
PAK5	173	PDAC	29	29
MELK	173	PDAC	39	39
SLK	171	PDAC	13	13
PRKX	169	PDAC	50	50
DCLK1	163	PDAC	17	17
RPS6KB2	161	PDAC	31	31
PLK2	157	PDAC	18	18
CLK2	155	PDAC	38	38
MAP3K8	153	PDAC	16	16
HIPK1	150	PDAC	31	31
OXSR1	149	PDAC	9	9
PIM2	147	PDAC	22	22
GRK4	142	PDAC	10	10
SGK2	142	PDAC	38	38
NUAK1	141	PDAC	22	22
CDC42BPB	138	PDAC	24	24
EEF2K	136	PDAC	12	12
MAP3K2	132	PDAC	29	29
CDC42BPA	130	PDAC	19	19
HASPIN	130	PDAC	7	7
STK38L	128	PDAC	22	22
GRK6	121	PDAC	9	9
PDK4	121	PDAC	21	21
STK38	120	PDAC	20	20
EIF2AK3	117	PDAC	16	16
MOS	117	PDAC	9	9
PDPK1	109	PDAC	15	15
DAPK3	107	PDAC	10	10
LRRK2	107	PDAC	12	12
MAP3K3	106	PDAC	25	25
PHKG1	104	PDAC	20	20
STK39	104	PDAC	9	9
CLK3	103	PDAC	32	32
EIF2AK1	102	PDAC	40	40
HIPK4	101	PDAC	27	27
MAPK15	101	PDAC	20	20
PKN2	99	PDAC	24	24
ACVR2B	97	PDAC	13	13
MAP3K5	97	PDAC	5	5
CDK3	96	PDAC	15	15
BRSK2	95	PDAC	22	22
CDC7	93	PDAC	11	11
HIPK3	91	PDAC	37	37
STK16	89	PDAC	11	11
TRPM6	72	PDAC	4	4
BUB1	70	PDAC	6	6
CLK4	70	PDAC	10	10
VRK1	68	PDAC	8	8
STK10	60	PDAC	4	4
BRSK1	59	PDAC	15	15
DYRK1B	58	PDAC	13	13
PASK	58	PDAC	12	12
NEK3	57	PDAC	5	5
BMPR2	55	PDAC	7	7
STK33	54	PDAC	18	18
BMPR1A	53	PDAC	12	12
CDKL5	52	PDAC	20	20
MAK	50	PDAC	23	23
VRK2	50	PDAC	1	1
RIPK2	47	PDAC	7	7
BRAF	46	PDAC	9	9
MAP3K14	45	PDAC	3	3
SRPK2	42	PDAC	12	12
CDK8	39	PDAC	1	1
MYLK	38	PDAC	6	6
CSNK1A1L	37	PDAC	3	3
MAP3K15	37	PDAC	18	18
PNCK	37	PDAC	10	10
BCKDK	36	PDAC	7	7
DAPK2	36	PDAC	4	4
EIF2AK4	35	PDAC	9	9
MKNK1	34	PDAC	3	3
WNK4	34	PDAC	3	3
CDK12	29	PDAC	4	4
UHMK1	25	PDAC	3	3
MAST2	24	PDAC	6	6
MAP3K12	22	PDAC	5	5
CDK14	21	PDAC	3	3
CDK17	20	PDAC	12	12
CDK16	19	PDAC	7	7
SMG1	16	PDAC	1	1
RIPK3	15	PDAC	4	4
CDK19	13	PDAC	1	1
CAMK1G	12	PDAC	2	2
MAP3K6	10	PDAC	2	2
PKN3	10	PDAC	3	3
BMP2K	9	PDAC	3	3
CDK18	7	PDAC	1	1
MAP4K3	6	PDAC	1	1
STK17A	5	PDAC	1	1
MAPK1	3,653	UCEC	1,127	1,127
PRKCB	3,645	UCEC	318	318
CDK1	3,527	UCEC	812	812
SRC	3,418	UCEC	31	31
PRKCA	3,390	UCEC	225	225
MAPK3	3,253	UCEC	887	887
CSNK2A1	3,097	UCEC	665	665
PLK1	2,941	UCEC	587	587
ABL1	2,437	UCEC	110	110
GSK3B	2,369	UCEC	354	354
PRKACA	2,337	UCEC	427	427
YES1	2,161	UCEC	206	206
NEK2	2,152	UCEC	263	263
AKT1	2,097	UCEC	409	409
TTK	2,048	UCEC	404	404
AURKA	2,034	UCEC	298	298
CDK2	1,999	UCEC	473	473
MAPK14	1,975	UCEC	652	652
FYN	1,850	UCEC	30	30
IKBKB	1,714	UCEC	259	259
FES	1,708	UCEC	10	10
ALK	1,638	UCEC	19	19
CSNK1D	1,630	UCEC	260	260
MAPK8	1,611	UCEC	387	387
GRK2	1,475	UCEC	165	165
RET	1,469	UCEC	16	16
LCK	1,446	UCEC	22	22
AURKB	1,431	UCEC	196	196
GSK3A	1,417	UCEC	312	312
HCK	1,400	UCEC	21	21
MAP2K1	1,377	UCEC	242	242
FER	1,376	UCEC	11	11
PRKCI	1,367	UCEC	459	459
EGFR	1,328	UCEC	29	29
CSNK1E	1,321	UCEC	403	403
MAP4K5	1,313	UCEC	407	407
RPS6KA1	1,286	UCEC	289	289
CHUK	1,230	UCEC	221	221
PRKDC	1,218	UCEC	210	210
ATM	1,214	UCEC	88	88
BTK	1,160	UCEC	32	32
PAK1	1,151	UCEC	248	248
CSNK1A1	1,138	UCEC	177	177
RAF1	1,128	UCEC	213	213
FRK	1,119	UCEC	16	16
ROCK1	1,096	UCEC	237	237
PRKCG	1,094	UCEC	136	136
ERN1	1,081	UCEC	529	529
CSNK2A2	1,074	UCEC	322	322
PRKCD	1,069	UCEC	86	86
MAP3K1	1,063	UCEC	302	302
PRKCE	1,061	UCEC	113	113
ABL2	1,050	UCEC	87	87
CAMK2A	1,045	UCEC	165	165
MAP4K4	1,038	UCEC	196	196
HIPK2	1,008	UCEC	221	221
PAK3	987	UCEC	246	246
MINK1	972	UCEC	175	175
PAK2	926	UCEC	181	181
MAPK7	923	UCEC	174	174
PRKCQ	921	UCEC	84	84
IRAK1	919	UCEC	325	325
MAPK13	897	UCEC	276	276
MAPK12	894	UCEC	275	275
CIT	892	UCEC	454	454
CDK5	882	UCEC	220	220
CHEK1	858	UCEC	92	92
STK4	845	UCEC	76	76
CAMKK2	829	UCEC	363	363
CDK7	811	UCEC	204	204
CAMK2D	804	UCEC	185	185
ROCK2	800	UCEC	147	147
MAPK9	794	UCEC	199	199
STK3	785	UCEC	58	58
MAPK11	779	UCEC	184	184
MAP2K4	774	UCEC	123	123
NEK1	773	UCEC	68	68
RPS6KA2	754	UCEC	297	297
MARK4	750	UCEC	146	146
PTK2B	748	UCEC	14	14
MAP3K9	747	UCEC	35	35
CAMK2G	731	UCEC	167	167
PDK1	724	UCEC	145	145
STK24	718	UCEC	31	31
PRKCZ	717	UCEC	60	60
AKT2	712	UCEC	204	204
NEK6	707	UCEC	35	35
DYRK2	701	UCEC	181	181
TTBK1	701	UCEC	62	62
IKBKE	699	UCEC	81	81
PRKG2	696	UCEC	161	161
CLK1	693	UCEC	269	269
TAOK3	692	UCEC	360	360
SRPK1	685	UCEC	327	327
PRKG1	681	UCEC	119	119
CAMK2B	676	UCEC	121	121
PIM1	676	UCEC	79	79
STK26	674	UCEC	35	35
CDK4	670	UCEC	112	112
PRKD1	658	UCEC	117	117
RPS6KB1	656	UCEC	155	155
PRKACB	653	UCEC	147	147
NEK7	636	UCEC	43	43
NEK4	618	UCEC	21	21
MAPK10	609	UCEC	159	159
STK25	604	UCEC	20	20
TNIK	604	UCEC	20	20
SIK2	595	UCEC	102	102
PRKAA2	571	UCEC	135	135
AURKC	570	UCEC	82	82
MAP2K6	569	UCEC	86	86
PLK3	555	UCEC	64	64
MAPKAPK3	552	UCEC	131	131
PRKAA1	530	UCEC	83	83
NLK	527	UCEC	91	91
TAOK2	521	UCEC	13	13
MAP2K2	516	UCEC	81	81
RPS6KA3	516	UCEC	115	115
CDK9	507	UCEC	206	206
PHKG2	506	UCEC	72	72
MAP3K11	505	UCEC	30	30
NIM1K	503	UCEC	75	75
PRKCH	502	UCEC	42	42
MARK1	498	UCEC	101	101
SGK1	496	UCEC	96	96
TBK1	495	UCEC	45	45
NEK9	494	UCEC	36	36
MAPKAPK2	492	UCEC	149	149
RPS6KA5	480	UCEC	127	127
MAP3K10	479	UCEC	25	25
TGFBR2	465	UCEC	84	84
PLK4	462	UCEC	46	46
DAPK1	458	UCEC	70	70
ATR	456	UCEC	44	44
MAP4K2	455	UCEC	17	17
MAP3K20	450	UCEC	22	22
MAP2K7	447	UCEC	76	76
PIM3	445	UCEC	56	56
CDK6	444	UCEC	105	105
MARK2	442	UCEC	92	92
MAPKAPK5	441	UCEC	113	113
MAP3K7	439	UCEC	21	21
MAP2K3	437	UCEC	58	58
STK11	430	UCEC	40	40
MARK3	427	UCEC	107	107
TLK1	418	UCEC	47	47
CAMK4	417	UCEC	95	95
SGK3	417	UCEC	74	74
GRK5	413	UCEC	58	58
EIF2AK2	399	UCEC	73	73
MATK	396	UCEC	48	48
DYRK3	392	UCEC	103	103
IRAK4	391	UCEC	19	19
TSSK1B	381	UCEC	79	79
MTOR	374	UCEC	80	80
DCLK2	373	UCEC	46	46
ACVR1B	366	UCEC	45	45
SIK1	364	UCEC	102	102
CSNK1G2	363	UCEC	70	70
PRKACG	360	UCEC	60	60
AKT3	347	UCEC	94	94
TLK2	343	UCEC	42	42
MKNK2	341	UCEC	60	60
CSNK1G1	327	UCEC	55	55
PRKD3	319	UCEC	60	60
PAK4	314	UCEC	74	74
RPS6KA6	312	UCEC	75	75
TAOK1	309	UCEC	21	21
MAP2K5	304	UCEC	43	43
SRPK3	295	UCEC	157	157
TSSK2	294	UCEC	56	56
BMPR1B	289	UCEC	33	33
LATS1	288	UCEC	87	87
DYRK4	279	UCEC	105	105
DSTYK	277	UCEC	24	24
LATS2	277	UCEC	49	49
ULK3	272	UCEC	24	24
NEK11	269	UCEC	14	14
GRK7	267	UCEC	46	46
BUB1B	261	UCEC	37	37
DYRK1A	256	UCEC	91	91
TGFBR1	253	UCEC	32	32
WNK3	244	UCEC	19	19
CHEK2	243	UCEC	25	25
PKN1	243	UCEC	36	36
CAMKK1	239	UCEC	5	5
CAMK1	228	UCEC	41	41
ACVR1	225	UCEC	31	31
RPS6KA4	221	UCEC	66	66
PBK	214	UCEC	8	8
CILK1	210	UCEC	53	53
PAK6	209	UCEC	31	31
WNK1	209	UCEC	14	14
CSNK1G3	206	UCEC	37	37
PRKD2	206	UCEC	46	46
NUAK2	205	UCEC	40	40
FAM20C	204	UCEC	40	40
DMPK	201	UCEC	42	42
ACVR2A	200	UCEC	32	32
MYLK2	191	UCEC	41	41
GRK1	189	UCEC	25	25
GRK3	187	UCEC	11	11
MOK	187	UCEC	40	40
ULK1	187	UCEC	29	29
CAMK1D	174	UCEC	42	42
PAK5	173	UCEC	35	35
MELK	173	UCEC	41	41
SLK	171	UCEC	6	6
PRKX	169	UCEC	56	56
DCLK1	163	UCEC	20	20
RPS6KB2	161	UCEC	43	43
PLK2	157	UCEC	16	16
CLK2	155	UCEC	58	58
MAP3K8	153	UCEC	9	9
HIPK1	150	UCEC	34	34
OXSR1	149	UCEC	5	5
PIM2	147	UCEC	25	25
GRK4	142	UCEC	6	6
SGK2	142	UCEC	40	40
NUAK1	141	UCEC	24	24
CDC42BPB	138	UCEC	21	21
EEF2K	136	UCEC	9	9
MAP3K2	132	UCEC	32	32
CDC42BPA	130	UCEC	17	17
HASPIN	130	UCEC	9	9
STK38L	128	UCEC	23	23
GRK6	121	UCEC	10	10
PDK4	121	UCEC	25	25
STK38	120	UCEC	22	22
EIF2AK3	117	UCEC	10	10
MOS	117	UCEC	9	9
PDPK1	109	UCEC	7	7
DAPK3	107	UCEC	17	17
LRRK2	107	UCEC	17	17
MAP3K3	106	UCEC	27	27
PHKG1	104	UCEC	11	11
STK39	104	UCEC	7	7
CLK3	103	UCEC	47	47
EIF2AK1	102	UCEC	35	35
HIPK4	101	UCEC	40	40
MAPK15	101	UCEC	16	16
PKN2	99	UCEC	26	26
ACVR2B	97	UCEC	22	22
MAP3K5	97	UCEC	2	2
CDK3	96	UCEC	21	21
BRSK2	95	UCEC	19	19
CDC7	93	UCEC	8	8
HIPK3	91	UCEC	40	40
STK16	89	UCEC	13	13
TRPM6	72	UCEC	2	2
BUB1	70	UCEC	5	5
CLK4	70	UCEC	11	11
VRK1	68	UCEC	6	6
STK10	60	UCEC	3	3
BRSK1	59	UCEC	6	6
DYRK1B	58	UCEC	12	12
PASK	58	UCEC	10	10
NEK3	57	UCEC	5	5
BMPR2	55	UCEC	4	4
STK33	54	UCEC	18	18
BMPR1A	53	UCEC	9	9
CDKL5	52	UCEC	21	21
MAK	50	UCEC	29	29
VRK2	50	UCEC	4	4
RIPK2	47	UCEC	5	5
BRAF	46	UCEC	9	9
MAP3K14	45	UCEC	2	2
SRPK2	42	UCEC	16	16
CDK8	39	UCEC	1	1
MYLK	38	UCEC	8	8
CSNK1A1L	37	UCEC	5	5
MAP3K15	37	UCEC	17	17
PNCK	37	UCEC	7	7
BCKDK	36	UCEC	10	10
DAPK2	36	UCEC	6	6
EIF2AK4	35	UCEC	6	6
MKNK1	34	UCEC	3	3
WNK4	34	UCEC	6	6
PINK1	32	UCEC	1	1
CDK12	29	UCEC	13	13
UHMK1	25	UCEC	2	2
MAP3K12	22	UCEC	4	4
CDK14	21	UCEC	3	3
CDK17	20	UCEC	13	13
CDK16	19	UCEC	7	7
TRPM7	19	UCEC	1	1
ULK2	19	UCEC	1	1
SMG1	16	UCEC	1	1
RIPK3	15	UCEC	4	4
TTBK2	15	UCEC	1	1
MAP4K1	14	UCEC	1	1
CDK19	13	UCEC	1	1
CAMK1G	12	UCEC	1	1
MAP3K6	10	UCEC	2	2
PKN3	10	UCEC	4	4
BMP2K	9	UCEC	5	5
CDK18	7	UCEC	3	3
STK17A	5	UCEC	2	2
SIK3	3	UCEC	1	1
MAPK1	3,653	AML	407	-
PRKCB	3,645	AML	147	-
CDK1	3,527	AML	242	-
PRKCA	3,390	AML	93	-
MAPK3	3,253	AML	305	-
CSNK2A1	3,097	AML	216	-
PLK1	2,941	AML	185	-
GSK3B	2,369	AML	93	-
PRKACA	2,337	AML	210	-
NEK2	2,152	AML	64	-
AKT1	2,097	AML	163	-
TTK	2,048	AML	173	-
AURKA	2,034	AML	95	-
CDK2	1,999	AML	181	-
MAPK14	1,975	AML	326	-
IKBKB	1,714	AML	69	-
CSNK1D	1,630	AML	54	-
MAPK8	1,611	AML	128	-
GRK2	1,475	AML	44	-
AURKB	1,431	AML	73	-
GSK3A	1,417	AML	64	-
MAP2K1	1,377	AML	94	-
PRKCI	1,367	AML	214	-
CSNK1E	1,321	AML	168	-
MAP4K5	1,313	AML	199	-
RPS6KA1	1,286	AML	107	-
CHUK	1,230	AML	65	-
PRKDC	1,218	AML	35	-
ATM	1,214	AML	17	-
PAK1	1,151	AML	92	-
CSNK1A1	1,138	AML	42	-
RAF1	1,128	AML	53	-
ROCK1	1,096	AML	67	-
PRKCG	1,094	AML	44	-
ERN1	1,081	AML	195	-
CSNK2A2	1,074	AML	128	-
PRKCD	1,069	AML	57	-
MAP3K1	1,063	AML	147	-
PRKCE	1,061	AML	41	-
CAMK2A	1,045	AML	67	-
MAP4K4	1,038	AML	92	-
HIPK2	1,008	AML	93	-
PAK3	987	AML	101	-
MINK1	972	AML	91	-
PAK2	926	AML	71	-
MAPK7	923	AML	69	-
PRKCQ	921	AML	42	-
IRAK1	919	AML	133	-
MAPK13	897	AML	109	-
MAPK12	894	AML	115	-
CIT	892	AML	220	-
CDK5	882	AML	39	-
CHEK1	858	AML	42	-
STK4	845	AML	34	-
CAMKK2	829	AML	179	-
CDK7	811	AML	70	-
CAMK2D	804	AML	88	-
ROCK2	800	AML	50	-
MAPK9	794	AML	93	-
STK3	785	AML	28	-
MAPK11	779	AML	72	-
MAP2K4	774	AML	46	-
NEK1	773	AML	16	-
RPS6KA2	754	AML	196	-
MARK4	750	AML	42	-
MAP3K9	747	AML	13	-
CAMK2G	731	AML	68	-
PDK1	724	AML	37	-
STK24	718	AML	14	-
PRKCZ	717	AML	39	-
AKT2	712	AML	91	-
NEK6	707	AML	12	-
DYRK2	701	AML	77	-
TTBK1	701	AML	17	-
IKBKE	699	AML	22	-
PRKG2	696	AML	53	-
CLK1	693	AML	181	-
TAOK3	692	AML	165	-
SRPK1	685	AML	170	-
PRKG1	681	AML	30	-
CAMK2B	676	AML	40	-
PIM1	676	AML	42	-
STK26	674	AML	19	-
CDK4	670	AML	44	-
PRKD1	658	AML	38	-
RPS6KB1	656	AML	66	-
PRKACB	653	AML	63	-
NEK7	636	AML	16	-
NEK4	618	AML	13	-
MAPK10	609	AML	55	-
STK25	604	AML	8	-
TNIK	604	AML	4	-
SIK2	595	AML	36	-
PRKAA2	571	AML	40	-
AURKC	570	AML	32	-
MAP2K6	569	AML	37	-
PLK3	555	AML	25	-
MAPKAPK3	552	AML	54	-
PRKAA1	530	AML	23	-
NLK	527	AML	31	-
TAOK2	521	AML	10	-
MAP2K2	516	AML	44	-
RPS6KA3	516	AML	68	-
CDK9	507	AML	108	-
PHKG2	506	AML	46	-
MAP3K11	505	AML	21	-
NIM1K	503	AML	22	-
PRKCH	502	AML	30	-
MARK1	498	AML	24	-
SGK1	496	AML	45	-
TBK1	495	AML	13	-
NEK9	494	AML	16	-
MAPKAPK2	492	AML	75	-
RPS6KA5	480	AML	62	-
MAP3K10	479	AML	11	-
TGFBR2	465	AML	16	-
PLK4	462	AML	13	-
DAPK1	458	AML	30	-
ATR	456	AML	5	-
MAP4K2	455	AML	10	-
MAP3K20	450	AML	13	-
MAP2K7	447	AML	40	-
PIM3	445	AML	33	-
CDK6	444	AML	81	-
MARK2	442	AML	28	-
MAPKAPK5	441	AML	48	-
MAP3K7	439	AML	18	-
MAP2K3	437	AML	32	-
STK11	430	AML	6	-
MARK3	427	AML	27	-
TLK1	418	AML	20	-
CAMK4	417	AML	36	-
SGK3	417	AML	39	-
GRK5	413	AML	29	-
EIF2AK2	399	AML	31	-
MATK	396	AML	33	-
DYRK3	392	AML	47	-
IRAK4	391	AML	8	-
TSSK1B	381	AML	28	-
MTOR	374	AML	52	-
DCLK2	373	AML	25	-
ACVR1B	366	AML	17	-
SIK1	364	AML	58	-
CSNK1G2	363	AML	22	-
AKT3	347	AML	57	-
TLK2	343	AML	13	-
MKNK2	341	AML	24	-
CSNK1G1	327	AML	18	-
PRKD3	319	AML	25	-
PAK4	314	AML	37	-
RPS6KA6	312	AML	53	-
TAOK1	309	AML	20	-
MAP2K5	304	AML	12	-
SRPK3	295	AML	94	-
TSSK2	294	AML	27	-
BMPR1B	289	AML	17	-
LATS1	288	AML	55	-
DYRK4	279	AML	67	-
DSTYK	277	AML	11	-
LATS2	277	AML	22	-
NEK11	269	AML	8	-
GRK7	267	AML	23	-
BUB1B	261	AML	17	-
DYRK1A	256	AML	52	-
TGFBR1	253	AML	16	-
WNK3	244	AML	9	-
CHEK2	243	AML	18	-
PKN1	243	AML	19	-
CAMKK1	239	AML	4	-
CAMK1	228	AML	18	-
ACVR1	225	AML	18	-
RPS6KA4	221	AML	47	-
PBK	214	AML	4	-
CILK1	210	AML	23	-
PAK6	209	AML	12	-
WNK1	209	AML	5	-
CSNK1G3	206	AML	10	-
PRKD2	206	AML	18	-
NUAK2	205	AML	13	-
FAM20C	204	AML	3	-
DMPK	201	AML	11	-
ACVR2A	200	AML	23	-
MYLK2	191	AML	20	-
GRK1	189	AML	19	-
GRK3	187	AML	5	-
MOK	187	AML	17	-
ULK1	187	AML	11	-
CAMK1D	174	AML	18	-
PAK5	173	AML	19	-
SLK	171	AML	6	-
PRKX	169	AML	32	-
DCLK1	163	AML	13	-
RPS6KB2	161	AML	23	-
PLK2	157	AML	6	-
CLK2	155	AML	35	-
MAP3K8	153	AML	6	-
HIPK1	150	AML	31	-
OXSR1	149	AML	4	-
PIM2	147	AML	18	-
GRK4	142	AML	4	-
SGK2	142	AML	34	-
NUAK1	141	AML	9	-
CDC42BPB	138	AML	19	-
EEF2K	136	AML	6	-
MAP3K2	132	AML	28	-
CDC42BPA	130	AML	12	-
HASPIN	130	AML	5	-
GRK6	121	AML	4	-
PDK4	121	AML	6	-
EIF2AK3	117	AML	2	-
MOS	117	AML	5	-
PDPK1	109	AML	5	-
DAPK3	107	AML	8	-
LRRK2	107	AML	18	-
MAP3K3	106	AML	18	-
PHKG1	104	AML	13	-
STK39	104	AML	4	-
CLK3	103	AML	33	-
EIF2AK1	102	AML	22	-
HIPK4	101	AML	20	-
MAPK15	101	AML	15	-
ACVR2B	97	AML	9	-
MAP3K5	97	AML	6	-
CDK3	96	AML	6	-
BRSK2	95	AML	12	-
CDC7	93	AML	8	-
HIPK3	91	AML	23	-
STK16	89	AML	11	-
TRPM6	72	AML	2	-
BUB1	70	AML	4	-
CLK4	70	AML	8	-
VRK1	68	AML	1	-
STK10	60	AML	4	-
BRSK1	59	AML	4	-
DYRK1B	58	AML	7	-
PASK	58	AML	6	-
NEK3	57	AML	2	-
BMPR2	55	AML	3	-
STK33	54	AML	20	-
BMPR1A	53	AML	11	-
CDKL5	52	AML	17	-
MAK	50	AML	5	-
VRK2	50	AML	1	-
RIPK2	47	AML	2	-
BRAF	46	AML	7	-
MAP3K14	45	AML	3	-
SRPK2	42	AML	16	-
MYLK	38	AML	10	-
CSNK1A1L	37	AML	1	-
MAP3K15	37	AML	15	-
PNCK	37	AML	5	-
BCKDK	36	AML	6	-
DAPK2	36	AML	3	-
EIF2AK4	35	AML	3	-
MKNK1	34	AML	2	-
WNK4	34	AML	3	-
CDK12	29	AML	4	-
UHMK1	25	AML	3	-
MAP3K12	22	AML	5	-
CDK14	21	AML	1	-
CDK17	20	AML	6	-
CDK16	19	AML	4	-
ULK2	19	AML	1	-
RIPK3	15	AML	3	-
MAP4K1	14	AML	1	-
CAMK1G	12	AML	1	-
MAP3K6	10	AML	4	-
PKN3	10	AML	5	-
BMP2K	9	AML	2	-
CDK18	7	AML	3	-
STK17A	5	AML	1	-
MASTL	4	AML	1	-
MAPK1	3,653	BC	1,290	-
PRKCB	3,645	BC	536	-
CDK1	3,527	BC	1,137	-
SRC	3,418	BC	59	-
PRKCA	3,390	BC	413	-
MAPK3	3,253	BC	1,094	-
CSNK2A1	3,097	BC	764	-
PLK1	2,941	BC	798	-
ABL1	2,437	BC	158	-
GSK3B	2,369	BC	496	-
PRKACA	2,337	BC	569	-
YES1	2,161	BC	233	-
NEK2	2,152	BC	459	-
AKT1	2,097	BC	529	-
TTK	2,048	BC	519	-
AURKA	2,034	BC	461	-
CDK2	1,999	BC	671	-
MAPK14	1,975	BC	778	-
FYN	1,850	BC	41	-
IKBKB	1,714	BC	389	-
INSR	1,712	BC	52	-
NTRK3	1,677	BC	51	-
FGR	1,647	BC	40	-
ALK	1,638	BC	47	-
CSNK1D	1,630	BC	378	-
MAPK8	1,611	BC	477	-
GRK2	1,475	BC	236	-
RET	1,469	BC	38	-
LCK	1,446	BC	40	-
AURKB	1,431	BC	271	-
GSK3A	1,417	BC	429	-
HCK	1,400	BC	26	-
MAP2K1	1,377	BC	340	-
PRKCI	1,367	BC	589	-
BMX	1,364	BC	24	-
EGFR	1,328	BC	40	-
CSNK1E	1,321	BC	554	-
MAP4K5	1,313	BC	530	-
RPS6KA1	1,286	BC	363	-
TEC	1,237	BC	21	-
CHUK	1,230	BC	335	-
PRKDC	1,218	BC	284	-
ATM	1,214	BC	116	-
BTK	1,160	BC	47	-
PAK1	1,151	BC	351	-
LTK	1,139	BC	19	-
CSNK1A1	1,138	BC	274	-
RAF1	1,128	BC	327	-
ROCK1	1,096	BC	309	-
PRKCG	1,094	BC	229	-
ERN1	1,081	BC	661	-
CSNK2A2	1,074	BC	379	-
PRKCD	1,069	BC	176	-
MAP3K1	1,063	BC	411	-
PRKCE	1,061	BC	192	-
ABL2	1,050	BC	117	-
CAMK2A	1,045	BC	247	-
MAP4K4	1,038	BC	271	-
JAK3	1,035	BC	21	-
HIPK2	1,008	BC	299	-
PAK3	987	BC	352	-
MINK1	972	BC	246	-
PAK2	926	BC	272	-
MAPK7	923	BC	234	-
PRKCQ	921	BC	199	-
IRAK1	919	BC	433	-
JAK2	907	BC	20	-
MAPK13	897	BC	346	-
MAPK12	894	BC	348	-
CIT	892	BC	571	-
CDK5	882	BC	280	-
CHEK1	858	BC	144	-
STK4	845	BC	117	-
CAMKK2	829	BC	464	-
CDK7	811	BC	241	-
CAMK2D	804	BC	270	-
ROCK2	800	BC	195	-
MAPK9	794	BC	275	-
STK3	785	BC	89	-
MAPK11	779	BC	213	-
MAP2K4	774	BC	160	-
NEK1	773	BC	107	-
RPS6KA2	754	BC	386	-
MARK4	750	BC	230	-
PTK2B	748	BC	19	-
MAP3K9	747	BC	81	-
CAMK2G	731	BC	249	-
PDK1	724	BC	193	-
STK24	718	BC	74	-
PRKCZ	717	BC	124	-
AKT2	712	BC	251	-
NEK6	707	BC	83	-
DYRK2	701	BC	216	-
TTBK1	701	BC	126	-
IKBKE	699	BC	158	-
PRKG2	696	BC	204	-
CLK1	693	BC	272	-
TAOK3	692	BC	447	-
SRPK1	685	BC	404	-
PRKG1	681	BC	161	-
CAMK2B	676	BC	174	-
PIM1	676	BC	116	-
STK26	674	BC	79	-
CDK4	670	BC	179	-
PRKD1	658	BC	159	-
RPS6KB1	656	BC	199	-
PRKACB	653	BC	198	-
NEK7	636	BC	99	-
NEK4	618	BC	58	-
MAPK10	609	BC	201	-
STK25	604	BC	55	-
TNIK	604	BC	51	-
SIK2	595	BC	166	-
LIMK1	592	BC	132	-
PRKAA2	571	BC	165	-
AURKC	570	BC	143	-
MAP2K6	569	BC	99	-
PLK3	555	BC	114	-
MAPKAPK3	552	BC	173	-
PRKAA1	530	BC	96	-
LYN	530	BC	12	-
NLK	527	BC	127	-
TAOK2	521	BC	55	-
MAP2K2	516	BC	109	-
RPS6KA3	516	BC	146	-
CDK9	507	BC	278	-
PHKG2	506	BC	123	-
MAP3K11	505	BC	70	-
NIM1K	503	BC	113	-
PRKCH	502	BC	129	-
MARK1	498	BC	154	-
SGK1	496	BC	140	-
TBK1	495	BC	94	-
NEK9	494	BC	67	-
MAPKAPK2	492	BC	182	-
RPS6KA5	480	BC	175	-
MAP3K10	479	BC	62	-
TGFBR2	465	BC	87	-
PLK4	462	BC	81	-
DAPK1	458	BC	74	-
ATR	456	BC	49	-
MAP4K2	455	BC	41	-
MAP3K20	450	BC	59	-
MAP2K7	447	BC	112	-
PIM3	445	BC	85	-
CDK6	444	BC	157	-
MARK2	442	BC	133	-
MAPKAPK5	441	BC	155	-
MAP3K7	439	BC	36	-
MAP2K3	437	BC	75	-
STK11	430	BC	43	-
MARK3	427	BC	153	-
TLK1	418	BC	82	-
CAMK4	417	BC	118	-
SGK3	417	BC	113	-
GRK5	413	BC	90	-
EIF2AK2	399	BC	111	-
MATK	396	BC	58	-
DYRK3	392	BC	124	-
IRAK4	391	BC	36	-
TSSK1B	381	BC	111	-
MTOR	374	BC	102	-
DCLK2	373	BC	73	-
ACVR1B	366	BC	83	-
SIK1	364	BC	145	-
CSNK1G2	363	BC	87	-
PRKACG	360	BC	92	-
AKT3	347	BC	127	-
TLK2	343	BC	65	-
MKNK2	341	BC	92	-
CSNK1G1	327	BC	81	-
PRKD3	319	BC	90	-
PAK4	314	BC	117	-
RPS6KA6	312	BC	107	-
TAOK1	309	BC	56	-
PTK2	305	BC	18	-
MAP2K5	304	BC	62	-
SRPK3	295	BC	184	-
TSSK2	294	BC	85	-
BMPR1B	289	BC	56	-
LATS1	288	BC	121	-
DYRK4	279	BC	123	-
DSTYK	277	BC	44	-
LATS2	277	BC	74	-
ULK3	272	BC	52	-
NEK11	269	BC	23	-
GRK7	267	BC	70	-
BUB1B	261	BC	62	-
DYRK1A	256	BC	115	-
TGFBR1	253	BC	50	-
WNK3	244	BC	46	-
CHEK2	243	BC	40	-
PKN1	243	BC	63	-
CAMKK1	239	BC	15	-
CAMK1	228	BC	61	-
ACVR1	225	BC	48	-
RPS6KA4	221	BC	95	-
PBK	214	BC	20	-
CILK1	210	BC	66	-
PAK6	209	BC	56	-
WNK1	209	BC	25	-
CSNK1G3	206	BC	51	-
PRKD2	206	BC	70	-
NUAK2	205	BC	70	-
FAM20C	204	BC	80	-
DMPK	201	BC	63	-
ACVR2A	200	BC	49	-
MYLK2	191	BC	52	-
GRK1	189	BC	39	-
GRK3	187	BC	23	-
MOK	187	BC	48	-
ULK1	187	BC	38	-
WNK2	186	BC	29	-
CAMK1D	174	BC	60	-
PAK5	173	BC	58	-
MELK	173	BC	59	-
SLK	171	BC	26	-
PRKX	169	BC	81	-
DCLK1	163	BC	37	-
RPS6KB2	161	BC	51	-
PLK2	157	BC	34	-
CLK2	155	BC	52	-
MAP3K8	153	BC	26	-
HIPK1	150	BC	48	-
OXSR1	149	BC	15	-
PIM2	147	BC	37	-
GRK4	142	BC	14	-
SGK2	142	BC	66	-
NUAK1	141	BC	38	-
TESK1	139	BC	9	-
CDC42BPB	138	BC	45	-
EEF2K	136	BC	15	-
MAP3K2	132	BC	50	-
CDC42BPA	130	BC	45	-
HASPIN	130	BC	15	-
STK38L	128	BC	34	-
GRK6	121	BC	21	-
PDK4	121	BC	29	-
STK38	120	BC	41	-
EIF2AK3	117	BC	22	-
MOS	117	BC	24	-
PDPK1	109	BC	24	-
DAPK3	107	BC	16	-
LRRK2	107	BC	21	-
MAP3K3	106	BC	35	-
PHKG1	104	BC	27	-
STK39	104	BC	15	-
CLK3	103	BC	56	-
EIF2AK1	102	BC	48	-
HIPK4	101	BC	49	-
MAPK15	101	BC	26	-
PKN2	99	BC	39	-
ACVR2B	97	BC	26	-
MAP3K5	97	BC	7	-
CDK3	96	BC	28	-
BRSK2	95	BC	29	-
CDC7	93	BC	16	-
HIPK3	91	BC	60	-
STK16	89	BC	17	-
TRPM6	72	BC	10	-
BUB1	70	BC	9	-
CLK4	70	BC	24	-
VRK1	68	BC	12	-
STK10	60	BC	7	-
BRSK1	59	BC	18	-
DYRK1B	58	BC	21	-
PASK	58	BC	14	-
NEK3	57	BC	6	-
BMPR2	55	BC	12	-
STK33	54	BC	22	-
BMPR1A	53	BC	16	-
CDKL5	52	BC	29	-
MAK	50	BC	34	-
VRK2	50	BC	6	-
RIPK2	47	BC	10	-
BRAF	46	BC	15	-
MAP3K14	45	BC	2	-
SRPK2	42	BC	19	-
CDK8	39	BC	2	-
MYLK	38	BC	6	-
CSNK1A1L	37	BC	8	-
MAP3K15	37	BC	25	-
PNCK	37	BC	12	-
BCKDK	36	BC	13	-
DAPK2	36	BC	5	-
EIF2AK4	35	BC	11	-
MKNK1	34	BC	5	-
WNK4	34	BC	8	-
CDK12	29	BC	15	-
UHMK1	25	BC	3	-
MAP3K12	22	BC	11	-
CDK14	21	BC	4	-
CDK17	20	BC	17	-
CDK16	19	BC	8	-
TRPM7	19	BC	1	-
ULK2	19	BC	4	-
SMG1	16	BC	1	-
RIPK3	15	BC	6	-
MAP4K1	14	BC	1	-
CDK19	13	BC	1	-
CAMK1G	12	BC	2	-
MAP3K6	10	BC	4	-
PKN3	10	BC	4	-
BMP2K	9	BC	6	-
CDK18	7	BC	3	-
MAP4K3	6	BC	1	-
STK17A	5	BC	2	-
MASTL	4	BC	1	-
SIK3	3	BC	2	-
MAPK1	3,653	iCCA	928	-
PRKCB	3,645	iCCA	369	-
CDK1	3,527	iCCA	607	-
SRC	3,418	iCCA	33	-
PRKCA	3,390	iCCA	298	-
MAPK3	3,253	iCCA	750	-
CSNK2A1	3,097	iCCA	443	-
PLK1	2,941	iCCA	505	-
ABL1	2,437	iCCA	113	-
GSK3B	2,369	iCCA	334	-
PRKACA	2,337	iCCA	434	-
NEK2	2,152	iCCA	196	-
AKT1	2,097	iCCA	413	-
TTK	2,048	iCCA	303	-
AURKA	2,034	iCCA	221	-
CDK2	1,999	iCCA	397	-
MAPK14	1,975	iCCA	620	-
FYN	1,850	iCCA	40	-
IKBKB	1,714	iCCA	285	-
INSR	1,712	iCCA	33	-
NTRK3	1,677	iCCA	35	-
ALK	1,638	iCCA	30	-
CSNK1D	1,630	iCCA	249	-
MAPK8	1,611	iCCA	365	-
EPHB3	1,478	iCCA	15	-
GRK2	1,475	iCCA	162	-
RET	1,469	iCCA	17	-
AURKB	1,431	iCCA	171	-
GSK3A	1,417	iCCA	290	-
MAP2K1	1,377	iCCA	234	-
FER	1,376	iCCA	13	-
PRKCI	1,367	iCCA	440	-
CSNK1E	1,321	iCCA	387	-
MAP4K5	1,313	iCCA	419	-
RPS6KA1	1,286	iCCA	281	-
CHUK	1,230	iCCA	228	-
PRKDC	1,218	iCCA	123	-
ATM	1,214	iCCA	65	-
BTK	1,160	iCCA	32	-
PAK1	1,151	iCCA	265	-
CSNK1A1	1,138	iCCA	143	-
RAF1	1,128	iCCA	205	-
ROCK1	1,096	iCCA	230	-
PRKCG	1,094	iCCA	165	-
ERN1	1,081	iCCA	504	-
CSNK2A2	1,074	iCCA	269	-
PRKCD	1,069	iCCA	121	-
MAP3K1	1,063	iCCA	343	-
PRKCE	1,061	iCCA	121	-
CAMK2A	1,045	iCCA	195	-
MAP4K4	1,038	iCCA	229	-
JAK3	1,035	iCCA	17	-
HIPK2	1,008	iCCA	203	-
PAK3	987	iCCA	250	-
MINK1	972	iCCA	200	-
PAK2	926	iCCA	207	-
MAPK7	923	iCCA	166	-
PRKCQ	921	iCCA	133	-
IRAK1	919	iCCA	331	-
MAPK13	897	iCCA	259	-
MAPK12	894	iCCA	275	-
CIT	892	iCCA	448	-
CDK5	882	iCCA	203	-
CHEK1	858	iCCA	99	-
STK4	845	iCCA	94	-
CAMKK2	829	iCCA	362	-
CDK7	811	iCCA	141	-
CAMK2D	804	iCCA	207	-
ROCK2	800	iCCA	142	-
MAPK9	794	iCCA	194	-
STK3	785	iCCA	80	-
MAPK11	779	iCCA	171	-
MAP2K4	774	iCCA	107	-
NEK1	773	iCCA	80	-
RPS6KA2	754	iCCA	325	-
MARK4	750	iCCA	154	-
MAP3K9	747	iCCA	61	-
CAMK2G	731	iCCA	193	-
PDK1	724	iCCA	127	-
STK24	718	iCCA	59	-
PRKCZ	717	iCCA	91	-
AKT2	712	iCCA	205	-
NEK6	707	iCCA	62	-
DYRK2	701	iCCA	194	-
TTBK1	701	iCCA	83	-
IKBKE	699	iCCA	95	-
PRKG2	696	iCCA	152	-
CLK1	693	iCCA	278	-
TAOK3	692	iCCA	344	-
SRPK1	685	iCCA	332	-
PRKG1	681	iCCA	119	-
CAMK2B	676	iCCA	128	-
PIM1	676	iCCA	96	-
STK26	674	iCCA	56	-
CDK4	670	iCCA	113	-
PRKD1	658	iCCA	108	-
RPS6KB1	656	iCCA	158	-
PRKACB	653	iCCA	156	-
NEK7	636	iCCA	71	-
NEK4	618	iCCA	40	-
MAPK10	609	iCCA	157	-
STK25	604	iCCA	44	-
TNIK	604	iCCA	36	-
SIK2	595	iCCA	126	-
PRKAA2	571	iCCA	112	-
AURKC	570	iCCA	81	-
MAP2K6	569	iCCA	79	-
PLK3	555	iCCA	93	-
MAPKAPK3	552	iCCA	125	-
PRKAA1	530	iCCA	72	-
NLK	527	iCCA	92	-
TAOK2	521	iCCA	42	-
MAP2K2	516	iCCA	82	-
RPS6KA3	516	iCCA	127	-
CDK9	507	iCCA	218	-
PHKG2	506	iCCA	99	-
MAP3K11	505	iCCA	49	-
NIM1K	503	iCCA	84	-
PRKCH	502	iCCA	84	-
MARK1	498	iCCA	103	-
SGK1	496	iCCA	104	-
TBK1	495	iCCA	70	-
NEK9	494	iCCA	56	-
MAPKAPK2	492	iCCA	151	-
RPS6KA5	480	iCCA	129	-
MAP3K10	479	iCCA	48	-
TGFBR2	465	iCCA	63	-
PLK4	462	iCCA	35	-
DAPK1	458	iCCA	54	-
ATR	456	iCCA	30	-
MAP4K2	455	iCCA	35	-
MAP3K20	450	iCCA	46	-
MAP2K7	447	iCCA	79	-
PIM3	445	iCCA	64	-
CDK6	444	iCCA	112	-
MARK2	442	iCCA	111	-
MAPKAPK5	441	iCCA	120	-
MAP3K7	439	iCCA	41	-
MAP2K3	437	iCCA	61	-
STK11	430	iCCA	29	-
MARK3	427	iCCA	114	-
TLK1	418	iCCA	58	-
CAMK4	417	iCCA	83	-
SGK3	417	iCCA	99	-
GRK5	413	iCCA	74	-
EIF2AK2	399	iCCA	62	-
MATK	396	iCCA	54	-
DYRK3	392	iCCA	116	-
IRAK4	391	iCCA	24	-
TSSK1B	381	iCCA	83	-
MTOR	374	iCCA	78	-
DCLK2	373	iCCA	61	-
ACVR1B	366	iCCA	56	-
SIK1	364	iCCA	123	-
CSNK1G2	363	iCCA	66	-
PRKACG	360	iCCA	67	-
AKT3	347	iCCA	108	-
TLK2	343	iCCA	38	-
MKNK2	341	iCCA	64	-
CSNK1G1	327	iCCA	46	-
PRKD3	319	iCCA	62	-
PAK4	314	iCCA	89	-
RPS6KA6	312	iCCA	88	-
TAOK1	309	iCCA	37	-
PTK2	305	iCCA	13	-
MAP2K5	304	iCCA	42	-
SRPK3	295	iCCA	152	-
TSSK2	294	iCCA	76	-
BMPR1B	289	iCCA	46	-
LATS1	288	iCCA	112	-
DYRK4	279	iCCA	120	-
DSTYK	277	iCCA	35	-
LATS2	277	iCCA	61	-
ULK3	272	iCCA	46	-
NEK11	269	iCCA	20	-
GRK7	267	iCCA	59	-
BUB1B	261	iCCA	47	-
DYRK1A	256	iCCA	96	-
TGFBR1	253	iCCA	42	-
WNK3	244	iCCA	28	-
CHEK2	243	iCCA	30	-
PKN1	243	iCCA	51	-
CAMKK1	239	iCCA	13	-
CAMK1	228	iCCA	36	-
ACVR1	225	iCCA	43	-
RPS6KA4	221	iCCA	81	-
PBK	214	iCCA	14	-
CILK1	210	iCCA	55	-
PAK6	209	iCCA	39	-
WNK1	209	iCCA	21	-
CSNK1G3	206	iCCA	44	-
PRKD2	206	iCCA	43	-
NUAK2	205	iCCA	56	-
FAM20C	204	iCCA	73	-
DMPK	201	iCCA	40	-
ACVR2A	200	iCCA	41	-
MYLK2	191	iCCA	41	-
GRK1	189	iCCA	41	-
GRK3	187	iCCA	17	-
MOK	187	iCCA	40	-
ULK1	187	iCCA	33	-
WNK2	186	iCCA	27	-
CAMK1D	174	iCCA	55	-
PAK5	173	iCCA	44	-
MELK	173	iCCA	48	-
SLK	171	iCCA	18	-
PRKX	169	iCCA	68	-
DCLK1	163	iCCA	25	-
RPS6KB2	161	iCCA	45	-
PLK2	157	iCCA	24	-
CLK2	155	iCCA	55	-
MAP3K8	153	iCCA	19	-
HIPK1	150	iCCA	47	-
OXSR1	149	iCCA	12	-
PIM2	147	iCCA	31	-
GRK4	142	iCCA	16	-
SGK2	142	iCCA	52	-
NUAK1	141	iCCA	32	-
CDC42BPB	138	iCCA	31	-
EEF2K	136	iCCA	15	-
PDK2	136	iCCA	27	-
MAP3K2	132	iCCA	41	-
CDC42BPA	130	iCCA	32	-
HASPIN	130	iCCA	13	-
STK38L	128	iCCA	32	-
GRK6	121	iCCA	19	-
PDK4	121	iCCA	19	-
STK38	120	iCCA	29	-
EIF2AK3	117	iCCA	16	-
MOS	117	iCCA	14	-
PDPK1	109	iCCA	15	-
DAPK3	107	iCCA	10	-
LRRK2	107	iCCA	18	-
MAP3K3	106	iCCA	31	-
PHKG1	104	iCCA	22	-
STK39	104	iCCA	11	-
CLK3	103	iCCA	50	-
EIF2AK1	102	iCCA	41	-
HIPK4	101	iCCA	35	-
MAPK15	101	iCCA	27	-
PKN2	99	iCCA	29	-
ACVR2B	97	iCCA	12	-
MAP3K5	97	iCCA	5	-
CDK3	96	iCCA	15	-
BRSK2	95	iCCA	26	-
CDC7	93	iCCA	17	-
HIPK3	91	iCCA	53	-
STK16	89	iCCA	14	-
TRPM6	72	iCCA	10	-
BUB1	70	iCCA	6	-
CLK4	70	iCCA	8	-
VRK1	68	iCCA	9	-
STK10	60	iCCA	7	-
BRSK1	59	iCCA	16	-
DYRK1B	58	iCCA	13	-
PASK	58	iCCA	9	-
NEK3	57	iCCA	3	-
BMPR2	55	iCCA	10	-
STK33	54	iCCA	25	-
BMPR1A	53	iCCA	17	-
CDKL5	52	iCCA	23	-
MAK	50	iCCA	28	-
VRK2	50	iCCA	3	-
RIPK2	47	iCCA	6	-
BRAF	46	iCCA	10	-
MAP3K14	45	iCCA	5	-
SRPK2	42	iCCA	19	-
CDK8	39	iCCA	1	-
MYLK	38	iCCA	6	-
CSNK1A1L	37	iCCA	6	-
MAP3K15	37	iCCA	17	-
PNCK	37	iCCA	9	-
BCKDK	36	iCCA	7	-
DAPK2	36	iCCA	4	-
EIF2AK4	35	iCCA	9	-
MKNK1	34	iCCA	5	-
WNK4	34	iCCA	9	-
PINK1	32	iCCA	1	-
CDK12	29	iCCA	14	-
UHMK1	25	iCCA	4	-
MAST2	24	iCCA	9	-
MAP3K12	22	iCCA	5	-
CDK14	21	iCCA	2	-
CDK17	20	iCCA	15	-
CDK16	19	iCCA	7	-
ULK2	19	iCCA	1	-
SMG1	16	iCCA	1	-
RIPK3	15	iCCA	4	-
CAMK1G	12	iCCA	1	-
MAP3K6	10	iCCA	2	-
PKN3	10	iCCA	6	-
BMP2K	9	iCCA	5	-
AAK1	8	iCCA	1	-
CDK18	7	iCCA	2	-
MAP4K3	6	iCCA	1	-
STK17A	5	iCCA	2	-
MASTL	4	iCCA	1	-
MAPK1	3,653	PBC	344	-
CDK1	3,527	PBC	174	-
PRKCA	3,390	PBC	54	-
MAPK3	3,253	PBC	231	-
CSNK2A1	3,097	PBC	217	-
PLK1	2,941	PBC	163	-
GSK3B	2,369	PBC	106	-
PRKACA	2,337	PBC	140	-
NEK2	2,152	PBC	31	-
AKT1	2,097	PBC	96	-
TTK	2,048	PBC	88	-
AURKA	2,034	PBC	40	-
CDK2	1,999	PBC	91	-
MAPK14	1,975	PBC	225	-
IKBKB	1,714	PBC	68	-
CSNK1D	1,630	PBC	101	-
MAPK8	1,611	PBC	135	-
GRK2	1,475	PBC	63	-
AURKB	1,431	PBC	39	-
GSK3A	1,417	PBC	102	-
MAP2K1	1,377	PBC	57	-
PRKCI	1,367	PBC	140	-
CSNK1E	1,321	PBC	105	-
MAP4K5	1,313	PBC	129	-
RPS6KA1	1,286	PBC	75	-
CHUK	1,230	PBC	50	-
PRKDC	1,218	PBC	50	-
ATM	1,214	PBC	11	-
PAK1	1,151	PBC	75	-
CSNK1A1	1,138	PBC	52	-
RAF1	1,128	PBC	49	-
ROCK1	1,096	PBC	61	-
PRKCG	1,094	PBC	39	-
ERN1	1,081	PBC	168	-
CSNK2A2	1,074	PBC	174	-
PRKCD	1,069	PBC	28	-
MAP3K1	1,063	PBC	90	-
PRKCE	1,061	PBC	30	-
CAMK2A	1,045	PBC	69	-
MAP4K4	1,038	PBC	63	-
HIPK2	1,008	PBC	54	-
PAK3	987	PBC	58	-
MINK1	972	PBC	55	-
PAK2	926	PBC	46	-
MAPK7	923	PBC	54	-
IRAK1	919	PBC	79	-
MAPK13	897	PBC	92	-
MAPK12	894	PBC	111	-
CIT	892	PBC	109	-
CDK5	882	PBC	97	-
CHEK1	858	PBC	29	-
STK4	845	PBC	22	-
CAMKK2	829	PBC	90	-
CDK7	811	PBC	34	-
CAMK2D	804	PBC	67	-
ROCK2	800	PBC	42	-
MAPK9	794	PBC	70	-
STK3	785	PBC	19	-
MAPK11	779	PBC	62	-
MAP2K4	774	PBC	33	-
NEK1	773	PBC	21	-
RPS6KA2	754	PBC	77	-
MARK4	750	PBC	64	-
MAP3K9	747	PBC	11	-
CAMK2G	731	PBC	63	-
PDK1	724	PBC	26	-
PRKCZ	717	PBC	15	-
AKT2	712	PBC	54	-
NEK6	707	PBC	9	-
DYRK2	701	PBC	61	-
TTBK1	701	PBC	24	-
IKBKE	699	PBC	19	-
PRKG2	696	PBC	42	-
CLK1	693	PBC	65	-
TAOK3	692	PBC	86	-
SRPK1	685	PBC	99	-
PRKG1	681	PBC	51	-
CAMK2B	676	PBC	55	-
PIM1	676	PBC	25	-
STK26	674	PBC	16	-
CDK4	670	PBC	23	-
PRKD1	658	PBC	25	-
RPS6KB1	656	PBC	34	-
PRKACB	653	PBC	47	-
NEK7	636	PBC	13	-
NEK4	618	PBC	9	-
MAPK10	609	PBC	47	-
STK25	604	PBC	5	-
TNIK	604	PBC	9	-
SIK2	595	PBC	32	-
PRKAA2	571	PBC	23	-
AURKC	570	PBC	23	-
PLK3	555	PBC	37	-
MAPKAPK3	552	PBC	39	-
PRKAA1	530	PBC	17	-
NLK	527	PBC	30	-
TAOK2	521	PBC	12	-
MAP2K2	516	PBC	38	-
RPS6KA3	516	PBC	40	-
CDK9	507	PBC	51	-
PHKG2	506	PBC	25	-
MAP3K11	505	PBC	15	-
NIM1K	503	PBC	22	-
PRKCH	502	PBC	18	-
MARK1	498	PBC	47	-
SGK1	496	PBC	30	-
TBK1	495	PBC	16	-
NEK9	494	PBC	6	-
MAPKAPK2	492	PBC	53	-
RPS6KA5	480	PBC	44	-
MAP3K10	479	PBC	8	-
TGFBR2	465	PBC	27	-
PLK4	462	PBC	5	-
DAPK1	458	PBC	25	-
ATR	456	PBC	4	-
MAP4K2	455	PBC	3	-
MAP3K20	450	PBC	9	-
PIM3	445	PBC	18	-
CDK6	444	PBC	30	-
MARK2	442	PBC	31	-
MAPKAPK5	441	PBC	40	-
MAP3K7	439	PBC	10	-
STK11	430	PBC	7	-
MARK3	427	PBC	38	-
TLK1	418	PBC	12	-
CAMK4	417	PBC	28	-
SGK3	417	PBC	25	-
GRK5	413	PBC	29	-
EIF2AK2	399	PBC	15	-
MATK	396	PBC	34	-
DYRK3	392	PBC	37	-
IRAK4	391	PBC	5	-
TSSK1B	381	PBC	20	-
MTOR	374	PBC	15	-
DCLK2	373	PBC	23	-
ACVR1B	366	PBC	23	-
SIK1	364	PBC	42	-
CSNK1G2	363	PBC	15	-
PRKACG	360	PBC	22	-
AKT3	347	PBC	32	-
TLK2	343	PBC	11	-
MKNK2	341	PBC	18	-
CSNK1G1	327	PBC	16	-
PRKD3	319	PBC	15	-
PAK4	314	PBC	30	-
RPS6KA6	312	PBC	28	-
TAOK1	309	PBC	6	-
MAP2K5	304	PBC	7	-
SRPK3	295	PBC	61	-
TSSK2	294	PBC	19	-
BMPR1B	289	PBC	13	-
LATS1	288	PBC	38	-
DYRK4	279	PBC	44	-
DSTYK	277	PBC	11	-
LATS2	277	PBC	23	-
NEK11	269	PBC	7	-
GRK7	267	PBC	16	-
DYRK1A	256	PBC	36	-
TGFBR1	253	PBC	17	-
WNK3	244	PBC	6	-
CHEK2	243	PBC	12	-
PKN1	243	PBC	12	-
CAMKK1	239	PBC	4	-
CAMK1	228	PBC	19	-
ACVR1	225	PBC	17	-
RPS6KA4	221	PBC	34	-
PBK	214	PBC	7	-
CILK1	210	PBC	16	-
PAK6	209	PBC	12	-
WNK1	209	PBC	3	-
CSNK1G3	206	PBC	8	-
PRKD2	206	PBC	17	-
NUAK2	205	PBC	13	-
FAM20C	204	PBC	41	-
DMPK	201	PBC	18	-
ACVR2A	200	PBC	22	-
MYLK2	191	PBC	10	-
GRK1	189	PBC	11	-
GRK3	187	PBC	6	-
MOK	187	PBC	8	-
ULK1	187	PBC	3	-
CAMK1D	174	PBC	17	-
PAK5	173	PBC	15	-
SLK	171	PBC	4	-
PRKX	169	PBC	16	-
DCLK1	163	PBC	8	-
RPS6KB2	161	PBC	9	-
PLK2	157	PBC	6	-
CLK2	155	PBC	13	-
MAP3K8	153	PBC	3	-
HIPK1	150	PBC	17	-
OXSR1	149	PBC	4	-
PIM2	147	PBC	9	-
GRK4	142	PBC	2	-
NUAK1	141	PBC	6	-
CDC42BPB	138	PBC	15	-
EEF2K	136	PBC	3	-
MAP3K2	132	PBC	15	-
CDC42BPA	130	PBC	13	-
HASPIN	130	PBC	1	-
STK38L	128	PBC	13	-
GRK6	121	PBC	5	-
PDK4	121	PBC	6	-
EIF2AK3	117	PBC	4	-
MOS	117	PBC	8	-
PDPK1	109	PBC	2	-
DAPK3	107	PBC	4	-
LRRK2	107	PBC	5	-
MAP3K3	106	PBC	8	-
PHKG1	104	PBC	6	-
STK39	104	PBC	6	-
CLK3	103	PBC	21	-
EIF2AK1	102	PBC	19	-
HIPK4	101	PBC	13	-
MAPK15	101	PBC	13	-
ACVR2B	97	PBC	13	-
MAP3K5	97	PBC	2	-
CDK3	96	PBC	2	-
BRSK2	95	PBC	12	-
CDC7	93	PBC	7	-
HIPK3	91	PBC	15	-
STK16	89	PBC	7	-
BUB1	70	PBC	3	-
CLK4	70	PBC	2	-
VRK1	68	PBC	1	-
STK10	60	PBC	1	-
BRSK1	59	PBC	4	-
DYRK1B	58	PBC	4	-
PASK	58	PBC	5	-
NEK3	57	PBC	2	-
BMPR2	55	PBC	3	-
STK33	54	PBC	7	-
BMPR1A	53	PBC	7	-
CDKL5	52	PBC	6	-
MAK	50	PBC	7	-
RIPK2	47	PBC	2	-
BRAF	46	PBC	5	-
MAP3K14	45	PBC	3	-
SRPK2	42	PBC	5	-
MYLK	38	PBC	2	-
CSNK1A1L	37	PBC	4	-
MAP3K15	37	PBC	7	-
PNCK	37	PBC	3	-
BCKDK	36	PBC	2	-
DAPK2	36	PBC	4	-
EIF2AK4	35	PBC	2	-
WNK4	34	PBC	3	-
UHMK1	25	PBC	2	-
MAP3K12	22	PBC	3	-
CDK14	21	PBC	2	-
CDK17	20	PBC	3	-
CDK16	19	PBC	2	-
RIPK3	15	PBC	1	-
TTBK2	15	PBC	2	-
CDK19	13	PBC	1	-
MAP3K6	10	PBC	1	-
PKN3	10	PBC	2	-
BMP2K	9	PBC	1	-

Statistics for Different Organisms

Organism	Frequency
Homo sapiens (Human)	1,075,990
Mus musculus (Mouse)	391,600
Rattus norvegicus (Rat)	183,916
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	122,967
Arabidopsis thaliana (Mouse-ear cress)	90,063
Zea mays (Maize)	48,599
Drosophila melanogaster (Fruit fly)	46,991
Oryza sativa subsp. japonica (Rice)	30,517
Dictyostelium discoideum (Social amoeba)	28,736
Caenorhabditis elegans	28,700
Bos taurus (Bovine)	25,766
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	24,828
Sus scrofa (Pig)	22,220
Medicago truncatula (Barrel medic) (Medicago tribuloides)	20,303
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)	18,650
Escherichia coli (strain K12)	17,541
Plasmodium falciparum (isolate 3D7)	15,731
Brachypodium distachyon (Purple false brome) (Trachynia distachya)	11,886
Trypanosoma cruzi Dm28c	11,558
Glycine max (Soybean) (Glycine hispida)	10,531
Toxoplasma gondii (strain ATCC 50611 / Me49)	9,661
Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	9,563
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	9,150
Danio rerio (Zebrafish) (Brachydanio rerio)	7,931
Gossypium hirsutum (Upland cotton) (Gossypium mexicanum)	7,748
Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)	7,331
Oryza sativa subsp. indica (Rice)	7,188
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica)	6,963
Toxoplasma gondii (strain ATCC 50861 / VEG)	6,173
Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	5,920
Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284) (Yeast) (Kluyveromyces thermotolerans)	5,634
Jatropha curcas (Barbados nut)	5,186
Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus)	5,184
Zygosaccharomyces rouxii (strain ATCC 2623 / CBS 732 / NBRC 1130 / NCYC 568 / NRRL Y-229) (Candida mogii)	5,149
Homo sapiens Human.	5,114
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	5,074
Xenopus laevis (African clawed frog)	5,072
Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17) (Kluyveromyces polysporus)	5,020
Naumovozyma castellii (strain ATCC 76901 / BCRC 22586 / CBS 4309 / NBRC 1992 / NRRL Y-12630) (Yeast) (Saccharomyces castellii)	4,959
Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324) (Yeast) (Candida guilliermondii)	4,805
Gallus gallus (Chicken)	4,745
Oryctolagus cuniculus (Rabbit)	4,493
Physcomitrium patens (Spreading-leaved earth moss) (Physcomitrella patens)	4,324
Triticum aestivum (Wheat)	4,171
Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545) (Yeast) (Pichia stipitis)	4,118
Stichopus japonicus (Sea cucumber)	4,102
Bacillus subtilis (strain 168)	4,092
Canis lupus familiaris (Dog) (Canis familiaris)	3,967
Sulfolobus islandicus (strain REY15A)	3,707
Chlamydomonas reinhardtii (Chlamydomonas smithii)	3,312

Data statistics of benchmark dataset for nine PTM types with sufficient data - [Go to the Download page]

PTM Type	Number of Proteins	Number of Positive sites	Number of Negative sites
Phosphorylation by CDK	1,020	1,503	29,823
Phosphorylation by MAPK	857	1,270	22,436
Phosphorylation by PKA	905	1,209	29,813
Phosphorylation by PKC	691	943	24,207
Phosphorylation by CK2	511	819	15,387
Phosphorylation by CAMKL	454	556	20,129
Phosphorylation by GSK	291	397	10,328
Phosphorylation by AKT	351	380	14,617
Phosphorylation by CAMK2	254	366	12,575
Phosphorylation by CK1	174	339	5,808
Phosphorylation by RSK	221	215	6,985
Phosphorylation by GRK	77	147	2,310
Phosphorylation by PKG	126	145	7,311
Phosphorylation by DYRK	109	142	3,470
Phosphorylation by MAPKAPK	100	125	3,096
Phosphorylation by DMPK	99	109	3,533
Phosphorylation by PKD	88	97	3,401
Phosphorylation by PDK1	77	93	2,274
Phosphorylation by SGK	63	77	3,057
Phosphorylation by RAD53	29	75	1,560
Phosphorylation by DAPK	51	53	1,284
Phosphorylation by PKN	26	50	866
Phosphorylation by CAMK1	34	44	2,342
Phosphorylation by MLCK	20	34	484
Phosphorylation by NDR	28	32	1,096
Acetylation	5,646	14,407	8,704
Citrullination	66	76	1,501
C-linked Glycosylation	39	113	159
Crotonylation	20	117	36
Formylation	130	172	1,452
Gamma-carboxyglutamic acid	54	319	553
Glutarylation	217	725	2,543
Glutathionylation	1,493	3,555	6,617
Hydroxylation	201	1,270	2,900
Lipoylation	28	29	779
Malonylation	2,768	7,635	17,371
Methylation	5,438	14,686	36,501
Nitration	61	64	983
N-linked Glycosylation	1,969	2,517	8,330
O-linked Glycosylation	1,298	4,470	37,969
S-diacylglycerol	23	57	59
S-nitrosylation	1,434	3,592	5,803
Succinylation	2,599	5,049	5,526
Sumoylation	1,432	5,191	16,066
Ubiquitination	4,453	9,767	8,579

Statistics of Currently Available External PTM Resources in dbPTM

Resource	Version	Number of PTM sites	Number of experimental PTM Sites	Number of putative sites	Number of Literatures
EPSD	Release 2024_04	2,118,477	2118477	0	59,444
BioGRID	4.4.237	621,153	563,757	57,396	85,467
dbPAF	1	483,001	483,001	0	15,139
CPLM	4	463,156	463,156	0	110,636
PhosphoSitePlus	V6.7.4	564,133	139,954	430,179	30,993
mUbiSiDa	Release 2013_10	111,208	111,208	0	102
The O-GlcNAc Database	v2.0	74,186	74,186	0	2,177
ActiveDriverDB	Release 2021_03	261,348	60,897	254,451	6,263
Phospho.ELM	Release 9.0	50,660	50,622	38	3,589
UbiNet	2	44,175	44,175	0	233
UniProtKB	Release 2021_03	396,480	106,129	290,351	10,727
dbPSP	2	19,296	19,296	0	471
ESBL	Release 2018_05	20,001	9,970	10,031	5
OGP	Release 2021	9,354	9,354	0	1
MetOSite	Release 2024_07	8,197	8,197	0	129
SwissPalm	Release 4.0	6,398	6,398	0	1,391
CarbonylDB	Release 2018_02	3,781	3,781	0	115
PredNTS	Release 2021	1,386	1,386	0	1
ProteomeXchange	Release 2021_04	539	464	75	243
PupDB	Release 1.3	311	195	116	4
PredGPI	Release 1.0	26	0	26	0
dbPTM	Release 2019	1,256,901	908,917	347,984	92,648
dbPTM	Release 2022	2,777,771	2,235,664	542,107	82,444
dbPTM	Release 2024	2,790,441	2,243,890	546,551	80,216

The statistics of non-synonymous SNPs (nsSNPs) altering PTM sites in Human

Data Category	Description	Resource	Number of Data
Experimental PTM Sites	The experimental PTM sites in human are integrated by dbPTM.	dbPTM 2022	878,258
Disease-associated SNPs	All published GWA studies are identified by literature search. Then the reported SNP-trait associations are extracted.	GWAS Catalog (2019)	275,247
Disease-associated PTM Sites	Merging the PTM sites and disease-associated SNPs for discovery of disease-associated single nucleotide polymorphism influencing PTM sites.		2,846

Citing dbPTM:
Chia-Ru Chung, Yun Tang, Yen-Peng Chiu, Shangfu Li, Wen-Kai Hsieh, Lantian Yao, Ying-Chih Chiang, Yuxuan Pang, Guan-Ting Chen, Kai-Chen Chou, You Sheng Paik, Phuong Lam Tran, Cheng-Pei Lin, Yu-Min Kao, Yi-Jie Chen, Wen-Chi Chang, Justin Bo-Kai Hsu, Jorng-Tzong Horng, Tzong-Yi Lee. "dbPTM 2025 update: comprehensive integration of PTMs and proteomic data for advanced insights into cancer research" Nucleic Acids Research, gkae1005 - [PubMed]
Zhongyan Li, Shangfu Li, Mengqi Luo, Jhih-Hua Jhong, Wenshuo Li, Lantian Yao, Yuxuan Pang, Zhuo Wang, Rulan Wang, Renfei Ma, Jinhan Yu, Hsien-Da Huang and Tzong-Yi Lee. "dbPTM in 2022: an updated database for exploring regulatory networks and functional associations of protein post-translational modifications" Nucleic Acids Research, Volume 50, Issue D1, 7 January 2022, Pages D471-D479 - [PubMed]
Kai-Yao Huang, Tzong-Yi Lee, Hui-Ju Kao, Chen-Tse Ma, Chao-Chun Lee, Tsai-Hsuan Lin, Wen-Chi Chang and Hsien-Da Huang. "dbPTM in 2019: exploring disease association and cross-talk of post-translational modifications" Nucleic Acids Research, Volume 47, Issue D1, 08 January 2019, Pages D298-308 - [PubMed]