Investigation of PTM crosstalk between two different types


In recent years, an increasing evidence for crosstalk between PTMs has been reported. Although mass spectrometry (MS)-based proteomics has substantially improved our knowledge about substrate site specificity of single PTM, this neglects the fact that the crosstalk of combinatorial PTMs may act in concert in the regulation of protein function. Due to the relatively limited information about the frequency and functional relevance of PTM crosstalk, in this update, the human PTM sites neighbouring with other PTM sites in a specified window length were subjected to functional enrichment analysis. This update confronts the current state of PTM crosstalk research and breaks the bottleneck of how proteomics may contribute to understanding PTM codes, revealing the next level of data complexity and proteomic limitation in prospective PTM research.

Investigation of PTM crosstalk.

#, Number of PTM crosstalk proteins

PTM Type#-10-9-8-7-6-5-4-3-2-1012345678910
O-linked Glycosylation---------------
Ubiquitination--
Glutarylation---------------
Phosphorylation
Succinylation-----------------
N-linked Glycosylation----------------------
Acetylation-
Sumoylation----------
Sulfoxidation--------------------
Malonylation-------------------
Neddylation--------------------
Gamma-carboxyglutamic acid----------------------
Methylation----------
S-palmitoylation----------------------
Myristoylation----------------------
Glutathionylation----------------------
S-nitrosylation-------------------
Crotonylation------------
Hydroxylation----------------------
Sulfation----------------------
Butyrylation-----------------
C-linked Glycosylation----------------------
Citrullination------------------
Deamidation----------------------
Geranylgeranylation----------------------
Lipoylation----------------------
Pyrrolidone carboxylic acid----------------------
Formation of an isopeptide bond--------------------
Farnesylation----------------------
Oxidation----------------------
GPI-anchor----------------------
Lactylation------------
AMPylation-------------------
Lactoylation--------------
Iodination----------------------
Amidation--------------------
Deamination--------------------
Nitration----------------------
Carboxylation----------------------
Hydroxyceramide ester----------------------
Carbamidation----------------------
Sulfhydration ----------------------
N-palmitoylation----------------------
Propionylation----------------------
Biotinylation----------------------
Carboxyethylation----------------------
Phosphatidylethanolamine amidation----------------------
Serotonylation--------------------
Decanoylation----------------------
Blocked amino end----------------------
O-palmitoleoylation----------------------
S-linked Glycosylation----------------------
S-cysteinylation----------------------
Octanoylation----------------------
Thiocarboxylation----------------------
Decarboxylation----------------------
Stearoylation----------------------
Pyruvate----------------------

#, Number of PTM crosstalk proteins

PTM Type#-10-9-8-7-6-5-4-3-2-1012345678910
O-linked Glycosylation
Ubiquitination
Glutarylation
Phosphorylation
Succinylation
N-linked Glycosylation
Sumoylation
Sulfoxidation
Malonylation
Neddylation
Gamma-carboxyglutamic acid----------------------
Methylation
S-palmitoylation
Myristoylation-----------------
Glutathionylation
S-nitrosylation
Crotonylation
Hydroxylation---
Sulfation-------------------
Butyrylation--
C-linked Glycosylation----------------------
Citrullination----
Deamidation-----
Geranylgeranylation----------------------
Lipoylation----------------------
Pyrrolidone carboxylic acid----------------------
Formation of an isopeptide bond----------------
Farnesylation-------------------
Oxidation---------------
GPI-anchor----------------------
Lactylation
AMPylation----------------------
Lactoylation
ADP-ribosylation-
Iodination----------------------
Amidation-------------------
Deamination---------------
Nitration-------------
Carboxylation----------------------
Hydroxyceramide ester----------------------
Carbamidation-------------------
Sulfhydration ----------------------
N-palmitoylation--------------------
Propionylation------------
Biotinylation----------------------
Carboxyethylation----------------------
Phosphatidylethanolamine amidation----------------------
Serotonylation-----------------
Decanoylation--------------------
Blocked amino end----------------------
O-palmitoleoylation----------------------
S-linked Glycosylation----------------------
S-cysteinylation----------------------
Octanoylation--------------------
Thiocarboxylation----------------------
Decarboxylation----------------------
Stearoylation----------------------
Pyruvate----------------------

#, Number of PTM crosstalk proteins

PTM Type#-10-9-8-7-6-5-4-3-2-1012345678910
O-linked Glycosylation--------------
Ubiquitination----------------------
Glutarylation----------------------
Phosphorylation-------
Succinylation----------------------
N-linked Glycosylation----------------------
Acetylation-------------------
Sumoylation----------------------
Sulfoxidation----------------------
Malonylation----------------------
Neddylation----------------------
Gamma-carboxyglutamic acid----------------------
Methylation--------------------
S-palmitoylation----------------------
Myristoylation----------------------
Glutathionylation----------------------
S-nitrosylation----------------------
Crotonylation----------------------
Hydroxylation----------------------
Sulfation-------------------
Butyrylation----------------------
C-linked Glycosylation----------------------
Citrullination----------------------
Deamidation----------------------
Geranylgeranylation----------------------
Lipoylation----------------------
Pyrrolidone carboxylic acid--------------------
Formation of an isopeptide bond----------------------
Farnesylation----------------------
Oxidation----------------------
GPI-anchor----------------------
Lactylation----------------------
AMPylation----------------------
Lactoylation----------------------
ADP-ribosylation--------------------
Iodination----------------------
Deamination----------------------
Nitration----------------------
Carboxylation----------------------
Hydroxyceramide ester----------------------
Carbamidation----------------------
Sulfhydration ----------------------
N-palmitoylation----------------------
Propionylation----------------------
Biotinylation----------------------
Carboxyethylation----------------------
Phosphatidylethanolamine amidation----------------------
Serotonylation----------------------
Decanoylation----------------------
Blocked amino end----------------------
O-palmitoleoylation----------------------
S-linked Glycosylation----------------------
S-cysteinylation----------------------
Octanoylation----------------------
Thiocarboxylation----------------------
Decarboxylation----------------------
Stearoylation----------------------
Pyruvate----------------------

#, Number of PTM crosstalk proteins

PTM Type#-10-9-8-7-6-5-4-3-2-1012345678910
O-linked Glycosylation---------------
Ubiquitination-------
Glutarylation---------
Phosphorylation-----
Succinylation--------------
N-linked Glycosylation----------------------
Acetylation--
Sumoylation---------
Sulfoxidation------------------
Malonylation-------------------
Neddylation----------------------
Gamma-carboxyglutamic acid----------------------
Methylation----
S-palmitoylation----------------------
Myristoylation----------------------
Glutathionylation----------------------
S-nitrosylation----------------------
Crotonylation-------
Hydroxylation-------------------
Sulfation----------------------
C-linked Glycosylation----------------------
Citrullination------------
Deamidation----------------------
Geranylgeranylation----------------------
Lipoylation----------------------
Pyrrolidone carboxylic acid----------------------
Formation of an isopeptide bond--------------------
Farnesylation----------------------
Oxidation----------------------
GPI-anchor----------------------
Lactylation------
AMPylation----------------------
Lactoylation-----
ADP-ribosylation-----------------
Iodination----------------------
Amidation----------------------
Deamination--------------------
Nitration----------------------
Carboxylation----------------------
Hydroxyceramide ester----------------------
Carbamidation----------------------
Sulfhydration ----------------------
N-palmitoylation----------------------
Propionylation-------------
Biotinylation----------------------
Carboxyethylation----------------------
Phosphatidylethanolamine amidation----------------------
Serotonylation--------------------
Decanoylation----------------------
Blocked amino end----------------------
O-palmitoleoylation----------------------
S-linked Glycosylation----------------------
S-cysteinylation----------------------
Octanoylation----------------------
Thiocarboxylation----------------------
Decarboxylation----------------------
Stearoylation----------------------
Pyruvate----------------------

#, Number of PTM crosstalk proteins

PTM Type#-10-9-8-7-6-5-4-3-2-1012345678910
O-linked Glycosylation-------------------
Ubiquitination----------------------
Glutarylation----------------------
Phosphorylation--------------
Succinylation----------------------
N-linked Glycosylation-------------------
Acetylation----------------------
Sumoylation----------------------
Sulfoxidation----------------------
Malonylation----------------------
Neddylation----------------------
Gamma-carboxyglutamic acid----------------------
Methylation----------------------
S-palmitoylation----------------------
Myristoylation----------------------
Glutathionylation----------------------
S-nitrosylation----------------------
Crotonylation----------------------
Hydroxylation----------------------
Sulfation----------------------
Butyrylation----------------------
Citrullination----------------------
Deamidation----------------------
Geranylgeranylation----------------------
Lipoylation----------------------
Pyrrolidone carboxylic acid----------------------
Formation of an isopeptide bond----------------------
Farnesylation----------------------
Oxidation----------------------
GPI-anchor----------------------
Lactylation----------------------
AMPylation----------------------
Lactoylation----------------------
ADP-ribosylation----------------------
Iodination----------------------
Amidation----------------------
Deamination----------------------
Nitration----------------------
Carboxylation----------------------
Hydroxyceramide ester----------------------
Carbamidation----------------------
Sulfhydration ----------------------
N-palmitoylation----------------------
Propionylation----------------------
Biotinylation----------------------
Carboxyethylation----------------------
Phosphatidylethanolamine amidation----------------------
Serotonylation----------------------
Decanoylation----------------------
Blocked amino end----------------------
O-palmitoleoylation----------------------
S-linked Glycosylation----------------------
S-cysteinylation----------------------
Octanoylation----------------------
Thiocarboxylation----------------------
Decarboxylation----------------------
Stearoylation----------------------
Pyruvate----------------------

#, Number of PTM crosstalk proteins

PTM Type#-10-9-8-7-6-5-4-3-2-1012345678910
O-linked Glycosylation----------------------
Ubiquitination----------------------
Glutarylation----------------------
Phosphorylation--------------------
Succinylation----------------------
N-linked Glycosylation----------------------
Acetylation----------------------
Sumoylation----------------------
Sulfoxidation----------------------
Malonylation----------------------
Neddylation----------------------
Gamma-carboxyglutamic acid----------------------
Methylation----------------------
S-palmitoylation----------------------
Myristoylation----------------------
Glutathionylation----------------------
S-nitrosylation----------------------
Crotonylation----------------------
Hydroxylation----------------------
Sulfation----------------------
Butyrylation----------------------
C-linked Glycosylation----------------------
Citrullination----------------------
Deamidation----------------------
Geranylgeranylation----------------------
Lipoylation----------------------
Pyrrolidone carboxylic acid----------------------
Formation of an isopeptide bond----------------------
Farnesylation----------------------
Oxidation----------------------
GPI-anchor----------------------
Lactylation----------------------
AMPylation----------------------
Lactoylation----------------------
ADP-ribosylation----------------------
Iodination----------------------
Amidation----------------------
Deamination----------------------
Nitration----------------------
Hydroxyceramide ester----------------------
Carbamidation----------------------
Sulfhydration ----------------------
N-palmitoylation----------------------
Propionylation----------------------
Biotinylation----------------------
Carboxyethylation----------------------
Phosphatidylethanolamine amidation----------------------
Serotonylation----------------------
Decanoylation----------------------
Blocked amino end----------------------
O-palmitoleoylation----------------------
S-linked Glycosylation----------------------
S-cysteinylation----------------------
Octanoylation----------------------
Thiocarboxylation----------------------
Decarboxylation----------------------
Stearoylation----------------------
Pyruvate----------------------

#, Number of PTM crosstalk proteins

PTM Type#-10-9-8-7-6-5-4-3-2-1012345678910
O-linked Glycosylation---------------
Ubiquitination--------------
Glutarylation--------------
Phosphorylation--
Succinylation------------------
N-linked Glycosylation----------------------
Acetylation----
Sumoylation--------------
Sulfoxidation----------------------
Malonylation----------------------
Neddylation----------------------
Gamma-carboxyglutamic acid----------------------
Methylation--------
S-palmitoylation----------------------
Myristoylation----------------------
Glutathionylation----------------------
S-nitrosylation----------------------
Crotonylation-----------
Hydroxylation----------------------
Sulfation----------------------
Butyrylation------------
C-linked Glycosylation----------------------
Deamidation----------------------
Geranylgeranylation----------------------
Lipoylation----------------------
Pyrrolidone carboxylic acid----------------------
Formation of an isopeptide bond-------------------
Farnesylation----------------------
Oxidation----------------------
GPI-anchor----------------------
Lactylation------------
AMPylation----------------------
Lactoylation------------
ADP-ribosylation------------------
Iodination----------------------
Amidation----------------------
Deamination-------------------
Nitration----------------------
Carboxylation----------------------
Hydroxyceramide ester----------------------
Carbamidation----------------------
Sulfhydration ----------------------
N-palmitoylation----------------------
Propionylation--------------------
Biotinylation----------------------
Carboxyethylation----------------------
Phosphatidylethanolamine amidation----------------------
Serotonylation-------------------
Decanoylation----------------------
Blocked amino end----------------------
O-palmitoleoylation----------------------
S-linked Glycosylation----------------------
S-cysteinylation----------------------
Octanoylation----------------------
Thiocarboxylation----------------------
Decarboxylation----------------------
Stearoylation----------------------
Pyruvate----------------------

#, Number of PTM crosstalk proteins

PTM Type#-10-9-8-7-6-5-4-3-2-1012345678910
O-linked Glycosylation-------------
Ubiquitination
Glutarylation-----
Phosphorylation-
Succinylation----------
N-linked Glycosylation----------------------
Acetylation
Sumoylation-----
Sulfoxidation----------------------
Malonylation------------
Neddylation----------------
Gamma-carboxyglutamic acid----------------------
Methylation----
S-palmitoylation----------------------
Myristoylation----------------------
Glutathionylation----------------------
S-nitrosylation----------------------
Hydroxylation-----------------
Sulfation----------------------
Butyrylation-------
C-linked Glycosylation----------------------
Citrullination-----------
Deamidation----------------------
Geranylgeranylation----------------------
Lipoylation----------------------
Pyrrolidone carboxylic acid----------------------
Formation of an isopeptide bond-------------------
Farnesylation----------------------
Oxidation----------------------
GPI-anchor----------------------
Lactylation--
AMPylation----------------------
Lactoylation--
ADP-ribosylation------------
Iodination----------------------
Amidation----------------------
Deamination-------------------
Nitration----------------------
Carboxylation----------------------
Hydroxyceramide ester----------------------
Carbamidation----------------------
Sulfhydration ----------------------
N-palmitoylation----------------------
Propionylation----------------
Biotinylation----------------------
Carboxyethylation----------------------
Phosphatidylethanolamine amidation----------------------
Serotonylation-------------------
Decanoylation----------------------
Blocked amino end----------------------
O-palmitoleoylation----------------------
S-linked Glycosylation----------------------
S-cysteinylation----------------------
Octanoylation----------------------
Thiocarboxylation----------------------
Decarboxylation----------------------
Stearoylation----------------------
Pyruvate----------------------

#, Number of PTM crosstalk proteins

PTM Type#-10-9-8-7-6-5-4-3-2-1012345678910
O-linked Glycosylation----------------------
Ubiquitination---------
Glutarylation----------------------
Phosphorylation-----
Succinylation--------------------
N-linked Glycosylation----------------
Acetylation-----
Sumoylation-----------------
Sulfoxidation--------------------
Malonylation----------------
Neddylation----------------------
Gamma-carboxyglutamic acid----------------------
Methylation---------------
S-palmitoylation-----------------
Myristoylation----------------------
Glutathionylation-----------------
S-nitrosylation-----------------
Crotonylation----------------------
Hydroxylation----------------------
Sulfation----------------------
Butyrylation----------------------
C-linked Glycosylation----------------------
Citrullination----------------------
Geranylgeranylation----------------------
Lipoylation----------------------
Pyrrolidone carboxylic acid----------------------
Formation of an isopeptide bond----------------------
Farnesylation----------------------
Oxidation----------------------
GPI-anchor----------------------
Lactylation----------------------
AMPylation----------------------
Lactoylation----------------------
ADP-ribosylation----------------------
Iodination----------------------
Amidation----------------------
Deamination----------------------
Nitration----------------------
Carboxylation----------------------
Hydroxyceramide ester----------------------
Carbamidation----------------------
Sulfhydration ----------------------
N-palmitoylation----------------------
Propionylation----------------------
Biotinylation----------------------
Carboxyethylation----------------------
Phosphatidylethanolamine amidation----------------------
Serotonylation----------------------
Decanoylation----------------------
Blocked amino end----------------------
O-palmitoleoylation----------------------
S-linked Glycosylation----------------------
S-cysteinylation----------------------
Octanoylation----------------------
Thiocarboxylation----------------------
Decarboxylation----------------------
Stearoylation----------------------
Pyruvate----------------------

#, Number of PTM crosstalk proteins

PTM Type#-10-9-8-7-6-5-4-3-2-1012345678910
O-linked Glycosylation--------------------
Ubiquitination---------
Glutarylation--------------------
Phosphorylation--------------
Succinylation--------------------
N-linked Glycosylation----------------------
Acetylation---------------
Sumoylation--------------------
Sulfoxidation--------------------
Malonylation----------------------
Neddylation----------------------
Gamma-carboxyglutamic acid----------------------
Methylation----------------
S-palmitoylation----------------------
Myristoylation----------------------
Glutathionylation----------------------
S-nitrosylation----------------------
Crotonylation-------------------
Hydroxylation----------------------
Sulfation----------------------
Butyrylation--------------------
C-linked Glycosylation----------------------
Citrullination-------------------
Deamidation----------------------
Geranylgeranylation----------------------
Lipoylation----------------------
Pyrrolidone carboxylic acid-------------------
Formation of an isopeptide bond--------------------
Farnesylation----------------------
Oxidation----------------------
GPI-anchor----------------------
Lactylation-------------------
AMPylation----------------------
Lactoylation--------------------
ADP-ribosylation--------------------
Iodination----------------------
Amidation----------------------
Nitration----------------------
Carboxylation----------------------
Hydroxyceramide ester----------------------
Carbamidation----------------------
Sulfhydration ----------------------
N-palmitoylation----------------------
Propionylation----------------------
Biotinylation----------------------
Carboxyethylation----------------------
Phosphatidylethanolamine amidation----------------------
Serotonylation--------------------
Decanoylation----------------------
Blocked amino end----------------------
O-palmitoleoylation----------------------
S-linked Glycosylation----------------------
S-cysteinylation----------------------
Octanoylation----------------------
Thiocarboxylation----------------------
Decarboxylation----------------------
Stearoylation----------------------
Pyruvate----------------------

#, Number of PTM crosstalk proteins

PTM Type#-10-9-8-7-6-5-4-3-2-1012345678910
O-linked Glycosylation--------------------
Ubiquitination-------------------
Glutarylation--------------------
Phosphorylation--------------
Succinylation--------------------
N-linked Glycosylation----------------------
Acetylation----------------
Sumoylation--------------------
Sulfoxidation----------------------
Malonylation----------------------
Neddylation----------------------
Gamma-carboxyglutamic acid----------------------
Methylation----------------
S-palmitoylation----------------------
Myristoylation----------------------
Glutathionylation----------------------
S-nitrosylation----------------------
Crotonylation-------------------
Hydroxylation----------------------
Sulfation----------------------
Butyrylation--------------------
C-linked Glycosylation----------------------
Citrullination-------------------
Deamidation----------------------
Geranylgeranylation----------------------
Lipoylation----------------------
Pyrrolidone carboxylic acid----------------------
Farnesylation----------------------
Oxidation----------------------
GPI-anchor----------------------
Lactylation-------------------
AMPylation----------------------
Lactoylation--------------------
ADP-ribosylation--------------------
Iodination----------------------
Amidation----------------------
Deamination--------------------
Nitration----------------------
Carboxylation----------------------
Hydroxyceramide ester----------------------
Carbamidation----------------------
Sulfhydration ----------------------
N-palmitoylation----------------------
Propionylation----------------------
Biotinylation----------------------
Carboxyethylation----------------------
Phosphatidylethanolamine amidation----------------------
Serotonylation--------------------
Decanoylation----------------------
Blocked amino end----------------------
O-palmitoleoylation----------------------
S-linked Glycosylation----------------------
S-cysteinylation----------------------
Octanoylation----------------------
Thiocarboxylation----------------------
Decarboxylation----------------------
Stearoylation----------------------
Pyruvate----------------------

#, Number of PTM crosstalk proteins

PTM Type#-10-9-8-7-6-5-4-3-2-1012345678910
O-linked Glycosylation----------------------
Ubiquitination----------------
Glutarylation----------------------
Phosphorylation-------------
Succinylation----------------------
N-linked Glycosylation----------------------
Acetylation----------------------
Sumoylation----------------------
Sulfoxidation----------------------
Malonylation----------------------
Neddylation----------------------
Gamma-carboxyglutamic acid----------------------
Methylation-------------------
S-palmitoylation----------------
Myristoylation----------------------
Glutathionylation----------------------
S-nitrosylation--------------------
Crotonylation----------------------
Hydroxylation----------------------
Sulfation----------------------
Butyrylation----------------------
C-linked Glycosylation----------------------
Citrullination----------------------
Deamidation----------------------
Lipoylation----------------------
Pyrrolidone carboxylic acid----------------------
Formation of an isopeptide bond----------------------
Farnesylation--------------------
Oxidation----------------------
GPI-anchor----------------------
Lactylation----------------------
AMPylation----------------------
Lactoylation----------------------
ADP-ribosylation----------------------
Iodination----------------------
Amidation----------------------
Deamination----------------------
Nitration----------------------
Carboxylation----------------------
Hydroxyceramide ester----------------------
Carbamidation----------------------
Sulfhydration ----------------------
N-palmitoylation----------------------
Propionylation----------------------
Biotinylation----------------------
Carboxyethylation----------------------
Phosphatidylethanolamine amidation----------------------
Serotonylation----------------------
Decanoylation----------------------
Blocked amino end----------------------
O-palmitoleoylation----------------------
S-linked Glycosylation----------------------
S-cysteinylation----------------------
Octanoylation----------------------
Thiocarboxylation----------------------
Decarboxylation----------------------
Stearoylation----------------------
Pyruvate----------------------

#, Number of PTM crosstalk proteins

PTM Type#-10-9-8-7-6-5-4-3-2-1012345678910
O-linked Glycosylation--------
Ubiquitination-
Phosphorylation-
Succinylation-----
N-linked Glycosylation----------------------
Acetylation
Sumoylation-------
Sulfoxidation---------
Malonylation-------------
Neddylation------------
Gamma-carboxyglutamic acid----------------------
Methylation--
S-palmitoylation--------------------
Myristoylation----------------------
Glutathionylation----------------------
S-nitrosylation--------------------
Crotonylation-----
Hydroxylation---------------
Sulfation----------------------
Butyrylation---------
C-linked Glycosylation----------------------
Citrullination--------------
Deamidation----------------------
Geranylgeranylation----------------------
Lipoylation----------------------
Pyrrolidone carboxylic acid----------------------
Formation of an isopeptide bond--------------------
Farnesylation----------------------
Oxidation----------------------
GPI-anchor----------------------
Lactylation----------
AMPylation----------------------
Lactoylation------
ADP-ribosylation---------------
Iodination----------------------
Amidation----------------------
Deamination--------------------
Nitration----------------------
Carboxylation----------------------
Hydroxyceramide ester----------------------
Carbamidation----------------------
Sulfhydration ----------------------
N-palmitoylation----------------------
Propionylation---------------
Biotinylation----------------------
Carboxyethylation----------------------
Phosphatidylethanolamine amidation----------------------
Serotonylation--------------------
Decanoylation----------------------
Blocked amino end----------------------
O-palmitoleoylation----------------------
S-linked Glycosylation----------------------
S-cysteinylation----------------------
Octanoylation----------------------
Thiocarboxylation----------------------
Decarboxylation----------------------
Stearoylation----------------------
Pyruvate----------------------

#, Number of PTM crosstalk proteins

PTM Type#-10-9-8-7-6-5-4-3-2-1012345678910
O-linked Glycosylation---
Ubiquitination
Glutarylation----------------------
Phosphorylation
Succinylation--
N-linked Glycosylation-----------------
Acetylation
Sumoylation---
Sulfoxidation-
Malonylation-
Neddylation----
Gamma-carboxyglutamic acid----------------------
Methylation
S-palmitoylation-----
Myristoylation----------------------
S-nitrosylation--
Crotonylation----------------------
Hydroxylation----------------------
Sulfation--------------------
Butyrylation----------------------
C-linked Glycosylation----------------------
Citrullination----------------------
Deamidation-----------------
Geranylgeranylation----------------------
Lipoylation----------------------
Pyrrolidone carboxylic acid----------------------
Formation of an isopeptide bond----------------------
Farnesylation------------------
Oxidation--------------------
GPI-anchor----------------------
Lactylation----------------------
AMPylation----------------------
Lactoylation----------------------
ADP-ribosylation----------------------
Iodination----------------------
Amidation----------------------
Deamination----------------------
Nitration----------------------
Carboxylation----------------------
Hydroxyceramide ester----------------------
Carbamidation--------------------
Sulfhydration --------------------
N-palmitoylation----------------------
Propionylation----------------------
Biotinylation----------------------
Carboxyethylation----------------------
Phosphatidylethanolamine amidation----------------------
Serotonylation----------------------
Decanoylation----------------------
Blocked amino end----------------------
O-palmitoleoylation----------------------
S-linked Glycosylation----------------------
S-cysteinylation----------------------
Octanoylation----------------------
Thiocarboxylation----------------------
Decarboxylation----------------------
Stearoylation----------------------
Pyruvate----------------------

#, Number of PTM crosstalk proteins

PTM Type#-10-9-8-7-6-5-4-3-2-1012345678910
O-linked Glycosylation-------
Ubiquitination
Glutarylation---------------
Phosphorylation--
Succinylation---------------
N-linked Glycosylation-------------------
Acetylation---
Sumoylation--------------
Sulfoxidation-----------------
Malonylation----------
Neddylation------------------
Gamma-carboxyglutamic acid----------------------
Methylation-------------
S-palmitoylation----------------------
Myristoylation----------------------
Glutathionylation----------------------
S-nitrosylation--------------------
Crotonylation-----------------
Sulfation----------------------
Butyrylation-------------------
C-linked Glycosylation----------------------
Citrullination----------------------
Deamidation----------------------
Geranylgeranylation----------------------
Lipoylation----------------------
Pyrrolidone carboxylic acid------------------
Formation of an isopeptide bond----------------------
Farnesylation----------------------
Oxidation--------------------
GPI-anchor----------------------
Lactylation--------------------
AMPylation----------------------
Lactoylation--------------
ADP-ribosylation----------------------
Iodination----------------------
Amidation----------------------
Deamination----------------------
Nitration----------------------
Carboxylation----------------------
Hydroxyceramide ester----------------------
Carbamidation----------------------
Sulfhydration ----------------------
N-palmitoylation----------------------
Propionylation-------------------
Biotinylation----------------------
Carboxyethylation----------------------
Phosphatidylethanolamine amidation----------------------
Serotonylation----------------------
Decanoylation----------------------
Blocked amino end----------------------
O-palmitoleoylation----------------------
S-linked Glycosylation----------------------
S-cysteinylation----------------------
Octanoylation----------------------
Thiocarboxylation----------------------
Decarboxylation----------------------
Stearoylation----------------------
Pyruvate----------------------

#, Number of PTM crosstalk proteins

PTM Type#-10-9-8-7-6-5-4-3-2-1012345678910
O-linked Glycosylation-----------
Ubiquitination--
Glutarylation------
Phosphorylation-
Succinylation------------
N-linked Glycosylation----------------------
Acetylation
Sumoylation------
Sulfoxidation-------------------
Malonylation------------
Neddylation------------
Gamma-carboxyglutamic acid----------------------
Methylation--
S-palmitoylation----------------------
Myristoylation----------------------
Glutathionylation----------------------
S-nitrosylation----------------------
Crotonylation--
Hydroxylation--------------
Sulfation----------------------
Butyrylation-----
C-linked Glycosylation----------------------
Citrullination------------
Deamidation----------------------
Geranylgeranylation----------------------
Lipoylation----------------------
Pyrrolidone carboxylic acid----------------------
Formation of an isopeptide bond--------------------
Farnesylation----------------------
Oxidation----------------------
GPI-anchor----------------------
Lactylation-
AMPylation----------------------
ADP-ribosylation--------------
Iodination----------------------
Amidation----------------------
Deamination--------------------
Nitration----------------------
Carboxylation----------------------
Hydroxyceramide ester----------------------
Carbamidation----------------------
Sulfhydration ----------------------
N-palmitoylation----------------------
Propionylation--------------
Biotinylation----------------------
Carboxyethylation----------------------
Phosphatidylethanolamine amidation----------------------
Serotonylation--------------------
Decanoylation----------------------
Blocked amino end----------------------
O-palmitoleoylation----------------------
S-linked Glycosylation----------------------
S-cysteinylation----------------------
Octanoylation----------------------
Thiocarboxylation----------------------
Decarboxylation----------------------
Stearoylation----------------------
Pyruvate----------------------

#, Number of PTM crosstalk proteins

PTM Type#-10-9-8-7-6-5-4-3-2-1012345678910
O-linked Glycosylation---------------
Ubiquitination
Glutarylation----------
Phosphorylation-
Succinylation--------------
N-linked Glycosylation----------------------
Acetylation
Sumoylation------
Sulfoxidation----------------------
Malonylation-------------
Neddylation---------------
Gamma-carboxyglutamic acid----------------------
Methylation---
S-palmitoylation----------------------
Myristoylation----------------------
Glutathionylation----------------------
S-nitrosylation----------------------
Crotonylation--
Hydroxylation--------------------
Sulfation----------------------
Butyrylation------
C-linked Glycosylation----------------------
Citrullination------------
Deamidation----------------------
Geranylgeranylation----------------------
Lipoylation----------------------
Pyrrolidone carboxylic acid----------------------
Formation of an isopeptide bond-------------------
Farnesylation----------------------
Oxidation----------------------
GPI-anchor----------------------
AMPylation----------------------
Lactoylation-
ADP-ribosylation------------
Iodination----------------------
Amidation----------------------
Deamination-------------------
Nitration----------------------
Carboxylation----------------------
Hydroxyceramide ester----------------------
Carbamidation----------------------
Sulfhydration ----------------------
N-palmitoylation----------------------
Propionylation---------------
Biotinylation----------------------
Carboxyethylation----------------------
Phosphatidylethanolamine amidation----------------------
Serotonylation-------------------
Decanoylation----------------------
Blocked amino end----------------------
O-palmitoleoylation----------------------
S-linked Glycosylation----------------------
S-cysteinylation----------------------
Octanoylation----------------------
Thiocarboxylation----------------------
Decarboxylation----------------------
Stearoylation----------------------
Pyruvate----------------------

#, Number of PTM crosstalk proteins

PTM Type#-10-9-8-7-6-5-4-3-2-1012345678910
O-linked Glycosylation----------------------
Ubiquitination--------------------
Glutarylation----------------------
Phosphorylation---------------
Succinylation----------------------
N-linked Glycosylation----------------------
Acetylation----------------------
Sumoylation----------------------
Sulfoxidation----------------------
Malonylation----------------------
Neddylation----------------------
Gamma-carboxyglutamic acid----------------------
Methylation----------------------
S-palmitoylation----------------------
Myristoylation----------------------
Glutathionylation----------------------
S-nitrosylation----------------------
Crotonylation----------------------
Hydroxylation----------------------
Sulfation----------------------
Butyrylation----------------------
C-linked Glycosylation----------------------
Citrullination----------------------
Deamidation----------------------
Geranylgeranylation----------------------
Pyrrolidone carboxylic acid----------------------
Formation of an isopeptide bond----------------------
Farnesylation----------------------
Oxidation----------------------
GPI-anchor----------------------
Lactylation----------------------
AMPylation----------------------
Lactoylation----------------------
ADP-ribosylation----------------------
Iodination----------------------
Amidation----------------------
Deamination----------------------
Nitration----------------------
Carboxylation----------------------
Hydroxyceramide ester----------------------
Carbamidation----------------------
Sulfhydration ----------------------
N-palmitoylation----------------------
Propionylation----------------------
Biotinylation--------------------
Carboxyethylation----------------------
Phosphatidylethanolamine amidation----------------------
Serotonylation----------------------
Decanoylation----------------------
Blocked amino end----------------------
O-palmitoleoylation----------------------
S-linked Glycosylation----------------------
S-cysteinylation----------------------
Octanoylation----------------------
Thiocarboxylation----------------------
Decarboxylation----------------------
Stearoylation----------------------
Pyruvate----------------------

#, Number of PTM crosstalk proteins

PTM Type#-10-9-8-7-6-5-4-3-2-1012345678910
O-linked Glycosylation
Ubiquitination
Glutarylation-------------
Phosphorylation
Succinylation
N-linked Glycosylation-------------------
Acetylation
Sumoylation
Sulfoxidation-
Neddylation--
Gamma-carboxyglutamic acid----------------------
Methylation
S-palmitoylation--
Myristoylation----------------------
Glutathionylation-
S-nitrosylation-
Crotonylation------------
Hydroxylation----------
Sulfation----------------------
Butyrylation-------------------
C-linked Glycosylation----------------------
Citrullination----------------------
Deamidation----------------
Geranylgeranylation----------------------
Lipoylation----------------------
Pyrrolidone carboxylic acid----------------------
Formation of an isopeptide bond----------------------
Farnesylation----------------------
Oxidation----------------------
GPI-anchor----------------------
Lactylation-------------
AMPylation----------------------
Lactoylation------------
ADP-ribosylation-------------------
Iodination----------------------
Amidation----------------------
Deamination----------------------
Nitration------------------
Carboxylation----------------------
Hydroxyceramide ester----------------------
Carbamidation----------------------
Sulfhydration ----------------------
N-palmitoylation----------------------
Propionylation-------------------
Biotinylation----------------------
Carboxyethylation----------------------
Phosphatidylethanolamine amidation----------------------
Serotonylation----------------------
Decanoylation----------------------
Blocked amino end----------------------
O-palmitoleoylation----------------------
S-linked Glycosylation----------------------
S-cysteinylation----------------------
Octanoylation----------------------
Thiocarboxylation----------------------
Decarboxylation----------------------
Stearoylation----------------------
Pyruvate----------------------

#, Number of PTM crosstalk proteins

PTM Type#-10-9-8-7-6-5-4-3-2-1012345678910
O-linked Glycosylation
Ubiquitination
Glutarylation--
Phosphorylation
Succinylation-
N-linked Glycosylation---------
Acetylation
Sumoylation
Sulfoxidation-
Malonylation
Neddylation--
Gamma-carboxyglutamic acid----------------------
S-palmitoylation
Myristoylation--------------------
Glutathionylation
S-nitrosylation-
Crotonylation----
Hydroxylation-------------
Sulfation----------------------
Butyrylation----
C-linked Glycosylation----------------------
Citrullination--------
Deamidation---------------
Geranylgeranylation-------------------
Lipoylation----------------------
Pyrrolidone carboxylic acid----------------------
Formation of an isopeptide bond----------------
Farnesylation--------------------
Oxidation------------------
GPI-anchor----------------------
Lactylation---
AMPylation----------------------
Lactoylation--
ADP-ribosylation----------
Iodination----------------------
Amidation--------------------
Deamination----------------
Nitration----------------------
Carboxylation----------------------
Hydroxyceramide ester----------------------
Carbamidation--------------------
Sulfhydration ----------------------
N-palmitoylation----------------------
Propionylation---------------
Biotinylation----------------------
Carboxyethylation----------------------
Phosphatidylethanolamine amidation----------------------
Serotonylation----------------
Decanoylation----------------------
Blocked amino end----------------------
O-palmitoleoylation----------------------
S-linked Glycosylation----------------------
S-cysteinylation----------------------
Octanoylation----------------------
Thiocarboxylation----------------------
Decarboxylation----------------------
Stearoylation----------------------
Pyruvate----------------------

#, Number of PTM crosstalk proteins

PTM Type#-10-9-8-7-6-5-4-3-2-1012345678910
O-linked Glycosylation-
Ubiquitination
Glutarylation----------------------
Phosphorylation
Succinylation----------------
Acetylation
Sumoylation-----------------
Sulfoxidation-----------
Malonylation-------------------
Neddylation-------------------
Gamma-carboxyglutamic acid----------------------
Methylation---------
S-palmitoylation-------
Myristoylation----------------------
Glutathionylation-----------------
S-nitrosylation-------
Crotonylation----------------------
Hydroxylation-------------------
Sulfation------
Butyrylation----------------------
C-linked Glycosylation-------------------
Citrullination----------------------
Deamidation----------------
Geranylgeranylation----------------------
Lipoylation----------------------
Pyrrolidone carboxylic acid------------------
Formation of an isopeptide bond----------------------
Farnesylation----------------------
Oxidation-------------------
GPI-anchor-------------------
Lactylation----------------------
AMPylation----------------------
Lactoylation----------------------
ADP-ribosylation----------------------
Iodination------------------
Amidation----------------------
Deamination----------------------
Nitration----------------------
Carboxylation----------------------
Hydroxyceramide ester----------------------
Carbamidation----------------------
Sulfhydration ----------------------
N-palmitoylation----------------------
Propionylation----------------------
Biotinylation----------------------
Carboxyethylation----------------------
Phosphatidylethanolamine amidation----------------------
Serotonylation----------------------
Decanoylation----------------------
Blocked amino end----------------------
O-palmitoleoylation----------------------
S-linked Glycosylation----------------------
S-cysteinylation----------------------
Octanoylation----------------------
Thiocarboxylation----------------------
Decarboxylation----------------------
Stearoylation----------------------
Pyruvate----------------------

#, Number of PTM crosstalk proteins

PTM Type#-10-9-8-7-6-5-4-3-2-1012345678910
O-linked Glycosylation----------
Ubiquitination
Glutarylation------------
Phosphorylation
Succinylation--------
N-linked Glycosylation-------------------
Acetylation
Sumoylation-
Sulfoxidation
Malonylation--
Gamma-carboxyglutamic acid----------------------
Methylation--
S-palmitoylation---------
Myristoylation----------------------
Glutathionylation----
S-nitrosylation------
Crotonylation----------------
Hydroxylation------------------
Sulfation----------------------
Butyrylation----------------------
C-linked Glycosylation----------------------
Citrullination----------------------
Deamidation----------------------
Geranylgeranylation----------------------
Lipoylation----------------------
Pyrrolidone carboxylic acid----------------------
Formation of an isopeptide bond----------------------
Farnesylation----------------------
Oxidation----------------------
GPI-anchor----------------------
Lactylation---------------
AMPylation----------------------
Lactoylation------------
ADP-ribosylation--------------------
Iodination----------------------
Amidation----------------------
Deamination----------------------
Nitration----------------------
Carboxylation----------------------
Hydroxyceramide ester----------------------
Carbamidation----------------------
Sulfhydration ----------------------
N-palmitoylation----------------------
Propionylation----------------------
Biotinylation----------------------
Carboxyethylation----------------------
Phosphatidylethanolamine amidation----------------------
Serotonylation----------------------
Decanoylation----------------------
Blocked amino end----------------------
O-palmitoleoylation----------------------
S-linked Glycosylation----------------------
S-cysteinylation----------------------
Octanoylation----------------------
Thiocarboxylation----------------------
Decarboxylation----------------------
Stearoylation----------------------
Pyruvate----------------------

#, Number of PTM crosstalk proteins

PTM Type#-10-9-8-7-6-5-4-3-2-1012345678910
Ubiquitination
Glutarylation--------
Phosphorylation
Succinylation---
N-linked Glycosylation-
Acetylation
Sumoylation-
Sulfoxidation
Malonylation
Neddylation----------
Gamma-carboxyglutamic acid-----------------
Methylation
S-palmitoylation----
Myristoylation------------------
Glutathionylation---
S-nitrosylation-
Crotonylation-------------
Hydroxylation-------
Sulfation--------
Butyrylation---------------
C-linked Glycosylation-------------------
Citrullination---------------
Deamidation----------------------
Geranylgeranylation----------------------
Lipoylation----------------------
Pyrrolidone carboxylic acid-------------------
Formation of an isopeptide bond--------------------
Farnesylation----------------------
Oxidation-------------------
GPI-anchor-------------------
Lactylation---------------
AMPylation------------------
Lactoylation-----------
ADP-ribosylation---------------
Iodination----------------------
Amidation--------------
Deamination--------------------
Nitration----------------------
Carboxylation----------------------
Hydroxyceramide ester----------------------
Carbamidation----------------------
Sulfhydration ----------------------
N-palmitoylation----------------------
Propionylation--------------------
Biotinylation----------------------
Carboxyethylation----------------------
Phosphatidylethanolamine amidation----------------------
Serotonylation--------------------
Decanoylation----------------------
Blocked amino end----------------------
O-palmitoleoylation----------------------
S-linked Glycosylation----------------------
S-cysteinylation----------------------
Octanoylation----------------------
Thiocarboxylation----------------------
Decarboxylation----------------------
Stearoylation----------------------
Pyruvate----------------------

#, Number of PTM crosstalk proteins

PTM Type#-10-9-8-7-6-5-4-3-2-1012345678910
O-linked Glycosylation----------------------
Ubiquitination----------------------
Glutarylation----------------------
Phosphorylation----------------------
Succinylation----------------------
N-linked Glycosylation----------------------
Acetylation--------------------
Sumoylation----------------------
Sulfoxidation----------------------
Malonylation----------------------
Neddylation----------------------
Gamma-carboxyglutamic acid----------------------
Methylation----------------------
S-palmitoylation----------------------
Myristoylation----------------------
Glutathionylation----------------------
S-nitrosylation----------------------
Crotonylation----------------------
Hydroxylation----------------------
Sulfation----------------------
Butyrylation----------------------
C-linked Glycosylation----------------------
Citrullination----------------------
Deamidation----------------------
Geranylgeranylation----------------------
Lipoylation----------------------
Pyrrolidone carboxylic acid----------------------
Formation of an isopeptide bond----------------------
Farnesylation----------------------
Oxidation----------------------
GPI-anchor----------------------
Lactylation----------------------
AMPylation----------------------
Lactoylation----------------------
ADP-ribosylation----------------------
Iodination----------------------
Amidation----------------------
Deamination----------------------
Nitration----------------------
Carboxylation----------------------
Hydroxyceramide ester----------------------
Carbamidation----------------------
Sulfhydration ----------------------
N-palmitoylation----------------------
Propionylation----------------------
Biotinylation----------------------
Carboxyethylation----------------------
Phosphatidylethanolamine amidation----------------------
Serotonylation----------------------
Decanoylation--------------------
Blocked amino end----------------------
O-palmitoleoylation----------------------
S-linked Glycosylation----------------------
S-cysteinylation----------------------
Thiocarboxylation----------------------
Decarboxylation----------------------
Stearoylation----------------------
Pyruvate----------------------

#, Number of PTM crosstalk proteins

PTM Type#-10-9-8-7-6-5-4-3-2-1012345678910
O-linked Glycosylation-------------------
Ubiquitination---------------
Glutarylation----------------------
Phosphorylation--
Succinylation----------------------
N-linked Glycosylation-------------------
Acetylation---------------
Sumoylation--------------------
Sulfoxidation------------------
Malonylation----------------------
Neddylation----------------------
Gamma-carboxyglutamic acid----------------------
Methylation------------------
S-palmitoylation--------------------
Myristoylation----------------------
Glutathionylation--------------------
S-nitrosylation--------------------
Crotonylation----------------------
Hydroxylation--------------------
Sulfation--------------------
Butyrylation----------------------
C-linked Glycosylation----------------------
Citrullination----------------------
Deamidation----------------------
Geranylgeranylation----------------------
Lipoylation----------------------
Pyrrolidone carboxylic acid----------------------
Formation of an isopeptide bond----------------------
Farnesylation----------------------
GPI-anchor----------------------
Lactylation----------------------
AMPylation----------------------
Lactoylation----------------------
ADP-ribosylation----------------------
Iodination----------------------
Amidation----------------------
Deamination----------------------
Nitration----------------------
Carboxylation----------------------
Hydroxyceramide ester----------------------
Carbamidation--------------------
Sulfhydration --------------------
N-palmitoylation----------------------
Propionylation----------------------
Biotinylation----------------------
Carboxyethylation----------------------
Phosphatidylethanolamine amidation----------------------
Serotonylation----------------------
Decanoylation----------------------
Blocked amino end----------------------
O-palmitoleoylation----------------------
S-linked Glycosylation----------------------
S-cysteinylation----------------------
Octanoylation----------------------
Thiocarboxylation----------------------
Decarboxylation----------------------
Stearoylation----------------------
Pyruvate----------------------

#, Number of PTM crosstalk proteins

PTM Type#-10-9-8-7-6-5-4-3-2-1012345678910
O-linked Glycosylation
Ubiquitination
Glutarylation-
Succinylation
N-linked Glycosylation
Acetylation
Sumoylation
Sulfoxidation
Malonylation
Neddylation
Gamma-carboxyglutamic acid---------
Methylation
S-palmitoylation
Myristoylation----------
Glutathionylation
S-nitrosylation
Crotonylation-
Hydroxylation--
Sulfation-
Butyrylation-----
C-linked Glycosylation--------------
Citrullination--
Deamidation-----
Geranylgeranylation-------------
Lipoylation---------------
Pyrrolidone carboxylic acid---------
Formation of an isopeptide bond--------------
Farnesylation-------------
Oxidation--
GPI-anchor-----------------
Lactylation-
AMPylation-------------
Lactoylation-
ADP-ribosylation
Iodination--------------------
Amidation-------
Deamination--------------
Nitration---------------
Carboxylation--------------------
Hydroxyceramide ester----------------------
Carbamidation-
Sulfhydration -----------------
N-palmitoylation----------------------
Propionylation-------
Biotinylation-----------------
Carboxyethylation--------------------
Phosphatidylethanolamine amidation----------------------
Serotonylation-----------------
Decanoylation----------------------
Blocked amino end----------------------
O-palmitoleoylation----------------------
S-linked Glycosylation----------------------
S-cysteinylation----------------------
Octanoylation----------------------
Thiocarboxylation----------------------
Decarboxylation----------------------
Stearoylation-------------------
Pyruvate-----------------

#, Number of PTM crosstalk proteins

PTM Type#-10-9-8-7-6-5-4-3-2-1012345678910
O-linked Glycosylation--------------------
Ubiquitination----------------
Glutarylation---------------
Phosphorylation-------
Succinylation-----------------
N-linked Glycosylation----------------------
Acetylation------------
Sumoylation---------------
Sulfoxidation------------------
Malonylation-------------------
Neddylation----------------------
Gamma-carboxyglutamic acid----------------------
Methylation---------------
S-palmitoylation----------------------
Myristoylation----------------------
Glutathionylation----------------------
S-nitrosylation----------------------
Crotonylation----------------
Hydroxylation-------------------
Sulfation----------------------
Butyrylation-------------
C-linked Glycosylation----------------------
Citrullination--------------------
Deamidation----------------------
Geranylgeranylation----------------------
Lipoylation----------------------
Pyrrolidone carboxylic acid----------------------
Formation of an isopeptide bond----------------------
Farnesylation----------------------
Oxidation----------------------
GPI-anchor----------------------
Lactylation---------------
AMPylation----------------------
Lactoylation--------------
ADP-ribosylation----------------------
Iodination----------------------
Amidation----------------------
Deamination----------------------
Nitration----------------------
Carboxylation----------------------
Hydroxyceramide ester----------------------
Carbamidation----------------------
Sulfhydration ----------------------
N-palmitoylation----------------------
Biotinylation----------------------
Carboxyethylation----------------------
Phosphatidylethanolamine amidation----------------------
Serotonylation----------------------
Decanoylation----------------------
Blocked amino end----------------------
O-palmitoleoylation----------------------
S-linked Glycosylation----------------------
S-cysteinylation----------------------
Octanoylation----------------------
Thiocarboxylation----------------------
Decarboxylation----------------------
Stearoylation----------------------
Pyruvate----------------------

#, Number of PTM crosstalk proteins

PTM Type#-10-9-8-7-6-5-4-3-2-1012345678910
O-linked Glycosylation-
Ubiquitination
Glutarylation--------------------
Phosphorylation
Succinylation-
N-linked Glycosylation-------
Acetylation
Sumoylation---
Sulfoxidation---
Malonylation-
Neddylation------
Gamma-carboxyglutamic acid----------------------
Methylation-
S-palmitoylation------
Myristoylation--------------------
Glutathionylation--
Crotonylation----------------------
Hydroxylation--------------------
Sulfation--------------------
Butyrylation----------------------
C-linked Glycosylation----------------------
Citrullination----------------------
Deamidation-----------------
Geranylgeranylation--------------------
Lipoylation----------------------
Pyrrolidone carboxylic acid----------------------
Formation of an isopeptide bond----------------------
Farnesylation-------------------
Oxidation--------------------
GPI-anchor----------------------
Lactylation----------------------
AMPylation----------------------
Lactoylation----------------------
ADP-ribosylation-------------------
Iodination----------------------
Amidation----------------------
Deamination----------------------
Nitration----------------------
Carboxylation----------------------
Hydroxyceramide ester----------------------
Carbamidation----------------------
Sulfhydration --------------------
N-palmitoylation----------------------
Propionylation----------------------
Biotinylation----------------------
Carboxyethylation----------------------
Phosphatidylethanolamine amidation----------------------
Serotonylation----------------------
Decanoylation----------------------
Blocked amino end----------------------
O-palmitoleoylation----------------------
S-linked Glycosylation----------------------
S-cysteinylation----------------------
Octanoylation----------------------
Thiocarboxylation----------------------
Decarboxylation----------------------
Stearoylation----------------------
Pyruvate----------------------

#, Number of PTM crosstalk proteins

PTM Type#-10-9-8-7-6-5-4-3-2-1012345678910
O-linked Glycosylation----
Ubiquitination
Glutarylation--------------------
Phosphorylation
Succinylation--
N-linked Glycosylation-------
Acetylation
Sumoylation----
Sulfoxidation--
Malonylation--
Neddylation---------
Gamma-carboxyglutamic acid----------------------
Methylation
Myristoylation-------------
Glutathionylation-----
S-nitrosylation------
Crotonylation----------------------
Hydroxylation----------------------
Sulfation----------------------
Butyrylation----------------------
C-linked Glycosylation----------------------
Citrullination----------------------
Deamidation-----------------
Geranylgeranylation----------------
Lipoylation----------------------
Pyrrolidone carboxylic acid----------------------
Formation of an isopeptide bond----------------------
Farnesylation---------------
Oxidation--------------------
GPI-anchor----------------------
Lactylation----------------------
AMPylation----------------------
Lactoylation----------------------
ADP-ribosylation----------------------
Iodination----------------------
Amidation----------------------
Deamination----------------------
Nitration----------------------
Carboxylation----------------------
Hydroxyceramide ester----------------------
Carbamidation--------------------
Sulfhydration ----------------------
N-palmitoylation----------------------
Propionylation----------------------
Biotinylation----------------------
Carboxyethylation----------------------
Phosphatidylethanolamine amidation----------------------
Serotonylation----------------------
Decanoylation----------------------
Blocked amino end----------------------
O-palmitoleoylation----------------------
S-linked Glycosylation----------------------
S-cysteinylation----------------------
Octanoylation----------------------
Thiocarboxylation----------------------
Decarboxylation----------------------
Stearoylation--------------------
Pyruvate----------------------

#, Number of PTM crosstalk proteins

PTM Type#-10-9-8-7-6-5-4-3-2-1012345678910
O-linked Glycosylation--------------------
Ubiquitination-------------------
Glutarylation--------------------
Phosphorylation-----------------
Succinylation--------------------
N-linked Glycosylation----------------------
Acetylation-----------------
Sumoylation--------------------
Sulfoxidation----------------------
Malonylation----------------------
Neddylation----------------------
Gamma-carboxyglutamic acid----------------------
Methylation----------------
S-palmitoylation----------------------
Myristoylation----------------------
Glutathionylation----------------------
S-nitrosylation----------------------
Crotonylation-------------------
Hydroxylation----------------------
Sulfation----------------------
Butyrylation--------------------
C-linked Glycosylation----------------------
Citrullination-------------------
Deamidation----------------------
Geranylgeranylation----------------------
Lipoylation----------------------
Pyrrolidone carboxylic acid----------------------
Formation of an isopeptide bond--------------------
Farnesylation----------------------
Oxidation----------------------
GPI-anchor----------------------
Lactylation-------------------
AMPylation----------------------
Lactoylation--------------------
ADP-ribosylation--------------------
Iodination----------------------
Amidation----------------------
Deamination--------------------
Nitration----------------------
Carboxylation----------------------
Hydroxyceramide ester----------------------
Carbamidation----------------------
Sulfhydration ----------------------
N-palmitoylation----------------------
Propionylation----------------------
Biotinylation----------------------
Carboxyethylation----------------------
Phosphatidylethanolamine amidation----------------------
Decanoylation----------------------
Blocked amino end----------------------
O-palmitoleoylation----------------------
S-linked Glycosylation----------------------
S-cysteinylation----------------------
Octanoylation----------------------
Thiocarboxylation----------------------
Decarboxylation----------------------
Stearoylation----------------------
Pyruvate----------------------

#, Number of PTM crosstalk proteins

PTM Type#-10-9-8-7-6-5-4-3-2-1012345678910
O-linked Glycosylation---
Ubiquitination
Glutarylation-----
Phosphorylation
N-linked Glycosylation----------------
Acetylation
Sumoylation-
Sulfoxidation
Malonylation
Neddylation--------
Gamma-carboxyglutamic acid----------------------
Methylation-
S-palmitoylation--
Myristoylation----------------------
Glutathionylation--
S-nitrosylation-
Crotonylation----------
Hydroxylation---------------
Sulfation----------------------
Butyrylation--------------
C-linked Glycosylation----------------------
Citrullination------------------
Deamidation--------------------
Geranylgeranylation----------------------
Lipoylation----------------------
Pyrrolidone carboxylic acid----------------------
Formation of an isopeptide bond--------------------
Farnesylation----------------------
Oxidation----------------------
GPI-anchor----------------------
Lactylation--------------
AMPylation----------------------
Lactoylation------------
ADP-ribosylation-----------------
Iodination----------------------
Amidation----------------------
Deamination--------------------
Nitration--------------------
Carboxylation----------------------
Hydroxyceramide ester----------------------
Carbamidation----------------------
Sulfhydration ----------------------
N-palmitoylation----------------------
Propionylation-----------------
Biotinylation----------------------
Carboxyethylation----------------------
Phosphatidylethanolamine amidation----------------------
Serotonylation--------------------
Decanoylation----------------------
Blocked amino end----------------------
O-palmitoleoylation----------------------
S-linked Glycosylation----------------------
S-cysteinylation----------------------
Octanoylation----------------------
Thiocarboxylation----------------------
Decarboxylation----------------------
Stearoylation----------------------
Pyruvate----------------------

#, Number of PTM crosstalk proteins

PTM Type#-10-9-8-7-6-5-4-3-2-1012345678910
O-linked Glycosylation--------
Ubiquitination-------------------
Glutarylation----------------------
Phosphorylation-
Succinylation----------------------
N-linked Glycosylation------
Acetylation-------------------
Sumoylation----------------------
Sulfoxidation----------------------
Malonylation----------------------
Neddylation----------------------
Gamma-carboxyglutamic acid----------------------
Methylation----------------------
S-palmitoylation----------------------
Myristoylation----------------------
Glutathionylation--------------------
S-nitrosylation--------------------
Crotonylation----------------------
Hydroxylation----------------------
Butyrylation----------------------
C-linked Glycosylation----------------------
Citrullination----------------------
Deamidation----------------------
Geranylgeranylation----------------------
Lipoylation----------------------
Pyrrolidone carboxylic acid----------------
Formation of an isopeptide bond----------------------
Farnesylation----------------------
Oxidation--------------------
GPI-anchor----------------------
Lactylation----------------------
AMPylation----------------------
Lactoylation----------------------
ADP-ribosylation----------------------
Iodination----------------------
Amidation-------------------
Deamination----------------------
Nitration----------------------
Carboxylation----------------------
Hydroxyceramide ester----------------------
Carbamidation----------------------
Sulfhydration --------------------
N-palmitoylation----------------------
Propionylation----------------------
Biotinylation----------------------
Carboxyethylation----------------------
Phosphatidylethanolamine amidation----------------------
Serotonylation----------------------
Decanoylation----------------------
Blocked amino end----------------------
O-palmitoleoylation----------------------
S-linked Glycosylation----------------------
S-cysteinylation----------------------
Octanoylation----------------------
Thiocarboxylation----------------------
Decarboxylation----------------------
Stearoylation----------------------
Pyruvate----------------------

#, Number of PTM crosstalk proteins

PTM Type#-10-9-8-7-6-5-4-3-2-1012345678910
O-linked Glycosylation
Ubiquitination
Glutarylation---------
Phosphorylation
Succinylation
N-linked Glycosylation-----------
Acetylation
Sumoylation-
Malonylation-
Neddylation
Gamma-carboxyglutamic acid----------------------
Methylation-
S-palmitoylation--
Myristoylation----------------------
Glutathionylation-
S-nitrosylation---
Crotonylation----------------------
Hydroxylation-----------------
Sulfation----------------------
Butyrylation------------------
C-linked Glycosylation----------------------
Citrullination----------------------
Deamidation--------------------
Geranylgeranylation----------------------
Lipoylation----------------------
Pyrrolidone carboxylic acid----------------------
Formation of an isopeptide bond----------------------
Farnesylation----------------------
Oxidation------------------
GPI-anchor----------------------
Lactylation----------------------
AMPylation----------------------
Lactoylation-------------------
ADP-ribosylation--------------------
Iodination----------------------
Amidation----------------------
Deamination--------------------
Nitration----------------------
Carboxylation----------------------
Hydroxyceramide ester----------------------
Carbamidation--------------------
Sulfhydration ----------------------
N-palmitoylation----------------------
Propionylation------------------
Biotinylation----------------------
Carboxyethylation----------------------
Phosphatidylethanolamine amidation----------------------
Serotonylation----------------------
Decanoylation----------------------
Blocked amino end----------------------
O-palmitoleoylation----------------------
S-linked Glycosylation----------------------
S-cysteinylation----------------------
Octanoylation----------------------
Thiocarboxylation----------------------
Decarboxylation----------------------
Stearoylation----------------------
Pyruvate----------------------

#, Number of PTM crosstalk proteins

PTM Type#-10-9-8-7-6-5-4-3-2-1012345678910
O-linked Glycosylation-
Ubiquitination
Glutarylation-------
Phosphorylation
Succinylation-
N-linked Glycosylation-----------------
Acetylation
Sulfoxidation-
Malonylation
Neddylation-
Gamma-carboxyglutamic acid----------------------
Methylation
S-palmitoylation----
Myristoylation----------------------
Glutathionylation---
S-nitrosylation---
Crotonylation-----
Hydroxylation--------------
Sulfation----------------------
Butyrylation---------
C-linked Glycosylation----------------------
Citrullination--------------
Deamidation-----------------
Geranylgeranylation----------------------
Lipoylation----------------------
Pyrrolidone carboxylic acid----------------------
Formation of an isopeptide bond--------------------
Farnesylation----------------------
Oxidation--------------------
GPI-anchor----------------------
Lactylation------
AMPylation----------------------
Lactoylation------
ADP-ribosylation----------
Iodination----------------------
Amidation----------------------
Deamination--------------------
Nitration----------------------
Carboxylation----------------------
Hydroxyceramide ester----------------------
Carbamidation--------------------
Sulfhydration ----------------------
N-palmitoylation----------------------
Propionylation---------------
Biotinylation----------------------
Carboxyethylation----------------------
Phosphatidylethanolamine amidation----------------------
Serotonylation--------------------
Decanoylation----------------------
Blocked amino end----------------------
O-palmitoleoylation----------------------
S-linked Glycosylation----------------------
S-cysteinylation----------------------
Octanoylation----------------------
Thiocarboxylation----------------------
Decarboxylation----------------------
Stearoylation----------------------
Pyruvate----------------------

#, Number of PTM crosstalk proteins

PTM Type#-10-9-8-7-6-5-4-3-2-1012345678910
O-linked Glycosylation
Glutarylation-
Phosphorylation
Succinylation
N-linked Glycosylation
Acetylation
Sumoylation
Sulfoxidation
Malonylation
Neddylation
Gamma-carboxyglutamic acid----------------------
Methylation
S-palmitoylation
Myristoylation---------------
Glutathionylation
S-nitrosylation
Crotonylation
Hydroxylation
Sulfation-------------------
Butyrylation-------
C-linked Glycosylation----------------------
Citrullination--------------
Deamidation---------
Geranylgeranylation----------------
Lipoylation--------------------
Pyrrolidone carboxylic acid------------------
Formation of an isopeptide bond-------------------
Farnesylation------------------
Oxidation---------------
GPI-anchor----------------------
Lactylation
AMPylation----------------------
Lactoylation--
ADP-ribosylation--
Iodination----------------------
Amidation----------------------
Deamination---------
Nitration--------------
Carboxylation----------------------
Hydroxyceramide ester----------------------
Carbamidation----------------
Sulfhydration ----------------------
N-palmitoylation----------------------
Propionylation----------------
Biotinylation----------------------
Carboxyethylation----------------------
Phosphatidylethanolamine amidation-------------------
Serotonylation-------------------
Decanoylation----------------------
Blocked amino end----------------------
O-palmitoleoylation----------------------
S-linked Glycosylation----------------------
S-cysteinylation----------------------
Octanoylation----------------------
Thiocarboxylation----------------------
Decarboxylation----------------------
Stearoylation----------------------
Pyruvate----------------------

TOP