| UniProt ID | DAL81_YEAST | |
|---|---|---|
| UniProt AC | P21657 | |
| Protein Name | Transcriptional activator protein DAL81 | |
| Gene Name | DAL81 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 970 | |
| Subcellular Localization | Nucleus. | |
| Protein Description | Positive regulation of genes required for catabolism of GABA (UGA4, UGA1, and UGA2), urea (DUR1 and DUR2), arginine and allantoin.. | |
| Protein Sequence | MDPHQSPADNAASPTKSVKATTKNSSTNNNVNSNNSNNNSNHDILNFNDNYTTILQHLANDHPNILREKGGSQQQQHQQQQQQQQQQQQQQQQQSLDTLLHHYQSLLSKSDNAIAFDDNVSNSADHNGSNSNNNNNNNDISSPGNLMGSCNQCRLKKTKCNYFPDLGNCLECETSRTKCTFSIAPNYLKRTSSGANNNMPTSSNSKRMKNFEDYSNRLPSSMLYRHQQQQQQQQQQQRIQYPRSSFFVGPASVFDLNLTKHVRLDNVDQIQLSKTLSLRKVSPTAQFILQDDFDTTLHSKQEYEVDLVENLVHPHGHLLVEIFFKLIHPFLPILHERVFLEKYSRSYRELTAPLLASIYSLALQYWDFHPALLGFPKPDVTAQLNNIALETFYARVGRPKLSIIQTGLLILQCRSECHNNWVLCSSVVALAEELGLGVECNDWKLPKWEKDLRKRLAWAVWLMDKWCALNEGRQSHLILGRNWMIKLLNFDDFPLNSPTILNSLQNDQSGSSPSSSNDVKNHQIAFGNLPIFNINPTLEDFKNGTLMFQQMVSLSIILGEIMDTFYTQGSMTINKSIEQVLKLAKPLQLKLREWYHSLPKNLSMSYATPQKLNSNSTLTLAYFATEITLHRKIICALNPQTPKELVQVCRTAARTRLVAAIEFIRDLKNEHINAFWYNCSTGNLMLIGTFAALLYVTSATKEEAMIFRDYVRNYTWVLKIGSKYFDKLSNALNNMHLLFAQIPGLLTDEPVVVSPNSNINSVNPQRSGVQSQIPIQFNVGSPAMTEQGSPLNQWKNLPQEILQQLNSFPNGTTSTTTPVNPTSRQTQLESQGSPAINSANNNSNNTPLPFAPNKSSKKTSQSSPNVTPSHMSRHPPSNTSSPRVNSSTNVNSNTQMNASPLTSINETRQESGDAADEKTAGRERTANEESSTELKDDNPNSNQETSATGNQTIKMNDDKNVTINTRETPL | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
|
|
||
* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 6 | Phosphorylation | --MDPHQSPADNAAS --CCCCCCCCCCCCC | 21.01 | 22369663 | |
| 13 | Phosphorylation | SPADNAASPTKSVKA CCCCCCCCCCCCCEE | 30.60 | 22369663 | |
| 15 | Phosphorylation | ADNAASPTKSVKATT CCCCCCCCCCCEEEC | 33.19 | 22369663 | |
| 17 | Phosphorylation | NAASPTKSVKATTKN CCCCCCCCCEEECCC | 31.18 | 23607784 | |
| 191 | Phosphorylation | APNYLKRTSSGANNN CCCCHHCCCCCCCCC | 26.17 | 17563356 | |
| 192 | Phosphorylation | PNYLKRTSSGANNNM CCCHHCCCCCCCCCC | 30.70 | 24909858 | |
| 193 | Phosphorylation | NYLKRTSSGANNNMP CCHHCCCCCCCCCCC | 41.11 | 25521595 | |
| 201 | Phosphorylation | GANNNMPTSSNSKRM CCCCCCCCCCCCHHC | 33.74 | 19823750 | |
| 202 | Phosphorylation | ANNNMPTSSNSKRMK CCCCCCCCCCCHHCC | 22.96 | 19823750 | |
| 203 | Phosphorylation | NNNMPTSSNSKRMKN CCCCCCCCCCHHCCC | 47.83 | 21440633 | |
| 205 | Phosphorylation | NMPTSSNSKRMKNFE CCCCCCCCHHCCCHH | 24.48 | 17563356 | |
| 209 | Acetylation | SSNSKRMKNFEDYSN CCCCHHCCCHHHHHH | 63.62 | 25381059 | |
| 220 | Phosphorylation | DYSNRLPSSMLYRHQ HHHHHCCHHHHHHHH | 32.73 | 30377154 | |
| 343 | Phosphorylation | ERVFLEKYSRSYREL HHHHHHHHCCHHHHH | 10.43 | 27017623 | |
| 344 | Phosphorylation | RVFLEKYSRSYRELT HHHHHHHCCHHHHHH | 26.31 | 27017623 | |
| 509 | Phosphorylation | NSLQNDQSGSSPSSS HHHCCCCCCCCCCCC | 43.43 | 21551504 | |
| 511 | Phosphorylation | LQNDQSGSSPSSSND HCCCCCCCCCCCCHH | 44.30 | 21551504 | |
| 512 | Phosphorylation | QNDQSGSSPSSSNDV CCCCCCCCCCCCHHC | 32.12 | 21440633 | |
| 514 | Phosphorylation | DQSGSSPSSSNDVKN CCCCCCCCCCHHCCC | 48.63 | 21551504 | |
| 515 | Phosphorylation | QSGSSPSSSNDVKNH CCCCCCCCCHHCCCC | 36.22 | 21551504 | |
| 516 | Phosphorylation | SGSSPSSSNDVKNHQ CCCCCCCCHHCCCCE | 41.19 | 21551504 | |
| 781 | Phosphorylation | PIQFNVGSPAMTEQG CEEEECCCCCCCCCC | 12.76 | 21440633 | |
| 785 | Phosphorylation | NVGSPAMTEQGSPLN ECCCCCCCCCCCCHH | 27.54 | 21440633 | |
| 789 | Phosphorylation | PAMTEQGSPLNQWKN CCCCCCCCCHHHHCC | 26.38 | 28152593 | |
| 830 | Phosphorylation | SRQTQLESQGSPAIN CCCHHHHHCCCCCCC | 48.73 | 23749301 | |
| 833 | Phosphorylation | TQLESQGSPAINSAN HHHHHCCCCCCCCCC | 11.97 | 25752575 | |
| 838 | Phosphorylation | QGSPAINSANNNSNN CCCCCCCCCCCCCCC | 26.68 | 23749301 | |
| 843 | Phosphorylation | INSANNNSNNTPLPF CCCCCCCCCCCCCCC | 33.31 | 30377154 | |
| 859 | Phosphorylation | PNKSSKKTSQSSPNV CCCCCCCCCCCCCCC | 35.42 | 22369663 | |
| 860 | Phosphorylation | NKSSKKTSQSSPNVT CCCCCCCCCCCCCCC | 36.62 | 22369663 | |
| 862 | Phosphorylation | SSKKTSQSSPNVTPS CCCCCCCCCCCCCHH | 47.75 | 22369663 | |
| 863 | Phosphorylation | SKKTSQSSPNVTPSH CCCCCCCCCCCCHHH | 16.92 | 22369663 | |
| 867 | Phosphorylation | SQSSPNVTPSHMSRH CCCCCCCCHHHHCCC | 26.22 | 22369663 | |
| 869 | Phosphorylation | SSPNVTPSHMSRHPP CCCCCCHHHHCCCCC | 23.58 | 22369663 | |
| 872 | Phosphorylation | NVTPSHMSRHPPSNT CCCHHHHCCCCCCCC | 23.24 | 22369663 | |
| 877 | Phosphorylation | HMSRHPPSNTSSPRV HHCCCCCCCCCCCCC | 58.13 | 17563356 | |
| 879 | Phosphorylation | SRHPPSNTSSPRVNS CCCCCCCCCCCCCCC | 34.61 | 28889911 | |
| 880 | Phosphorylation | RHPPSNTSSPRVNSS CCCCCCCCCCCCCCC | 42.46 | 28889911 | |
| 881 | Phosphorylation | HPPSNTSSPRVNSST CCCCCCCCCCCCCCC | 18.06 | 17563356 | |
| 886 | Phosphorylation | TSSPRVNSSTNVNSN CCCCCCCCCCCCCCC | 35.36 | 23749301 | |
| 887 | Phosphorylation | SSPRVNSSTNVNSNT CCCCCCCCCCCCCCC | 20.85 | 23749301 | |
| 888 | Phosphorylation | SPRVNSSTNVNSNTQ CCCCCCCCCCCCCCC | 42.90 | 27017623 | |
| 892 | Phosphorylation | NSSTNVNSNTQMNAS CCCCCCCCCCCCCCC | 36.65 | 28889911 | |
| 899 | Phosphorylation | SNTQMNASPLTSINE CCCCCCCCCCCCHHH | 18.55 | 25752575 | |
| 903 | Phosphorylation | MNASPLTSINETRQE CCCCCCCCHHHHHHH | 30.97 | 27017623 | |
| 907 | Phosphorylation | PLTSINETRQESGDA CCCCHHHHHHHHCCC | 32.91 | 19779198 | |
| 919 | Phosphorylation | GDAADEKTAGRERTA CCCCCHHHHCCCCCC | 32.09 | 24961812 | |
| 925 | Phosphorylation | KTAGRERTANEESST HHHCCCCCCCCCCCC | 29.14 | 22369663 | |
| 930 | Phosphorylation | ERTANEESSTELKDD CCCCCCCCCCCCCCC | 36.06 | 22369663 | |
| 931 | Phosphorylation | RTANEESSTELKDDN CCCCCCCCCCCCCCC | 29.22 | 22369663 | |
| 932 | Phosphorylation | TANEESSTELKDDNP CCCCCCCCCCCCCCC | 55.40 | 22369663 | |
| 941 | Phosphorylation | LKDDNPNSNQETSAT CCCCCCCCCCCCCCC | 40.94 | 22369663 | |
| 945 | Phosphorylation | NPNSNQETSATGNQT CCCCCCCCCCCCCCE | 17.56 | 22369663 | |
| 946 | Phosphorylation | PNSNQETSATGNQTI CCCCCCCCCCCCCEE | 24.07 | 22369663 | |
| 948 | Phosphorylation | SNQETSATGNQTIKM CCCCCCCCCCCEEEC | 36.11 | 22369663 | |
| 952 | Phosphorylation | TSATGNQTIKMNDDK CCCCCCCEEECCCCC | 26.94 | 22369663 | |
| 962 | Phosphorylation | MNDDKNVTINTRETP CCCCCCEEEEEECCC | 20.22 | 28889911 | |
| 965 | Phosphorylation | DKNVTINTRETPL-- CCCEEEEEECCCC-- | 26.49 | 23749301 | |
| 968 | Phosphorylation | VTINTRETPL----- EEEEEECCCC----- | 26.97 | 22369663 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of DAL81_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of DAL81_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of DAL81_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
loading...
| Phosphorylation | |
| Reference | PubMed |
| "A multidimensional chromatography technology for in-depthphosphoproteome analysis."; Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.; Mol. Cell. Proteomics 7:1389-1396(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-863, AND MASSSPECTROMETRY. | |
| "Proteome-wide identification of in vivo targets of DNA damagecheckpoint kinases."; Smolka M.B., Albuquerque C.P., Chen S.H., Zhou H.; Proc. Natl. Acad. Sci. U.S.A. 104:10364-10369(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-191; SER-192; SER-193;SER-205; SER-863; SER-877 AND SER-881, AND MASS SPECTROMETRY. | |
| "Quantitative phosphoproteomics applied to the yeast pheromonesignaling pathway."; Gruhler A., Olsen J.V., Mohammed S., Mortensen P., Faergeman N.J.,Mann M., Jensen O.N.; Mol. Cell. Proteomics 4:310-327(2005). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-968, AND MASSSPECTROMETRY. | |
