NRG1_YEAST - dbPTM
NRG1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID NRG1_YEAST
UniProt AC Q03125
Protein Name Transcriptional regulator NRG1
Gene Name NRG1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 231
Subcellular Localization Nucleus .
Protein Description Transcriptional repressor involved in regulation of glucose repression. Binds to UAS-1 in the STA1 promoter..
Protein Sequence MFYPYNYSNLNVSTMPALPGISAFDGMQDEENVEISPERKYQTLLPVLTNSHVVENELKHKLNKTAFDFRYQTKSENGSEKWEPKYLITPNLQTRSVSFDNSSVQYNSDSSEKSSLSQLTCNSSIIQQPENGIVSNDAYNKMANSRYSLKTRKQRTDPRNTLSDEEDLEQRRKYICKICARGFTTSGHLARHNRIHTGEKNHCCPYKGCTQRFSRHDNCLQHYRTHLKKGQ
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
7Phosphorylation-MFYPYNYSNLNVST
-CCCCCCCCCCCCCC		7.9730377154
8PhosphorylationMFYPYNYSNLNVSTM
CCCCCCCCCCCCCCC		31.0730377154
14PhosphorylationYSNLNVSTMPALPGI
CCCCCCCCCCCCCCC		23.9230377154
36PhosphorylationDEENVEISPERKYQT
CCCCCCCCHHHHHHH		13.7530377154
96PhosphorylationTPNLQTRSVSFDNSS
CCCCCEEEEEECCCC		26.0422369663
98PhosphorylationNLQTRSVSFDNSSVQ
CCCEEEEEECCCCEE		28.2922369663
102PhosphorylationRSVSFDNSSVQYNSD
EEEEECCCCEEECCC		33.4621551504
103PhosphorylationSVSFDNSSVQYNSDS
EEEECCCCEEECCCC		21.3522369663
106PhosphorylationFDNSSVQYNSDSSEK
ECCCCEEECCCCCCC		17.9322369663
108PhosphorylationNSSVQYNSDSSEKSS
CCCEEECCCCCCCCC		33.6622369663
110PhosphorylationSVQYNSDSSEKSSLS
CEEECCCCCCCCCHH		39.9722369663
111PhosphorylationVQYNSDSSEKSSLSQ
EEECCCCCCCCCHHH		54.7722369663
161PhosphorylationQRTDPRNTLSDEEDL
CCCCCCCCCCCHHHH		28.9922890988
163PhosphorylationTDPRNTLSDEEDLEQ
CCCCCCCCCHHHHHH		40.7222369663
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of NRG1_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of NRG1_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of NRG1_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
SNF1_YEASTSNF1physical
11404322
CYC8_YEASTCYC8physical
10022891
PACC_YEASTRIM101physical
16024810
NRG2_YEASTNRG2genetic
12024013
PACC_YEASTRIM101genetic
16024810
CSK21_YEASTCKA1physical
16554755
LTE1_YEASTLTE1genetic
20093466
YD444_YEASTYDR444Wgenetic
20093466
ATC1_YEASTPMR1genetic
20093466
PALF_YEASTRIM8genetic
20093466
MGA1_YEASTMGA1genetic
20093466
LIN1_YEASTLIN1genetic
20093466
YHY2_YEASTYHR182Wgenetic
20093466
VHS2_YEASTVHS2genetic
20093466
SIM1_YEASTSIM1genetic
20093466
POG1_YEASTPOG1genetic
20093466
COPE_YEASTSEC28genetic
20093466
ECM25_YEASTECM25genetic
20093466
YJQ3_YEASTYJL163Cgenetic
20093466
ASF1_YEASTASF1genetic
20093466
IME2_YEASTIME2genetic
20093466
BTN1_YEASTYHC3genetic
20093466
CYC1_YEASTCYC1genetic
20093466
YKH5_YEASTYKL075Cgenetic
20093466
BYE1_YEASTBYE1genetic
20093466
FOX2_YEASTFOX2genetic
20093466
YCT1_YEASTYCT1genetic
20093466
FPS1_YEASTFPS1genetic
20093466
KNS1_YEASTKNS1genetic
20093466
ACE2_YEASTACE2genetic
20093466
CHS5_YEASTCHS5genetic
20093466
SHH3_YEASTSHH3genetic
20093466
APJ1_YEASTAPJ1genetic
20093466
BOP3_YEASTBOP3genetic
20093466
MNT4_YEASTMNT4genetic
20093466
FRE7_YEASTFRE7genetic
20093466
SKM1_YEASTSKM1genetic
20093466
INO4_YEASTINO4genetic
20093466
NBA1_YEASTNBA1genetic
20093466
HST1_YEASTHST1genetic
20093466
NTH2_YEASTNTG2genetic
20093466
ESC8_YEASTESC8genetic
20093466
ROD1_YEASTROD1genetic
20093466
SFL1_YEASTSFL1genetic
20093466
ULS1_YEASTULS1genetic
20093466
ENV9_YEASTENV9genetic
20093466
SRL1_YEASTSRL1genetic
20093466
PALA_YEASTRIM20genetic
20093466
HUA2_YEASTHUA2genetic
20093466
MPD1_YEASTMPD1genetic
20093466
ISW2_YEASTISW2genetic
20093466
SNC2_YEASTSNC2genetic
20093466
SNX3_YEASTSNX3genetic
20093466
YP245_YEASTYPL245Wgenetic
20093466
ENV7_YEASTENV7genetic
20093466
FLC1_YEASTFLC1genetic
20093466
YP199_YEASTYPL199Cgenetic
20093466
MRN1_YEASTMRN1genetic
20093466
PPQ1_YEASTPPQ1genetic
20093466
PRM4_YEASTPRM4genetic
20093466
KIP2_YEASTKIP2genetic
20093466
YP150_YEASTYPL150Wgenetic
20093466
POC4_YEASTPOC4genetic
20093466
YP107_YEASTYPL107Wgenetic
20093466
LPE10_YEASTMFM1genetic
20093466
MRX11_YEASTYPL041Cgenetic
20093466
PMA2_YEASTPMA2genetic
20093466
VTC3_YEASTVTC3genetic
20093466
CTF19_YEASTCTF19genetic
20093466
YP014_YEASTYPL014Wgenetic
20093466
YMC1_YEASTYMC1genetic
20093466
RGC1_YEASTRGC1genetic
20093466
MTNA_YEASTMRI1genetic
20093466
CTF4_YEASTCTF4genetic
20093466
KAR3_YEASTKAR3genetic
20093466
SUE1_YEASTSUE1genetic
20093466
HAL5_YEASTHAL5genetic
20206679
NRG2_YEASTNRG2genetic
20402793
URE2_YEASTURE2genetic
20959818
H4_YEASTHHF1genetic
20959818
SSN3_YEASTSSN3genetic
20959818
CBF1_YEASTCBF1genetic
20959818
MGA2_YEASTMGA2genetic
20959818
REI1_YEASTREI1genetic
21127252
RTG3_YEASTRTG3genetic
21127252
PRR2_YEASTPRR2genetic
21127252
YP150_YEASTYPL150Wgenetic
22282571
NRG2_YEASTNRG2genetic
25266663
XRN1_YEASTXRN1genetic
24119399
ARP6_YEASTARP6genetic
27708008
SHH3_YEASTSHH3genetic
27708008
ENB1_YEASTENB1genetic
27708008
MSA1_YEASTMSA1genetic
27708008
SRL1_YEASTSRL1genetic
27708008
YO292_YEASTYOR292Cgenetic
27708008
SNX3_YEASTSNX3genetic
27708008
YP014_YEASTYPL014Wgenetic
27708008
POC4_YEASTPOC4genetic
27708008
PRP6_YEASTPRP6genetic
27708008
MED8_YEASTMED8genetic
27708008
TIM22_YEASTTIM22genetic
27708008
RPB7_YEASTRPB7genetic
27708008
GPI19_YEASTGPI19genetic
27708008
PANK_YEASTCAB1genetic
27708008
COG3_YEASTCOG3genetic
27708008
CDC20_YEASTCDC20genetic
27708008
BRR6_YEASTBRR6genetic
27708008
BRL1_YEASTBRL1genetic
27708008
YKT6_YEASTYKT6genetic
27708008
SED5_YEASTSED5genetic
27708008
BOS1_YEASTBOS1genetic
27708008
SEC22_YEASTSEC22genetic
27708008
STT4_YEASTSTT4genetic
27708008
RPB2_YEASTRPB2genetic
27708008
MED4_YEASTMED4genetic
27708008
GPI2_YEASTGPI2genetic
27708008
SEC62_YEASTSEC62genetic
27708008
THRC_YEASTTHR4genetic
27708008
RLA4_YEASTRPP2Bgenetic
27708008
CP56_YEASTDIT2genetic
27708008
YD444_YEASTYDR444Wgenetic
27708008
ATC1_YEASTPMR1genetic
27708008
FKS2_YEASTGSC2genetic
27708008
ASK10_YEASTASK10genetic
27708008
GOSR1_YEASTGOS1genetic
27708008
LIN1_YEASTLIN1genetic
27708008
POG1_YEASTPOG1genetic
27708008
VHS2_YEASTVHS2genetic
27708008
FLO11_YEASTFLO11genetic
27708008
BTN1_YEASTYHC3genetic
27708008
ASF1_YEASTASF1genetic
27708008
ECM25_YEASTECM25genetic
27708008
ELM1_YEASTELM1genetic
27708008
FPS1_YEASTFPS1genetic
27708008
YCT1_YEASTYCT1genetic
27708008
ENV10_YEASTENV10genetic
27708008
AVL9_YEASTAVL9genetic
27708008
ACE2_YEASTACE2genetic
27708008
MAC1_YEASTMAC1genetic
27708008
MNT4_YEASTMNT4genetic
27708008
INO4_YEASTINO4genetic
27708008
SKM1_YEASTSKM1genetic
27708008
SFL1_YEASTSFL1genetic
27708008
HUA2_YEASTHUA2genetic
27708008
KIP2_YEASTKIP2genetic
27708008
DAP1_YEASTDAP1genetic
27708008
YMC1_YEASTYMC1genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of NRG1_YEAST

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Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"A multidimensional chromatography technology for in-depthphosphoproteome analysis.";
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.;
Mol. Cell. Proteomics 7:1389-1396(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-163, AND MASSSPECTROMETRY.

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