| UniProt ID | POC4_YEAST | |
|---|---|---|
| UniProt AC | Q12245 | |
| Protein Name | Proteasome chaperone 4 | |
| Gene Name | POC4 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 148 | |
| Subcellular Localization | Cytoplasm . | |
| Protein Description | Involved in 20S proteasome assembly, facilitating the alpha-ring formation. Involved in maintenance of telomere length.. | |
| Protein Sequence | MLVKTISRTIESESGFLQPTLDVIATLPADDRSKKIPISLVVGFKQEASLNSSSSLSCYYYAIPLMRDRHINLKSGGSNVVGIPLLDTKDDRIRDMARHMATIISERFNRPCYVTWSSLPSEDPSMLVANHLYILKKCLDLLKTELGE | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 5 | Phosphorylation | ---MLVKTISRTIES ---CCEEECCCHHHC | 19.39 | 21440633 | |
| 49 | Phosphorylation | VGFKQEASLNSSSSL EEECCEECCCCCCCC | 27.60 | 22890988 | |
| 52 | Phosphorylation | KQEASLNSSSSLSCY CCEECCCCCCCCHHE | 36.57 | 22890988 | |
| 53 | Phosphorylation | QEASLNSSSSLSCYY CEECCCCCCCCHHEE | 23.91 | 22890988 | |
| 54 | Phosphorylation | EASLNSSSSLSCYYY EECCCCCCCCHHEEE | 34.81 | 22890988 | |
| 55 | Phosphorylation | ASLNSSSSLSCYYYA ECCCCCCCCHHEEEE | 26.67 | 22890988 | |
| 57 | Phosphorylation | LNSSSSLSCYYYAIP CCCCCCCHHEEEEHH | 11.30 | 22890988 | |
| 59 | Phosphorylation | SSSSLSCYYYAIPLM CCCCCHHEEEEHHHH | 8.99 | 22890988 | |
| 60 | Phosphorylation | SSSLSCYYYAIPLMR CCCCHHEEEEHHHHH | 7.25 | 22890988 | |
| 61 | Phosphorylation | SSLSCYYYAIPLMRD CCCHHEEEEHHHHHC | 3.30 | 22890988 | |
| 89 | Acetylation | GIPLLDTKDDRIRDM CEEECCCCCHHHHHH | 58.25 | 24489116 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of POC4_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of POC4_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of POC4_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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