ATIF_YEAST - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ATIF_YEAST
• UniProt AC: P01097
• Protein Name: ATPase inhibitor, mitochondrial
• Gene Name: INH1
• Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
• Sequence Length: 85
• Subcellular Localization: Mitochondrion.
• Protein Description: Forms a one-to-one complex with ATPase to inhibit the enzyme activity completely..
• Protein Sequence: MLPRSALARSLQLQRGVAARFYSEGSTGTPRGSGSEDSFVKRERATEDFFVRQREKEQLRHLKEQLEKQRKKIDSLENKIDSMTK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
23	Phosphorylation	GVAARFYSEGSTGTP CCHHHHHCCCCCCCC	32.54	22369663
29	Phosphorylation	YSEGSTGTPRGSGSE HCCCCCCCCCCCCCC	15.20	27017623
33	Phosphorylation	STGTPRGSGSEDSFV CCCCCCCCCCCCCHH	40.19	30377154
35	Phosphorylation	GTPRGSGSEDSFVKR CCCCCCCCCCCHHCH	39.67	24909858
38	Phosphorylation	RGSGSEDSFVKRERA CCCCCCCCHHCHHHH	28.08	30377154
41	Succinylation	GSEDSFVKRERATED CCCCCHHCHHHHCHH	46.67	23954790
56	Succinylation	FFVRQREKEQLRHLK HHHHHHHHHHHHHHH	53.61	23954790
63	Acetylation	KEQLRHLKEQLEKQR HHHHHHHHHHHHHHH	36.97	25381059
68	Acetylation	HLKEQLEKQRKKIDS HHHHHHHHHHHHHHH	65.09	25381059
75	Phosphorylation	KQRKKIDSLENKIDS HHHHHHHHHHHHHHH	40.84	28889911
79	Acetylation	KIDSLENKIDSMTK- HHHHHHHHHHHCCC-	38.22	24489116

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ATIF_YEAST !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ATIF_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ATIF_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SPA2_YEAST	SPA2	physical	11087867
SWC3_YEAST	SWC3	physical	11087867
NNF2_YEAST	NNF2	physical	11087867
DYHC_YEAST	DYN1	physical	11087867
RAD50_YEAST	RAD50	physical	11087867
STF1_YEAST	STF1	physical	16554755
MLC1_YEAST	MLC1	physical	16554755
RUXE_YEAST	SME1	physical	16554755
AP2A_YEAST	APL3	genetic	20093466
RL19A_YEAST	RPL19B	genetic	20093466
RL19B_YEAST	RPL19B	genetic	20093466
SDS24_YEAST	SDS24	genetic	20093466
YCQ6_YEAST	YCR016W	genetic	20093466
SLX5_YEAST	SLX5	genetic	20093466
PUS3_YEAST	DEG1	genetic	20093466
RTF1_YEAST	RTF1	genetic	20093466
GCN1_YEAST	GCN1	genetic	20093466
COX23_YEAST	COX23	genetic	20093466
DHOM_YEAST	HOM6	genetic	20093466
YNM2_YEAST	YNL122C	genetic	20093466
EOS1_YEAST	EOS1	genetic	20093466
RTG1_YEAST	RTG1	genetic	20093466
YAR1_YEAST	YAR1	genetic	20093466
TRM44_YEAST	TRM44	genetic	20093466
THP3_YEAST	THP3	genetic	20093466
ATPA_YEAST	ATP1	physical	6227611
ATP5E_YEAST	ATP15	physical	6227611
ATPD_YEAST	ATP16	physical	6227611
ATPB_YEAST	ATP2	physical	6227611
ATPG_YEAST	ATP3	physical	6227611
MCM1_YEAST	MCM1	genetic	27708008
HSP7F_YEAST	SSE1	genetic	27708008
CDC4_YEAST	CDC4	genetic	27708008
SEC22_YEAST	SEC22	genetic	27708008
TAD3_YEAST	TAD3	genetic	27708008
SEC39_YEAST	SEC39	genetic	27708008
SEC62_YEAST	SEC62	genetic	27708008
RL19A_YEAST	RPL19B	genetic	27708008
RL19B_YEAST	RPL19B	genetic	27708008
CSG2_YEAST	CSG2	genetic	27708008
RTF1_YEAST	RTF1	genetic	27708008
MDM35_YEAST	MDM35	genetic	27708008
EOS1_YEAST	EOS1	genetic	27708008
VPS21_YEAST	VPS21	genetic	27708008
NPT1_YEAST	NPT1	genetic	27708008
RUD3_YEAST	RUD3	genetic	27708008
TRM44_YEAST	TRM44	genetic	27708008
NEW1_YEAST	NEW1	genetic	27708008
KAR3_YEAST	KAR3	genetic	27708008
SIAH1_HUMAN	SIAH1	physical	27107014
CEP63_HUMAN	CEP63	physical	27107014
CEP44_HUMAN	CEP44	physical	27107014

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.