RUXE_YEAST - dbPTM
RUXE_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID RUXE_YEAST
UniProt AC Q12330
Protein Name Small nuclear ribonucleoprotein E
Gene Name SME1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 94
Subcellular Localization Cytoplasm . Nucleus .
Protein Description Involved in pre-mRNA splicing. Binds and is required for the stability of snRNA U1, U2, U4 and U5 which contain a highly conserved structural motif called the Sm binding site. Involved in cap modification..
Protein Sequence MSNKVKTKAMVPPINCIFNFLQQQTPVTIWLFEQIGIRIKGKIVGFDEFMNVVIDEAVEIPVNSADGKEDVEKGTPLGKILLKGDNITLITSAD
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
79UbiquitinationEKGTPLGKILLKGDN
HCCCCCEEEEEECCC
37.5523749301
83UbiquitinationPLGKILLKGDNITLI
CCEEEEEECCCEEEE
61.8523749301

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of RUXE_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of RUXE_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of RUXE_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
SF3B1_YEASTHSH155physical
11805826
RU2A_YEASTLEA1physical
11805826
PRP4_YEASTPRP4physical
11805826
PRP6_YEASTPRP6physical
11805826
PRP9_YEASTPRP9physical
11805826
RSE1_YEASTRSE1physical
11805826
SMD2_YEASTSMD2physical
11805826
SN114_YEASTSNU114physical
11805826
MED20_YEASTSRB2physical
11805826
RUXF_YEASTSMX3physical
9528767
RUXG_YEASTSMX2physical
9528767
LSM3_YEASTLSM3physical
9528767
LSM2_YEASTLSM2physical
9528767
RU17_YEASTSNP1physical
16554755
SMD3_YEASTSMD3physical
16554755
RUXF_YEASTSMX3physical
16554755
RUXF_YEASTSMX3physical
11283351
RUXE_YEASTSME1physical
12618433
RUXF_YEASTSMX3physical
18719252
LSM3_YEASTLSM3physical
18719252
POP6_YEASTPOP6physical
27156450
POP7_YEASTPOP7physical
27156450
EST1_YEASTEST1physical
27156450
TERT_YEASTEST2physical
27156450
MCM1_YEASTMCM1genetic
27708008
MAL32_YEASTMAL32genetic
27708008
TFS2_YEASTDST1genetic
27708008
YP063_YEASTYPR063Cgenetic
27708008
KPYK1_YEASTCDC19genetic
27708008
PRP6_YEASTPRP6genetic
27708008
SP381_YEASTSPP381genetic
27708008
G6PI_YEASTPGI1genetic
27708008
PRP5_YEASTPRP5genetic
27708008
TECR_YEASTTSC13genetic
27708008
PRP9_YEASTPRP9genetic
27708008
PRP11_YEASTPRP11genetic
27708008
LUC7_YEASTLUC7genetic
27708008
KIN28_YEASTKIN28genetic
27708008
RPB1_YEASTRPO21genetic
27708008
SLU7_YEASTSLU7genetic
27708008
ERF3_YEASTSUP35genetic
27708008
SNU56_YEASTSNU56genetic
27708008
SYF1_YEASTSYF1genetic
27708008
PRP3_YEASTPRP3genetic
27708008
MOB2_YEASTMOB2genetic
27708008
SAD1_YEASTSAD1genetic
27708008
CDC20_YEASTCDC20genetic
27708008
PRP43_YEASTPRP43genetic
27708008
GPI10_YEASTGPI10genetic
27708008
PRP18_YEASTPRP18genetic
27708008
SNU71_YEASTSNU71genetic
27708008
PRP38_YEASTPRP38genetic
27708008
PRP31_YEASTPRP31genetic
27708008
TEL2_YEASTTEL2genetic
27708008
NUP57_YEASTNUP57genetic
27708008
MED6_YEASTMED6genetic
27708008
KRE9_YEASTKRE9genetic
27708008
PRP21_YEASTPRP21genetic
27708008
CWC16_YEASTYJU2genetic
27708008
SN114_YEASTSNU114genetic
27708008
YKT6_YEASTYKT6genetic
27708008
SED5_YEASTSED5genetic
27708008
BBP_YEASTMSL5genetic
27708008
CLF1_YEASTCLF1genetic
27708008
SEC22_YEASTSEC22genetic
27708008
RU1C_YEASTYHC1genetic
27708008
AFG2_YEASTAFG2genetic
27708008
RSE1_YEASTRSE1genetic
27708008
CBF3B_YEASTCEP3genetic
27708008
CUS1_YEASTCUS1genetic
27708008
GPI15_YEASTGPI15genetic
27708008
SEC12_YEASTSEC12genetic
27708008
DBP6_YEASTDBP6genetic
27708008
NUF2_YEASTNUF2genetic
27708008
RPA1_YEASTRPA190genetic
27708008
GPI2_YEASTGPI2genetic
27708008
TBF1_YEASTTBF1genetic
27708008
RDS3_YEASTRDS3genetic
27708008
PSB5_YEASTPRE2genetic
27708008
PRP4_YEASTPRP4genetic
27708008
CDC24_YEASTCDC24genetic
27708008
STU1_YEASTSTU1genetic
27708008
AAR2_YEASTAAR2genetic
27708008
SNU23_YEASTSNU23genetic
27708008
NHP2_YEASTNHP2genetic
27708008
PRP28_YEASTPRP28genetic
27708008
COG3_YEASTCOG3genetic
27708008
CWC22_YEASTCWC22genetic
27708008
RPC9_YEASTRPC17genetic
27708008
BOS1_YEASTBOS1genetic
27708008
UTP15_YEASTUTP15genetic
27708008
VTI1_YEASTVTI1genetic
27708008
TF2B_YEASTSUA7genetic
27708008
BUR1_YEASTSGV1genetic
27708008
ATC3_YEASTDRS2genetic
27708008
NUP60_YEASTNUP60genetic
27708008
AVT5_YEASTAVT5genetic
27708008
CSG2_YEASTCSG2genetic
27708008
RU1A_YEASTMUD1genetic
27708008
SWC5_YEASTSWC5genetic
27708008
RS14A_YEASTRPS14Agenetic
27708008
NHP10_YEASTNHP10genetic
27708008
VAM6_YEASTVAM6genetic
27708008
GCS1_YEASTGCS1genetic
27708008
GET1_YEASTGET1genetic
27708008
CGR1_YEASTCGR1genetic
27708008
ATC1_YEASTPMR1genetic
27708008
HUR1_YEASTHUR1genetic
27708008
CWC26_YEASTBUD13genetic
27708008
NPR3_YEASTNPR3genetic
27708008
MED20_YEASTSRB2genetic
27708008
NAM8_YEASTNAM8genetic
27708008
LIN1_YEASTLIN1genetic
27708008
FYV10_YEASTFYV10genetic
27708008
IST3_YEASTIST3genetic
27708008
DAL81_YEASTDAL81genetic
27708008
RS21B_YEASTRPS21Bgenetic
27708008
ISY1_YEASTISY1genetic
27708008
RL14A_YEASTRPL14Agenetic
27708008
MUD2_YEASTMUD2genetic
27708008
RIC1_YEASTRIC1genetic
27708008
RSSA2_YEASTRPS0Bgenetic
27708008
REXO3_YEASTREX3genetic
27708008
PFD6_YEASTYKE2genetic
27708008
ARV1_YEASTARV1genetic
27708008
YPT6_YEASTYPT6genetic
27708008
FKS1_YEASTFKS1genetic
27708008
EAF7_YEASTEAF7genetic
27708008
YNO0_YEASTYNL140Cgenetic
27708008
SWM2_YEASTSWM2genetic
27708008
RMI1_YEASTRMI1genetic
27708008
SUR1_YEASTSUR1genetic
27708008
TGS1_YEASTTGS1genetic
27708008
NCBP2_YEASTCBC2genetic
27708008
RU2A_YEASTLEA1genetic
27708008
VIK1_YEASTVIK1genetic
27708008
BRR1_YEASTBRR1genetic
27708008
YP089_YEASTYPR089Wgenetic
27708008
KAR3_YEASTKAR3genetic
27708008
SMD1_YEASTSMD1genetic
27974620
SMD2_YEASTSMD2genetic
27974620
MUD2_YEASTMUD2genetic
27417296
TGS1_YEASTTGS1genetic
27417296
RU2A_YEASTLEA1genetic
27417296
MSL1_YEASTMSL1genetic
27417296
RU1A_YEASTMUD1genetic
27417296
NAM8_YEASTNAM8genetic
27417296
NCBP2_YEASTCBC2genetic
27417296
RSMB_YEASTSMB1genetic
27417296
SMD3_YEASTSMD3genetic
27417296
RUXF_YEASTSMX3genetic
27417296

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of RUXE_YEAST

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Related Literatures of Post-Translational Modification

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