| UniProt ID | VTI1_YEAST | |
|---|---|---|
| UniProt AC | Q04338 | |
| Protein Name | t-SNARE VTI1 | |
| Gene Name | VTI1 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 217 | |
| Subcellular Localization |
Prevacuolar compartment membrane Single-pass type IV membrane protein. Golgi apparatus membrane Single-pass type IV membrane protein. A small portion is localized in the Golgi apparatus, the majority is localized in the PVC. |
|
| Protein Description | t-SNARE found in various SNARE complexes involved in multiple transport pathways. The composition of the t-SNARE complexes is specific for a limited number of v-SNAREs and therefore allows only the vesicles carrying the matching v-SNARE to fuse.. | |
| Protein Sequence | MSSLLISYESDFKTTLEQAKASLAEAPSQPLSQRNTTLKHVEQQQDELFDLLDQMDVEVNNSIGDASERATYKAKLREWKKTIQSDIKRPLQSLVDSGDRDRLFGDLNASNIDDDQRQQLLSNHAILQKSGDRLKDASRIANETEGIGSQIMMDLRSQRETLENARQTLFQADSYVDKSIKTLKTMTRRLVANKFISYAIIAVLILLILLVLFSKFK | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 2 | Acetylation | ------MSSLLISYE ------CCCCEECCC | 29.68 | - | |
| 2 | Phosphorylation | ------MSSLLISYE ------CCCCEECCC | 29.68 | 30377154 | |
| 3 | Phosphorylation | -----MSSLLISYES -----CCCCEECCCC | 26.37 | 30377154 | |
| 20 | Ubiquitination | KTTLEQAKASLAEAP HHHHHHHHHHHHHCC | 37.90 | 23749301 | |
| 22 | Phosphorylation | TLEQAKASLAEAPSQ HHHHHHHHHHHCCCC | 27.66 | 19823750 | |
| 28 | Phosphorylation | ASLAEAPSQPLSQRN HHHHHCCCCCHHHCC | 52.02 | 19823750 | |
| 32 | Phosphorylation | EAPSQPLSQRNTTLK HCCCCCHHHCCCHHH | 33.50 | 19823750 | |
| 36 | Phosphorylation | QPLSQRNTTLKHVEQ CCHHHCCCHHHHHHH | 35.38 | 19823750 | |
| 37 | Phosphorylation | PLSQRNTTLKHVEQQ CHHHCCCHHHHHHHH | 37.04 | 19823750 | |
| 85 | Phosphorylation | EWKKTIQSDIKRPLQ HHHHHHHHHCHHHHH | 37.14 | 30377154 | |
| 97 | Phosphorylation | PLQSLVDSGDRDRLF HHHHHHHCCCHHHHH | 34.80 | 24961812 | |
| 110 | Phosphorylation | LFGDLNASNIDDDQR HHCCCCCCCCCHHHH | 32.99 | 28889911 | |
| 129 | Ubiquitination | SNHAILQKSGDRLKD HCCHHHHHHCCHHHH | 53.62 | 23749301 | |
| 149 | Phosphorylation | NETEGIGSQIMMDLR HHCCCHHHHHHHHHH | 18.02 | 9446565 | |
| 178 | Ubiquitination | QADSYVDKSIKTLKT HHHHHHHHHHHHHHH | 44.00 | 23749301 | |
| 181 | Ubiquitination | SYVDKSIKTLKTMTR HHHHHHHHHHHHHHH | 55.70 | 22817900 | |
| 184 | Ubiquitination | DKSIKTLKTMTRRLV HHHHHHHHHHHHHHH | 41.29 | 23749301 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of VTI1_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of VTI1_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of VTI1_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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| Phosphorylation | |
| Reference | PubMed |
| "A multidimensional chromatography technology for in-depthphosphoproteome analysis."; Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.; Mol. Cell. Proteomics 7:1389-1396(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-110 AND SER-149, ANDMASS SPECTROMETRY. | |
