| UniProt ID | GGPPS_YEAST | |
|---|---|---|
| UniProt AC | Q12051 | |
| Protein Name | Geranylgeranyl pyrophosphate synthase | |
| Gene Name | BTS1 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 335 | |
| Subcellular Localization | Cytoplasm. | |
| Protein Description | Catalyzes the trans-addition of the 3 molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate. Required for the membrane attachment of YPT1 and SEC4. May be involved in vesicle trafficking and protein sorting.. | |
| Protein Sequence | MEAKIDELINNDPVWSSQNESLISKPYNHILLKPGKNFRLNLIVQINRVMNLPKDQLAIVSQIVELLHNSSLLIDDIEDNAPLRRGQTTSHLIFGVPSTINTANYMYFRAMQLVSQLTTKEPLYHNLITIFNEELINLHRGQGLDIYWRDFLPEIIPTQEMYLNMVMNKTGGLFRLTLRLMEALSPSSHHGHSLVPFINLLGIIYQIRDDYLNLKDFQMSSEKGFAEDITEGKLSFPIVHALNFTKTKGQTEQHNEILRILLLRTSDKDIKLKLIQILEFDTNSLAYTKNFINQLVNMIKNDNENKYLPDLASHSDTATNLHDELLYIIDHLSEL | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 16 | Phosphorylation | INNDPVWSSQNESLI HHCCCCCCCCCCHHH | 23.45 | 19823750 | |
| 17 | Phosphorylation | NNDPVWSSQNESLIS HCCCCCCCCCCHHHC | 22.70 | 19823750 | |
| 21 | Phosphorylation | VWSSQNESLISKPYN CCCCCCCHHHCCCCC | 38.25 | 19823750 | |
| 24 | Phosphorylation | SQNESLISKPYNHIL CCCCHHHCCCCCEEE | 32.63 | 19823750 | |
| 27 | Phosphorylation | ESLISKPYNHILLKP CHHHCCCCCEEEECC | 24.10 | 19823750 | |
| 246 | Acetylation | VHALNFTKTKGQTEQ EEEHHCCCCCCCHHH | 44.07 | 24489116 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of GGPPS_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of GGPPS_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of GGPPS_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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