IPK1_YEAST - dbPTM
IPK1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID IPK1_YEAST
UniProt AC Q06667
Protein Name Inositol-pentakisphosphate 2-kinase
Gene Name IPK1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 281
Subcellular Localization Nucleus .
Protein Description Has kinase activity and phosphorylates inositol-1,3,4,5,6-pentakisphosphate (Ins(1,3,4,5,6)P5) to produce 1,2,3,4,5,6-hexakisphosphate (InsP6), also known as phytate..
Protein Sequence MQVIGRGGANILIDYGDPTWLWRCCIRWPDLLSSNNSYTIKNISYIKDYVEPLLHGLLCPMYLIDVDIEAIRPILSDFILNLDDKVVKVIKIKNLTNNTSNLILNNHFLKSYCSQNLQTVILELKPKWLYYDTDYCRNCTHNAFKGRGTKYCYNQLLMNPAHLELIFGECNIFPVKFKDAMHEYLRNDNNIFKILYDLQKKLTKNTTPISDIKSINDVNDEHLLLMTLRDVTCFIEWNSAENALHVNIIDVDLKPKEKWTHWTKTYSQLTSSQKIYHTSNK
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
111PhosphorylationLNNHFLKSYCSQNLQ
ECHHHHHHHHCCCCC
33.2526447709
112PhosphorylationNNHFLKSYCSQNLQT
CHHHHHHHHCCCCCE
8.4326447709
114PhosphorylationHFLKSYCSQNLQTVI
HHHHHHHCCCCCEEE
17.5526447709
196PhosphorylationNNIFKILYDLQKKLT
CCHHHHHHHHHHHHC
20.3427017623
263PhosphorylationKEKWTHWTKTYSQLT
HHHCCCHHHCHHHHH
13.1021440633
265PhosphorylationKWTHWTKTYSQLTSS
HCCCHHHCHHHHHCC
22.4921440633

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of IPK1_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of IPK1_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of IPK1_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
RS28B_YEASTRPS28Bphysical
10688190
STE24_YEASTSTE24physical
10688190
CWC24_YEASTCWC24physical
10688190
BUD21_YEASTBUD21physical
10688190
IPMK_YEASTARG82genetic
14618376
GLE1_YEASTGLE1genetic
15459192
DBP5_YEASTDBP5genetic
15459192
NUP42_YEASTNUP42genetic
15459192
NU116_YEASTNUP116genetic
15459192
NU159_YEASTNUP159genetic
15459192
GLE2_YEASTGLE2genetic
15459192
STE2_YEASTSTE2genetic
15459192
DBP5_YEASTDBP5genetic
16783363
DHH1_YEASTDHH1genetic
16783363
CYC8_YEASTCYC8genetic
19269370
TPS1_YEASTTPS1genetic
19269370
MRC1_YEASTMRC1genetic
19269370
KCS1_YEASTKCS1genetic
19269370
SEM1_YEASTSEM1genetic
19269370
LSM6_YEASTLSM6genetic
19269370
NPY1_YEASTNPY1genetic
19269370
MED31_YEASTSOH1genetic
19269370
CWC26_YEASTBUD13genetic
19269370
HXKB_YEASTHXK2genetic
19269370
PPX1_YEASTPPX1genetic
19269370
IST3_YEASTIST3genetic
19269370
CUL8_YEASTRTT101genetic
19269370
LSM1_YEASTLSM1genetic
19269370
RPA34_YEASTRPA34genetic
19269370
ADK_YEASTADO1genetic
19269370
MUD2_YEASTMUD2genetic
19269370
VIP1_YEASTVIP1genetic
19269370
CSM3_YEASTCSM3genetic
19269370
PFD4_YEASTGIM3genetic
19269370
PHO80_YEASTPHO80genetic
19269370
H2AZ_YEASTHTZ1genetic
19269370
SKS1_YEASTSKS1genetic
19269370
PLC1_YEASTPLC1genetic
19269370
ERF1_YEASTSUP45genetic
18724935
DBP5_YEASTDBP5genetic
19805289
LTE1_YEASTLTE1genetic
20093466
KPR4_YEASTPRS4genetic
20093466
HAP3_YEASTHAP3genetic
20093466
FMT_YEASTFMT1genetic
20093466
C1TM_YEASTMIS1genetic
20093466
ARL1_YEASTARL1genetic
20093466
SEC66_YEASTSEC66genetic
20093466
MRC1_YEASTMRC1genetic
20093466
HCM1_YEASTHCM1genetic
20093466
PAT1_YEASTPAT1genetic
20093466
PHO2_YEASTPHO2genetic
20093466
QRI7_YEASTQRI7genetic
20093466
MTU1_YEASTSLM3genetic
20093466
RM01_YEASTMRPL1genetic
20093466
RSM28_YEASTRSM28genetic
20093466
CAJ1_YEASTCAJ1genetic
20093466
VTC1_YEASTVTC1genetic
20093466
HAC1_YEASTHAC1genetic
20093466
QCR6_YEASTQCR6genetic
20093466
MTO1_YEASTMTO1genetic
20093466
YGY5_YEASTYGL235Wgenetic
20093466
CWC26_YEASTBUD13genetic
20093466
MED5_YEASTNUT1genetic
20093466
RT13_YEASTMRP13genetic
20093466
ASK10_YEASTASK10genetic
20093466
QCR9_YEASTQCR9genetic
20093466
UBR1_YEASTUBR1genetic
20093466
FSH1_YEASTFSH1genetic
20093466
PTH_YEASTPTH1genetic
20093466
IMPX_YEASTIMP2genetic
20093466
PTPA1_YEASTRRD1genetic
20093466
COPE_YEASTSEC28genetic
20093466
APQ12_YEASTAPQ12genetic
20093466
IST3_YEASTIST3genetic
20093466
RPA34_YEASTRPA34genetic
20093466
LSM1_YEASTLSM1genetic
20093466
DPOD3_YEASTPOL32genetic
20093466
OPLA_YEASTOXP1genetic
20093466
LST4_YEASTLST4genetic
20093466
FEN1_YEASTRAD27genetic
20093466
LHS1_YEASTLHS1genetic
20093466
ELM1_YEASTELM1genetic
20093466
YKR18_YEASTYKR018Cgenetic
20093466
BAS1_YEASTBAS1genetic
20093466
RSC2_YEASTRSC2genetic
20093466
VAC14_YEASTVAC14genetic
20093466
COX8_YEASTCOX8genetic
20093466
MSC1_YEASTMSC1genetic
20093466
GTR1_YEASTGTR1genetic
20093466
PPZ1_YEASTPPZ1genetic
20093466
MSS1_YEASTMSS1genetic
20093466
CSM3_YEASTCSM3genetic
20093466
CIK1_YEASTCIK1genetic
20093466
EAF7_YEASTEAF7genetic
20093466
COX5A_YEASTCOX5Agenetic
20093466
MED9_YEASTCSE2genetic
20093466
ATP23_YEASTATP23genetic
20093466
IRA2_YEASTIRA2genetic
20093466
KPR5_YEASTPRS5genetic
20093466
MDM38_YEASTMDM38genetic
20093466
MDM12_YEASTMDM12genetic
20093466
COQ10_YEASTCOQ10genetic
20093466
HST3_YEASTHST3genetic
20093466
PNT1_YEASTPNT1genetic
20093466
MRS2_YEASTMRS2genetic
20093466
HAP5_YEASTHAP5genetic
20093466
CTI6_YEASTCTI6genetic
20093466
LPE10_YEASTMFM1genetic
20093466
RLF2_YEASTRLF2genetic
20093466
AP1G1_YEASTAPL4genetic
20093466
TIP41_YEASTTIP41genetic
20093466
JID1_YEASTJID1genetic
20093466
AXL1_YEASTAXL1genetic
20093466
KAR3_YEASTKAR3genetic
20093466
GPT1_YEASTSCT1genetic
21623372
KCS1_YEASTKCS1genetic
21623372
COX10_YEASTCOX10genetic
21623372
ARGJ_YEASTARG7genetic
21623372
KPR5_YEASTPRS5genetic
21623372
FUMH_YEASTFUM1genetic
21623372
KPR4_YEASTPRS4genetic
21623372
PHO87_YEASTPHO87genetic
21623372
UGPA2_YEASTYHL012Wgenetic
21623372
ADK_YEASTADO1genetic
21623372
ATP5E_YEASTATP15genetic
21623372
APC11_YEASTAPC11genetic
27708008
DPOD_YEASTPOL3genetic
27708008
GPI10_YEASTGPI10genetic
27708008
BET3_YEASTBET3genetic
27708008
RPC6_YEASTRPC34genetic
27708008
CLP1_YEASTCLP1genetic
27708008
AAKG_YEASTSNF4genetic
27708008
CHO2_YEASTCHO2genetic
27708008
VPS53_YEASTVPS53genetic
27708008
RFA1_YEASTRFA1genetic
27708008
CDC15_YEASTCDC15genetic
27708008
STU1_YEASTSTU1genetic
27708008
DPOA2_YEASTPOL12genetic
27708008
CALM_YEASTCMD1genetic
27708008
CKS1_YEASTCKS1genetic
27708008
CDK1_YEASTCDC28genetic
27708008
MPS1_YEASTMPS1genetic
27708008
PRP9_YEASTPRP9genetic
27708008
RPN6_YEASTRPN6genetic
27708008
NSE4_YEASTNSE4genetic
27708008
CDC48_YEASTCDC48genetic
27708008
GLE1_YEASTGLE1genetic
27708008
DAD1_YEASTDAD1genetic
27708008
MOB2_YEASTMOB2genetic
27708008
ACT_YEASTACT1genetic
27708008
CDC14_YEASTCDC14genetic
27708008
RPN12_YEASTRPN12genetic
27708008
SLD3_YEASTSLD3genetic
27708008
MCE1_YEASTCEG1genetic
27708008
BRR6_YEASTBRR6genetic
27708008
PRP18_YEASTPRP18genetic
27708008
CWC22_YEASTCWC22genetic
27708008
MPPA_YEASTMAS2genetic
27708008
ORC6_YEASTORC6genetic
27708008
UTP9_YEASTUTP9genetic
27708008
MOB1_YEASTMOB1genetic
27708008
PRI1_YEASTPRI1genetic
27708008
DSN1_YEASTDSN1genetic
27708008
STS1_YEASTSTS1genetic
27708008
PSF2_YEASTPSF2genetic
27708008
DPOD2_YEASTPOL31genetic
27708008
NUP85_YEASTNUP85genetic
27708008
CDT1_YEASTTAH11genetic
27708008
KTHY_YEASTCDC8genetic
27708008
CDC11_YEASTCDC11genetic
27708008
TOR2_YEASTTOR2genetic
27708008
ORC3_YEASTORC3genetic
27708008
PRP19_YEASTPRP19genetic
27708008
COFI_YEASTCOF1genetic
27708008
MED14_YEASTRGR1genetic
27708008
CLF1_YEASTCLF1genetic
27708008
SEC13_YEASTSEC13genetic
27708008
MCM5_YEASTMCM5genetic
27708008
TAD3_YEASTTAD3genetic
27708008
IMB1_YEASTKAP95genetic
27708008
NBP1_YEASTNBP1genetic
27708008
ORC1_YEASTORC1genetic
27708008
TAF13_YEASTTAF13genetic
27708008
MCM1_YEASTMCM1genetic
27708008
PDS5_YEASTPDS5genetic
27708008
CBF3B_YEASTCEP3genetic
27708008
NOP2_YEASTNOP2genetic
27708008
DPOA_YEASTPOL1genetic
27708008
DCP2_YEASTDCP2genetic
27708008
TYSY_YEASTCDC21genetic
27708008
TOA1_YEASTTOA1genetic
27708008
DYR_YEASTDFR1genetic
27708008
SYLC_YEASTCDC60genetic
27708008
SYH_YEASTHTS1genetic
27708008
ORC4_YEASTORC4genetic
27708008
LTE1_YEASTLTE1genetic
27708008
FMT_YEASTFMT1genetic
27708008
PIN4_YEASTPIN4genetic
27708008
KPR4_YEASTPRS4genetic
27708008
C1TM_YEASTMIS1genetic
27708008
NPL4_YEASTNPL4genetic
27708008
NTC20_YEASTNTC20genetic
27708008
MRC1_YEASTMRC1genetic
27708008
PAT1_YEASTPAT1genetic
27708008
MTU1_YEASTSLM3genetic
27708008
QRI7_YEASTQRI7genetic
27708008
PHO2_YEASTPHO2genetic
27708008
CAJ1_YEASTCAJ1genetic
27708008
UBP3_YEASTUBP3genetic
27708008
QCR6_YEASTQCR6genetic
27708008
CWC26_YEASTBUD13genetic
27708008
YGY5_YEASTYGL235Wgenetic
27708008
MTO1_YEASTMTO1genetic
27708008
RTG2_YEASTRTG2genetic
27708008
YG1D_YEASTYGR021Wgenetic
27708008
RT13_YEASTMRP13genetic
27708008
QCR9_YEASTQCR9genetic
27708008
FSH1_YEASTFSH1genetic
27708008
PTH_YEASTPTH1genetic
27708008
PTPA1_YEASTRRD1genetic
27708008
IMPX_YEASTIMP2genetic
27708008
IST3_YEASTIST3genetic
27708008
LSM1_YEASTLSM1genetic
27708008
MRX5_YEASTYJL147Cgenetic
27708008
RPA34_YEASTRPA34genetic
27708008
DPOD3_YEASTPOL32genetic
27708008
IME1_YEASTIME1genetic
27708008
LHS1_YEASTLHS1genetic
27708008
RM49_YEASTMRP49genetic
27708008
LST4_YEASTLST4genetic
27708008
MEH1_YEASTMEH1genetic
27708008
BAS1_YEASTBAS1genetic
27708008
COX8_YEASTCOX8genetic
27708008
PPZ1_YEASTPPZ1genetic
27708008
GTR1_YEASTGTR1genetic
27708008
MSS1_YEASTMSS1genetic
27708008
CSM3_YEASTCSM3genetic
27708008
MAS5_YEASTYDJ1genetic
27708008
TOM7_YEASTTOM7genetic
27708008
EAF7_YEASTEAF7genetic
27708008
ATP23_YEASTATP23genetic
27708008
MDM38_YEASTMDM38genetic
27708008
KPR5_YEASTPRS5genetic
27708008
HST3_YEASTHST3genetic
27708008
CYC2_YEASTCYC2genetic
27708008
HIR2_YEASTHIR2genetic
27708008
PNT1_YEASTPNT1genetic
27708008
MRS2_YEASTMRS2genetic
27708008
LPE10_YEASTMFM1genetic
27708008
MGR2_YEASTMGR2genetic
27708008
AP1G1_YEASTAPL4genetic
27708008
AXL1_YEASTAXL1genetic
27708008
MSS18_YEASTMSS18genetic
27708008
KAR3_YEASTKAR3genetic
27708008
QCR2_YEASTQCR2genetic
27708008
FXR2_HUMANFXR2physical
27107014

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of IPK1_YEAST

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Related Literatures of Post-Translational Modification

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