| UniProt ID | RPC6_YEAST | |
|---|---|---|
| UniProt AC | P32910 | |
| Protein Name | DNA-directed RNA polymerase III subunit RPC6 | |
| Gene Name | RPC34 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 317 | |
| Subcellular Localization | Nucleus. | |
| Protein Description | DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Involved in recruitment of Pol III to the preinitiation complex. Involved in the configuration of an initiation-competent form of RNA polymerase.. | |
| Protein Sequence | MSGMIENGLQLSDNAKTLHSQMMSKGIGALFTQQELQKQMGIGSLTDLMSIVQELLDKNLIKLVKQNDELKFQGVLESEAQKKATMSAEEALVYSYIEASGREGIWSKTIKARTNLHQHVVLKCLKSLESQRYVKSVKSVKFPTRKIYMLYSLQPSVDITGGPWFTDGELDIEFINSLLTIVWRFISENTFPNGFKNFENGPKKNVFYAPNVKNYSTTQEILEFITAAQVANVELTPSNIRSLCEVLVYDDKLEKVTHDCYRVTLESILQMNQGEGEPEAGNKALEDEEEFSIFNYFKMFPASKHDKEVVYFDEWTI | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 2 | Phosphorylation | ------MSGMIENGL ------CCCCCCCCE | 36.75 | 29136822 | |
| 12 | Phosphorylation | IENGLQLSDNAKTLH CCCCEECCCCHHHHH | 18.83 | 29136822 | |
| 17 | Phosphorylation | QLSDNAKTLHSQMMS ECCCCHHHHHHHHHH | 27.56 | 28132839 | |
| 20 | Phosphorylation | DNAKTLHSQMMSKGI CCHHHHHHHHHHHCH | 23.92 | 28132839 | |
| 32 | Phosphorylation | KGIGALFTQQELQKQ HCHHHHHCHHHHHHH | 30.14 | 28132839 | |
| 87 | Phosphorylation | AQKKATMSAEEALVY HHHHHCCCHHHHHHH | 28.33 | 28889911 | |
| 94 | Phosphorylation | SAEEALVYSYIEASG CHHHHHHHHHHHHCC | 9.15 | 28889911 | |
| 95 | Phosphorylation | AEEALVYSYIEASGR HHHHHHHHHHHHCCC | 16.50 | 28889911 | |
| 100 | Phosphorylation | VYSYIEASGREGIWS HHHHHHHCCCCCCCC | 26.12 | 28889911 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of RPC6_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of RPC6_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of RPC6_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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