| UniProt ID | GCR2_YEAST | |
|---|---|---|
| UniProt AC | Q01722 | |
| Protein Name | Glycolytic genes transcriptional activator GCR2 | |
| Gene Name | GCR2 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 534 | |
| Subcellular Localization | Nucleus . | |
| Protein Description | Transcriptional activator required for the expression of glycolytic genes. Enhances the CT box-dependent transcriptional activation of a RAP1-GCR1 complex. Required for GCR1 phosphorylation.. | |
| Protein Sequence | MHHQTKLDVFIIRAYNLLSNESVISGASLQSVTNSPQTTTNTPSGMVNGAVGTGIANPTGLMGSDSTPNIDEIITSTGSNALTKTNSDSANGTPNGNSSSTSAISNASNPATTGNNASSSATSNGIYTQAQYSQLFAKISKLYNATLSSGSIDDRSTSPKSAIELYQRFQQMIKELELSFDASPYAKYFRRLDGRLWQIKTDSELENDELWRLVSMSIFTVFDPQTGQILTQGRRKGNSLNTSTKGSPSDLQGINNGNNNGNNGNIGNGSNIKNYGNKNMPNNRTKKRGTRVAKNAKNGKNNKNSNKERNGITDTSAFSNTTISNPGTNMLFDPSLSQQLQKRLQTLSQDVNSRSLTGYYTQPTSPGSGGFEFGLSHADLNPNASSNTMGYNTMSNNGSHSWKRRSLGSLDVNTLDDEAVEELLQLTNTSKRQRPMTTAAEGALINDGPDTNLNANNTQMKVDLNPSNSMGPIDTEAVIRPLKEAYDAIISEKGQRIVQLERELELQRQETQWLRKMLIEDMGCVRSMLRDLQR | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 143 | Phosphorylation | FAKISKLYNATLSSG HHHHHHHHHCCCCCC | 13.39 | 27017623 | |
| 146 | Phosphorylation | ISKLYNATLSSGSID HHHHHHCCCCCCCCC | 24.43 | 27017623 | |
| 149 | Phosphorylation | LYNATLSSGSIDDRS HHHCCCCCCCCCCCC | 39.41 | 30377154 | |
| 151 | Phosphorylation | NATLSSGSIDDRSTS HCCCCCCCCCCCCCC | 25.45 | 21440633 | |
| 239 | Phosphorylation | QGRRKGNSLNTSTKG CCCCCCCCCCCCCCC | 31.50 | 20377248 | |
| 242 | Phosphorylation | RKGNSLNTSTKGSPS CCCCCCCCCCCCCHH | 42.96 | 21440633 | |
| 243 | Phosphorylation | KGNSLNTSTKGSPSD CCCCCCCCCCCCHHH | 27.35 | 20377248 | |
| 244 | Phosphorylation | GNSLNTSTKGSPSDL CCCCCCCCCCCHHHH | 37.07 | 20377248 | |
| 247 | Phosphorylation | LNTSTKGSPSDLQGI CCCCCCCCHHHHCCC | 23.84 | 22369663 | |
| 249 | Phosphorylation | TSTKGSPSDLQGINN CCCCCCHHHHCCCCC | 53.29 | 22369663 | |
| 270 | Phosphorylation | NGNIGNGSNIKNYGN CCCCCCCCCCCCCCC | 39.11 | 19823750 | |
| 278 | Acetylation | NIKNYGNKNMPNNRT CCCCCCCCCCCCCCC | 50.70 | 22865919 | |
| 348 | Phosphorylation | QKRLQTLSQDVNSRS HHHHHHHCHHHHHCC | 27.93 | 28889911 | |
| 406 | Phosphorylation | SHSWKRRSLGSLDVN CCCCEECCCCCCCCC | 40.91 | 22369663 | |
| 409 | Phosphorylation | WKRRSLGSLDVNTLD CEECCCCCCCCCCCC | 27.04 | 20377248 | |
| 414 | Phosphorylation | LGSLDVNTLDDEAVE CCCCCCCCCCHHHHH | 31.26 | 22369663 | |
| 427 | Phosphorylation | VEELLQLTNTSKRQR HHHHHHHHCCCCCCC | 24.40 | 22369663 | |
| 429 | Phosphorylation | ELLQLTNTSKRQRPM HHHHHHCCCCCCCCC | 30.32 | 22369663 | |
| 430 | Phosphorylation | LLQLTNTSKRQRPMT HHHHHCCCCCCCCCC | 28.10 | 22369663 | |
| 467 | Phosphorylation | MKVDLNPSNSMGPID EEEECCCCCCCCCCC | 40.23 | 30377154 | |
| 469 | Phosphorylation | VDLNPSNSMGPIDTE EECCCCCCCCCCCHH | 29.47 | 30377154 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of GCR2_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of GCR2_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of GCR2_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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| Phosphorylation | |
| Reference | PubMed |
| "A multidimensional chromatography technology for in-depthphosphoproteome analysis."; Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.; Mol. Cell. Proteomics 7:1389-1396(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-151 AND SER-348, ANDMASS SPECTROMETRY. | |
