| UniProt ID | VPS9_YEAST | |
|---|---|---|
| UniProt AC | P54787 | |
| Protein Name | Vacuolar protein sorting-associated protein 9 | |
| Gene Name | VPS9 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 451 | |
| Subcellular Localization | Cytoplasm. | |
| Protein Description | Required for vacuolar protein sorting; may be required for the consumption of transport vesicles containing vacuolar protein precursors. May bind a Rab GTPase such as VPS21.. | |
| Protein Sequence | MTDDEKREILKEFDPFSQLEQANGNPDKDVKFKKDDPNRAAAEETNRDISAQDKGDEEPFYDFQIFIKQLQTPGADPLVKYTKSFLRNFLAQRLLWTVSEEIKLISDFKTFIYDKFTLYEPFRSLDNSKMRNAKEGMEKLIMGKLYSRCFSPSLYEILQKPLDDEHMKDLTNDDTLLEKIRHYRFISPIMLDIPDTMPNARLNKFVHLASKELGKINRFKSPRDKMVCVLNASKVIFGLLKHTKLEQNGADSFIPVLIYCILKGQVRYLVSNVNYIERFRSPDFIRGEEEYYLSSLQAALNFIMNLTERSLTIEDHEDFEEAYQRNFKQLAEEKEEEEKKKQLEIPDELQPNGTLLKPLDEVTNIVISKFNELFSPIGEPTQEEALKSEQSNKEEDVSSLIKKIEENERKDTLNTLQNMFPDMDPSLIEDVCIAKKSRIGPCVDALLSLSE | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 11 | Ubiquitination | DEKREILKEFDPFSQ HHHHHHHHHCCHHHH | 63.09 | 24961812 | |
| 28 | Acetylation | QANGNPDKDVKFKKD HHCCCCCCCCCCCCC | 66.72 | 24489116 | |
| 28 | Ubiquitination | QANGNPDKDVKFKKD HHCCCCCCCCCCCCC | 66.72 | 23749301 | |
| 68 | Ubiquitination | YDFQIFIKQLQTPGA CCHHHHHHHHCCCCC | 33.92 | 24961812 | |
| 139 | Acetylation | NAKEGMEKLIMGKLY CHHHHHHHHHHHHHH | 34.13 | 24489116 | |
| 211 | Acetylation | KFVHLASKELGKINR HHHHHHHHHHCCCCC | 51.88 | 24489116 | |
| 244 | Ubiquitination | FGLLKHTKLEQNGAD HHHHHHCCHHHCCCC | 50.15 | 23749301 | |
| 375 | Phosphorylation | SKFNELFSPIGEPTQ HHHHHHCCCCCCCCH | 28.38 | 19823750 | |
| 381 | Phosphorylation | FSPIGEPTQEEALKS CCCCCCCCHHHHHHH | 44.29 | 28889911 | |
| 387 | Ubiquitination | PTQEEALKSEQSNKE CCHHHHHHHHHCCCH | 60.02 | 23749301 | |
| 393 | Ubiquitination | LKSEQSNKEEDVSSL HHHHHCCCHHHHHHH | 68.66 | 23749301 | |
| 398 | Phosphorylation | SNKEEDVSSLIKKIE CCCHHHHHHHHHHHH | 31.58 | 22369663 | |
| 399 | Phosphorylation | NKEEDVSSLIKKIEE CCHHHHHHHHHHHHH | 33.68 | 22369663 | |
| 402 | Ubiquitination | EDVSSLIKKIEENER HHHHHHHHHHHHHHH | 53.65 | 23749301 | |
| 403 | Ubiquitination | DVSSLIKKIEENERK HHHHHHHHHHHHHHH | 48.64 | 23749301 | |
| 437 | Phosphorylation | DVCIAKKSRIGPCVD HHHHHCCCCCCHHHH | 28.55 | 21126336 | |
| 448 | Phosphorylation | PCVDALLSLSE---- HHHHHHHHCCC---- | 30.60 | 21126336 |
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of VPS9_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of VPS9_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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| Phosphorylation | |
| Reference | PubMed |
| "A multidimensional chromatography technology for in-depthphosphoproteome analysis."; Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.; Mol. Cell. Proteomics 7:1389-1396(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-375, AND MASSSPECTROMETRY. | |
