YPS7_YEAST - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: YPS7_YEAST
• UniProt AC: Q06325
• Protein Name: Aspartic proteinase yapsin-7
• Gene Name: YPS7
• Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
• Sequence Length: 596
• Subcellular Localization: Cytoplasm . Endoplasmic reticulum membrane ; Single-pass type I membrane protein .
• Protein Sequence: MTCLILWYLWLISTFQLEFATASTANTTTTAKSGTSSSTEEPFPVLAVGKDGRGNYYVNSTFGTPGQRQRLLVDIIQPYINLVSGTSESHNEYSGVYHKHPSYLMNDSTSSVPVSPGQIYEISFIDGRAVNCTLVTDDMNFTNVSSENSSTALITDLMVTRDNVQFNSGSLSISNVSFFDIQSSNFKTSGLLGLSGKVTNPGNAIDSSQYTEQSYFLSLLKDADIIESSSYSLWLAGDTSTYKTYRDPISNCGKLLLGGVDPSLFTGTLGKFDLIPYVDPVSNAVSVGYPIVPLGPIYIVSNSGQSLNMTSKDFLSPALLDSTSSVSYLPTSTIIQIAVQIAATYVESLDRWLVQCSIADMGVSLGFRLRELTIEIPLRDLLSSTYDTSTNSSMFFSSGQEACFLTLYANTNTGVNILGEAFIKNIYMAMDLEDNTIAIAQAKKVEDDAVTEETNETTASTIIKKIKSGYIPYAKVMNSSNTRNLTLYPSYRSGYMFTVPGQLTAAYSNGVITGAGRSFYDTSRASTSARPSSTQFDSFSVSASEEWSNSTNRTSSASGAGVRLSSPYTFNKDPAGHVTRIASLLLLSIFSILIVL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
26	N-linked_Glycosylation	FATASTANTTTTAKS HHHCCCCCCEEECCC	37.74	-
59	N-linked_Glycosylation	GRGNYYVNSTFGTPG CCCCEEECCCCCCCC	21.15	-
60	Phosphorylation	RGNYYVNSTFGTPGQ CCCEEECCCCCCCCC	18.31	27017623
64	Phosphorylation	YVNSTFGTPGQRQRL EECCCCCCCCCHHHH	21.76	27017623
106	N-linked_Glycosylation	KHPSYLMNDSTSSVP CCHHHHCCCCCCCCC	37.17	-
131	N-linked_Glycosylation	FIDGRAVNCTLVTDD EECCEEEEEEEEECC	16.45	-
140	N-linked_Glycosylation	TLVTDDMNFTNVSSE EEEECCCCCCCCCCC	47.81	-
143	N-linked_Glycosylation	TDDMNFTNVSSENSS ECCCCCCCCCCCCCC	27.77	-
148	N-linked_Glycosylation	FTNVSSENSSTALIT CCCCCCCCCCCEEEE	43.11	-
175	N-linked_Glycosylation	SGSLSISNVSFFDIQ CCEEEEEEEEEEEEC	31.61	-
308	N-linked_Glycosylation	SNSGQSLNMTSKDFL CCCCCCCCCCCCCCC	36.61	-
391	N-linked_Glycosylation	STYDTSTNSSMFFSS CCCCCCCCCCCCCCC	31.67	-
455	N-linked_Glycosylation	DAVTEETNETTASTI CCCCCCCCCCCHHHH	48.15	-
478	N-linked_Glycosylation	IPYAKVMNSSNTRNL CCCEEEECCCCCCCE	45.32	-
484	N-linked_Glycosylation	MNSSNTRNLTLYPSY ECCCCCCCEEECCCC	35.03	-
549	N-linked_Glycosylation	SASEEWSNSTNRTSS ECCHHHCCCCCCCCC	54.66	-
552	N-linked_Glycosylation	EEWSNSTNRTSSASG HHHCCCCCCCCCCCC	45.08	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of YPS7_YEAST !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of YPS7_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of YPS7_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
MNN1_YEAST	MNN1	genetic	16269340
YJR1_YEAST	YJL171C	genetic	16269340
PMT6_YEAST	PMT6	genetic	16269340
PMT7_YEAST	PMT7	genetic	16269340
PGA3_YEAST	PGA3	genetic	16269340
ATC1_YEAST	PMR1	genetic	16269340
RGP1_YEAST	RGP1	genetic	16269340
COPE_YEAST	SEC28	genetic	16269340
BCK1_YEAST	BCK1	genetic	23891562
CWH43_YEAST	CWH43	genetic	23891562
VPS1_YEAST	VPS1	genetic	23891562
CCW12_YEAST	CCW12	genetic	23891562
ERG3_YEAST	ERG3	genetic	23891562
TBCA_YEAST	RBL2	genetic	23891562
ELO3_YEAST	ELO3	genetic	23891562
CSG2_YEAST	CSG2	genetic	23891562
MCFS2_YEAST	EHT1	genetic	27708008
SLT2_YEAST	SLT2	genetic	27708008
BCK1_YEAST	BCK1	genetic	27708008
YJR1_YEAST	YJL171C	genetic	27708008
PALI_YEAST	RIM9	genetic	27708008
YHM2_YEAST	YHM2	genetic	27708008
SSK2_YEAST	SSK2	genetic	27708008
PALA_YEAST	RIM20	genetic	27708008

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.