CWH43_YEAST - dbPTM
CWH43_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID CWH43_YEAST
UniProt AC P25618
Protein Name Protein CWH43
Gene Name CWH43
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 953
Subcellular Localization Cell membrane
Multi-pass membrane protein. Endoplasmic reticulum membrane
Multi-pass membrane protein. Concentrates to the bud tip of small budded cells and to the neck of dividing cells.
Protein Description Involved in the maintenance of cell wall integrity. Required for the replacement of the diacylglycerol moiety by ceramides during GPI-anchor maturation..
Protein Sequence MLIINGKIIPIAHTICAFSAFFAALVTGYSLHFHKIVTNAHYTYPDEWFPSVSATIGDRYPERSIFQILIALTAFPRFLLLLGHYYLNQSKVCFLVGVLRTVSCGGWVYITSTDDHDIHDIFMITYIVLTLPWDIMITRYSSPLTSKNKGLTATIFFGTLFPMIYWYIQHSVQQRAGAYSIYAYFEWSLILLDIAFDAFAYADFKKIDIVLAFNEKPGNTSFFQIRDSSPINYGEEKSSELQKSGEKKVEKEKPVARSATGSYFRFDSFFYLLTNIFNGFLFWSNVTSLLCSIWHFPLWYMGISGYEAAILGYLGPIFLYLPFVSEAFTQYGVLLGGIIAIGAYIVQMPELRLISVAVGTSITVATFVQNLRYITNAETSFSFALTWLLGLVASVILKMGFYTNNPTWVILDERNGGYNKTALVLTVLFGMLSPYVNSINFEGKRNAQAKSASLIGKLFLAVGFGSLLFGIHQLLTDSSTTIYWAWEGYNESHGPLPWPWGALTCTVMLFASLSSVKFMGKPLVPCLLLLISTAVLSARSITQWPKYIFGGLLYAIAMLWLVPSYFSALGQVQNIWVYVLSFSVYIIFVLAHVWVVAYAFVPMGWVLREKIETVLAFSSTFIIIGALTCKNLNIQLVTMGKKFFIYVFFFAVALLSLTARFVYDIRPTGIPQPYHPDSQLITAGIWTIHFGLDNDMWASEDRMINLIKDMELDVVGLLETDTQRITMGNRDLTSKLAHDLNMYADFGPGPNKHTWGCVLLSKFPIVNSTHHLLPSPVGELAPAIHATLQTYNDTLVDVFVFHSGQEEDEEDRRLQSNYMAKLMGNTTRPAILLSYLVVDPGEGNYNTYVSETSGMHDIDPSDDDRWCEYILYRGLRRTGYARVARGTITDTELQVGKFQVLSEQALVEHSDSMYEYGHMSEPEYEDMKFPDKFLGEGERGHFYHVFDEPRYYL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
228PhosphorylationSFFQIRDSSPINYGE
CCEEEECCCCCCCCC		28.3228889911
229PhosphorylationFFQIRDSSPINYGEE
CEEEECCCCCCCCCC		33.8023749301
237UbiquitinationPINYGEEKSSELQKS
CCCCCCCCCHHHHHH		55.7923749301
237AcetylationPINYGEEKSSELQKS
CCCCCCCCCHHHHHH		55.7924489116
419N-linked_GlycosylationDERNGGYNKTALVLT
ECCCCCCCHHHHHHH		38.18-
490N-linked_GlycosylationYWAWEGYNESHGPLP
EEEECCCCCCCCCCC		55.97-
767N-linked_GlycosylationLSKFPIVNSTHHLLP
EECCCCCCCCCCCCC		41.74-
792N-linked_GlycosylationHATLQTYNDTLVDVF
HHHHHHCCCCEEEEE		38.90-
825N-linked_GlycosylationYMAKLMGNTTRPAIL
HHHHHCCCCCCCEEE		25.06-
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of CWH43_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of CWH43_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of CWH43_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
BCK2_YEASTBCK2genetic
11427965
SMI1_YEASTSMI1genetic
10206705
KPC1_YEASTPKC1genetic
11427965
GUP1_YEASTGUP1genetic
16269340
AGP1_YEASTAGP1genetic
16269340
PMT2_YEASTPMT2genetic
16269340
CWH41_YEASTCWH41genetic
16269340
PMT1_YEASTPMT1genetic
16269340
OSH1_YEASTSWH1genetic
16269340
ATC3_YEASTDRS2genetic
16269340
CWH43_YEASTCWH43physical
17761529
GGPPS_YEASTBTS1genetic
19325107
ATC3_YEASTDRS2genetic
19325107
ALG5_YEASTALG5genetic
19325107
ARP6_YEASTARP6genetic
19325107
CALX_YEASTCNE1genetic
19325107
ALG10_YEASTDIE2genetic
19325107
GET3_YEASTGET3genetic
19325107
GOSR1_YEASTGOS1genetic
19325107
TRS85_YEASTTRS85genetic
19325107
TRS65_YEASTTRS65genetic
19325107
LEM3_YEASTLEM3genetic
19325107
MNN2_YEASTMNN2genetic
19325107
PMT1_YEASTPMT1genetic
19325107
SAC7_YEASTSAC7genetic
19325107
SPC2_YEASTSPC2genetic
19325107
TLG2_YEASTTLG2genetic
19325107
UFD2_YEASTUFD2genetic
19325107
VPS51_YEASTVPS51genetic
19325107
VPS52_YEASTVPS52genetic
19325107
VPS53_YEASTVPS53genetic
19325107
VPS54_YEASTVPS54genetic
19325107
VPS74_YEASTVPS74genetic
19325107
SLG1_YEASTSLG1genetic
11427965
RHO1_YEASTRHO1genetic
11427965
SMI1_YEASTSMI1genetic
11427965
GUP1_YEASTGUP1genetic
23891562
OST6_YEASTOST6genetic
23891562
PMT2_YEASTPMT2genetic
23891562
PMT1_YEASTPMT1genetic
23891562
TRS65_YEASTTRS65genetic
23891562
GLU2A_YEASTROT2genetic
23891562
CWH41_YEASTCWH41genetic
23891562
CALX_YEASTCNE1genetic
23891562
ECM33_YEASTECM33genetic
23891562
OST3_YEASTOST3genetic
23891562
VPS27_YEASTVPS27genetic
23891562
PLMT_YEASTOPI3genetic
23891562
VPS74_YEASTVPS74genetic
23891562
GLO3_YEASTGLO3genetic
23891562
ERV14_YEASTERV14genetic
23891562
TLG2_YEASTTLG2genetic
23891562
RUD3_YEASTRUD3genetic
23891562
GPI3_YEASTSPT14genetic
23891562
VPS8_YEASTVPS8genetic
23891562
VPS38_YEASTVPS38genetic
23891562
VPS17_YEASTVPS17genetic
23891562
CCW12_YEASTCCW12genetic
23891562
PACC_YEASTRIM101genetic
23891562
PGA3_YEASTPGA3genetic
23891562
SMI1_YEASTSMI1genetic
27708008
KPC1_YEASTPKC1genetic
27708008
GPI18_YEASTGPI18genetic
27708008
CDC37_YEASTCDC37genetic
27708008
GPI8_YEASTGPI8genetic
27708008
GPI17_YEASTGPI17genetic
27708008
STT3_YEASTSTT3genetic
27708008
GPI10_YEASTGPI10genetic
27708008
SMD1_YEASTSMD1genetic
27708008
YIP1_YEASTYIP1genetic
27708008
SYMC_YEASTMES1genetic
27708008
GPI16_YEASTGPI16genetic
27708008
GWT1_YEASTGWT1genetic
27708008
CDC91_YEASTGAB1genetic
27708008
UTP15_YEASTUTP15genetic
27708008
SEC63_YEASTSEC63genetic
27708008
SEC62_YEASTSEC62genetic
27708008
FUN19_YEASTFUN19genetic
27708008
CALX_YEASTCNE1genetic
27708008
PYC2_YEASTPYC2genetic
27708008
MTC4_YEASTMTC4genetic
27708008
RGD1_YEASTRGD1genetic
27708008
ACK1_YEASTACK1genetic
27708008
MKC7_YEASTMKC7genetic
27708008
CWH41_YEASTCWH41genetic
27708008
MRM2_YEASTMRM2genetic
27708008
MED5_YEASTNUT1genetic
27708008
SPO74_YEASTSPO74genetic
27708008
FYV8_YEASTFYV8genetic
27708008
SLT2_YEASTSLT2genetic
27708008
SDS3_YEASTSDS3genetic
27708008
OM45_YEASTOM45genetic
27708008
ATG32_YEASTATG32genetic
27708008
BCK1_YEASTBCK1genetic
27708008
SUMT_YEASTMET1genetic
27708008
CSF1_YEASTCSF1genetic
27708008
VPS9_YEASTVPS9genetic
27708008
SOK2_YEASTSOK2genetic
27708008
MKS1_YEASTMKS1genetic
27708008
NST1_YEASTNST1genetic
27708008
PFD4_YEASTGIM3genetic
27708008
SIN3_YEASTSIN3genetic
27708008
BRR1_YEASTBRR1genetic
27708008
SPEE_YEASTSPE3genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of CWH43_YEAST

loading...

Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"A multidimensional chromatography technology for in-depthphosphoproteome analysis.";
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.;
Mol. Cell. Proteomics 7:1389-1396(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-229, AND MASSSPECTROMETRY.

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory