| UniProt ID | GUP1_YEAST | |
|---|---|---|
| UniProt AC | P53154 | |
| Protein Name | Glycerol uptake protein 1 | |
| Gene Name | GUP1 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 560 | |
| Subcellular Localization |
Membrane Multi-pass membrane protein . |
|
| Protein Description | Involved in active uptake of glycerol driven by electrogenic proton symport.. | |
| Protein Sequence | MSLISILSPLITSEGLDSRIKPSPKKDASTTTKPSLWKTTEFKFYYIAFLVVVPLMFYAGLQASSPENPNYARYERLLSQGWLFGRKVDNSDSQYRFFRDNFALLSVLMLVHTSIKRIVLYSTNITKLRFDLIFGLIFLVAAHGVNSIRILAHMLILYAIAHVLKNFRRIATISIWIYGISTLFINDNFRAYPFGNICSFLSPLDHWYRGIIPRWDVFFNFTLLRVLSYNLDFLERWENLQKKKSPSYESKEAKSAILLNERARLTAAHPIQDYSLMNYIAYVTYTPLFIAGPIITFNDYVYQSKHTLPSINFKFIFYYAVRFVIALLSMEFILHFLHVVAISKTKAWENDTPFQISMIGLFNLNIIWLKLLIPWRLFRLWALLDGIDTPENMIRCVDNNYSSLAFWRAWHRSYNKWVVRYIYIPLGGSKNRVLTSLAVFSFVAIWHDIELKLLLWGWLIVLFLLPEIFATQIFSHYTDAVWYRHVCAVGAVFNIWVMMIANLFGFCLGSDGTKKLLSDMFCTVSGFKFVILASVSLFIAVQIMFEIREEEKRHGIYLKC | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 2 | Phosphorylation | ------MSLISILSP ------CCHHHHHHH | 34.12 | 28132839 | |
| 5 | Phosphorylation | ---MSLISILSPLIT ---CCHHHHHHHHHC | 23.83 | 28132839 | |
| 8 | Phosphorylation | MSLISILSPLITSEG CCHHHHHHHHHCCCC | 18.91 | 19823750 | |
| 12 | Phosphorylation | SILSPLITSEGLDSR HHHHHHHCCCCCCCC | 28.54 | 28132839 | |
| 13 | Phosphorylation | ILSPLITSEGLDSRI HHHHHHCCCCCCCCC | 23.75 | 28132839 | |
| 18 | Phosphorylation | ITSEGLDSRIKPSPK HCCCCCCCCCCCCCC | 40.73 | 28132839 | |
| 23 | Phosphorylation | LDSRIKPSPKKDAST CCCCCCCCCCCCCCC | 44.33 | 19823750 | |
| 95 | Phosphorylation | VDNSDSQYRFFRDNF CCCCHHHCHHHHHHH | 17.22 | 28889911 | |
| 106 | Phosphorylation | RDNFALLSVLMLVHT HHHHHHHHHHHHHHH | 17.66 | 28889911 | |
| 251 | Ubiquitination | KSPSYESKEAKSAIL CCCCCCCHHHHHHHH | 50.15 | 23749301 | |
| 254 | Ubiquitination | SYESKEAKSAILLNE CCCCHHHHHHHHHCH | 41.32 | 23749301 | |
| 255 | Phosphorylation | YESKEAKSAILLNER CCCHHHHHHHHHCHH | 27.82 | 24930733 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of GUP1_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of GUP1_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of GUP1_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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| Phosphorylation | |
| Reference | PubMed |
| "A multidimensional chromatography technology for in-depthphosphoproteome analysis."; Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.; Mol. Cell. Proteomics 7:1389-1396(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-8, AND MASSSPECTROMETRY. | |
