dbPTM

YD387_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	YD387_YEAST
UniProt AC	Q04162
Protein Name	Probable metabolite transport protein YDR387C
Gene Name	YDR387C
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	555
Subcellular Localization	Membrane Multi-pass membrane protein.
Protein Description
Protein Sequence	MSTDESEDVYSDLYSIISQVTSNTANDIEQLPYALTFKTSLIFVGATIGGLLFGYDTGVISGVLLSLKPEDLSLVVLTDVQKELITSSTSVGSFFGSILAFPLADRYGRRITLAICCSIFILAAIGMAIARTLTFLICGRLLVGIAVGVSAQCVPLFLSEISPSRIRGFMLTLNIIAITGGQLVSYVIASLMKEIDNSWRYLFALSAIPAILFLSILDFIPESPRWSISKGDILYTRDSLRMLYPTASTYHVNSKIKQLIIELDKLRLYEDASEPLLVQSQSVIRYMDSSTSGTLSPPNIKRLSSNTERTSNTMSSSSAYLSALRGPAPNGALASNKKKRHRMEPRTIRALIVGCMLMFFQQITGFNAFMYYAAIIFSKFNIKNPLLPPILIASTNFIFTFFAMYTMDSLGRRAILLRTILIMTVGLLLCSVGFGHDQVNLLLISVVIYVAAYASAMGSVPWTCVEFLPLNRRSFGASCIACTNWLTNAFVSMTYLSTINTIGDENTMLIFAFFTVCAWFFVYFWYPEVKGLSLEEVGRVFDNGIDVHYVFRTYH

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
273	Phosphorylation	LRLYEDASEPLLVQS CCCCCCCCCCCEEEC	52.66	27214570
286	Phosphorylation	QSQSVIRYMDSSTSG ECHHHHCCCCCCCCC	8.31	22890988
289	Phosphorylation	SVIRYMDSSTSGTLS HHHCCCCCCCCCCCC	20.98	22890988
290	Phosphorylation	VIRYMDSSTSGTLSP HHCCCCCCCCCCCCC	23.48	22890988
291	Phosphorylation	IRYMDSSTSGTLSPP HCCCCCCCCCCCCCC	34.82	22890988
292	Phosphorylation	RYMDSSTSGTLSPPN CCCCCCCCCCCCCCC	31.56	22890988
294	Phosphorylation	MDSSTSGTLSPPNIK CCCCCCCCCCCCCCH	24.67	22890988
296	Phosphorylation	SSTSGTLSPPNIKRL CCCCCCCCCCCCHHC	37.84	22890988
301	Ubiquitination	TLSPPNIKRLSSNTE CCCCCCCHHCCCCCC	54.66	23749301

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of YD387_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of YD387_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of YD387_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ADY4_YEAST	ADY4	genetic	27708008
YM24_YEAST	YMR147W	genetic	27708008
MRX3_YEAST	YBL095W	genetic	27708008
YCA2_YEAST	YCL002C	genetic	27708008
ATG22_YEAST	ATG22	genetic	27708008
MTU1_YEAST	SLM3	genetic	27708008
GPR1_YEAST	GPR1	genetic	27708008
RL13A_YEAST	RPL13A	genetic	27708008
TPS2_YEAST	TPS2	genetic	27708008
UBC13_YEAST	UBC13	genetic	27708008
RPA14_YEAST	RPA14	genetic	27708008
RAD9_YEAST	RAD9	genetic	27708008
IES5_YEAST	IES5	genetic	27708008
FAR7_YEAST	FAR7	genetic	27708008
PYC1_YEAST	PYC1	genetic	27708008
DBP3_YEAST	DBP3	genetic	27708008
MDM34_YEAST	MDM34	genetic	27708008
RL26B_YEAST	RPL26B	genetic	27708008
6PGD2_YEAST	GND2	genetic	27708008
PRY1_YEAST	PRY1	genetic	27708008
CBT1_YEAST	CBT1	genetic	27708008
XYL2_YEAST	XYL2	genetic	27708008
LAM6_YEAST	YLR072W	genetic	27708008
ACE2_YEAST	ACE2	genetic	27708008
YL149_YEAST	YLR149C	genetic	27708008
VRP1_YEAST	VRP1	genetic	27708008
DIC1_YEAST	DIC1	genetic	27708008
YL415_YEAST	YLR415C	genetic	27708008
GBLP_YEAST	ASC1	genetic	27708008
RAD14_YEAST	RAD14	genetic	27708008
HDA1_YEAST	HDA1	genetic	27708008
PP2A4_YEAST	PPG1	genetic	27708008
YO223_YEAST	DSC3	genetic	27708008
RDL2_YEAST	RDL2	genetic	27708008
SRL4_YEAST	SRL4	genetic	27708008
SUR1_YEAST	SUR1	genetic	27708008
SAM3_YEAST	SAM3	genetic	27708008
CISY3_YEAST	CIT3	genetic	27708008
AP1G1_YEAST	APL4	genetic	27708008

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of YD387_YEAST

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"A multidimensional chromatography technology for in-depthphosphoproteome analysis."; Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.; Mol. Cell. Proteomics 7:1389-1396(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-273, AND MASSSPECTROMETRY.	18407956 [Abstract]