dbPTM

MRX3_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	MRX3_YEAST
UniProt AC	P38172
Protein Name	MIOREX complex component 3 {ECO:0000305\|PubMed:25683707}
Gene Name	MRX3 {ECO:0000303\|PubMed:25683707}
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	270
Subcellular Localization	Mitochondrion .
Protein Description	Component of MIOREX complexes, large expressome-like assemblies of ribosomes with factors involved in all the steps of post-transcriptional gene expression..
Protein Sequence	MSRTIPFLFKLVNRAVILPTAGFTLGVGAFVKAWPDDAGVLSLNDPQTPAELISATKSRQPMELQRVDILAQIEKSEVYNKLAQDEKMHHVLFSEKIPSGHREYHVGQGLLFGKGKLEIDPLVFHDVNHGELTVIYHLGAELGNRDGNVHKGLLSLLLDEALCYCGFPLLPSKRGVTARLSLEFFEDIPVDTTIILKANVKEIKGRKCIIEGHLEQFPLEVSSRNGTRSWNLPHIWGFNHKQEMAKKFAKANCILVEPTWFKYFKWLDMF

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	Reference
42	Phosphorylation	PDDAGVLSLNDPQTP CCCCCEECCCCCCCH	27214570
48	Phosphorylation	LSLNDPQTPAELISA ECCCCCCCHHHHHHH	27214570
54	Phosphorylation	QTPAELISATKSRQP CCHHHHHHHCCCCCC	27214570

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of MRX3_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of MRX3_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of MRX3_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
NPL4_YEAST	NPL4	genetic	27708008
RMD9L_YEAST	YBR238C	genetic	27708008
RS29B_YEAST	RPS29B	genetic	27708008
FMP16_YEAST	FMP16	genetic	27708008
STP1_YEAST	STP1	genetic	27708008
NKP2_YEAST	NKP2	genetic	27708008
SOK2_YEAST	SOK2	genetic	27708008
IMP2_YEAST	IMP2	genetic	27708008
PUB1_YEAST	PUB1	genetic	27708008

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of MRX3_YEAST

Related Literatures of Post-Translational Modification