NKP2_YEAST - dbPTM
NKP2_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID NKP2_YEAST
UniProt AC Q06162
Protein Name Inner kinetochore subunit NKP2 {ECO:0000305}
Gene Name NKP2
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 153
Subcellular Localization Nucleus . Chromosome, centromere, kinetochore . Associated with kinetochores (PubMed:12408861).
Protein Description Component of the kinetochore, a multiprotein complex that assembles on centromeric DNA and attaches chromosomes to spindle microtubules, mediating chromosome segregation and sister chromatid segregation during meiosis and mitosis. Component of the inner kinetochore constitutive centromere-associated network (CCAN), which serves as a structural platform for outer kinetochore assembly..
Protein Sequence MNSEQLLHNYVSDSLLTTLISFQEFKQQLQSYTSDEQQLQHWYELLQARDARVTSELEARIKQFFITLRSRLLRFLESEQLSHSLSLETLIDALYKINDLLQQRLQILDDAIQEKTSELAEFENMVRSPSAGDNAIPGLLQIIQSYINLLEEN
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster

Oops, there are no PTM records of NKP2_YEAST !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources
-KUbiquitinationE3 ubiquitin ligaseRSP5P39940
PMID:22199232

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of NKP2_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of NKP2_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
NKP1_YEASTNKP1physical
10688190
HMT1_YEASTHMT1physical
16554755
NKP1_YEASTNKP1physical
16554755
COPB2_YEASTSEC27physical
16554755
AME1_YEASTAME1physical
17634282
AHC2_YEASTAHC2physical
17634282
ATG20_YEASTATG20physical
17634282
LIC4_YEASTATC1physical
17634282
MED21_YEASTSRB7physical
17634282
NKP1_YEASTNKP1physical
17634282
LCP5_YEASTLCP5physical
17634282
MED3_YEASTPGD1physical
17634282
OKP1_YEASTOKP1physical
17634282
YL031_YEASTYLR031Wphysical
17634282
PHO23_YEASTPHO23physical
17634282
AHC1_YEASTAHC1physical
17634282
PALA_YEASTRIM20physical
17634282
BBP1_YEASTBBP1physical
17634282
MCM16_YEASTMCM16physical
17634282
NOT5_YEASTNOT5physical
17634282
MDM36_YEASTMDM36physical
17634282
IMDH4_YEASTIMD4physical
18467557
IMDH3_YEASTIMD3physical
18467557
NKP1_YEASTNKP1physical
18719252
NKP1_YEASTNKP1genetic
24385296
MCM22_YEASTMCM22genetic
24385296
CHL4_YEASTCHL4genetic
24385296
CTF3_YEASTCTF3genetic
24385296
MCM16_YEASTMCM16genetic
24385296
CTF19_YEASTCTF19genetic
24385296
MCM21_YEASTMCM21genetic
24385296
IML3_YEASTIML3genetic
24385296
AME1_YEASTAME1genetic
27708008
SNU23_YEASTSNU23genetic
27708008
CDC4_YEASTCDC4genetic
27708008
OKP1_YEASTOKP1genetic
27708008
MED6_YEASTMED6genetic
27708008
CDC23_YEASTCDC23genetic
27708008
DSN1_YEASTDSN1genetic
27708008
TAD2_YEASTTAD2genetic
27708008
MIF2_YEASTMIF2genetic
27708008
SPC24_YEASTSPC24genetic
27708008
CBF3B_YEASTCEP3genetic
27708008
PSB5_YEASTPRE2genetic
27708008
BUR1_YEASTSGV1genetic
27708008
GPR1_YEASTGPR1genetic
27708008
MON1_YEASTMON1genetic
27708008
NST1_YEASTNST1genetic
27708008
SFL1_YEASTSFL1genetic
27708008
USBP1_HUMANUSHBP1physical
27107014

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of NKP2_YEAST

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Related Literatures of Post-Translational Modification

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