USBP1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: USBP1_HUMAN
• UniProt AC: Q8N6Y0
• Protein Name: Usher syndrome type-1C protein-binding protein 1
• Gene Name: USHBP1 {ECO:0000312|EMBL:AAH27910.1}
• Organism: Homo sapiens (Human).
• Sequence Length: 703
• Protein Sequence: MSARATRPRSRRGRHAPPGELDPVAESSEEVEAASGSSKPSFAPPPVSSGLEQLGPMEEVSGQGLGSRTDKKMDGGSGRELASAPEVPHKPAVEAHQAPEAALQYKETVPPGNGAPDVFQTLQHTLSSLEAAAAAWRHQPPSHSGPMEFEGTSEGGAGSLGKQEGAGSCQREAARLAERNAWLRLALSSREDELVRTQASLEAIRAEKETLQKEVQELQDSLLRLEPCPHLSHNQAGGSGSGSSSSEADREPWETQDSFSLAHPLLRRLRSHSSTQILGSLPNQPLSPEMHIMEAQMEQLRGSIEKLKCFNRLLSAVLQGYKGRCEGLSMQLGQREAEATALHLALQYSEHCEEAYRVLLALREADSGAGDEAPMSDLQAAEKEAWRLLAQEEAAMDAGAQQNPQPSPEGSSVDKPTPQEVAFQLRSYVQRLQERRSLMKILSEPGPTLAPMPTVPRAEAMVQAILGTQAGPALPRLEKTQIQQDLVAAREALADLMLRLQLVRREKRGLELREAALRALGPAHVLLLEQLRWERAELQAGGANSSGGHSSGGGSSGDEEEWYQGLPAVPGGTSGIDGGQVGRAWDPEKLAQELAASLTRTLDLQEQLQSLRRELEQVAQKGRARRSQSAELNRDLCKAHSALVLAFRGAHRKQEEQRRKLEQQMALMEAQQAEEVAVLEATARALGKPRPPLPPPQLGDTFL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
83	Phosphorylation	GSGRELASAPEVPHK CCCCCCCCCCCCCCC	57.91	24719451
221	Phosphorylation	EVQELQDSLLRLEPC HHHHHHHHHHCCCCC	19.15	24719451
315	Phosphorylation	KCFNRLLSAVLQGYK HHHHHHHHHHHCHHC	22.41	-
322	Acetylation	SAVLQGYKGRCEGLS HHHHCHHCCCHHHHH	46.86	19815655
340	Phosphorylation	GQREAEATALHLALQ CHHHHHHHHHHHHHH	22.66	30177828
348	Phosphorylation	ALHLALQYSEHCEEA HHHHHHHHHHHHHHH	19.51	30177828
349	Phosphorylation	LHLALQYSEHCEEAY HHHHHHHHHHHHHHH	14.11	30177828
356	Phosphorylation	SEHCEEAYRVLLALR HHHHHHHHHHHHHHH	12.44	30177828
627	Phosphorylation	QKGRARRSQSAELNR HHHHHHHHHHHHHHH	23.96	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of USBP1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of USBP1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of USBP1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
DYDC1_HUMAN	DYDC1	physical	16189514
FBF1_HUMAN	FBF1	physical	16189514
FATE1_HUMAN	FATE1	physical	16189514
USBP1_HUMAN	USHBP1	physical	16189514
CA216_HUMAN	C1orf216	physical	16189514
KANL1_HUMAN	KANSL1	physical	16189514
EXOC8_HUMAN	EXOC8	physical	16189514
CC120_HUMAN	CCDC120	physical	16189514
USH1C_HUMAN	USH1C	physical	11311560
SRTD3_HUMAN	SERTAD3	physical	19060904
USBP1_HUMAN	USHBP1	physical	25416956
FBF1_HUMAN	FBF1	physical	25416956
KLC4_HUMAN	KLC4	physical	25416956
CC120_HUMAN	CCDC120	physical	25416956
IFT20_HUMAN	IFT20	physical	25416956
UBX11_HUMAN	UBXN11	physical	25416956
ZN765_HUMAN	ZNF765	physical	25416956
INT4_HUMAN	INTS4	physical	25416956
HAUS1_HUMAN	HAUS1	physical	25416956
K1C40_HUMAN	KRT40	physical	25416956
CA216_HUMAN	C1orf216	physical	25416956
CC148_HUMAN	CCDC148	physical	25416956
DYDC1_HUMAN	DYDC1	physical	25416956
KLC3_HUMAN	KLC3	physical	25416956
CCD24_HUMAN	CCDC24	physical	25416956
CF206_HUMAN	C6orf165	physical	25416956
ZN483_HUMAN	ZNF483	physical	25416956
CC116_HUMAN	CCDC116	physical	25416956
TXLNB_HUMAN	TXLNB	physical	25416956
TXLNA_HUMAN	TXLNA	physical	25416956
S14L4_HUMAN	SEC14L4	physical	25416956
K2C79_HUMAN	KRT79	physical	25416956
KLH38_HUMAN	KLHL38	physical	25416956
CENPP_HUMAN	CENPP	physical	25416956

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.