CC148_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CC148_HUMAN
• UniProt AC: Q8NFR7
• Protein Name: Coiled-coil domain-containing protein 148
• Gene Name: CCDC148
• Organism: Homo sapiens (Human).
• Sequence Length: 591
• Protein Sequence: MCAASASPDNLVFHMKNEMRNIKYKPVDYQQLRALTEAKKLASASAKLKIRKAMLTSKLSKEQTLIKQHKQVWWQEYQRLNEVRCKMESEIKSLLNEENIGNECLCDLTNFEQELSEQQCTYLKNVINPIQQLRADLKYRQHHTLQHSHPHIEFNSMKVLEEVDFVKKQLKTVFERLRLEQQRIENDLSDWSIKILDHSLEEKTNPLSELPIELESLECPYPDLKSSILSEFYKFTQKYQKKLQDFNLQLEDIYRNCQLSEEDHWIYQAILDQYPGDLFGRRTLYLDMLQRYFPHKSRHDLVEHEKYCDQYRFAIEQQNILISNWNKNKKDFIQKAVLTLTEACATHEMESMLAKDKKKQQELCADLKAKVRQWRAHQEEVARLEMEISARRREKEEEKEKLWKKKELLQRAEKKKKIKKYWAKKKQKWQEMEMRDLQRLEELKKLIAEQSLKDRERVKYRQELLERRLMEKKEVALQEAHEDKERARRLEALRKQVAVVAQFDPVRMMSDTMASKARMGIEIEEEFILQKPLFTLNTYNEQQIISDPRLRFELALREAGLHRTLYAKEILPKISPQKPPRKDMESTVFKI

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
7	Phosphorylation	-MCAASASPDNLVFH -CCCCCCCCCCEEEE	30.23	29116813
57	Phosphorylation	IRKAMLTSKLSKEQT HHHHHHHHCCCHHHH	27.86	24505115
192	Phosphorylation	ENDLSDWSIKILDHS HCCCCHHHHHHHHCC	20.99	-
239	Phosphorylation	FYKFTQKYQKKLQDF HHHHHHHHHHHHHHH	18.75	28842319
389	Phosphorylation	ARLEMEISARRREKE HHHHHHHHHHHHHHH	11.47	30108239
419	Acetylation	AEKKKKIKKYWAKKK HHHHHHHHHHHHHHH	49.00	11306805
421	Phosphorylation	KKKKIKKYWAKKKQK HHHHHHHHHHHHHHH	12.95	26657352
451	Phosphorylation	KKLIAEQSLKDRERV HHHHHHCCCCHHHHH	28.97	23909892
575	Phosphorylation	KEILPKISPQKPPRK HHHHCCCCCCCCCCC	27.66	24719451
586	Phosphorylation	PPRKDMESTVFKI-- CCCCCCCCCCEEC--	24.19	24719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CC148_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CC148_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CC148_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SAT1_HUMAN	SAT1	physical	19060904
SG1D1_HUMAN	SCGB1D1	physical	26186194
TRFL_HUMAN	LTF	physical	26186194
SG2A1_HUMAN	SCGB2A1	physical	26186194
LACRT_HUMAN	LACRT	physical	26186194
TEX9_HUMAN	TEX9	physical	26186194
SG2A1_HUMAN	SCGB2A1	physical	28514442
TEX9_HUMAN	TEX9	physical	28514442
TRFL_HUMAN	LTF	physical	28514442
LACRT_HUMAN	LACRT	physical	28514442
SG1D1_HUMAN	SCGB1D1	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.