| UniProt ID | KLH38_HUMAN | |
|---|---|---|
| UniProt AC | Q2WGJ6 | |
| Protein Name | Kelch-like protein 38 | |
| Gene Name | KLHL38 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 581 | |
| Subcellular Localization | ||
| Protein Description | ||
| Protein Sequence | MDEESLDGLLFKDHDFSSDLLRQLNSLRQSRILTDVSICAGAREIPCHRNVLASSSPYFRAMFCSSFREKSEAKVQLKGIDPPTLDQIVSYVYTGEAHIATDNVLPVMEAASMLQFPKLFEACSSYLQSQLAPSNCLGMIRLSEILSCETLKKKAREVALTSFPEVAASADLKELCALELRDYLGDDGLCGEEEKVFEALMVWIKHDLQARKRYMQELFKQVRLQYIHPAFFHHFIANDALLQSSPACQIILETAKRQMFSLCGTTVPDCKLLLHVPPRNSYQDFLILLGGRKDSQQTTRDVLLYSKQTGQWQSLAKLPTRLYKASAITLHRSIYVLGGMAVSSGRSLVSHNVYIFSLKLNQWRLGEPMLVARYSHRSTAHKNFIFSIGGIGEGQELMGSMERYDSICNVWESMASMPVGVLHPAVAVKDQRLYLFGGEDIMQNPVRLIQVYHISRNSWFKMETRMIKNVCAPAVVLGERIVIVGGYTRRILAYDPQSNKFVKCADMKDRRMHHGATVMGNKLYVTGGRRLTTDCNIEDSASFDCYDPETDTWTSQGQLPHKLFDHACLTLQCIPRTSGLP | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 30 | Phosphorylation | QLNSLRQSRILTDVS HHHHHHHHCCHHCHH | 18.17 | 26091039 | |
| 161 | Phosphorylation | KAREVALTSFPEVAA HHHHHHHHCCHHHHH | 20.70 | - | |
| 162 | Phosphorylation | AREVALTSFPEVAAS HHHHHHHCCHHHHHC | 39.39 | - | |
| 305 | Phosphorylation | TTRDVLLYSKQTGQW CHHHHHEEECCCCCC | 15.06 | 25690035 | |
| 306 | Phosphorylation | TRDVLLYSKQTGQWQ HHHHHEEECCCCCCH | 20.46 | 25690035 | |
| 326 | Phosphorylation | PTRLYKASAITLHRS CCHHHHHHHHHHCCE | 18.95 | 30576142 | |
| 335 | Phosphorylation | ITLHRSIYVLGGMAV HHHCCEEEEECCEEE | 7.29 | 30576142 | |
| 347 | Phosphorylation | MAVSSGRSLVSHNVY EEECCCCCCEECCEE | 36.33 | 30576142 | |
| 413 | Phosphorylation | SICNVWESMASMPVG HHHHHHHHHHCCCCC | 12.16 | - | |
| 503 | Methylation | PQSNKFVKCADMKDR CCCCCEEEECCCCCC | 27.17 | - | |
| 508 | Methylation | FVKCADMKDRRMHHG EEEECCCCCCCCCCC | 48.94 | - | |
| 526 | Phosphorylation | MGNKLYVTGGRRLTT ECCEEEEECCCCCCC | 21.99 | 27251275 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of KLH38_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of KLH38_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of KLH38_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| KR107_HUMAN | KRTAP10-7 | physical | 25416956 | |
| KR109_HUMAN | KRTAP10-9 | physical | 25416956 | |
| KR108_HUMAN | KRTAP10-8 | physical | 25416956 | |
| KR103_HUMAN | KRTAP10-3 | physical | 25416956 | |
| NT2NL_HUMAN | NOTCH2NL | physical | 25416956 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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