UBC13_YEAST - dbPTM
UBC13_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID UBC13_YEAST
UniProt AC P52490
Protein Name Ubiquitin-conjugating enzyme E2 13
Gene Name UBC13
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 153
Subcellular Localization
Protein Description Has a role in the DNA error-free postreplication repair (PRR) pathway. The UBC13/MMS2 heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'..
Protein Sequence MASLPKRIIKETEKLVSDPVPGITAEPHDDNLRYFQVTIEGPEQSPYEDGIFELELYLPDDYPMEAPKVRFLTKIYHPNIDRLGRICLDVLKTNWSPALQIRTVLLSIQALLASPNPNDPLANDVAEDWIKNEQGAKAKAREWTKLYAKKKPE
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
14AcetylationRIIKETEKLVSDPVP
HHHHHHHHHHCCCCC		62.7024489116
74UbiquitinationPKVRFLTKIYHPNID
CCEEEEHHCCCCCHH		43.3323749301
74AcetylationPKVRFLTKIYHPNID
CCEEEEHHCCCCCHH		43.3324489116
92UbiquitinationRICLDVLKTNWSPAL
HHHHHHHHHCCCHHH		39.3923749301
92AcetylationRICLDVLKTNWSPAL
HHHHHHHHHCCCHHH		39.3924489116
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of UBC13_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of UBC13_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of UBC13_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
MMS2_YEASTMMS2physical
11805837
RAD18_YEASTRAD18physical
11805837
ARO9_YEASTARO9physical
11805837
UBA1_YEASTUBA1physical
11805837
ORN_YEASTREX2physical
11805837
RAD5_YEASTRAD5physical
10880451
MMS2_YEASTMMS2physical
12496280
MMS2_YEASTMMS2physical
10880451
MMS2_YEASTMMS2physical
11369780
MMS2_YEASTMMS2physical
10089880
RAD5_YEASTRAD5physical
16224103
DPOZ_YEASTREV3genetic
10794173
SRS2_YEASTSRS2genetic
11522817
MMS2_YEASTMMS2physical
16554755
SIP5_YEASTSIP5physical
16554755
RV161_YEASTRVS161genetic
17314980
VPS8_YEASTVPS8genetic
17314980
PLPHP_YEASTYBL036Cgenetic
17314980
RPC10_YEASTRPC11genetic
17314980
DBF4_YEASTDBF4genetic
17314980
SLA1_YEASTSLA1genetic
17314980
NUP84_YEASTNUP84genetic
17314980
MMS2_YEASTMMS2physical
18467557
COX7_YEASTCOX7physical
18467557
SIP5_YEASTSIP5physical
18467557
CEM1_YEASTCEM1physical
18467557
T2FB_YEASTTFG2physical
18467557
UEV1A_ARATHMMZ1physical
18178771
UEV1D_ARATHUEV1D-4physical
18178771
PCNA_YEASTPOL30genetic
12968183
SIZ1_YEASTSIZ1genetic
12968183
RAD23_YEASTRAD23genetic
15226437
PCNA_YEASTPOL30genetic
20385585
RAD17_YEASTRAD17genetic
20550940
SIZ1_YEASTSIZ1genetic
15989970
SRS2_YEASTSRS2genetic
15989970
SIZ1_YEASTSIZ1genetic
21362066
VMS1_YEASTVMS1genetic
21127252
KCS1_YEASTKCS1genetic
21127252
MMS2_YEASTMMS2physical
22615397
MPH1_YEASTMPH1genetic
22696213
UB2V2_DANREube2v2physical
22055568
UBI4P_YEASTUBI4physical
21771579
RAD5_YEASTRAD5physical
24674630
CHFR_HUMANCHFRphysical
24674630
UBI4P_YEASTUBI4physical
10089880
UBI4P_YEASTUBI4physical
15772086
UBC_BOVINUBCphysical
12496280
UBC13_YEASTUBC13physical
12496280
DPOZ_YEASTREV3genetic
24473148
HMO1_YEASTHMO1genetic
24473148
FUN30_YEASTFUN30genetic
25806814
UBI4P_YEASTUBI4physical
11504715
DPOZ_YEASTREV3genetic
25701288
ESA1_YEASTESA1genetic
25701288
YNG2_YEASTYNG2genetic
25701288
H2AZ_YEASTHTZ1genetic
25701288
ASK10_YEASTASK10genetic
27708008
SNF6_YEASTSNF6genetic
27708008
INO4_YEASTINO4genetic
27708008
HAP3_YEASTHAP3genetic
27708008
RS6A_YEASTRPS6Bgenetic
27708008
RS6B_YEASTRPS6Bgenetic
27708008
CLPX_YEASTMCX1genetic
27708008
BUD31_YEASTBUD31genetic
27708008
IMG2_YEASTIMG2genetic
27708008
S2538_YEASTYDL119Cgenetic
27708008
BCS1_YEASTBCS1genetic
27708008
RTR1_YEASTRTR1genetic
27708008
MED5_YEASTNUT1genetic
27708008
MED20_YEASTSRB2genetic
27708008
HTD2_YEASTHTD2genetic
27708008
MPH1_YEASTMPH1genetic
27708008
YIS7_YEASTYIR007Wgenetic
27708008
SYS1_YEASTSYS1genetic
27708008
ALY2_YEASTALY2genetic
27708008
DPOD3_YEASTPOL32genetic
27708008
MOG1_YEASTMOG1genetic
27708008
HAP4_YEASTHAP4genetic
27708008
OAC1_YEASTOAC1genetic
27708008
RM49_YEASTMRP49genetic
27708008
IRS4_YEASTIRS4genetic
27708008
RL8B_YEASTRPL8Bgenetic
27708008
UPS1_YEASTUPS1genetic
27708008
PET8_YEASTPET8genetic
27708008
HDA1_YEASTHDA1genetic
27708008
CYC2_YEASTCYC2genetic
27708008
CY1_YEASTCYT1genetic
27708008
DIA2_YEASTDIA2genetic
27708008
LIPA_YEASTLIP5genetic
27708008
REV1_YEASTREV1genetic
27708008
NCBP2_YEASTCBC2genetic
27708008
NEW1_YEASTNEW1genetic
27708008
BRR1_YEASTBRR1genetic
27708008
MED1_YEASTMED1genetic
27708008
DPOZ_YEASTREV3genetic
28334887
RAD5_YEASTRAD5physical
25690888
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of UBC13_YEAST

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Related Literatures of Post-Translational Modification

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