| UniProt ID | RTR1_YEAST | |
|---|---|---|
| UniProt AC | P40084 | |
| Protein Name | RNA polymerase II subunit B1 CTD phosphatase RTR1 | |
| Gene Name | RTR1 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 226 | |
| Subcellular Localization | Cytoplasm. Nucleus. Shuttles constitutively between the cytoplasm and the nucleus. | |
| Protein Description | RNA polymerase II subunit B1 C-terminal domain (CTD) phosphatase that dephosphorylates 'Ser-5' of the CTD and regulates RNA polymerase II during the transition from 'Ser-5' to 'Ser-2' phosphorylation.. | |
| Protein Sequence | MATIEDIKETALIPFQKHRQLSMHEAEVITLEIIGLLCDSECKDEKTLKYLGRFLTPDMYQDLVDERNLNKRCGYPLCGKSPERIRDPFSMNDTTKKFLLENNPYAYLSHYCSKFHFRCSQFYQVQLSDEALFARTGVHLFEDPEQDKHDIDFKVTLFEELLREKASEEDIKSLISGLKKLGLNPDSGTTEKDDTELEDDLSKWLAQIKIVENDNPSILGDFTRED | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 3 | Phosphorylation | -----MATIEDIKET -----CCCHHHHHHH | 24.49 | 19795423 | |
| 8 | Acetylation | MATIEDIKETALIPF CCCHHHHHHHHCCCH | 62.42 | 24489116 | |
| 17 | Acetylation | TALIPFQKHRQLSMH HHCCCHHHCCCCCHH | 40.93 | 24489116 | |
| 165 | Ubiquitination | FEELLREKASEEDIK HHHHHHHHCCHHHHH | 51.26 | 23749301 | |
| 172 | Ubiquitination | KASEEDIKSLISGLK HCCHHHHHHHHHHHH | 52.08 | 23749301 | |
| 187 | Phosphorylation | KLGLNPDSGTTEKDD HCCCCCCCCCCCCCC | 39.02 | 29136822 | |
| 189 | Phosphorylation | GLNPDSGTTEKDDTE CCCCCCCCCCCCCCH | 35.42 | 29136822 | |
| 190 | Phosphorylation | LNPDSGTTEKDDTEL CCCCCCCCCCCCCHH | 44.56 | 29136822 | |
| 192 | Ubiquitination | PDSGTTEKDDTELED CCCCCCCCCCCHHHH | 59.83 | 23749301 | |
| 195 | Phosphorylation | GTTEKDDTELEDDLS CCCCCCCCHHHHHHH | 53.24 | 29136822 | |
| 217 | Phosphorylation | IVENDNPSILGDFTR EECCCCCCHHCCCCC | 36.38 | 21440633 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of RTR1_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of RTR1_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of RTR1_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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