OCA6_YEAST - dbPTM
OCA6_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID OCA6_YEAST
UniProt AC Q12454
Protein Name Putative tyrosine-protein phosphatase OCA6
Gene Name OCA6
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 224
Subcellular Localization Cytoplasm .
Protein Description Required for replication of Brome mosaic virus (BMV)..
Protein Sequence MTLVTPLQFSTVQPNLYRGSYPREINLPFLRTLRLKYILSLTPEPLSTDPLMVKFCEENNIKTIHIKCQSERKADKTKPKIKRKKKTVPIEYDVVVRCVKFLIDKGHYPCYMHCTNGELIISLVVACMRKFSYWSTVSILNEFLVYNSSINIHERNFIENFNSEIEVDDLDIKDKVPWITVRYIARTATESKDELRVDDANASEKVARVSSVSNSLPKLKFHSM
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
2Phosphorylation------MTLVTPLQF
------CCCCCCCCE		29.9028889911
5Phosphorylation---MTLVTPLQFSTV
---CCCCCCCCEECC		22.7628889911
10PhosphorylationLVTPLQFSTVQPNLY
CCCCCCEECCCCCCC		18.0830377154
17PhosphorylationSTVQPNLYRGSYPRE
ECCCCCCCCCCCCCC		21.4028889911
187PhosphorylationTVRYIARTATESKDE
EHHHHEECCCCCCCC		28.9830377154
210PhosphorylationSEKVARVSSVSNSLP
CHHHHHHHHHCCCCC		21.3322369663
211PhosphorylationEKVARVSSVSNSLPK
HHHHHHHHHCCCCCC		27.0622369663
213PhosphorylationVARVSSVSNSLPKLK
HHHHHHHCCCCCCCC		23.7321440633
215PhosphorylationRVSSVSNSLPKLKFH
HHHHHCCCCCCCCCC		38.2422369663
223PhosphorylationLPKLKFHSM------
CCCCCCCCC------		29.3521440633
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of OCA6_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of OCA6_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of OCA6_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
GIS1_YEASTGIS1genetic
19269370
SIW14_YEASTSIW14genetic
21409566
RLA1_YEASTRPP1Agenetic
27708008
ADY4_YEASTADY4genetic
27708008
IZH2_YEASTIZH2genetic
27708008
PER1_YEASTPER1genetic
27708008
THRC_YEASTTHR4genetic
27708008
CSM1_YEASTCSM1genetic
27708008
ESC2_YEASTESC2genetic
27708008
URC2_YEASTURC2genetic
27708008
SAK1_YEASTSAK1genetic
27708008
KA122_YEASTKAP122genetic
27708008
YGI1_YEASTYGL081Wgenetic
27708008
CUE3_YEASTCUE3genetic
27708008
AROC_YEASTARO2genetic
27708008
MED5_YEASTNUT1genetic
27708008
DSD1_YEASTDSD1genetic
27708008
HTD2_YEASTHTD2genetic
27708008
RPE_YEASTRPE1genetic
27708008
EI2BA_YEASTGCN3genetic
27708008
UTH1_YEASTUTH1genetic
27708008
YL149_YEASTYLR149Cgenetic
27708008
EFM7_YEASTNNT1genetic
27708008
NKP2_YEASTNKP2genetic
27708008
HXT2_YEASTHXT2genetic
27708008
DFG5_YEASTDFG5genetic
27708008
IDH1_YEASTIDH1genetic
27708008
OCA2_YEASTOCA2genetic
27708008
YNO0_YEASTYNL140Cgenetic
27708008
PHO80_YEASTPHO80genetic
27708008
KPR5_YEASTPRS5genetic
27708008
ADH1_YEASTADH1genetic
27708008
RMI1_YEASTRMI1genetic
27708008
ROX1_YEASTROX1genetic
27708008
UBA3_YEASTUBA3genetic
27708008
MED1_YEASTMED1genetic
27708008
TKT1_YEASTTKL1genetic
27708008
YP078_YEASTYPR078Cgenetic
27708008
COG3_YEASTCOG3genetic
29674565
YPT6_YEASTYPT6genetic
29674565
SCS7_YEASTSCS7genetic
29674565
KPC1_YEASTPKC1genetic
29674565
TRS20_YEASTTRS20genetic
29674565
VAM6_YEASTVAM6genetic
29674565
TRS23_YEASTTRS23genetic
29674565
FCF1_YEASTFCF1genetic
29674565
EMI1_YEASTEMI1genetic
29674565
CEM1_YEASTCEM1genetic
29674565
SEC4_YEASTSEC4genetic
29674565
HUR1_YEASTHUR1genetic
29674565
SKI8_YEASTSKI8genetic
29674565
NDT80_YEASTNDT80genetic
29674565
ARP1_YEASTARP1genetic
29674565
STB5_YEASTSTB5genetic
29674565
RIC1_YEASTRIC1genetic
29674565
SIC1_YEASTSIC1genetic
29674565
SKI2_YEASTSKI2genetic
29674565
NU188_YEASTNUP188genetic
29674565
CAP_YEASTSRV2genetic
29674565
ADE_YEASTAAH1genetic
29674565
PHO80_YEASTPHO80genetic
29674565
SFL1_YEASTSFL1genetic
29674565
HSP7F_YEASTSSE1genetic
29674565
KAR3_YEASTKAR3genetic
29674565
HDA3_YEASTHDA3genetic
29674565
SEC23_YEASTSEC23genetic
29674565
SKI3_YEASTSKI3genetic
29674565
SWC5_YEASTSWC5genetic
29674565
OCA5_YEASTOCA5genetic
29674565
ICE2_YEASTICE2genetic
29674565
MOG1_YEASTMOG1genetic
29674565
VRP1_YEASTVRP1genetic
29674565
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of OCA6_YEAST

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Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"A multidimensional chromatography technology for in-depthphosphoproteome analysis.";
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.;
Mol. Cell. Proteomics 7:1389-1396(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-2; SER-211 AND SER-215,AND MASS SPECTROMETRY.

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