OCA2_YEAST - dbPTM
OCA2_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID OCA2_YEAST
UniProt AC P53949
Protein Name Tyrosine-protein phosphatase-like protein OCA2
Gene Name OCA2
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 197
Subcellular Localization Cytoplasm .
Protein Description Required for normal growth in the presence of linoleic acid hydroperoxide (LoaOOH)..
Protein Sequence MKYIPPLNFSPVVSTDVSLYRSGYPMPLNYSFIKHQLHLKTIIYIGDKDRPLEEYQSFLESEKIKYYHIFMDSSRDEGIQERMNQVLHLVLDVRNYPILVHSNKGKHRVGVVVGIIRKLLQGWSTAGICQEYGLFSGGMKDGVDLEFITMFETNLKIPRNVIPGFAKHCLYLNELEAAEGSDDESGSESILTAKQPI
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
3Phosphorylation-----MKYIPPLNFS
-----CCCCCCCCCC		19.8428132839
181PhosphorylationELEAAEGSDDESGSE
HHHHHCCCCCCCCCC		33.1317330950
185PhosphorylationAEGSDDESGSESILT
HCCCCCCCCCCCCCE		55.3917330950
187PhosphorylationGSDDESGSESILTAK
CCCCCCCCCCCCEEC		37.1328889911
189PhosphorylationDDESGSESILTAKQP
CCCCCCCCCCEECCC		25.2919795423
192PhosphorylationSGSESILTAKQPI--
CCCCCCCEECCCC--		30.0919795423
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of OCA2_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of OCA2_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of OCA2_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
OCA1_YEASTOCA1physical
11805837
SIW14_YEASTSIW14physical
10688190
OCA1_YEASTOCA1physical
10688190
SIW14_YEASTSIW14physical
11283351
OCA1_YEASTOCA1physical
11283351
SIW14_YEASTSIW14physical
18719252
OCA1_YEASTOCA1physical
18719252
INP52_YEASTINP52genetic
19269370
XPOT_YEASTLOS1genetic
18408161
CIN1_YEASTCIN1genetic
18408161
CHK1_YEASTCHK1genetic
20093466
THRC_YEASTTHR4genetic
20093466
CSM1_YEASTCSM1genetic
20093466
VAM6_YEASTVAM6genetic
20093466
VPS41_YEASTVPS41genetic
20093466
ARO1_YEASTARO1genetic
20093466
VAM7_YEASTVAM7genetic
20093466
ATC1_YEASTPMR1genetic
20093466
MED5_YEASTNUT1genetic
20093466
CSK2B_YEASTCKB1genetic
20093466
RS25A_YEASTRPS25Agenetic
20093466
BNR1_YEASTBNR1genetic
20093466
MPH1_YEASTMPH1genetic
20093466
SNA3_YEASTSNA3genetic
20093466
DLS1_YEASTDLS1genetic
20093466
IME1_YEASTIME1genetic
20093466
MSN4_YEASTMSN4genetic
20093466
FABG_YEASTOAR1genetic
20093466
EST1_YEASTEST1genetic
20093466
RS30A_YEASTRPS30Agenetic
20093466
RS30B_YEASTRPS30Agenetic
20093466
NKP2_YEASTNKP2genetic
20093466
AIM34_YEASTAIM34genetic
20093466
SNO1_YEASTSNO1genetic
20093466
KU70_YEASTYKU70genetic
20093466
JNM1_YEASTJNM1genetic
20093466
KPR5_YEASTPRS5genetic
20093466
PHO80_YEASTPHO80genetic
20093466
VPS5_YEASTVPS5genetic
20093466
SKI7_YEASTSKI7genetic
20093466
SFL1_YEASTSFL1genetic
20093466
ISU2_YEASTISU2genetic
20093466
MKK1_YEASTMKK1genetic
20093466
SRL1_YEASTSRL1genetic
20093466
VPH1_YEASTVPH1genetic
20093466
DDC1_YEASTDDC1genetic
20093466
MRX11_YEASTYPL041Cgenetic
20093466
MED1_YEASTMED1genetic
20093466
TKT1_YEASTTKL1genetic
20093466
AGO1_SCHPOago1physical
20404084
PRW1_SCHPOprw1physical
20404084
HAT1_SCHPOhat1physical
20404084
CHA4_YEASTCHA4physical
20404084
CLR6_SCHPOclr6genetic
20404084
OCA5_YEASTOCA5genetic
19176519
GCN2_YEASTGCN2genetic
19176519
SIW14_YEASTSIW14genetic
21409566
VIP1_YEASTVIP1genetic
21127252
CBF1_YEASTCBF1genetic
21127252
IXR1_YEASTIXR1genetic
21127252
VAC14_YEASTVAC14genetic
21127252
AFT1_YEASTAFT1genetic
21127252
UME6_YEASTUME6genetic
21127252
CHK1_YEASTCHK1genetic
22282571
SKI2_YEASTSKI2genetic
26344770
CND2_YEASTBRN1genetic
27708008
RPN12_YEASTRPN12genetic
27708008
SWC4_YEASTSWC4genetic
27708008
RRP4_YEASTRRP4genetic
27708008
TAD3_YEASTTAD3genetic
27708008
RUD3_YEASTRUD3genetic
27708008
YP107_YEASTYPL107Wgenetic
27708008
STU1_YEASTSTU1genetic
27708008
CDC27_YEASTCDC27genetic
27708008
KPC1_YEASTPKC1genetic
27708008
TAF5_YEASTTAF5genetic
27708008
MPS1_YEASTMPS1genetic
27708008
SUB2_YEASTSUB2genetic
27708008
DPOD_YEASTPOL3genetic
27708008
UAP1_YEASTQRI1genetic
27708008
NSE4_YEASTNSE4genetic
27708008
CDC13_YEASTCDC13genetic
27708008
CDC37_YEASTCDC37genetic
27708008
CDC1_YEASTCDC1genetic
27708008
TCPA_YEASTTCP1genetic
27708008
GPI19_YEASTGPI19genetic
27708008
SEC4_YEASTSEC4genetic
27708008
SMC1_YEASTSMC1genetic
27708008
CAK1_YEASTCAK1genetic
27708008
ACT_YEASTACT1genetic
27708008
RPN11_YEASTRPN11genetic
27708008
PRS8_YEASTRPT6genetic
27708008
TIP20_YEASTTIP20genetic
27708008
SPT16_YEASTSPT16genetic
27708008
SYYC_YEASTTYS1genetic
27708008
TAF1_YEASTTAF1genetic
27708008
BRL1_YEASTBRL1genetic
27708008
DNA2_YEASTDNA2genetic
27708008
RPC9_YEASTRPC17genetic
27708008
GRP78_YEASTKAR2genetic
27708008
CDC6_YEASTCDC6genetic
27708008
DPOD2_YEASTPOL31genetic
27708008
KTHY_YEASTCDC8genetic
27708008
CDC11_YEASTCDC11genetic
27708008
PRS7_YEASTRPT1genetic
27708008
YKT6_YEASTYKT6genetic
27708008
CDC42_YEASTCDC42genetic
27708008
STT4_YEASTSTT4genetic
27708008
SEN1_YEASTSEN1genetic
27708008
CDC91_YEASTGAB1genetic
27708008
TAF4_YEASTTAF4genetic
27708008
RFC4_YEASTRFC4genetic
27708008
MED4_YEASTMED4genetic
27708008
GPI2_YEASTGPI2genetic
27708008
MOT1_YEASTMOT1genetic
27708008
IPL1_YEASTIPL1genetic
27708008
SYH_YEASTHTS1genetic
27708008
PSB5_YEASTPRE2genetic
27708008
MED10_YEASTNUT2genetic
27708008
ETR1_YEASTETR1genetic
27708008
THRC_YEASTTHR4genetic
27708008
CSM1_YEASTCSM1genetic
27708008
VAM6_YEASTVAM6genetic
27708008
VMS1_YEASTVMS1genetic
27708008
ARO1_YEASTARO1genetic
27708008
ATC1_YEASTPMR1genetic
27708008
MPH1_YEASTMPH1genetic
27708008
SDHX_YEASTYJL045Wgenetic
27708008
DLS1_YEASTDLS1genetic
27708008
IME1_YEASTIME1genetic
27708008
AIM26_YEASTAIM26genetic
27708008
RS30A_YEASTRPS30Agenetic
27708008
RS30B_YEASTRPS30Agenetic
27708008
AIM34_YEASTAIM34genetic
27708008
PHO80_YEASTPHO80genetic
27708008
MGR2_YEASTMGR2genetic
27708008
TBCC_YEASTCIN2genetic
27708008
UBA3_YEASTUBA3genetic
27708008
TKT1_YEASTTKL1genetic
27708008
EVI5L_HUMANEVI5Lphysical
27107014
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of OCA2_YEAST

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Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"A multidimensional chromatography technology for in-depthphosphoproteome analysis.";
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.;
Mol. Cell. Proteomics 7:1389-1396(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-181, AND MASSSPECTROMETRY.
"Large-scale phosphorylation analysis of alpha-factor-arrestedSaccharomyces cerevisiae.";
Li X., Gerber S.A., Rudner A.D., Beausoleil S.A., Haas W., Villen J.,Elias J.E., Gygi S.P.;
J. Proteome Res. 6:1190-1197(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-181, AND MASSSPECTROMETRY.

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