| UniProt ID | BRL1_YEAST | |
|---|---|---|
| UniProt AC | P38770 | |
| Protein Name | Nucleus export protein BRL1 | |
| Gene Name | BRL1 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 471 | |
| Subcellular Localization |
Nucleus membrane Multi-pass membrane protein . |
|
| Protein Description | Involved in mRNA and protein export from nucleus.. | |
| Protein Sequence | MESFENLSIRDSFTSGMEHVDEELGGLSDLSISKQGPTLSPQLINRFMPHFPSSPSPLRNTLDFSAAKADEEEDDRMEIDEVDDTSFEEEYNNEPIETHTEATENAVVEEIEATPEERQKQEKNESQDQSVEEVENIVSPHRSTVIKALLSPTDLGVAAATKVEGVVPLPPSANQDDNESSNNNAEGEDIIRNEEVEDEIKSSLGNHKSSQYANAFDSEIIKRELRSRSKYQPIQVSFNTHNYFYSDKDGIKTYSLTKPNHNKIDEFYDQNEAFKLPKPWSPNSHPASRASYALMSYLQLFLNAITTVVIFSFILSFIIALQKDLKSTWEQRKHELQYESRICQEQYLTNRCNQTPGLPALGEQCAIWKQCMDRNNDIFFRARSTLSAKLFGDIINSFIDPLNWKTLFVIFCGVITWCFSSNFLLGFVRAKSYYGNGIKTYPLPSSPKSPTSEETHSSMTASGEDSHLLKQ | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 3 | Phosphorylation | -----MESFENLSIR -----CCCCCCCCHH | 36.24 | 30377154 | |
| 12 | Phosphorylation | ENLSIRDSFTSGMEH CCCCHHHCCCCCCCH | 22.15 | 30377154 | |
| 15 | Phosphorylation | SIRDSFTSGMEHVDE CHHHCCCCCCCHHHH | 33.85 | 30377154 | |
| 28 | Phosphorylation | DEELGGLSDLSISKQ HHHHCCCCCCCCCCC | 39.52 | 30377154 | |
| 31 | Phosphorylation | LGGLSDLSISKQGPT HCCCCCCCCCCCCCC | 29.79 | 30377154 | |
| 38 | Phosphorylation | SISKQGPTLSPQLIN CCCCCCCCCCHHHHH | 46.85 | 29688323 | |
| 40 | Phosphorylation | SKQGPTLSPQLINRF CCCCCCCCHHHHHHH | 17.06 | 24909858 | |
| 53 | Phosphorylation | RFMPHFPSSPSPLRN HHCCCCCCCCCCCCC | 54.67 | 28889911 | |
| 54 | Phosphorylation | FMPHFPSSPSPLRNT HCCCCCCCCCCCCCC | 29.63 | 28889911 | |
| 56 | Phosphorylation | PHFPSSPSPLRNTLD CCCCCCCCCCCCCCC | 38.22 | 28889911 | |
| 126 | Phosphorylation | QKQEKNESQDQSVEE HHHHHCCCCCCCHHH | 48.74 | 29688323 | |
| 130 | Phosphorylation | KNESQDQSVEEVENI HCCCCCCCHHHHHHH | 39.52 | 21440633 | |
| 139 | Phosphorylation | EEVENIVSPHRSTVI HHHHHHHCCCHHHHH | 15.93 | 23749301 | |
| 143 | Phosphorylation | NIVSPHRSTVIKALL HHHCCCHHHHHHHHC | 24.80 | 21440633 | |
| 151 | Phosphorylation | TVIKALLSPTDLGVA HHHHHHCCCCCCCCH | 26.97 | 21551504 | |
| 445 | Phosphorylation | IKTYPLPSSPKSPTS CEEEECCCCCCCCCC | 67.94 | 28889911 | |
| 446 | Phosphorylation | KTYPLPSSPKSPTSE EEEECCCCCCCCCCC | 34.11 | 21440633 | |
| 452 | Phosphorylation | SSPKSPTSEETHSSM CCCCCCCCCCCCCCC | 36.50 | 21551504 | |
| 455 | Phosphorylation | KSPTSEETHSSMTAS CCCCCCCCCCCCCCC | 24.01 | 21440633 | |
| 462 | Phosphorylation | THSSMTASGEDSHLL CCCCCCCCCCCCHHC | 33.28 | 21551504 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of BRL1_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of BRL1_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of BRL1_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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