dbPTM

DCI1_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	DCI1_YEAST
UniProt AC	Q08558
Protein Name	Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase
Gene Name	DCI1
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	271
Subcellular Localization	Peroxisome .
Protein Description	Converts 3,5-dienoyl-CoAs to the corresponding 2,4-dienoyl-CoAs. Involved in fatty acid metabolism. Required for ECI1 to be peroxisomal located..
Protein Sequence	MSSRVCYHINGPFFIIKLIDPKHLNSLTFEDFVYIALLLHKANDIDSVLFTVLQSSGKYFSSGGKFSAVNKLNDGDVTSEVEKVSKLVSAISSPNIFVANAFAIHKKVLVCCLNGPAIGLSASLVALCDIVYSQNDSVFLLFPFSNLGFVAEVGTSVTLTQKLGINSANEHMIFSTPVLFKELIGTIITKNYQLTNTETFNEKVLQDIKQNLEGLYPKSVLGMKELLHSEMKQKLIKAQAMETNGTLPFWASGEPFKRFKQLQEGNRRHKL

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
260	Ubiquitination	GEPFKRFKQLQEGNR CCCCHHHHHHHHCCC	54.88	24961812

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of DCI1_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of DCI1_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of DCI1_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ECI1_YEAST	ECI1	physical	10688190
ECI1_YEAST	ECI1	physical	10381339
PEX14_YEAST	PEX14	physical	11283351
AATC_YEAST	AAT2	genetic	21623372
IDH1_YEAST	IDH1	genetic	21623372
PFKA1_YEAST	PFK1	genetic	21623372
AROC_YEAST	ARO2	genetic	21623372
ARO1_YEAST	ARO1	genetic	21623372
KCS1_YEAST	KCS1	genetic	21623372
THDH_YEAST	ILV1	genetic	21623372
PSD2_YEAST	PSD2	genetic	21623372
SCS7_YEAST	SCS7	genetic	21623372
YCY0_YEAST	YCR090C	genetic	27708008
YL287_YEAST	YLR287C	genetic	27708008
ATC3_YEAST	DRS2	genetic	27708008
YAJ9_YEAST	YAR029W	genetic	27708008
RL19A_YEAST	RPL19B	genetic	27708008
RL19B_YEAST	RPL19B	genetic	27708008
URA7_YEAST	URA7	genetic	27708008
RTG3_YEAST	RTG3	genetic	27708008
PER1_YEAST	PER1	genetic	27708008
CSM1_YEAST	CSM1	genetic	27708008
VAM6_YEAST	VAM6	genetic	27708008
PUF6_YEAST	PUF6	genetic	27708008
EDC1_YEAST	EDC1	genetic	27708008
ASK10_YEAST	ASK10	genetic	27708008
GOSR1_YEAST	GOS1	genetic	27708008
AGE2_YEAST	AGE2	genetic	27708008
YIG7_YEAST	YIL067C	genetic	27708008
PIR5_YEAST	YJL160C	genetic	27708008
ELM1_YEAST	ELM1	genetic	27708008
RL22A_YEAST	RPL22A	genetic	27708008
CCW12_YEAST	CCW12	genetic	27708008
YL224_YEAST	YLR224W	genetic	27708008
TDA5_YEAST	TDA5	genetic	27708008
YM39_YEAST	YMR166C	genetic	27708008

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of DCI1_YEAST

Related Literatures of Post-Translational Modification