| UniProt ID | AROC_YEAST | |
|---|---|---|
| UniProt AC | P28777 | |
| Protein Name | Chorismate synthase | |
| Gene Name | ARO2 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 376 | |
| Subcellular Localization | ||
| Protein Description | ||
| Protein Sequence | MSTFGKLFRVTTYGESHCKSVGCIVDGVPPGMSLTEADIQPQLTRRRPGQSKLSTPRDEKDRVEIQSGTEFGKTLGTPIAMMIKNEDQRPHDYSDMDKFPRPSHADFTYSEKYGIKASSGGGRASARETIGRVASGAIAEKFLAQNSNVEIVAFVTQIGEIKMNRDSFDPEFQHLLNTITREKVDSMGPIRCPDASVAGLMVKEIEKYRGNKDSIGGVVTCVVRNLPTGLGEPCFDKLEAMLAHAMLSIPASKGFEIGSGFQGVSVPGSKHNDPFYFEKETNRLRTKTNNSGGVQGGISNGENIYFSVPFKSVATISQEQKTATYDGEEGILAAKGRHDPAVTPRAIPIVEAMTALVLADALLIQKARDFSRSVVH | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 2 | Acetylation | ------MSTFGKLFR ------CCCCCCCEE | 32.23 | 22814378 | |
| 6 | Acetylation | --MSTFGKLFRVTTY --CCCCCCCEEEEEC | 40.02 | 24489116 | |
| 11 | Phosphorylation | FGKLFRVTTYGESHC CCCCEEEEECCHHHC | 15.28 | 21551504 | |
| 12 | Phosphorylation | GKLFRVTTYGESHCK CCCEEEEECCHHHCE | 27.03 | 20377248 | |
| 13 | Phosphorylation | KLFRVTTYGESHCKS CCEEEEECCHHHCEE | 14.99 | 21440633 | |
| 16 | Phosphorylation | RVTTYGESHCKSVGC EEEECCHHHCEECCE | 29.80 | 20377248 | |
| 20 | Phosphorylation | YGESHCKSVGCIVDG CCHHHCEECCEEECC | 29.18 | 27017623 | |
| 35 | Phosphorylation | VPPGMSLTEADIQPQ CCCCCCCCHHHCCHH | 23.09 | 28889911 | |
| 55 | Phosphorylation | PGQSKLSTPRDEKDR CCCCCCCCCCCHHHC | 32.55 | 28889911 | |
| 60 | Acetylation | LSTPRDEKDRVEIQS CCCCCCHHHCEEECC | 55.94 | 24489116 | |
| 67 | Phosphorylation | KDRVEIQSGTEFGKT HHCEEECCCCHHHHC | 54.03 | 22369663 | |
| 69 | Phosphorylation | RVEIQSGTEFGKTLG CEEECCCCHHHHCCC | 33.13 | 22369663 | |
| 74 | Phosphorylation | SGTEFGKTLGTPIAM CCCHHHHCCCCCEEE | 30.69 | 22369663 | |
| 77 | Phosphorylation | EFGKTLGTPIAMMIK HHHHCCCCCEEEEEE | 18.03 | 22369663 | |
| 98 | Acetylation | HDYSDMDKFPRPSHA CCCCCCCCCCCCCCC | 51.10 | 24489116 | |
| 112 | Acetylation | ADFTYSEKYGIKASS CCCCCCHHHCCEECC | 42.72 | 24489116 | |
| 118 | Phosphorylation | EKYGIKASSGGGRAS HHHCCEECCCCCCCC | 25.23 | 27017623 | |
| 119 | Phosphorylation | KYGIKASSGGGRASA HHCCEECCCCCCCCH | 46.44 | 27017623 | |
| 167 | Phosphorylation | EIKMNRDSFDPEFQH EEECCCCCCCHHHHH | 28.45 | 24961812 | |
| 203 | Acetylation | SVAGLMVKEIEKYRG HHHHEEHHHHHHHCC | 38.72 | 24489116 | |
| 212 | Acetylation | IEKYRGNKDSIGGVV HHHHCCCCCCCCCEE | 56.53 | 24489116 | |
| 248 | Phosphorylation | MLAHAMLSIPASKGF HHHHHHHCCCHHCCC | 17.28 | 22369663 | |
| 252 | Phosphorylation | AMLSIPASKGFEIGS HHHCCCHHCCCCCCC | 28.14 | 22369663 | |
| 259 | Phosphorylation | SKGFEIGSGFQGVSV HCCCCCCCCCCCEEC | 41.94 | 21440633 | |
| 270 | Acetylation | GVSVPGSKHNDPFYF CEECCCCCCCCCCCE | 52.95 | 24489116 | |
| 279 | Acetylation | NDPFYFEKETNRLRT CCCCCEECCCCCCEE | 61.00 | 24489116 | |
| 321 | Ubiquitination | ATISQEQKTATYDGE EEECCEEEEEEECCC | 39.10 | 23749301 | |
| 321 | Acetylation | ATISQEQKTATYDGE EEECCEEEEEEECCC | 39.10 | 24489116 | |
| 322 | Phosphorylation | TISQEQKTATYDGEE EECCEEEEEEECCCC | 24.75 | 21126336 | |
| 324 | Phosphorylation | SQEQKTATYDGEEGI CCEEEEEEECCCCCE | 27.63 | 27214570 | |
| 335 | Acetylation | EEGILAAKGRHDPAV CCCEEEECCCCCCCC | 51.36 | 24489116 | |
| 335 | Ubiquitination | EEGILAAKGRHDPAV CCCEEEECCCCCCCC | 51.36 | 23749301 | |
| 335 | Succinylation | EEGILAAKGRHDPAV CCCEEEECCCCCCCC | 51.36 | 23954790 | |
| 343 | Phosphorylation | GRHDPAVTPRAIPIV CCCCCCCCCCHHHHH | 14.79 | 28889911 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of AROC_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of AROC_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of AROC_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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| Phosphorylation | |
| Reference | PubMed |
| "A multidimensional chromatography technology for in-depthphosphoproteome analysis."; Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.; Mol. Cell. Proteomics 7:1389-1396(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-55 AND THR-324, AND MASSSPECTROMETRY. | |
