| UniProt ID | MVD1_YEAST | |
|---|---|---|
| UniProt AC | P32377 | |
| Protein Name | Diphosphomevalonate decarboxylase | |
| Gene Name | MVD1 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 396 | |
| Subcellular Localization | ||
| Protein Description | ||
| Protein Sequence | MTVYTASVTAPVNIATLKYWGKRDTKLNLPTNSSISVTLSQDDLRTLTSAATAPEFERDTLWLNGEPHSIDNERTQNCLRDLRQLRKEMESKDASLPTLSQWKLHIVSENNFPTAAGLASSAAGFAALVSAIAKLYQLPQSTSEISRIARKGSGSACRSLFGGYVAWEMGKAEDGHDSMAVQIADSSDWPQMKACVLVVSDIKKDVSSTQGMQLTVATSELFKERIEHVVPKRFEVMRKAIVEKDFATFAKETMMDSNSFHATCLDSFPPIFYMNDTSKRIISWCHTINQFYGETIVAYTFDAGPNAVLYYLAENESKLFAFIYKLFGSVPGWDKKFTTEQLEAFNHQFESSNFTARELDLELQKDVARVILTQVGSGPQETNESLIDAKTGLPKE | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 2 | Phosphorylation | ------MTVYTASVT ------CCEEEEEEE | 23.40 | 28889911 | |
| 92 | Acetylation | LRKEMESKDASLPTL HHHHHHHCCCCCCCH | 43.96 | 24489116 | |
| 200 | Phosphorylation | KACVLVVSDIKKDVS CCEEEEEECHHHCCC | 26.58 | 22369663 | |
| 244 | 2-Hydroxyisobutyrylation | MRKAIVEKDFATFAK HHHHHHHHHHHHHHH | 47.45 | - | |
| 244 | Succinylation | MRKAIVEKDFATFAK HHHHHHHHHHHHHHH | 47.45 | 23954790 | |
| 253 | Phosphorylation | FATFAKETMMDSNSF HHHHHHHHHCCCCCE | 19.65 | 27017623 | |
| 339 | Phosphorylation | GWDKKFTTEQLEAFN CCCCCCCHHHHHHHC | 25.52 | 21440633 | |
| 351 | Phosphorylation | AFNHQFESSNFTARE HHCHHHHHCCCCHHH | 31.69 | 21440633 | |
| 385 | Phosphorylation | GPQETNESLIDAKTG CCCCCCHHHCHHCCC | 32.47 | 28152593 | |
| 390 | Acetylation | NESLIDAKTGLPKE- CHHHCHHCCCCCCC- | 39.10 | 24489116 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of MVD1_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of MVD1_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of MVD1_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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| Phosphorylation | |
| Reference | PubMed |
| "A multidimensional chromatography technology for in-depthphosphoproteome analysis."; Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.; Mol. Cell. Proteomics 7:1389-1396(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-2, AND MASSSPECTROMETRY. | |
