TRPG_YEAST - dbPTM
TRPG_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID TRPG_YEAST
UniProt AC P00937
Protein Name Multifunctional tryptophan biosynthesis protein
Gene Name TRP3
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 484
Subcellular Localization
Protein Description
Protein Sequence MSVHAATNPINKHVVLIDNYDSFTWNVYEYLCQEGAKVSVYRNDAITVPEIAALNPDTLLISPGPGHPKTDSGISRDCIRYFTGKIPVFGICMGQQCMFDVFGGEVAYAGEIVHGKTSPISHDNCGIFKNVPQGIAVTRYHSLAGTESSLPSCLKVTASTENGIIMGVRHKKYTVEGVQFHPESILTEEGHLMIRNILNVSGGTWEENKSSPSNSILDRIYARRKIDVNEQSKIPGFTFQDLQSNYDLGLAPPLQDFYTVLSSSHKRAVVLAEVKRASPSKGPICLKAVAAEQALKYAEAGASAISVLTEPHWFHGSLQDLVNVRKILDLKFPPKERPCVLRKEFIFSKYQILEARLAGADTVLLIVKMLSQPLLKELYSYSKDLNMEPLVEVNSKEELQRALEIGAKVVGVNNRDLHSFNVDLNTTSNLVESIPKDVLLIALSGITTRDDAEKYKKEGVHGFLVGEALMKSTDVKKFIHELCE
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
2Phosphorylation------MSVHAATNP
------CCCCCCCCC		23.7022369663
7Phosphorylation-MSVHAATNPINKHV
-CCCCCCCCCCCCCE		42.1622369663
117PhosphorylationGEIVHGKTSPISHDN
CEEECCCCCCCCCCC		44.3129136822
118PhosphorylationEIVHGKTSPISHDNC
EEECCCCCCCCCCCC		24.5829136822
121PhosphorylationHGKTSPISHDNCGIF
CCCCCCCCCCCCCCC		28.3329136822
129AcetylationHDNCGIFKNVPQGIA
CCCCCCCCCCCCCEE		55.9322865919
204PhosphorylationILNVSGGTWEENKSS
EEECCCCCCCCCCCC		32.9822369663
210PhosphorylationGTWEENKSSPSNSIL
CCCCCCCCCCCCHHH		60.0922369663
211PhosphorylationTWEENKSSPSNSILD
CCCCCCCCCCCHHHH		33.6822369663
213PhosphorylationEENKSSPSNSILDRI
CCCCCCCCCHHHHHH		45.1922369663
215PhosphorylationNKSSPSNSILDRIYA
CCCCCCCHHHHHHHH		28.9422369663
287AcetylationSKGPICLKAVAAEQA
CCCCCHHHHHHHHHH		36.0822865919
343AcetylationERPCVLRKEFIFSKY
CCCCEECCHHCCCHH		53.4622865919
376AcetylationMLSQPLLKELYSYSK
HHCHHHHHHHHHHCC		54.0524489116
380PhosphorylationPLLKELYSYSKDLNM
HHHHHHHHHCCCCCC		35.2419779198
381PhosphorylationLLKELYSYSKDLNME
HHHHHHHHCCCCCCC		13.2419779198
395PhosphorylationEPLVEVNSKEELQRA
CCCEECCCHHHHHHH		46.7719779198
444PhosphorylationDVLLIALSGITTRDD
HHHHHHHCCCCCHHH		21.0828889911
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of TRPG_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of TRPG_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of TRPG_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
AHA1_YEASTAHA1physical
16429126
ARO1_YEASTARO1physical
16429126
HSC82_YEASTHSC82physical
16429126
RPA2_YEASTRPA135physical
16429126
PRS6B_YEASTRPT3physical
16429126
METK1_YEASTSAM1physical
16429126
TRPE_YEASTTRP2physical
16429126
TBA3_YEASTTUB3physical
16429126
GFA1_YEASTGFA1physical
16429126
TRPE_YEASTTRP2physical
18719252
SMT3_YEASTSMT3physical
18719252
EKI1_YEASTEKI1genetic
20093466
MSH4_YEASTMSH4genetic
20093466
YJ24_YEASTKCH1genetic
20093466
ERG6_YEASTERG6genetic
20093466
RIM13_YEASTRIM13genetic
20093466
MSB4_YEASTMSB4genetic
20093466
TAT2_YEASTTAT2genetic
20093466
SDHX_YEASTYJL045Wgenetic
21623372
ERG6_YEASTERG6genetic
21623372
FABD_YEASTMCT1genetic
21623372
CYS3_YEASTCYS3genetic
21623372
DAL4_YEASTDAL4genetic
21623372
ETR1_YEASTETR1genetic
21623372
CY1_YEASTCYT1genetic
21623372
THRC_YEASTTHR4genetic
21623372
CHO2_YEASTCHO2genetic
21623372
COQ7_YEASTCAT5genetic
21623372
DHAS_YEASTHOM2genetic
21623372
PDX3_YEASTPDX3genetic
21623372
RXT3_YEASTRXT3genetic
27708008
MNN10_YEASTMNN10genetic
27708008
MSH4_YEASTMSH4genetic
27708008
MRM2_YEASTMRM2genetic
27708008
SNF6_YEASTSNF6genetic
27708008
YJ24_YEASTKCH1genetic
27708008
ITPA_YEASTHAM1genetic
27708008
RL8B_YEASTRPL8Bgenetic
27708008
ERG6_YEASTERG6genetic
27708008
TMA23_YEASTTMA23genetic
27708008
TAT2_YEASTTAT2genetic
27708008
MSB4_YEASTMSB4genetic
27708008
LPX1_YEASTLPX1genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of TRPG_YEAST

loading...

Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"A multidimensional chromatography technology for in-depthphosphoproteome analysis.";
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.;
Mol. Cell. Proteomics 7:1389-1396(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-2; SER-211 AND SER-444,AND MASS SPECTROMETRY.

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory