| UniProt ID | PDX3_YEAST | |
|---|---|---|
| UniProt AC | P38075 | |
| Protein Name | Pyridoxamine 5'-phosphate oxidase | |
| Gene Name | PDX3 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 228 | |
| Subcellular Localization | Mitochondrion intermembrane space . | |
| Protein Description | Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).. | |
| Protein Sequence | MTKQAEETQKPIIFAPETYQYDKFTLNEKQLTDDPIDLFTKWFNEAKEDPRETLPEAITFSSAELPSGRVSSRILLFKELDHRGFTIYSNWGTSRKAHDIATNPNAAIVFFWKDLQRQVRVEGITEHVNRETSERYFKTRPRGSKIGAWASRQSDVIKNREELDELTQKNTERFKDAEDIPCPDYWGGLRIVPLEIEFWQGRPSRLHDRFVYRRKTENDPWKVVRLAP | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
|
|
||
* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 10 | Acetylation | KQAEETQKPIIFAPE CCCHHHCCCEEECCC | 45.67 | 24489116 | |
| 18 | Phosphorylation | PIIFAPETYQYDKFT CEEECCCCCCCCCCC | 18.18 | 22369663 | |
| 19 | Phosphorylation | IIFAPETYQYDKFTL EEECCCCCCCCCCCC | 11.92 | 22369663 | |
| 21 | Phosphorylation | FAPETYQYDKFTLNE ECCCCCCCCCCCCCH | 15.64 | 22369663 | |
| 25 | Phosphorylation | TYQYDKFTLNEKQLT CCCCCCCCCCHHHCC | 34.12 | 22369663 | |
| 29 | Ubiquitination | DKFTLNEKQLTDDPI CCCCCCHHHCCCCHH | 49.92 | 24961812 | |
| 29 | Acetylation | DKFTLNEKQLTDDPI CCCCCCHHHCCCCHH | 49.92 | 24489116 | |
| 67 | Phosphorylation | FSSAELPSGRVSSRI CCCCCCCCCCCCCEE | 52.43 | 26447709 | |
| 71 | Phosphorylation | ELPSGRVSSRILLFK CCCCCCCCCEEEEEE | 16.73 | 26447709 | |
| 72 | Phosphorylation | LPSGRVSSRILLFKE CCCCCCCCEEEEEEE | 22.08 | 26447709 | |
| 78 | Acetylation | SSRILLFKELDHRGF CCEEEEEEECCCCCE | 58.29 | 24489116 | |
| 86 | Phosphorylation | ELDHRGFTIYSNWGT ECCCCCEEEECCCCC | 23.10 | 28889911 | |
| 88 | Phosphorylation | DHRGFTIYSNWGTSR CCCCEEEECCCCCCC | 7.90 | 28889911 | |
| 94 | Phosphorylation | IYSNWGTSRKAHDIA EECCCCCCCCHHHHC | 28.04 | 28889911 | |
| 151 | Phosphorylation | SKIGAWASRQSDVIK CCCCHHHHCCCHHCC | 21.83 | 22369663 | |
| 154 | Phosphorylation | GAWASRQSDVIKNRE CHHHHCCCHHCCCHH | 32.51 | 22369663 | |
| 158 | Acetylation | SRQSDVIKNREELDE HCCCHHCCCHHHHHH | 50.21 | 24489116 | |
| 169 | Acetylation | ELDELTQKNTERFKD HHHHHHHHHHHHHCC | 61.68 | 24489116 | |
| 175 | Acetylation | QKNTERFKDAEDIPC HHHHHHHCCCCCCCC | 63.35 | 24489116 | |
| 204 | Phosphorylation | EFWQGRPSRLHDRFV EEECCCCCCCCCEEE | 46.22 | 22369663 | |
| 222 | Acetylation | KTENDPWKVVRLAP- CCCCCCCCEEEECC- | 35.92 | 24489116 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of PDX3_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of PDX3_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of PDX3_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
loading...
| Ubiquitylation | |
| Reference | PubMed |
| "A proteomics approach to understanding protein ubiquitination."; Peng J., Schwartz D., Elias J.E., Thoreen C.C., Cheng D.,Marsischky G., Roelofs J., Finley D., Gygi S.P.; Nat. Biotechnol. 21:921-926(2003). Cited for: UBIQUITINATION [LARGE SCALE ANALYSIS] AT LYS-29, AND MASSSPECTROMETRY. | |
