MRX8_YEAST - dbPTM
MRX8_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID MRX8_YEAST
UniProt AC Q05473
Protein Name MIOREX complex component 8 {ECO:0000305|PubMed:25683707}
Gene Name MRX8 {ECO:0000303|PubMed:25683707}
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 314
Subcellular Localization Mitochondrion .
Protein Description Component of MIOREX complexes, large expressome-like assemblies of ribosomes with factors involved in all the steps of post-transcriptional gene expression..
Protein Sequence MEQLCKRYVHTPAAFIQNIVANTKRTTLATQLSVEKAKKKVPKTALKKKLNSRPKERLPNWLKLNDVFNIHYEKPSNSDINKVNRFFNKAKVEFEWCAASFDDIPENPFLNKKSHKDILKDHGECGTTLIDTLPEVIFLGGTNVGKSSILNNITTSHVSRDLGSLARVSKTTGFTKTLNCYNVGNRLRMIDSPGYGFNSSKEQGKVTLQYLLERKQLVRCFLLLAGDKEINNTDNMIIQYIHEHGVPFEVVFTKMDKVKDLNKFKKKVMSSGLMDLPTLPRLVLTNSLTSSTSPKRFGIDLLRYVIFQSCGLIL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
192PhosphorylationNRLRMIDSPGYGFNS
CEEEEECCCCCCCCC
29734811
195PhosphorylationRMIDSPGYGFNSSKE
EEECCCCCCCCCCCC
29734811
271PhosphorylationFKKKVMSSGLMDLPT
HHHHHHHCCCCCCCC
25521595
278PhosphorylationSGLMDLPTLPRLVLT
CCCCCCCCCCEEEEC
25521595

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of MRX8_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of MRX8_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of MRX8_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
PET20_YEASTPET20genetic
27708008
CALM_YEASTCMD1genetic
27708008
RPAB1_YEASTRPB5genetic
27708008
PDC2_YEASTPDC2genetic
27708008
MOB2_YEASTMOB2genetic
27708008
CDC12_YEASTCDC12genetic
27708008
SEN1_YEASTSEN1genetic
27708008
MED11_YEASTMED11genetic
27708008
LST8_YEASTLST8genetic
27708008
TYSY_YEASTCDC21genetic
27708008
SNF5_YEASTSNF5genetic
27708008
SNF6_YEASTSNF6genetic
27708008
SDS3_YEASTSDS3genetic
27708008
PTK2_YEASTPTK2genetic
27708008
IXR1_YEASTIXR1genetic
27708008
RM39_YEASTMRPL39genetic
27708008
SAP30_YEASTSAP30genetic
27708008
PHO23_YEASTPHO23genetic
27708008
LSM7_YEASTLSM7genetic
27708008
SIN3_YEASTSIN3genetic
27708008
DNLI4_YEASTDNL4genetic
27708008
WHI5_YEASTWHI5genetic
27708008

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of MRX8_YEAST

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Related Literatures of Post-Translational Modification

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