PRM3_YEAST - dbPTM
PRM3_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID PRM3_YEAST
UniProt AC Q08931
Protein Name Pheromone-regulated membrane protein 3
Gene Name PRM3
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 133
Subcellular Localization Nucleus outer membrane
Single-pass membrane protein
Cytoplasmic side. Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body.
Protein Description Required for the fusion of nuclear envelopes during mating, ensuring proper karyogamy. Plays a role in the initiation of outer nuclear envelope fusion..
Protein Sequence MTAMKEDNAALITLKKNNDQEKLRVHKLTDASSNSADGFVINKAKNGGPLNKKSLVNNEQHIKKAVSPGRVRKHKTTTSSTKSRTKSKKKDASESKVQRENKGSFYQGAIFGSFLGAAVTTVLSNLAVKALQN
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
13PhosphorylationEDNAALITLKKNNDQ
CCCEEEEEEEECCHH
33.1227017623
67PhosphorylationQHIKKAVSPGRVRKH
HHHHHHCCCCCCCCC
26.8824930733
76PhosphorylationGRVRKHKTTTSSTKS
CCCCCCCCCCCCCCC
34.7228889911
77PhosphorylationRVRKHKTTTSSTKSR
CCCCCCCCCCCCCCC
29.5028889911
78PhosphorylationVRKHKTTTSSTKSRT
CCCCCCCCCCCCCCC
26.3828889911
79PhosphorylationRKHKTTTSSTKSRTK
CCCCCCCCCCCCCCC
33.6428889911
80PhosphorylationKHKTTTSSTKSRTKS
CCCCCCCCCCCCCCC
37.4528889911
81PhosphorylationHKTTTSSTKSRTKSK
CCCCCCCCCCCCCCC
32.5728889911
83PhosphorylationTTTSSTKSRTKSKKK
CCCCCCCCCCCCCCC
45.3228889911

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of PRM3_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of PRM3_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of PRM3_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
PRM3_YEASTPRM3physical
10688190
KAR5_YEASTKAR5physical
19297527
RV167_YEASTRVS167genetic
20093466
TPA1_YEASTTPA1genetic
20093466
YGY5_YEASTYGL235Wgenetic
20093466
PLMT_YEASTOPI3genetic
20093466
CYT2_YEASTCYT2genetic
20093466
RS3A1_YEASTRPS1Agenetic
20093466
KAR5_YEASTKAR5genetic
20093466
RAD1_YEASTRAD1genetic
20093466
MED1_YEASTMED1genetic
20093466
NPL4_YEASTNPL4genetic
27708008
REI1_YEASTREI1genetic
27708008
RV161_YEASTRVS161genetic
27708008
RV167_YEASTRVS167genetic
27708008
YGY5_YEASTYGL235Wgenetic
27708008
QCR9_YEASTQCR9genetic
27708008
CYT2_YEASTCYT2genetic
27708008
RSSA2_YEASTRPS0Bgenetic
27708008
SIC1_YEASTSIC1genetic
27708008
MMS22_YEASTMMS22genetic
27708008
KAR5_YEASTKAR5genetic
27708008
YOR31_YEASTYOR131Cgenetic
27708008

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of PRM3_YEAST

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Related Literatures of Post-Translational Modification

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