| UniProt ID | PRM3_YEAST | |
|---|---|---|
| UniProt AC | Q08931 | |
| Protein Name | Pheromone-regulated membrane protein 3 | |
| Gene Name | PRM3 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 133 | |
| Subcellular Localization |
Nucleus outer membrane Single-pass membrane protein Cytoplasmic side. Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body. |
|
| Protein Description | Required for the fusion of nuclear envelopes during mating, ensuring proper karyogamy. Plays a role in the initiation of outer nuclear envelope fusion.. | |
| Protein Sequence | MTAMKEDNAALITLKKNNDQEKLRVHKLTDASSNSADGFVINKAKNGGPLNKKSLVNNEQHIKKAVSPGRVRKHKTTTSSTKSRTKSKKKDASESKVQRENKGSFYQGAIFGSFLGAAVTTVLSNLAVKALQN | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 13 | Phosphorylation | EDNAALITLKKNNDQ CCCEEEEEEEECCHH | 33.12 | 27017623 | |
| 67 | Phosphorylation | QHIKKAVSPGRVRKH HHHHHHCCCCCCCCC | 26.88 | 24930733 | |
| 76 | Phosphorylation | GRVRKHKTTTSSTKS CCCCCCCCCCCCCCC | 34.72 | 28889911 | |
| 77 | Phosphorylation | RVRKHKTTTSSTKSR CCCCCCCCCCCCCCC | 29.50 | 28889911 | |
| 78 | Phosphorylation | VRKHKTTTSSTKSRT CCCCCCCCCCCCCCC | 26.38 | 28889911 | |
| 79 | Phosphorylation | RKHKTTTSSTKSRTK CCCCCCCCCCCCCCC | 33.64 | 28889911 | |
| 80 | Phosphorylation | KHKTTTSSTKSRTKS CCCCCCCCCCCCCCC | 37.45 | 28889911 | |
| 81 | Phosphorylation | HKTTTSSTKSRTKSK CCCCCCCCCCCCCCC | 32.57 | 28889911 | |
| 83 | Phosphorylation | TTTSSTKSRTKSKKK CCCCCCCCCCCCCCC | 45.32 | 28889911 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of PRM3_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of PRM3_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of PRM3_YEAST !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| PRM3_YEAST | PRM3 | physical | 10688190 | |
| KAR5_YEAST | KAR5 | physical | 19297527 | |
| RV167_YEAST | RVS167 | genetic | 20093466 | |
| TPA1_YEAST | TPA1 | genetic | 20093466 | |
| YGY5_YEAST | YGL235W | genetic | 20093466 | |
| PLMT_YEAST | OPI3 | genetic | 20093466 | |
| CYT2_YEAST | CYT2 | genetic | 20093466 | |
| RS3A1_YEAST | RPS1A | genetic | 20093466 | |
| KAR5_YEAST | KAR5 | genetic | 20093466 | |
| RAD1_YEAST | RAD1 | genetic | 20093466 | |
| MED1_YEAST | MED1 | genetic | 20093466 | |
| NPL4_YEAST | NPL4 | genetic | 27708008 | |
| REI1_YEAST | REI1 | genetic | 27708008 | |
| RV161_YEAST | RVS161 | genetic | 27708008 | |
| RV167_YEAST | RVS167 | genetic | 27708008 | |
| YGY5_YEAST | YGL235W | genetic | 27708008 | |
| QCR9_YEAST | QCR9 | genetic | 27708008 | |
| CYT2_YEAST | CYT2 | genetic | 27708008 | |
| RSSA2_YEAST | RPS0B | genetic | 27708008 | |
| SIC1_YEAST | SIC1 | genetic | 27708008 | |
| MMS22_YEAST | MMS22 | genetic | 27708008 | |
| KAR5_YEAST | KAR5 | genetic | 27708008 | |
| YOR31_YEAST | YOR131C | genetic | 27708008 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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