| UniProt ID | KAR5_YEAST | |
|---|---|---|
| UniProt AC | Q04746 | |
| Protein Name | Nuclear fusion protein KAR5 | |
| Gene Name | KAR5 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 504 | |
| Subcellular Localization |
Endoplasmic reticulum membrane Multi-pass membrane protein. Nucleus membrane Multi-pass membrane protein. |
|
| Protein Description | Required for nuclear membrane fusion during karyogamy.. | |
| Protein Sequence | MFEMRYVYLFAICIKFVSSSELGKINNLLQGRLIYTDNSVATNVLESKFPFLKSTCVKDALKLFLPQCIANGLESIDAETRVETAIKLSICEFQASGLGEIPENCMVDDLGSMMDCMFELESSSQWWTTYSGNYQRLSSICYENLLPFEKEQILKLFLNITELYDSFGDDVDTKLNHLMFQMEQDSQNFLDDLARMFRNYDNELRNATESNRIILENDLSFFRNKVNDVLYETSEQLEVQIIEKNSQLMNEVDTVHHIMSDLADELAKNDIKSKINDLKDDSLNNLQDLVEMSNDVKEYYSRNNKLVNTELENFSMGLKKQLGGMSKDLSESQMEAIELLQGFNSILHDSLLPSMTDEIVPEMTNFKNTLLQEWTAITSTLNGDFALWNEEIFSTFNDISEKLNGTKKKLDDIEIRVSLVHKNVMTMMRVLDFMWKTSKMIIRCGYLAVKNKYYWLLCSVVWIWSKYRTSRVNVKMIPIKRYYQWAALLLSIYLGAKTGSLIDF | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
|
|
||
* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 18 | Phosphorylation | AICIKFVSSSELGKI HHHHHHHCCHHHHHH | 31.14 | 28889911 | |
| 20 | Phosphorylation | CIKFVSSSELGKINN HHHHHCCHHHHHHHH | 29.36 | 28889911 | |
| 159 | N-linked_Glycosylation | QILKLFLNITELYDS HHHHHHHHHHHHHHH | 31.62 | - | |
| 206 | N-linked_Glycosylation | NYDNELRNATESNRI HHHHHHHCCCHHCCE | 64.93 | - | |
| 313 | N-linked_Glycosylation | LVNTELENFSMGLKK CCCHHHHHHHHHHHH | 47.09 | - | |
| 404 | N-linked_Glycosylation | NDISEKLNGTKKKLD HHHHHHHCCCCCCHH | 68.13 | - | |
| 426 | Phosphorylation | LVHKNVMTMMRVLDF HHHHHHHHHHHHHHH | 11.97 | 27017623 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of KAR5_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of KAR5_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of KAR5_YEAST !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| SPR3_YEAST | SPR3 | physical | 11087867 | |
| SMC2_YEAST | SMC2 | physical | 11087867 | |
| SMC3_YEAST | SMC3 | physical | 11087867 | |
| FMP27_YEAST | FMP27 | physical | 11087867 | |
| END3_YEAST | END3 | physical | 11087867 | |
| PMA1_YEAST | PMA1 | genetic | 16269340 | |
| ASI1_YEAST | ASI1 | genetic | 16269340 | |
| PRM3_YEAST | PRM3 | physical | 19297527 | |
| SEC66_YEAST | SEC66 | genetic | 10069807 | |
| PIN4_YEAST | PIN4 | genetic | 21987634 | |
| FZO1_YEAST | FZO1 | genetic | 21987634 | |
| RPB7_YEAST | RPB7 | genetic | 21987634 | |
| IPYR2_YEAST | PPA2 | genetic | 21987634 | |
| GEP3_YEAST | GEP3 | genetic | 21987634 | |
| SPR3_YEAST | SPR3 | physical | 22875988 | |
| YAJ9_YEAST | YAR029W | genetic | 27708008 | |
| REI1_YEAST | REI1 | genetic | 27708008 | |
| SSH1_YEAST | SSH1 | genetic | 27708008 | |
| VMA21_YEAST | VMA21 | genetic | 27708008 | |
| YHR2_YEAST | YHR112C | genetic | 27708008 | |
| EOS1_YEAST | EOS1 | genetic | 27708008 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
loading...
