| UniProt ID | ALAM_YEAST | |
|---|---|---|
| UniProt AC | P52893 | |
| Protein Name | Probable alanine aminotransferase, mitochondrial | |
| Gene Name | ALT1 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 592 | |
| Subcellular Localization | Mitochondrion matrix . | |
| Protein Description | ||
| Protein Sequence | MLSLSAKNHFTVSNSITHVIKSYHIRTLTSSAEKMPHITTPFSTSASSTKLKAFRKVRPVLQRHSSSWIVAQNHRRSLSGQSSLNDLRHLNRFPHHTLKTSNNEFYPAEQLTLEDVNENVLKAKYAVRGAIPMRAEELKAQLEKDPQSLPFDRIINANIGNPQQLQQKPLTYYRQVLSLLQYPELLNQNEQQLVDSKLFKLDAIKRAKSLMEDIGGSVGAYSSSQGVEGIRKSVAEFITKRDEGEISYPEDIFLTAGASAAVNYLLSIFCRGPETGVLIPIPQYPLYTATLALNNSQALPYYLDENSGWSTNPEEIETVVKEAIQNEIKPTVLVVINPGNPTGAVLSPESIAQIFEVAAKYGTVVIADEVYQENIFPGTKFHSMKKILRHLQREHPGKFDNVQLASLHSTSKGVSGECGQRGGYMELTGFSHEMRQVILKLASISLCPVVTGQALVDLMVRPPVEGEESFESDQAERNSIHEKLITRAMTLYETFNSLEGIECQKPQGAMYLFPKIDLPFKAVQEARHLELTPDEFYCKKLLESTGICTVPGSGFGQEPGTYHLRTTFLAPGLEWIKKWESFHKEFFDQYRD | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 40 | Phosphorylation | EKMPHITTPFSTSAS CCCCCCCCCCCCCCC | 23.02 | 28889911 | |
| 43 | Phosphorylation | PHITTPFSTSASSTK CCCCCCCCCCCCHHH | 23.74 | 21440633 | |
| 44 | Phosphorylation | HITTPFSTSASSTKL CCCCCCCCCCCHHHH | 28.79 | 27017623 | |
| 45 | Phosphorylation | ITTPFSTSASSTKLK CCCCCCCCCCHHHHH | 25.59 | 27017623 | |
| 47 | Phosphorylation | TPFSTSASSTKLKAF CCCCCCCCHHHHHHH | 38.00 | 21440633 | |
| 77 | Phosphorylation | VAQNHRRSLSGQSSL EEECCCCCCCCCCHH | 27.18 | 22369663 | |
| 79 | Phosphorylation | QNHRRSLSGQSSLND ECCCCCCCCCCHHHH | 35.71 | 22369663 | |
| 82 | Phosphorylation | RRSLSGQSSLNDLRH CCCCCCCCHHHHHHH | 40.08 | 22369663 | |
| 83 | Phosphorylation | RSLSGQSSLNDLRHL CCCCCCCHHHHHHHH | 24.25 | 22369663 | |
| 124 | Ubiquitination | NENVLKAKYAVRGAI CHHHHHHHHHHHCCC | 31.96 | 19722269 | |
| 144 | Acetylation | ELKAQLEKDPQSLPF HHHHHHHHCCCCCCH | 81.13 | 24489116 | |
| 168 | Acetylation | NPQQLQQKPLTYYRQ CHHHHHCCCCHHHHH | 29.09 | 24489116 | |
| 200 | Acetylation | LVDSKLFKLDAIKRA HHHHHHHHHHHHHHH | 56.76 | 24489116 | |
| 200 | Succinylation | LVDSKLFKLDAIKRA HHHHHHHHHHHHHHH | 56.76 | 23954790 | |
| 205 | Acetylation | LFKLDAIKRAKSLME HHHHHHHHHHHHHHH | 48.28 | 24489116 | |
| 398 | Acetylation | LQREHPGKFDNVQLA HHHHCCCCCCCEEEE | 54.73 | 24489116 | |
| 412 | N6-(pyridoxal phosphate)lysine | ASLHSTSKGVSGECG EECCCCCCCCCCCCH | 64.52 | - | |
| 412 | Other | ASLHSTSKGVSGECG EECCCCCCCCCCCCH | 64.52 | - | |
| 415 | Phosphorylation | HSTSKGVSGECGQRG CCCCCCCCCCCHHCC | 37.23 | 28889911 | |
| 483 | Acetylation | ERNSIHEKLITRAMT HHHHHHHHHHHHHHH | 30.90 | 24489116 | |
| 577 | Acetylation | APGLEWIKKWESFHK CCCCHHHHHHHHHHH | 53.56 | 24489116 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of ALAM_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of ALAM_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of ALAM_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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