TPT1_YEAST - dbPTM
TPT1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID TPT1_YEAST
UniProt AC Q12272
Protein Name tRNA 2'-phosphotransferase
Gene Name TPT1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 230
Subcellular Localization
Protein Description Catalyzes the last step of tRNA splicing, the transfer of the splice junction 2'-phosphate from ligated tRNA to NAD to produce ADP-ribose 1''-2'' cyclic phosphate..
Protein Sequence MRQVLQKDKRDVQLSKALSYLLRHTAVKEKLTIDSNGYTPLKELLSHNRLKTHKCTVDDIHRIVKENDKQRFHIKTLGADEEWICATQGHSIKSIQPSDEVLVPITEASQLPQELIHGTNLQSVIKIIESGAISPMSRNHVHLSPGMLHAKGVISGMRSSSNVYIFIDCHSPLFFQTLKMFRSLNNVYLSSSIPVELIQKVVVKGNLKDEEKLDTLRRILHERNIPLEKI
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
7Acetylation-MRQVLQKDKRDVQL
-CCHHHHHHHHHHHH		62.1425381059
19PhosphorylationVQLSKALSYLLRHTA
HHHHHHHHHHHHHHH		20.7021440633
130PhosphorylationSVIKIIESGAISPMS
HHHHHHHCCCCCCCC		24.1026447709
134PhosphorylationIIESGAISPMSRNHV
HHHCCCCCCCCCCCC		17.6426447709
137PhosphorylationSGAISPMSRNHVHLS
CCCCCCCCCCCCCCC		33.0626447709
151AcetylationSPGMLHAKGVISGMR
CCCHHHHHHHEECCC		42.8525381059
208AcetylationVVVKGNLKDEEKLDT
HEECCCCCCHHHHHH		68.0724489116
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of TPT1_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of TPT1_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of TPT1_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
FBRL_YEASTNOP1physical
11805837
RPF2_YEASTRPF2physical
11805837
NAT10_YEASTKRE33physical
11805837
DYR_YEASTDFR1genetic
27708008
ERD2_YEASTERD2genetic
27708008
GPI18_YEASTGPI18genetic
27708008
ALG14_YEASTALG14genetic
27708008
CKS1_YEASTCKS1genetic
27708008
CDC48_YEASTCDC48genetic
27708008
SC61G_YEASTSSS1genetic
27708008
TCPZ_YEASTCCT6genetic
27708008
COPB_YEASTSEC26genetic
27708008
GPI11_YEASTGPI11genetic
27708008
GPI8_YEASTGPI8genetic
27708008
GPI19_YEASTGPI19genetic
27708008
SEC20_YEASTSEC20genetic
27708008
MOB2_YEASTMOB2genetic
27708008
ACT_YEASTACT1genetic
27708008
PMM_YEASTSEC53genetic
27708008
STT3_YEASTSTT3genetic
27708008
HSF_YEASTHSF1genetic
27708008
GPI10_YEASTGPI10genetic
27708008
YIP1_YEASTYIP1genetic
27708008
GPI16_YEASTGPI16genetic
27708008
MET30_YEASTMET30genetic
27708008
OST1_YEASTOST1genetic
27708008
GRP78_YEASTKAR2genetic
27708008
GWT1_YEASTGWT1genetic
27708008
HSP77_YEASTSSC1genetic
27708008
SPC3_YEASTSPC3genetic
27708008
GAA1_YEASTGAA1genetic
27708008
CDC91_YEASTGAB1genetic
27708008
ERO1_YEASTERO1genetic
27708008
SEC59_YEASTSEC59genetic
27708008
RNT1_YEASTRNT1genetic
27708008
GPI12_YEASTGPI12genetic
27708008
GPI15_YEASTGPI15genetic
27708008
SEC12_YEASTSEC12genetic
27708008
SMP3_YEASTSMP3genetic
27708008
SEC63_YEASTSEC63genetic
27708008
GPI2_YEASTGPI2genetic
27708008
SEC62_YEASTSEC62genetic
27708008
BUR1_YEASTSGV1genetic
27708008
PRP4_YEASTPRP4genetic
27708008
DPM1_YEASTDPM1genetic
27708008
PMT2_YEASTPMT2genetic
27708008
GEM1_YEASTGEM1genetic
27708008
ALG3_YEASTALG3genetic
27708008
CSH1_YEASTCSH1genetic
27708008
SEC66_YEASTSEC66genetic
27708008
STE50_YEASTSTE50genetic
27708008
PER1_YEASTPER1genetic
27708008
ATG15_YEASTATG15genetic
27708008
RPN4_YEASTRPN4genetic
27708008
MTU1_YEASTSLM3genetic
27708008
OST4_YEASTOST4genetic
27708008
RM01_YEASTMRPL1genetic
27708008
TRM1_YEASTTRM1genetic
27708008
INO2_YEASTINO2genetic
27708008
MNN10_YEASTMNN10genetic
27708008
BCS1_YEASTBCS1genetic
27708008
GUP1_YEASTGUP1genetic
27708008
XRN1_YEASTXRN1genetic
27708008
TAN1_YEASTTAN1genetic
27708008
RTF1_YEASTRTF1genetic
27708008
VMA21_YEASTVMA21genetic
27708008
CHO2_YEASTCHO2genetic
27708008
FYV8_YEASTFYV8genetic
27708008
ALG10_YEASTDIE2genetic
27708008
TNA1_YEASTTNA1genetic
27708008
ERV29_YEASTERV29genetic
27708008
SDS3_YEASTSDS3genetic
27708008
FLX1_YEASTFLX1genetic
27708008
GPI7_YEASTLAS21genetic
27708008
ILM1_YEASTILM1genetic
27708008
LHS1_YEASTLHS1genetic
27708008
CYT2_YEASTCYT2genetic
27708008
RM49_YEASTMRP49genetic
27708008
UBI4P_YEASTUBI4genetic
27708008
COX12_YEASTCOX12genetic
27708008
CSF1_YEASTCSF1genetic
27708008
ARV1_YEASTARV1genetic
27708008
ATP10_YEASTATP10genetic
27708008
SPC2_YEASTSPC2genetic
27708008
UBX4_YEASTUBX4genetic
27708008
SCJ1_YEASTSCJ1genetic
27708008
EOS1_YEASTEOS1genetic
27708008
SWS2_YEASTSWS2genetic
27708008
ATP23_YEASTATP23genetic
27708008
ALG12_YEASTALG12genetic
27708008
CY1_YEASTCYT1genetic
27708008
ALG8_YEASTALG8genetic
27708008
OST3_YEASTOST3genetic
27708008
SYC1_YEASTSYC1genetic
27708008
MNE1_YEASTMNE1genetic
27708008
MSC6_YEASTMSC6genetic
27708008
COX10_YEASTCOX10genetic
27708008
ALG5_YEASTALG5genetic
27708008
YP089_YEASTYPR089Wgenetic
27708008
MSS18_YEASTMSS18genetic
27708008
KAR3_YEASTKAR3genetic
27708008
QCR2_YEASTQCR2genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of TPT1_YEAST

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Related Literatures of Post-Translational Modification

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