| UniProt ID | UBX4_YEAST | |
|---|---|---|
| UniProt AC | P54730 | |
| Protein Name | UBX domain-containing protein 4 | |
| Gene Name | UBX4 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 416 | |
| Subcellular Localization | Nucleus . Cytoplasm . | |
| Protein Description | Involved in CDC48-dependent protein degradation through the ubiquitin/proteasome pathway.. | |
| Protein Sequence | MPMVTVKYNFQLFKCKVSLNSTLNDVLHQSIQFFQLHTSSNDWSLIHLDKPVPLDLPWRLLNLPTGVNLELSKSSNFPVANKTNREDIPFNTIKIRFQIPGRDSVVKEMPSDQPIAPILRQMSGAAGDDFKIQVFSKIIEFKTIKDENLTLENLGIQEPSSVRLIFNNTSHSEGISANSAIHPKQTPPTMTNPETVASLPPHELHKPSVFLPSDEPLAVIKDQIEDEEDYELTVEQAKKYQKMLSSKAGTLGGPILTKRLREQSANNLPKKNKAISECLLRVKFPDRSHIQIAFKPNEDMRTVYNVVSQFLIDENMPFTLNQSHPFKPLAKDDKKLLDDLEFGSKTMLLFETNSNSNGPLIKAHLLEDAQKITHETRTTPSVNTINKSNPQGPSDNATSIKKTLNRVPKWMKLSKK | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 94 | Acetylation | DIPFNTIKIRFQIPG CCCCCEEEEEEECCC | 26.28 | 24489116 | |
| 245 | Phosphorylation | KKYQKMLSSKAGTLG HHHHHHHHCCCCCCC | 26.71 | 19823750 | |
| 246 | Phosphorylation | KYQKMLSSKAGTLGG HHHHHHHCCCCCCCH | 23.67 | 19823750 | |
| 250 | Phosphorylation | MLSSKAGTLGGPILT HHHCCCCCCCHHHHH | 27.39 | 19823750 | |
| 257 | Phosphorylation | TLGGPILTKRLREQS CCCHHHHHHHHHHHH | 18.16 | 19823750 | |
| 258 | Acetylation | LGGPILTKRLREQSA CCHHHHHHHHHHHHH | 46.09 | 25381059 | |
| 264 | Phosphorylation | TKRLREQSANNLPKK HHHHHHHHHCCCCCC | 28.36 | 23749301 | |
| 344 | Phosphorylation | LDDLEFGSKTMLLFE HHHHCCCCEEEEEEE | 30.21 | 22890988 | |
| 346 | Phosphorylation | DLEFGSKTMLLFETN HHCCCCEEEEEEEEC | 18.10 | 22890988 | |
| 352 | Phosphorylation | KTMLLFETNSNSNGP EEEEEEEECCCCCCC | 36.29 | 22890988 | |
| 354 | Phosphorylation | MLLFETNSNSNGPLI EEEEEECCCCCCCEE | 49.40 | 22890988 | |
| 356 | Phosphorylation | LFETNSNSNGPLIKA EEEECCCCCCCEEEE | 42.88 | 22890988 | |
| 381 | Phosphorylation | HETRTTPSVNTINKS CCCCCCCCCCCCCCC | 26.38 | 28889911 | |
| 384 | Phosphorylation | RTTPSVNTINKSNPQ CCCCCCCCCCCCCCC | 24.62 | 21440633 | |
| 388 | Phosphorylation | SVNTINKSNPQGPSD CCCCCCCCCCCCCCC | 49.61 | 19779198 | |
| 398 | Phosphorylation | QGPSDNATSIKKTLN CCCCCCHHHHHHHHH | 36.92 | 23749301 | |
| 399 | Phosphorylation | GPSDNATSIKKTLNR CCCCCHHHHHHHHHC | 29.96 | 23749301 | |
| 401 | Acetylation | SDNATSIKKTLNRVP CCCHHHHHHHHHCCC | 39.20 | 25381059 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of UBX4_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of UBX4_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of UBX4_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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| Phosphorylation | |
| Reference | PubMed |
| "A multidimensional chromatography technology for in-depthphosphoproteome analysis."; Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.; Mol. Cell. Proteomics 7:1389-1396(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-344, AND MASSSPECTROMETRY. | |
