EMC2_YEAST - dbPTM
EMC2_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID EMC2_YEAST
UniProt AC P47133
Protein Name ER membrane protein complex subunit 2
Gene Name EMC2
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 292
Subcellular Localization Endoplasmic reticulum .
Protein Description The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER)..
Protein Sequence MLKDLVREKLLTIMNTKAYTQFNPEQLLQLENEMKIYMKSGDSALTEGNYFFLMEMLFYVLVYRNQDVDAQVVYNTLRDRLGENSYKMVIMKATLLQINGNDKGAIEYLENLLNDDLEYETDFVTYVSIAKKLIAIKTTSKNLSQESVLKEVVALTDKFPLDAELWWYASEIYFEMGQFEKACYCLEQVLCITPFNYACFGRLSETLYYEALRSKKQTKTELLEKALKNALRSVELSELYLKGWALVNIISRELGRNKQNDLIKLSASKLKEISAKSNNKDKITAELILNKI
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
225AcetylationTKTELLEKALKNALR
CHHHHHHHHHHHHHH
60.0124489116

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of EMC2_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of EMC2_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of EMC2_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
SSH1_YEASTSSH1genetic
16269340
GET1_YEASTGET1genetic
16269340
ICE2_YEASTICE2genetic
16269340
STE24_YEASTSTE24genetic
16269340
SCS7_YEASTSCS7genetic
16269340
MNS1_YEASTMNS1genetic
16269340
TRS85_YEASTTRS85genetic
16269340
ERG2_YEASTERG2genetic
16269340
SUR2_YEASTSUR2genetic
16269340
ATC1_YEASTPMR1genetic
16269340
ERG4_YEASTERG4genetic
16269340
SIL1_YEASTSIL1genetic
16269340
GAS1_YEASTGAS1genetic
16269340
VPS51_YEASTVPS51genetic
19325107
HLJ1_YEASTHLJ1genetic
19325107
RPN4_YEASTRPN4genetic
19325107
SPC25_YEASTSPC25genetic
19325107
UBX4_YEASTUBX4genetic
19325107
SSH1_YEASTSSH1genetic
19325107
SRS2_YEASTSRS2genetic
21459050
POP4_YEASTPOP4genetic
21987634
SSH1_YEASTSSH1genetic
21987634
STE50_YEASTSTE50genetic
21987634
RS11A_YEASTRPS11Agenetic
21987634
RS11B_YEASTRPS11Agenetic
21987634
TPS2_YEASTTPS2genetic
21987634
TRS85_YEASTTRS85genetic
21987634
DOP1_YEASTDOP1genetic
21987634
IPK1_YEASTIPK1genetic
21987634
GET2_YEASTGET2genetic
21987634
ERG4_YEASTERG4genetic
21987634
GET1_YEASTGET1genetic
21987634
CHO2_YEASTCHO2genetic
21987634
ICE2_YEASTICE2genetic
21987634
RPA34_YEASTRPA34genetic
21987634
STE24_YEASTSTE24genetic
21987634
MNS1_YEASTMNS1genetic
21987634
VPH2_YEASTVPH2genetic
21987634
ARPC3_YEASTARC18genetic
21987634
ERG2_YEASTERG2genetic
21987634
APJ1_YEASTAPJ1genetic
21987634
INO4_YEASTINO4genetic
21987634
SYFM_YEASTMSF1genetic
21987634
GGPPS_YEASTBTS1genetic
27708008
KPC1_YEASTPKC1genetic
27708008
BRR6_YEASTBRR6genetic
27708008
DAM1_YEASTDAM1genetic
27708008
CP51_YEASTERG11genetic
27708008
BRL1_YEASTBRL1genetic
27708008
SSH1_YEASTSSH1genetic
27708008
RV161_YEASTRVS161genetic
27708008
RPN4_YEASTRPN4genetic
27708008
PEX19_YEASTPEX19genetic
27708008
OST4_YEASTOST4genetic
27708008
INO2_YEASTINO2genetic
27708008
ARO1_YEASTARO1genetic
27708008
AAKG_YEASTSNF4genetic
27708008
CHO2_YEASTCHO2genetic
27708008
SMI1_YEASTSMI1genetic
27708008
ICE2_YEASTICE2genetic
27708008
DAL81_YEASTDAL81genetic
27708008
GPX1_YEASTGPX1genetic
27708008
VRP1_YEASTVRP1genetic
27708008
MSC1_YEASTMSC1genetic
27708008
TRM10_YEASTTRM10genetic
27708008
CY1_YEASTCYT1genetic
27708008
AIM44_YEASTAIM44genetic
27708008
NIP80_YEASTNIP100genetic
27708008
USBP1_HUMANUSHBP1physical
27107014
MEOX2_HUMANMEOX2physical
27107014
RV161_YEASTRVS161genetic
29674565
CHO2_YEASTCHO2genetic
29674565
SLT2_YEASTSLT2genetic
29674565
BRL1_YEASTBRL1genetic
29674565
SPT23_YEASTSPT23genetic
29674565
CAP_YEASTSRV2genetic
29674565
GGPPS_YEASTBTS1genetic
29674565
PAN1_YEASTPAN1genetic
29674565
KPC1_YEASTPKC1genetic
29674565
TRS20_YEASTTRS20genetic
29674565
THRC_YEASTTHR4genetic
29674565
APC11_YEASTAPC11genetic
29674565
INO2_YEASTINO2genetic
29674565
NBP2_YEASTNBP2genetic
29674565
GET2_YEASTGET2genetic
29674565
GET1_YEASTGET1genetic
29674565
ICE2_YEASTICE2genetic
29674565
STS1_YEASTSTS1genetic
29674565
GWT1_YEASTGWT1genetic
29674565
HS150_YEASTHSP150genetic
29674565
BET3_YEASTBET3genetic
29674565
MOT3_YEASTMOT3genetic
29674565
SSO2_YEASTSSO2genetic
29674565
TLG2_YEASTTLG2genetic
29674565
BEM3_YEASTBEM3genetic
29674565
NAB3_YEASTNAB3genetic
29674565
SSO1_YEASTSSO1genetic
29674565
CALM_YEASTCMD1genetic
29674565
NUM1_YEASTNUM1genetic
29674565
SWR1_YEASTSWR1genetic
29674565
LDB18_YEASTLDB18genetic
29674565
MDY2_YEASTMDY2genetic
29674565
LIS1_YEASTPAC1genetic
29674565

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of EMC2_YEAST

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Related Literatures of Post-Translational Modification

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