| UniProt ID | NUM1_YEAST | |
|---|---|---|
| UniProt AC | Q00402 | |
| Protein Name | Nuclear migration protein NUM1 | |
| Gene Name | NUM1 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 2748 | |
| Subcellular Localization | Bud tip . | |
| Protein Description | Controls nuclear migration. NUM1 specifically controls the interaction of the bud neck cytoskeleton with the pre-divisional G2 nucleus. Functions in dynein-anchoring. During late anaphase forms dynein-interacting cortical microtubule capture sites at both cellular poles. This leads to dynein-dependent sliding of the microtubules in the bud.. | |
| Protein Sequence | MSHNNRHKKNNDKDSSAGQYANSIDNSLSQESVSTNGVTRMANLKADECGSGDEGDKTKRFSISSILSKRETKDVLPEFAGSSSHNGVLTANSSKDMNFTLELSENLLVECRKLQSSNEAKNEQIKSLKQIKESLSDKIEELTNQKKSFMKELDSTKDLNWDLESKLTNLSMECRQLKELKKKTEKSWNDEKESLKLLKTDLEILTLTKNGMENDLSSQKLHYDKEISELKERILDLNNENDRLLISVSDLTSEINSLQSNRTERIKIQKQLDDAKASISSLKRKVQKKYYQKQHTSDTTVTSDPDSEGTTSEEDIFDIVIEIDHMIETGPSVEDISEDLVKKYSEKNNMILLSNDSYKNLLQKSESASKPKDDELMTKEVAENLNMIALPNDDNYSKKEFSLESHIKYLEASGYKVLPLEEFENLNESLSNPSYNYLKEKLQALKKIPIDQSTFNLLKEPTIDFLLPLTSKIDCLIIPTKDYNDLFESVKNPSIEQMKKCLEAKNDLQSNICKWLEERNGCKWLSNDLYFSMVNKIETPSKQYLSDKAKEYDQVLIDTKALEGLKNPTIDFLREKASASDYLLLKKEDYVSPSLEYLVEHAKATNHHLLSDSAYEDLVKCKENPDMEFLKEKSAKLGHTVVSNEAYSELEKKLEQPSLEYLVEHAKATNHHLLSDSAYEDLVKCKENPDMEFLKEKSAKLGHTVVSNEAYSELQRKYSELEKEVEQPSLAYLVEHAKATDHHLLSDSAYEDLVKCKENPDVEFLKEKSAKLGHTVVSSEEYSELQRKYSELEKEVEQPSLAYLVEHAKATDHHLLSDSAYEELVKCKENPDMEFLKEKSAKLGHTVVSNEAYSELEKKLEQPSLAYLVEHAKATDHHLLSDSAYEDLVKCKENSDVEFLKEKSAKLGHTVVSNEAYSELEKKLEQPSLAYLVEHAKATDHHLLSDSAYEDLVKCKENPDMEFLKEKSAKLGHTVVSNEAYSELEKKLEQPSLEYLVEHAKATNHHLLSDSAYEDLVKCKENPDMEFLKEKSAKLGHTVVSNEAYSELEKKLEQPSLEYLVEHAKATNHHLLSDSAYEELVKCKENPDVEFLKEKSAKLGHTVVSNEAYSELEKKLEQPSLEYLVEHAKATNHHLLSDSAYEELVKCKENPDVEFLKEKSAKLGHTVVSNEAYSELEKKLEQPSLAYLVEHAKATDHHLLSDSAYEDLVKCKENPDVEFLKEKSAKLGHTVVSNEAYSELEKKLEQPSLAYLVEHAKATDHHLLSDSAYEDLVKCKENPDMEFLKEKSAKLGHTVVSNEAYSELEKKLEQPSLEYLVEHAKATNHHLLSDSAYEDLVKCKENPDMEFLKEKSAKLGHTVVSNKEYSELEKKLEQPSLEYLVKHAEQIQSKIISISDFNTLANPSMEDMASKLQKLEYQIVSNDEYIALKNTMEKPDVELLRSKLKGYHIIDTTTYNELVSNFNSPTLKFIEEKAKSKGYRLIEPNEYLDLNRIATTPSKEEIDNFCKQIGCYALDSKEYERLKNSLENPSKKFIEENAALLDLVLVDKTEYQAMKDNASNKKSLIPSTKALDFVTMPAPQLASAEKSSLQKRTLSDIENELKALGYVAIRKENLPNLEKPIVDNASKNDVLNLCSKFSLVPLSTEEYDNMRKEHTKILNILGDPSIDFLKEKCEKYQMLIISKHDYEEKQEAIENPGYEFILEKASALGYELVSEVELDRMKQMIDSPDIDYMQEKAARNEMVLLRNEEKEALQKKIEYPSLTFLIEKAAGMNKILVDQIEYDETIRKCNHPTRMELEESCHHLNLVLLDQNEYSTLREPLENRNVEDLINTLSKLNYIAIPNTIYQDLIGKYENPNFDYLKDSLNKMDYVAISRQDYELMVAKYEKPQLDYLKISSEKIDHIVVPLSEYNLMVTNYRNPSLSYLKEKAVLNNHILIKEDDYKNILAVSEHPTVIHLSEKASLLNKVLVDKDDFATMSRSIEKPTIDFLSTKALSMGKILVNESTHKRNEKLLSEPDSEFLTMKAKEQGLIIISEKEYSELRDQIDRPSLDVLKEKAAIFDSIIVENIEYQQLVNTTSPCPPITYEDLKVYAHQFGMELCLQKPNKLSGAERAERIDEQSINTTSSNSTTTSSMFTDALDDNIEELNRVELQNNEDYTDIISKSSTVKDATIFIPAYENIKNSAEKLGYKLVPFEKSNINLKNIEAPLFSKDNDDTSVASSIDLDHLSRKAEKYGMTLISDQEFEEYHILKDNAVNLNGGMEEMNNPLSENQNLAAKTTNTAQEGAFQNTVPHNDMDNEEVEYGPDDPTFTVRQLKKPAGDRNLILTSREKTLLSRDDNIMSQNEAVYGDDISDSFVDESQEIKNDVDIIKTQAMKYGMLCIPESNFVGASYASAQDMSDIVVLSASYYHNLMSPEDMKWNCVSNEELQAEVKKRGLQIALTTKEDKKGQATASKHEYVSHKLNNKTSTVSTKSGAKKGLAEAAATTAYEDSESHPQIEEQSHRTNHHKHHKRQQSLNSNSTSKTTHSSRNTPASRRDIVASFMSRAGSASRTASLQTLASLNEPSIIPALTQTVIGEYLFKYYPRLGPFGFESRHERFFWVHPYTLTLYWSASNPILENPANTKTKGVAILGVESVTDPNPYPTGLYHKSIVVTTETRTIKFTCPTRQRHNIWYNSLRYLLQRNMQGISLEDIADDPTDNMYSGKIFPLPGENTKSSSKRLSASRRSVSTRSLRHRVPQSRSFGNLR | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 20 | Phosphorylation | KDSSAGQYANSIDNS CCCHHHHHHHHHCCC | 13.56 | 28889911 | |
| 23 | Phosphorylation | SAGQYANSIDNSLSQ HHHHHHHHHCCCCCC | 24.13 | 21440633 | |
| 27 | Phosphorylation | YANSIDNSLSQESVS HHHHHCCCCCCCCCC | 26.16 | 22369663 | |
| 29 | Phosphorylation | NSIDNSLSQESVSTN HHHCCCCCCCCCCCC | 31.55 | 22369663 | |
| 32 | Phosphorylation | DNSLSQESVSTNGVT CCCCCCCCCCCCCCC | 17.46 | 22369663 | |
| 34 | Phosphorylation | SLSQESVSTNGVTRM CCCCCCCCCCCCCHH | 25.98 | 22369663 | |
| 35 | Phosphorylation | LSQESVSTNGVTRMA CCCCCCCCCCCCHHC | 33.56 | 21440633 | |
| 39 | Phosphorylation | SVSTNGVTRMANLKA CCCCCCCCHHCCCCC | 19.00 | 22369663 | |
| 51 | Phosphorylation | LKADECGSGDEGDKT CCCCCCCCCCCCCCC | 55.52 | 23749301 | |
| 58 | Phosphorylation | SGDEGDKTKRFSISS CCCCCCCCCCEEHHH | 31.99 | 28889911 | |
| 62 | Phosphorylation | GDKTKRFSISSILSK CCCCCCEEHHHHHHC | 26.12 | 22369663 | |
| 64 | Phosphorylation | KTKRFSISSILSKRE CCCCEEHHHHHHCCC | 15.32 | 22369663 | |
| 65 | Phosphorylation | TKRFSISSILSKRET CCCEEHHHHHHCCCC | 26.36 | 22369663 | |
| 68 | Phosphorylation | FSISSILSKRETKDV EEHHHHHHCCCCCCC | 28.17 | 28889911 | |
| 69 | Ubiquitination | SISSILSKRETKDVL EHHHHHHCCCCCCCC | 51.30 | 24961812 | |
| 72 | Phosphorylation | SILSKRETKDVLPEF HHHHCCCCCCCCHHC | 36.26 | 24961812 | |
| 136 | Phosphorylation | KQIKESLSDKIEELT HHHHHHHHHHHHHHH | 46.25 | 21440633 | |
| 138 | Acetylation | IKESLSDKIEELTNQ HHHHHHHHHHHHHHH | 48.95 | 24489116 | |
| 143 | Phosphorylation | SDKIEELTNQKKSFM HHHHHHHHHHHHHHH | 38.59 | 25005228 | |
| 148 | Phosphorylation | ELTNQKKSFMKELDS HHHHHHHHHHHHHHC | 37.29 | 25005228 | |
| 209 | Ubiquitination | LEILTLTKNGMENDL HHHHHHCCCCCCCCC | 55.40 | 23749301 | |
| 225 | Acetylation | SQKLHYDKEISELKE HCCCCCCHHHHHHHH | 50.18 | 24489116 | |
| 231 | Acetylation | DKEISELKERILDLN CHHHHHHHHHHHHCC | 40.68 | 24489116 | |
| 354 | Phosphorylation | KNNMILLSNDSYKNL HCCEEEECCHHHHHH | 34.84 | 22369663 | |
| 357 | Phosphorylation | MILLSNDSYKNLLQK EEEECCHHHHHHHHH | 42.11 | 22369663 | |
| 358 | Phosphorylation | ILLSNDSYKNLLQKS EEECCHHHHHHHHHH | 13.52 | 21440633 | |
| 367 | Phosphorylation | NLLQKSESASKPKDD HHHHHHHHCCCCCCC | 44.95 | 30377154 | |
| 416 | Ubiquitination | YLEASGYKVLPLEEF HHHHCCCEEEEHHHH | 40.60 | 17644757 | |
| 439 | Ubiquitination | NPSYNYLKEKLQALK CCCHHHHHHHHHHHH | 42.30 | 17644757 | |
| 526 | Phosphorylation | RNGCKWLSNDLYFSM HCCCEECCCCHHHHH | 27.47 | 19779198 | |
| 532 | Phosphorylation | LSNDLYFSMVNKIET CCCCHHHHHHHCCCC | 14.31 | 19779198 | |
| 542 | Ubiquitination | NKIETPSKQYLSDKA HCCCCCCHHHHCHHH | 44.13 | 23749301 | |
| 546 | Phosphorylation | TPSKQYLSDKAKEYD CCCHHHHCHHHHHHH | 31.93 | 19779198 | |
| 603 | Ubiquitination | EYLVEHAKATNHHLL HHHHHHHHHCCCCCC | 58.62 | 17644757 | |
| 611 | Phosphorylation | ATNHHLLSDSAYEDL HCCCCCCCCHHHHHH | 35.56 | 28889911 | |
| 613 | Phosphorylation | NHHLLSDSAYEDLVK CCCCCCCHHHHHHHH | 29.40 | 28889911 | |
| 620 | Ubiquitination | SAYEDLVKCKENPDM HHHHHHHHCCCCCCH | 47.05 | 17644757 | |
| 636 | Acetylation | FLKEKSAKLGHTVVS HHHHHHHHHCCEECC | 63.19 | 24489116 | |
| 636 | Ubiquitination | FLKEKSAKLGHTVVS HHHHHHHHHCCEECC | 63.19 | 17644757 | |
| 647 | Phosphorylation | TVVSNEAYSELEKKL EECCHHHHHHHHHHH | 9.12 | 24961812 | |
| 648 | Phosphorylation | VVSNEAYSELEKKLE ECCHHHHHHHHHHHC | 42.63 | 21440633 | |
| 652 | Acetylation | EAYSELEKKLEQPSL HHHHHHHHHHCCCCH | 75.24 | 24489116 | |
| 652 | Ubiquitination | EAYSELEKKLEQPSL HHHHHHHHHHCCCCH | 75.24 | 17644757 | |
| 653 | Ubiquitination | AYSELEKKLEQPSLE HHHHHHHHHCCCCHH | 48.13 | 17644757 | |
| 658 | Phosphorylation | EKKLEQPSLEYLVEH HHHHCCCCHHHHHHH | 33.26 | 21440633 | |
| 667 | Ubiquitination | EYLVEHAKATNHHLL HHHHHHHHHCCCCCC | 58.62 | 17644757 | |
| 675 | Phosphorylation | ATNHHLLSDSAYEDL HCCCCCCCCHHHHHH | 35.56 | 28889911 | |
| 677 | Phosphorylation | NHHLLSDSAYEDLVK CCCCCCCHHHHHHHH | 29.40 | 28889911 | |
| 684 | Ubiquitination | SAYEDLVKCKENPDM HHHHHHHHCCCCCCH | 47.05 | 17644757 | |
| 700 | Ubiquitination | FLKEKSAKLGHTVVS HHHHHHHHHCCCHHC | 63.19 | 17644757 | |
| 717 | Ubiquitination | AYSELQRKYSELEKE HHHHHHHHHHHHHHH | 39.92 | 17644757 | |
| 719 | Phosphorylation | SELQRKYSELEKEVE HHHHHHHHHHHHHCC | 38.45 | 27214570 | |
| 723 | Acetylation | RKYSELEKEVEQPSL HHHHHHHHHCCCCCH | 78.62 | 24489116 | |
| 738 | Ubiquitination | AYLVEHAKATDHHLL HHHHHHHHCCCCCCC | 54.44 | 17644757 | |
| 740 | Phosphorylation | LVEHAKATDHHLLSD HHHHHHCCCCCCCCC | 34.85 | 19823750 | |
| 746 | Phosphorylation | ATDHHLLSDSAYEDL CCCCCCCCCHHHHHH | 35.56 | 21440633 | |
| 748 | Phosphorylation | DHHLLSDSAYEDLVK CCCCCCCHHHHHHHH | 29.40 | 20377248 | |
| 750 | Phosphorylation | HLLSDSAYEDLVKCK CCCCCHHHHHHHHCC | 17.58 | 19823750 | |
| 755 | Ubiquitination | SAYEDLVKCKENPDV HHHHHHHHCCCCCCH | 47.05 | 17644757 | |
| 766 | Acetylation | NPDVEFLKEKSAKLG CCCHHHHHHHHHHHC | 69.30 | 24489116 | |
| 790 | Phosphorylation | SELQRKYSELEKEVE HHHHHHHHHHHHHCC | 38.45 | 27214570 | |
| 842 | Ubiquitination | FLKEKSAKLGHTVVS HHHHHHHHHCCEECC | 63.19 | 17644757 | |
| 853 | Phosphorylation | TVVSNEAYSELEKKL EECCHHHHHHHHHHH | 9.12 | 24961812 | |
| 854 | Phosphorylation | VVSNEAYSELEKKLE ECCHHHHHHHHHHHC | 42.63 | 21440633 | |
| 858 | Ubiquitination | EAYSELEKKLEQPSL HHHHHHHHHHCCCCH | 75.24 | 17644757 | |
| 859 | Ubiquitination | AYSELEKKLEQPSLA HHHHHHHHHCCCCHH | 48.13 | 17644757 | |
| 873 | Ubiquitination | AYLVEHAKATDHHLL HHHHHHHHCCCCCCC | 54.44 | 17644757 | |
| 875 | Phosphorylation | LVEHAKATDHHLLSD HHHHHHCCCCCCCCC | 34.85 | 19823750 | |
| 881 | Phosphorylation | ATDHHLLSDSAYEDL CCCCCCCCCHHHHHH | 35.56 | 21440633 | |
| 883 | Phosphorylation | DHHLLSDSAYEDLVK CCCCCCCHHHHHHHH | 29.40 | 20377248 | |
| 885 | Phosphorylation | HLLSDSAYEDLVKCK CCCCCHHHHHHHHCC | 17.58 | 19823750 | |
| 890 | Ubiquitination | SAYEDLVKCKENSDV HHHHHHHHCCCCCCC | 47.05 | 17644757 | |
| 895 | Phosphorylation | LVKCKENSDVEFLKE HHHCCCCCCCHHHHH | 44.09 | 25704821 | |
| 906 | Ubiquitination | FLKEKSAKLGHTVVS HHHHHHHHHCCEEEC | 63.19 | 17644757 | |
| 917 | Phosphorylation | TVVSNEAYSELEKKL EEECHHHHHHHHHHH | 9.12 | 24961812 | |
| 918 | Phosphorylation | VVSNEAYSELEKKLE EECHHHHHHHHHHHC | 42.63 | 21440633 | |
| 922 | Ubiquitination | EAYSELEKKLEQPSL HHHHHHHHHHCCCCH | 75.24 | 17644757 | |
| 923 | Ubiquitination | AYSELEKKLEQPSLA HHHHHHHHHCCCCHH | 48.13 | 17644757 | |
| 937 | Ubiquitination | AYLVEHAKATDHHLL HHHHHHHHCCCCCCC | 54.44 | 17644757 | |
| 939 | Phosphorylation | LVEHAKATDHHLLSD HHHHHHCCCCCCCCC | 34.85 | 19823750 | |
| 945 | Phosphorylation | ATDHHLLSDSAYEDL CCCCCCCCCHHHHHH | 35.56 | 21440633 | |
| 947 | Phosphorylation | DHHLLSDSAYEDLVK CCCCCCCHHHHHHHH | 29.40 | 20377248 | |
| 949 | Phosphorylation | HLLSDSAYEDLVKCK CCCCCHHHHHHHHCC | 17.58 | 19823750 | |
| 954 | Ubiquitination | SAYEDLVKCKENPDM HHHHHHHHCCCCCCH | 47.05 | 17644757 | |
| 970 | Ubiquitination | FLKEKSAKLGHTVVS HHHHHHHHHCCEECC | 63.19 | 17644757 | |
| 981 | Phosphorylation | TVVSNEAYSELEKKL EECCHHHHHHHHHHH | 9.12 | 24961812 | |
| 982 | Phosphorylation | VVSNEAYSELEKKLE ECCHHHHHHHHHHHC | 42.63 | 21440633 | |
| 986 | Ubiquitination | EAYSELEKKLEQPSL HHHHHHHHHHCCCCH | 75.24 | 17644757 | |
| 987 | Ubiquitination | AYSELEKKLEQPSLE HHHHHHHHHCCCCHH | 48.13 | 17644757 | |
| 992 | Phosphorylation | EKKLEQPSLEYLVEH HHHHCCCCHHHHHHH | 33.26 | 21440633 | |
| 1001 | Ubiquitination | EYLVEHAKATNHHLL HHHHHHHHHCCCCCC | 58.62 | 17644757 | |
| 1009 | Phosphorylation | ATNHHLLSDSAYEDL HCCCCCCCCHHHHHH | 35.56 | 28889911 | |
| 1011 | Phosphorylation | NHHLLSDSAYEDLVK CCCCCCCHHHHHHHH | 29.40 | 28889911 | |
| 1018 | Ubiquitination | SAYEDLVKCKENPDM HHHHHHHHCCCCCCH | 47.05 | 17644757 | |
| 1034 | Ubiquitination | FLKEKSAKLGHTVVS HHHHHHHHHCCEECC | 63.19 | 17644757 | |
| 1045 | Phosphorylation | TVVSNEAYSELEKKL EECCHHHHHHHHHHH | 9.12 | 24961812 | |
| 1046 | Phosphorylation | VVSNEAYSELEKKLE ECCHHHHHHHHHHHC | 42.63 | 21440633 | |
| 1050 | Ubiquitination | EAYSELEKKLEQPSL HHHHHHHHHHCCCCH | 75.24 | 17644757 | |
| 1051 | Ubiquitination | AYSELEKKLEQPSLE HHHHHHHHHCCCCHH | 48.13 | 17644757 | |
| 1056 | Phosphorylation | EKKLEQPSLEYLVEH HHHHCCCCHHHHHHH | 33.26 | 21440633 | |
| 1065 | Ubiquitination | EYLVEHAKATNHHLL HHHHHHHHHCCCCCC | 58.62 | 17644757 | |
| 1098 | Ubiquitination | FLKEKSAKLGHTVVS HHHHHHHHHCCEEEC | 63.19 | 17644757 | |
| 1109 | Phosphorylation | TVVSNEAYSELEKKL EEECHHHHHHHHHHH | 9.12 | 24961812 | |
| 1110 | Phosphorylation | VVSNEAYSELEKKLE EECHHHHHHHHHHHC | 42.63 | 21440633 | |
| 1114 | Ubiquitination | EAYSELEKKLEQPSL HHHHHHHHHHCCCCH | 75.24 | 17644757 | |
| 1115 | Ubiquitination | AYSELEKKLEQPSLE HHHHHHHHHCCCCHH | 48.13 | 17644757 | |
| 1120 | Phosphorylation | EKKLEQPSLEYLVEH HHHHCCCCHHHHHHH | 33.26 | 21440633 | |
| 1129 | Ubiquitination | EYLVEHAKATNHHLL HHHHHHHHHCCCCCC | 58.62 | 17644757 | |
| 1162 | Ubiquitination | FLKEKSAKLGHTVVS HHHHHHHHHCCEEEC | 63.19 | 17644757 | |
| 1173 | Phosphorylation | TVVSNEAYSELEKKL EEECHHHHHHHHHHH | 9.12 | 24961812 | |
| 1174 | Phosphorylation | VVSNEAYSELEKKLE EECHHHHHHHHHHHC | 42.63 | 21440633 | |
| 1178 | Ubiquitination | EAYSELEKKLEQPSL HHHHHHHHHHCCCCH | 75.24 | 17644757 | |
| 1179 | Ubiquitination | AYSELEKKLEQPSLA HHHHHHHHHCCCCHH | 48.13 | 17644757 | |
| 1193 | Ubiquitination | AYLVEHAKATDHHLL HHHHHHHHCCCCCCC | 54.44 | 17644757 | |
| 1195 | Phosphorylation | LVEHAKATDHHLLSD HHHHHHCCCCCCCCC | 34.85 | 19823750 | |
| 1201 | Phosphorylation | ATDHHLLSDSAYEDL CCCCCCCCCHHHHHH | 35.56 | 21440633 | |
| 1203 | Phosphorylation | DHHLLSDSAYEDLVK CCCCCCCHHHHHHHH | 29.40 | 20377248 | |
| 1205 | Phosphorylation | HLLSDSAYEDLVKCK CCCCCHHHHHHHHCC | 17.58 | 19823750 | |
| 1210 | Ubiquitination | SAYEDLVKCKENPDV HHHHHHHHCCCCCCH | 47.05 | 17644757 | |
| 1226 | Ubiquitination | FLKEKSAKLGHTVVS HHHHHHHHHCCEEEC | 63.19 | 17644757 | |
| 1237 | Phosphorylation | TVVSNEAYSELEKKL EEECHHHHHHHHHHH | 9.12 | 24961812 | |
| 1238 | Phosphorylation | VVSNEAYSELEKKLE EECHHHHHHHHHHHC | 42.63 | 21440633 | |
| 1242 | Ubiquitination | EAYSELEKKLEQPSL HHHHHHHHHHCCCCH | 75.24 | 17644757 | |
| 1243 | Ubiquitination | AYSELEKKLEQPSLA HHHHHHHHHCCCCHH | 48.13 | 17644757 | |
| 1257 | Ubiquitination | AYLVEHAKATDHHLL HHHHHHHHCCCCCCC | 54.44 | 17644757 | |
| 1259 | Phosphorylation | LVEHAKATDHHLLSD HHHHHHCCCCCCCCC | 34.85 | 19823750 | |
| 1265 | Phosphorylation | ATDHHLLSDSAYEDL CCCCCCCCCHHHHHH | 35.56 | 21440633 | |
| 1267 | Phosphorylation | DHHLLSDSAYEDLVK CCCCCCCHHHHHHHH | 29.40 | 20377248 | |
| 1269 | Phosphorylation | HLLSDSAYEDLVKCK CCCCCHHHHHHHHCC | 17.58 | 19823750 | |
| 1274 | Ubiquitination | SAYEDLVKCKENPDM HHHHHHHHCCCCCCH | 47.05 | 17644757 | |
| 1290 | Ubiquitination | FLKEKSAKLGHTVVS HHHHHHHHHCCEECC | 63.19 | 17644757 | |
| 1301 | Phosphorylation | TVVSNEAYSELEKKL EECCHHHHHHHHHHH | 9.12 | 24961812 | |
| 1302 | Phosphorylation | VVSNEAYSELEKKLE ECCHHHHHHHHHHHC | 42.63 | 21440633 | |
| 1306 | Ubiquitination | EAYSELEKKLEQPSL HHHHHHHHHHCCCCH | 75.24 | 17644757 | |
| 1307 | Ubiquitination | AYSELEKKLEQPSLE HHHHHHHHHCCCCHH | 48.13 | 17644757 | |
| 1312 | Phosphorylation | EKKLEQPSLEYLVEH HHHHCCCCHHHHHHH | 33.26 | 21440633 | |
| 1321 | Ubiquitination | EYLVEHAKATNHHLL HHHHHHHHHCCCCCC | 58.62 | 17644757 | |
| 1329 | Phosphorylation | ATNHHLLSDSAYEDL HCCCCCCCCHHHHHH | 35.56 | 28889911 | |
| 1331 | Phosphorylation | NHHLLSDSAYEDLVK CCCCCCCHHHHHHHH | 29.40 | 28889911 | |
| 1338 | Ubiquitination | SAYEDLVKCKENPDM HHHHHHHHCCCCCCH | 47.05 | 17644757 | |
| 1382 | Acetylation | PSLEYLVKHAEQIQS CCHHHHHHHHHHHHH | 34.21 | 24489116 | |
| 1389 | Phosphorylation | KHAEQIQSKIISISD HHHHHHHHHEEEHHH | 27.70 | 19779198 | |
| 1404 | Phosphorylation | FNTLANPSMEDMASK HCCCCCCCHHHHHHH | 34.31 | 19779198 | |
| 1460 | Phosphorylation | TTYNELVSNFNSPTL CCHHHHHHCCCCCHH | 48.61 | 25521595 | |
| 1464 | Phosphorylation | ELVSNFNSPTLKFIE HHHHCCCCCHHHHHH | 18.35 | 22369663 | |
| 1466 | Phosphorylation | VSNFNSPTLKFIEEK HHCCCCCHHHHHHHH | 42.26 | 22369663 | |
| 1495 | Phosphorylation | LDLNRIATTPSKEEI CCCCCCCCCCCHHHH | 36.55 | 19779198 | |
| 1498 | Phosphorylation | NRIATTPSKEEIDNF CCCCCCCCHHHHHHH | 51.08 | 19779198 | |
| 1593 | Phosphorylation | KSSLQKRTLSDIENE HHHHHHCCHHHHHHH | 37.33 | 21440633 | |
| 1595 | Phosphorylation | SLQKRTLSDIENELK HHHHCCHHHHHHHHH | 35.61 | 25752575 | |
| 1638 | Phosphorylation | LNLCSKFSLVPLSTE HHHHHCCCCCCCCHH | 31.99 | 28889911 | |
| 1643 | Phosphorylation | KFSLVPLSTEEYDNM CCCCCCCCHHHHHHH | 27.92 | 28889911 | |
| 1647 | Phosphorylation | VPLSTEEYDNMRKEH CCCCHHHHHHHHHHH | 13.34 | 28889911 | |
| 1689 | Acetylation | SKHDYEEKQEAIENP ECCCHHHHHHHHHCC | 41.31 | 24489116 | |
| 1706 | Phosphorylation | EFILEKASALGYELV HHHHHHHHHCCCCHH | 34.78 | 19779198 | |
| 1732 | Phosphorylation | IDSPDIDYMQEKAAR HCCCCHHHHHHHHHH | 10.88 | 28889911 | |
| 1750 | Ubiquitination | VLLRNEEKEALQKKI EEECHHHHHHHHHHC | 41.95 | 23749301 | |
| 1867 | Ubiquitination | YLKDSLNKMDYVAIS HHHHHHCCCCEEEEE | 38.14 | 23749301 | |
| 1874 | Phosphorylation | KMDYVAISRQDYELM CCCEEEEEHHHHEEH | 17.72 | 25882841 | |
| 1908 | Phosphorylation | DHIVVPLSEYNLMVT CEEEEEHHHHCEEEE | 31.78 | 19779198 | |
| 1917 | Phosphorylation | YNLMVTNYRNPSLSY HCEEEECCCCCCHHH | 11.47 | 19779198 | |
| 1921 | Phosphorylation | VTNYRNPSLSYLKEK EECCCCCCHHHHHHH | 33.23 | 27214570 | |
| 1983 | Acetylation | TMSRSIEKPTIDFLS HHCCCCCCCCCCHHH | 45.88 | 24489116 | |
| 2014 | Phosphorylation | KRNEKLLSEPDSEFL HHCHHHCCCCCCHHC | 58.48 | 28889911 | |
| 2018 | Phosphorylation | KLLSEPDSEFLTMKA HHCCCCCCHHCHHHH | 40.75 | 28889911 | |
| 2022 | Phosphorylation | EPDSEFLTMKAKEQG CCCCHHCHHHHHHCC | 23.19 | 28889911 | |
| 2078 | Phosphorylation | QQLVNTTSPCPPITY HHHCCCCCCCCCCCH | 23.59 | 27214570 | |
| 2158 | Phosphorylation | LQNNEDYTDIISKSS CCCCCCCCHHHCCCC | 32.80 | 19779198 | |
| 2162 | Phosphorylation | EDYTDIISKSSTVKD CCCCHHHCCCCCCCC | 27.15 | 22369663 | |
| 2164 | Phosphorylation | YTDIISKSSTVKDAT CCHHHCCCCCCCCEE | 25.17 | 22369663 | |
| 2165 | Phosphorylation | TDIISKSSTVKDATI CHHHCCCCCCCCEEE | 40.74 | 20377248 | |
| 2166 | Phosphorylation | DIISKSSTVKDATIF HHHCCCCCCCCEEEE | 38.37 | 20377248 | |
| 2171 | Phosphorylation | SSTVKDATIFIPAYE CCCCCCEEEEEECHH | 26.93 | 22369663 | |
| 2177 | Phosphorylation | ATIFIPAYENIKNSA EEEEEECHHHHCCHH | 12.26 | 22369663 | |
| 2181 | Ubiquitination | IPAYENIKNSAEKLG EECHHHHCCHHHHHC | 57.33 | 22817900 | |
| 2183 | Phosphorylation | AYENIKNSAEKLGYK CHHHHCCHHHHHCCE | 32.57 | 28889911 | |
| 2186 | Ubiquitination | NIKNSAEKLGYKLVP HHCCHHHHHCCEEEE | 47.10 | 23749301 | |
| 2190 | Ubiquitination | SAEKLGYKLVPFEKS HHHHHCCEEEECCCC | 41.01 | 22817900 | |
| 2196 | Acetylation | YKLVPFEKSNINLKN CEEEECCCCCCCCCC | 49.54 | 24489116 | |
| 2196 | Ubiquitination | YKLVPFEKSNINLKN CEEEECCCCCCCCCC | 49.54 | 23749301 | |
| 2197 | Phosphorylation | KLVPFEKSNINLKNI EEEECCCCCCCCCCC | 35.43 | 17330950 | |
| 2202 | Ubiquitination | EKSNINLKNIEAPLF CCCCCCCCCCCCCCC | 51.93 | 24961812 | |
| 2210 | Phosphorylation | NIEAPLFSKDNDDTS CCCCCCCCCCCCCCC | 46.94 | 29136822 | |
| 2216 | Phosphorylation | FSKDNDDTSVASSID CCCCCCCCCCCHHCC | 28.15 | 22369663 | |
| 2217 | Phosphorylation | SKDNDDTSVASSIDL CCCCCCCCCCHHCCH | 23.76 | 22369663 | |
| 2220 | Phosphorylation | NDDTSVASSIDLDHL CCCCCCCHHCCHHHH | 26.18 | 22369663 | |
| 2221 | Phosphorylation | DDTSVASSIDLDHLS CCCCCCHHCCHHHHH | 15.47 | 22369663 | |
| 2228 | Phosphorylation | SIDLDHLSRKAEKYG HCCHHHHHHHHHHHC | 28.45 | 29136822 | |
| 2281 | Phosphorylation | LAAKTTNTAQEGAFQ CCHHCCCHHHCCCCC | 27.85 | 21551504 | |
| 2348 | Phosphorylation | MSQNEAVYGDDISDS CCCCCCHHCCCCCHH | 23.14 | 19779198 | |
| 2353 | Phosphorylation | AVYGDDISDSFVDES CHHCCCCCHHHCCHH | 33.91 | 20377248 | |
| 2355 | Phosphorylation | YGDDISDSFVDESQE HCCCCCHHHCCHHHH | 22.00 | 21440633 | |
| 2360 | Phosphorylation | SDSFVDESQEIKNDV CHHHCCHHHHHHCCH | 28.75 | 19795423 | |
| 2371 | Ubiquitination | KNDVDIIKTQAMKYG HCCHHHHHHHHHHHC | 34.61 | 23749301 | |
| 2407 | Phosphorylation | DIVVLSASYYHNLMS HEEEEEHHHHCCCCC | 23.89 | 28889911 | |
| 2424 | Phosphorylation | DMKWNCVSNEELQAE HCCCCCCCHHHHHHH | 40.50 | 27214570 | |
| 2462 | Acetylation | KHEYVSHKLNNKTST HHHHHHHHHCCCCCE | 45.46 | 25381059 | |
| 2466 | Ubiquitination | VSHKLNNKTSTVSTK HHHHHCCCCCEEECC | 42.66 | 23749301 | |
| 2467 | Phosphorylation | SHKLNNKTSTVSTKS HHHHCCCCCEEECCC | 31.58 | 19823750 | |
| 2468 | Phosphorylation | HKLNNKTSTVSTKSG HHHCCCCCEEECCCH | 28.55 | 17287358 | |
| 2469 | Phosphorylation | KLNNKTSTVSTKSGA HHCCCCCEEECCCHH | 24.57 | 17287358 | |
| 2471 | Phosphorylation | NNKTSTVSTKSGAKK CCCCCEEECCCHHHH | 30.15 | 17287358 | |
| 2472 | Phosphorylation | NKTSTVSTKSGAKKG CCCCEEECCCHHHHH | 25.54 | 19684113 | |
| 2474 | Phosphorylation | TSTVSTKSGAKKGLA CCEEECCCHHHHHHH | 44.03 | 19684113 | |
| 2486 | Phosphorylation | GLAEAAATTAYEDSE HHHHHHHHHCHHCCC | 13.77 | 19779198 | |
| 2487 | Phosphorylation | LAEAAATTAYEDSES HHHHHHHHCHHCCCC | 23.63 | 24961812 | |
| 2489 | Phosphorylation | EAAATTAYEDSESHP HHHHHHCHHCCCCCC | 20.41 | 28889911 | |
| 2492 | Phosphorylation | ATTAYEDSESHPQIE HHHCHHCCCCCCCHH | 29.11 | 28889911 | |
| 2494 | Phosphorylation | TAYEDSESHPQIEEQ HCHHCCCCCCCHHHH | 44.40 | 17330950 | |
| 2502 | Phosphorylation | HPQIEEQSHRTNHHK CCCHHHHHHHCCCHH | 20.44 | 28889911 | |
| 2505 | Phosphorylation | IEEQSHRTNHHKHHK HHHHHHHCCCHHHHH | 33.22 | 24961812 | |
| 2516 | Phosphorylation | KHHKRQQSLNSNSTS HHHHHHHHCCCCCCC | 22.60 | 17563356 | |
| 2519 | Phosphorylation | KRQQSLNSNSTSKTT HHHHHCCCCCCCCCC | 37.13 | 25521595 | |
| 2521 | Phosphorylation | QQSLNSNSTSKTTHS HHHCCCCCCCCCCCC | 33.60 | 28889911 | |
| 2522 | Phosphorylation | QSLNSNSTSKTTHSS HHCCCCCCCCCCCCC | 38.19 | 29734811 | |
| 2523 | Phosphorylation | SLNSNSTSKTTHSSR HCCCCCCCCCCCCCC | 28.03 | 19823750 | |
| 2542 | Phosphorylation | SRRDIVASFMSRAGS HHHHHHHHHHHHCCC | 15.58 | 24930733 | |
| 2545 | Phosphorylation | DIVASFMSRAGSASR HHHHHHHHHCCCHHC | 19.57 | 24930733 | |
| 2658 | Phosphorylation | SIVVTTETRTIKFTC EEEEECCCEEEEEEC | 30.90 | 28889911 | |
| 2690 | Phosphorylation | QRNMQGISLEDIADD HHHCCCCCHHHHCCC | 32.31 | 27214570 | |
| 2706 | Ubiquitination | TDNMYSGKIFPLPGE CCCCCCCCEECCCCC | 34.92 | 23749301 | |
| 2718 | Phosphorylation | PGENTKSSSKRLSAS CCCCCCCCHHHHCHH | 41.24 | 21440633 | |
| 2743 | Phosphorylation | HRVPQSRSFGNLR-- HCCCCCCCCCCCC-- | 42.63 | 24909858 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of NUM1_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of NUM1_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of NUM1_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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| Phosphorylation | |
| Reference | PubMed |
| "A multidimensional chromatography technology for in-depthphosphoproteome analysis."; Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.; Mol. Cell. Proteomics 7:1389-1396(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-62; SER-1329; SER-1331;SER-1464; THR-1466; SER-2078; SER-2197; SER-2220; SER-2221; SER-2353;SER-2407; SER-2468 AND SER-2519, AND MASS SPECTROMETRY. | |
| "Proteome-wide identification of in vivo targets of DNA damagecheckpoint kinases."; Smolka M.B., Albuquerque C.P., Chen S.H., Zhou H.; Proc. Natl. Acad. Sci. U.S.A. 104:10364-10369(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-2197; SER-2220;SER-2221; SER-2516 AND SER-2519, AND MASS SPECTROMETRY. | |
| "Analysis of phosphorylation sites on proteins from Saccharomycescerevisiae by electron transfer dissociation (ETD) massspectrometry."; Chi A., Huttenhower C., Geer L.Y., Coon J.J., Syka J.E.P., Bai D.L.,Shabanowitz J., Burke D.J., Troyanskaya O.G., Hunt D.F.; Proc. Natl. Acad. Sci. U.S.A. 104:2193-2198(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-2468; THR-2469 ANDSER-2471, AND MASS SPECTROMETRY. | |
| "Large-scale phosphorylation analysis of alpha-factor-arrestedSaccharomyces cerevisiae."; Li X., Gerber S.A., Rudner A.D., Beausoleil S.A., Haas W., Villen J.,Elias J.E., Gygi S.P.; J. Proteome Res. 6:1190-1197(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-2197, AND MASSSPECTROMETRY. | |
| "Quantitative phosphoproteomics applied to the yeast pheromonesignaling pathway."; Gruhler A., Olsen J.V., Mohammed S., Mortensen P., Faergeman N.J.,Mann M., Jensen O.N.; Mol. Cell. Proteomics 4:310-327(2005). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-2743, AND MASSSPECTROMETRY. | |
