COG2_YEAST - dbPTM
COG2_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID COG2_YEAST
UniProt AC P53271
Protein Name Conserved oligomeric Golgi complex subunit 2
Gene Name COG2
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 262
Subcellular Localization Golgi apparatus membrane
Peripheral membrane protein
Cytoplasmic side .
Protein Description Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events. COG2 is required for ER to Golgi vesicle docking. Not essential for viability..
Protein Sequence MDFLNDDELDLDLPVTAEISKELFATEIEKYRESETNGTDVDNFDVDRFLVQKNFHYLPLDSLIRDLSGLSQKMVQTLLEQIRSNYDDYLTFSNTYTDEENETLINLEKTQSDLQKFMTQLDHLIKDDISNTQEIIKDVLEYLKKLDEIYGSLRNHSQLTEALSLGKRLSKSLHEMCGIEPLEEEICSGLIEQLYKLITASRRILESCADSNSPYIHHLRNDYQDLLQEFQISLKILTEKCLENPSSLQNLSLTLVSIIKTA
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster

Oops, there are no PTM records of COG2_YEAST !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of COG2_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of COG2_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of COG2_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
COG8_YEASTCOG8physical
11703943
COG3_YEASTCOG3physical
12011112
SED5_YEASTSED5physical
12011112
COG1_YEASTCOG1physical
12006647
COG6_YEASTCOG6physical
12006647
COG4_YEASTCOG4physical
12006647
COG3_YEASTCOG3physical
11733049
COG1_YEASTCOG1physical
12011112
COG6_YEASTCOG6physical
12011112
COG4_YEASTCOG4physical
12011112
COG3_YEASTCOG3physical
10562277
COG4_YEASTCOG4physical
11733049
COPG_YEASTSEC21physical
12011112
COG1_YEASTCOG1physical
15932880
COG2_YEASTCOG2physical
15932880
COG3_YEASTCOG3physical
12006647
BET1_YEASTBET1genetic
9606204
RUD3_YEASTRUD3genetic
12646213
SEC22_YEASTSEC22genetic
9606204
COG3_YEASTCOG3genetic
10512869
COG3_YEASTCOG3genetic
11733049
SLY1_YEASTSLY1genetic
12006647
SLY1_YEASTSLY1genetic
9606204
COG1_YEASTCOG1genetic
12006647
YKT6_YEASTYKT6genetic
9606204
COG4_YEASTCOG4genetic
12006647
YPT1_YEASTYPT1genetic
9606204
COG5_YEASTCOG5genetic
12006647
COG8_YEASTCOG8genetic
12006647
COG6_YEASTCOG6genetic
12006647
RL8A_YEASTRPL8Agenetic
11733049
SSBP1_YEASTSBP1genetic
11733049
COG4_YEASTCOG4genetic
11733049
RGP1_YEASTRGP1genetic
16269340
NNF2_YEASTNNF2genetic
16269340
COG1_YEASTCOG1physical
18086915
COG3_YEASTCOG3physical
18086915
COG4_YEASTCOG4physical
18086915
COG5_YEASTCOG5physical
18086915
COG6_YEASTCOG6physical
18086915
COG7_YEASTCOG7physical
18086915
COG8_YEASTCOG8physical
18086915
ABM1_YEASTABM1physical
18467557
COG2_YEASTCOG2physical
18719252
ARL1_YEASTARL1genetic
20093466
GET3_YEASTGET3genetic
20093466
TRS85_YEASTTRS85genetic
20093466
ODO2_YEASTKGD2genetic
20093466
SSD1_YEASTSSD1genetic
20093466
VPS74_YEASTVPS74genetic
20093466
GET2_YEASTGET2genetic
20093466
PDK2_YEASTPKP2genetic
20093466
ERV14_YEASTERV14genetic
20093466
GET1_YEASTGET1genetic
20093466
COG7_YEASTCOG7genetic
20093466
OPI1_YEASTOPI1genetic
20093466
THIK_YEASTPOT1genetic
20093466
MTC1_YEASTMTC1genetic
20093466
SYS1_YEASTSYS1genetic
20093466
CYP7_YEASTCPR7genetic
20093466
CBF1_YEASTCBF1genetic
20093466
MOG1_YEASTMOG1genetic
20093466
FRMSR_YEASTYKL069Wgenetic
20093466
ELM1_YEASTELM1genetic
20093466
IRS4_YEASTIRS4genetic
20093466
VPS51_YEASTVPS51genetic
20093466
RIC1_YEASTRIC1genetic
20093466
ALAM_YEASTALT1genetic
20093466
YPT6_YEASTYPT6genetic
20093466
COG8_YEASTCOG8genetic
20093466
RCE1_YEASTRCE1genetic
20093466
COG5_YEASTCOG5genetic
20093466
COG6_YEASTCOG6genetic
20093466
TRM11_YEASTTRM11genetic
20093466
TLG2_YEASTTLG2genetic
20093466
GYP1_YEASTGYP1genetic
20093466
RUD3_YEASTRUD3genetic
20093466
ATG5_YEASTATG5genetic
20093466
ARL3_YEASTARL3genetic
20093466
NAA30_YEASTMAK3genetic
20093466
ATG12_YEASTATG12physical
20065092
ATG17_YEASTATG17physical
20065092
ATG20_YEASTATG20physical
20065092
SNX4_YEASTSNX4physical
20065092
COG3_YEASTCOG3physical
20972446
COG4_YEASTCOG4physical
20972446
COG1_YEASTCOG1physical
20972446
ITT1_YEASTITT1genetic
11733049
ELM1_YEASTELM1genetic
22282571
SEC23_YEASTSEC23genetic
27708008
ELM1_YEASTELM1genetic
27708008
EF1G2_YEASTTEF4genetic
27708008
RS10A_YEASTRPS10Agenetic
27708008
KAR3_YEASTKAR3genetic
27708008
SEC17_YEASTSEC17genetic
27708008
CDS1_YEASTCDS1genetic
27708008
SEC18_YEASTSEC18genetic
27708008
TRS20_YEASTTRS20genetic
27708008
CDC7_YEASTCDC7genetic
27708008
USO1_YEASTUSO1genetic
27708008
DPOD_YEASTPOL3genetic
27708008
RPB1_YEASTRPO21genetic
27708008
COPA_YEASTCOP1genetic
27708008
RRP1_YEASTRRP1genetic
27708008
CDC1_YEASTCDC1genetic
27708008
SLY1_YEASTSLY1genetic
27708008
COPB_YEASTSEC26genetic
27708008
TRS23_YEASTTRS23genetic
27708008
GPI11_YEASTGPI11genetic
27708008
GPI8_YEASTGPI8genetic
27708008
GPI19_YEASTGPI19genetic
27708008
COG3_YEASTCOG3genetic
27708008
MOB2_YEASTMOB2genetic
27708008
YPT1_YEASTYPT1genetic
27708008
SAD1_YEASTSAD1genetic
27708008
GPI16_YEASTGPI16genetic
27708008
GWT1_YEASTGWT1genetic
27708008
HSP77_YEASTSSC1genetic
27708008
YKT6_YEASTYKT6genetic
27708008
BET3_YEASTBET3genetic
27708008
SSL1_YEASTSSL1genetic
27708008
BOS1_YEASTBOS1genetic
27708008
SEC22_YEASTSEC22genetic
27708008
TAD3_YEASTTAD3genetic
27708008
SEN1_YEASTSEN1genetic
27708008
CDC91_YEASTGAB1genetic
27708008
ORC1_YEASTORC1genetic
27708008
BET5_YEASTBET5genetic
27708008
VTI1_YEASTVTI1genetic
27708008
RNA1_YEASTRNA1genetic
27708008
GPI12_YEASTGPI12genetic
27708008
CAP_YEASTSRV2genetic
27708008
GPI2_YEASTGPI2genetic
27708008
YAJ9_YEASTYAR029Wgenetic
27708008
SFT2_YEASTSFT2genetic
27708008
MUM2_YEASTMUM2genetic
27708008
ARL1_YEASTARL1genetic
27708008
THRC_YEASTTHR4genetic
27708008
BUD31_YEASTBUD31genetic
27708008
BRE1_YEASTBRE1genetic
27708008
VAM6_YEASTVAM6genetic
27708008
RL13A_YEASTRPL13Agenetic
27708008
GET3_YEASTGET3genetic
27708008
VPS41_YEASTVPS41genetic
27708008
TRS85_YEASTTRS85genetic
27708008
SAC3_YEASTSAC3genetic
27708008
ACL4_YEASTYDR161Wgenetic
27708008
UME6_YEASTUME6genetic
27708008
MNN10_YEASTMNN10genetic
27708008
SSF2_YEASTSSF2genetic
27708008
VPS74_YEASTVPS74genetic
27708008
RV167_YEASTRVS167genetic
27708008
GET2_YEASTGET2genetic
27708008
MSH4_YEASTMSH4genetic
27708008
WWM1_YEASTWWM1genetic
27708008
UBP6_YEASTUBP6genetic
27708008
ATC1_YEASTPMR1genetic
27708008
HUR1_YEASTHUR1genetic
27708008
VAM7_YEASTVAM7genetic
27708008
YGZ2_YEASTYGL242Cgenetic
27708008
SCW4_YEASTSCW4genetic
27708008
OPI1_YEASTOPI1genetic
27708008
GOSR1_YEASTGOS1genetic
27708008
HTD2_YEASTHTD2genetic
27708008
SNL1_YEASTSNL1genetic
27708008
SYS1_YEASTSYS1genetic
27708008
VPS53_YEASTVPS53genetic
27708008
YJE9_YEASTYJL049Wgenetic
27708008
GPI7_YEASTLAS21genetic
27708008
MTC1_YEASTMTC1genetic
27708008
SET2_YEASTSET2genetic
27708008
CYP7_YEASTCPR7genetic
27708008
LST4_YEASTLST4genetic
27708008
CASP_YEASTCOY1genetic
27708008
IRS4_YEASTIRS4genetic
27708008
VPS51_YEASTVPS51genetic
27708008
GMH1_YEASTGMH1genetic
27708008
NU133_YEASTNUP133genetic
27708008
UBI4P_YEASTUBI4genetic
27708008
RIC1_YEASTRIC1genetic
27708008
UPS1_YEASTUPS1genetic
27708008
ENT2_YEASTENT2genetic
27708008
ARV1_YEASTARV1genetic
27708008
YPT6_YEASTYPT6genetic
27708008
SPH1_YEASTSPH1genetic
27708008
COG8_YEASTCOG8genetic
27708008
RCO1_YEASTRCO1genetic
27708008
ERG2_YEASTERG2genetic
27708008
RCE1_YEASTRCE1genetic
27708008
GOT1_YEASTGOT1genetic
27708008
GAS1_YEASTGAS1genetic
27708008
COG6_YEASTCOG6genetic
27708008
COG5_YEASTCOG5genetic
27708008
ATG3_YEASTATG3genetic
27708008
TLG2_YEASTTLG2genetic
27708008
MSN1_YEASTMSN1genetic
27708008
SGT2_YEASTSGT2genetic
27708008
CSK2C_YEASTCKB2genetic
27708008
VAM10_YEASTVAM10genetic
27708008
GYP1_YEASTGYP1genetic
27708008
RUD3_YEASTRUD3genetic
27708008
PMT3_YEASTPMT3genetic
27708008
ARL3_YEASTARL3genetic
27708008
GGPPS_YEASTBTS1genetic
27708008
SYH1_YEASTSYH1genetic
27708008
HSP7F_YEASTSSE1genetic
27708008
BECN1_YEASTVPS30genetic
27708008
ATG5_YEASTATG5genetic
27708008
OYE3_YEASTOYE3genetic
27708008
COX10_YEASTCOX10genetic
27708008
RU2A_YEASTLEA1genetic
27708008
ATG41_YEASTICY2genetic
27708008
NAA30_YEASTMAK3genetic
27708008
CHMU_YEASTARO7genetic
27708008

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of COG2_YEAST

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Related Literatures of Post-Translational Modification

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