FRMSR_YEAST - dbPTM
FRMSR_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID FRMSR_YEAST
UniProt AC P36088
Protein Name Free methionine-R-sulfoxide reductase
Gene Name YKL069W
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 180
Subcellular Localization Cytoplasm . Nucleus .
Protein Description Catalyzes the reversible oxidation-reduction of the R-enantiomer of free methionine sulfoxide to methionine. Does not act on S-enantiomer of free methionine sulfoxide or R-enantiomer of dabsylated methionine sulfoxide. Involved in protection against oxidative stress..
Protein Sequence MGSSTGFHHADHVNYSSNLNKEEILEQLLLSYEGLSDGQVNWVCNLSNASSLIWHAYKSLAVDINWAGFYVTQASEENTLILGPFQGKVACQMIQFGKGVCGTAASTKETQIVPDVNKYPGHIACDGETKSEIVVPIISNDGKTLGVIDIDCLDYEGFDHVDKEFLEKLAKLINKSCVFK
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
3Phosphorylation-----MGSSTGFHHA
-----CCCCCCCCCC		24.3524961812
4Phosphorylation----MGSSTGFHHAD
----CCCCCCCCCCC		27.1624961812
5Phosphorylation---MGSSTGFHHADH
---CCCCCCCCCCCC		45.6324961812
98UbiquitinationCQMIQFGKGVCGTAA
HEEEECCCCCCCCCC		49.8423749301
118AcetylationQIVPDVNKYPGHIAC
EECCCHHHCCCCEEC		53.3124489116
129PhosphorylationHIACDGETKSEIVVP
CEECCCCCCCEEEEE		45.4524930733
175UbiquitinationKLAKLINKSCVFK--
HHHHHHHHHCCCC--		37.9323749301
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of FRMSR_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of FRMSR_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of FRMSR_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
GPP2_YEASTGPP2physical
16554755
CLC1_YEASTCLC1physical
16554755
MON1_YEASTMON1genetic
17314980
MED31_YEASTSOH1genetic
17314980
LRP1_YEASTLRP1genetic
17314980
HIR1_YEASTHIR1genetic
17314980
SA155_YEASTSAP155genetic
17314980
SAC3_YEASTSAC3genetic
17314980
PEX22_YEASTPEX22genetic
17314980
TRX2_YEASTTRX2physical
18719252
FRMSR_YEASTYKL069Wphysical
18719252
TRX2_YEASTTRX2physical
27816612
MOB2_YEASTMOB2genetic
27708008
YAJ9_YEASTYAR029Wgenetic
27708008
GPX2_YEASTGPX2genetic
27708008
SHG1_YEASTSHG1genetic
27708008
CHK1_YEASTCHK1genetic
27708008
ATU1_YEASTPCA1genetic
27708008
TPS2_YEASTTPS2genetic
27708008
RPA14_YEASTRPA14genetic
27708008
PDR15_YEASTPDR15genetic
27708008
MET10_YEASTMET10genetic
27708008
SA155_YEASTSAP155genetic
27708008
CGR1_YEASTCGR1genetic
27708008
BUB1_YEASTBUB1genetic
27708008
DOG1_YEASTDOG1genetic
27708008
TAX4_YEASTTAX4genetic
27708008
PHO86_YEASTPHO86genetic
27708008
BPT1_YEASTBPT1genetic
27708008
AYT1_YEASTAYT1genetic
27708008
CCW12_YEASTCCW12genetic
27708008
ARV1_YEASTARV1genetic
27708008
PMA2_YEASTPMA2genetic
27708008
KAR3_YEASTKAR3genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of FRMSR_YEAST

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Related Literatures of Post-Translational Modification

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