TAX4_YEAST - dbPTM
TAX4_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID TAX4_YEAST
UniProt AC P47030
Protein Name Protein TAX4
Gene Name TAX4
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 604
Subcellular Localization
Protein Description With IRS4, acts as a positive regulator of INP51 activity and phosphatidylinositol 4,5-bisphosphate turnover. Negatively regulates signaling through the cell integrity pathway, including the MAP kinase SLT2..
Protein Sequence MHFPKKKHSGNLSVVELPKEALQDSLTAAQITFKRYAHPNGNAGSAERPRHLKVESAPVVKSEPSLPRMRQPEPRSINHQYSRETLPGHSEAFSVPTTPLQTIHYDVRNKASNSPSSIAAAETAAYLAHTNSFSNRSSGVGSRDPVMDTETKPPRAPSALKNELQLNRMRIPPPSYDNNVRSRSISPQVSYSTSLSSSCSISSDGEETSYREKSTDEAFPPEPSMSSYSLASKASAKASLTDPSQRQQESDYTAMNKLNGGNIIYKGTLPDLIPRSQRKTSKPRFKHRLLRSPEQQQENLSRVYSDQTQNGRAIINTQQNVKLKTTMRRGKYAITDNDETFPYDRKSVSSDSDTDEDSNVMEIKDKKKKSRRSKIKKGLKTTAAVVGSSTSVLPFPHHHHHHHQLHNPNSHHLHTHHHTSSHKFNEDKPWKSHRDLGFITEQERKRYESMWVSNRYSYLRLLPWWPSLANEDDESHLQPLNLPQDGLMLNLVVKDIWYRSNLPRDLLVQIYNMVDTRKDGTLDRKSFIVGMWLVDQCLYGRKLTNELDQRVWNSVDGYVLGTINVKPATSDHYHNANNPLDKPSKLSVRQELKNIKRDLRNVRI
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
9PhosphorylationHFPKKKHSGNLSVVE
CCCCCCCCCCCCEEE		37.9519779198
13PhosphorylationKKHSGNLSVVELPKE
CCCCCCCCEEECCHH		28.2822369663
36PhosphorylationAQITFKRYAHPNGNA
HHHHHHHCCCCCCCC		15.1727017623
45PhosphorylationHPNGNAGSAERPRHL
CCCCCCCCCCCCCCC		25.2527017623
56PhosphorylationPRHLKVESAPVVKSE
CCCCEECCCCCCCCC		40.6422369663
85PhosphorylationNHQYSRETLPGHSEA
CCCCCCCCCCCCCCC		36.8222369663
90PhosphorylationRETLPGHSEAFSVPT
CCCCCCCCCCCCCCC		36.2122369663
94PhosphorylationPGHSEAFSVPTTPLQ
CCCCCCCCCCCCCCC		33.9522369663
97PhosphorylationSEAFSVPTTPLQTIH
CCCCCCCCCCCCEEE		38.6022369663
98PhosphorylationEAFSVPTTPLQTIHY
CCCCCCCCCCCEEEC		18.8722369663
102PhosphorylationVPTTPLQTIHYDVRN
CCCCCCCEEECCCCC		19.8722369663
105PhosphorylationTPLQTIHYDVRNKAS
CCCCEEECCCCCCCC		16.5722369663
112PhosphorylationYDVRNKASNSPSSIA
CCCCCCCCCCHHHHH		39.1822369663
114PhosphorylationVRNKASNSPSSIAAA
CCCCCCCCHHHHHHH		24.5422369663
116PhosphorylationNKASNSPSSIAAAET
CCCCCCHHHHHHHHH		33.9122369663
117PhosphorylationKASNSPSSIAAAETA
CCCCCHHHHHHHHHH		21.4522369663
158PhosphorylationTKPPRAPSALKNELQ
CCCCCCCHHHHHHHH		45.2919779198
214PhosphorylationETSYREKSTDEAFPP
CCCCCCCCCCCCCCC		36.0229688323
215PhosphorylationTSYREKSTDEAFPPE
CCCCCCCCCCCCCCC		49.2629688323
227PhosphorylationPPEPSMSSYSLASKA
CCCCCCCHHHHHHHH		15.3129688323
228PhosphorylationPEPSMSSYSLASKAS
CCCCCCHHHHHHHHH		10.6129688323
229PhosphorylationEPSMSSYSLASKASA
CCCCCHHHHHHHHHH		21.2929688323
232PhosphorylationMSSYSLASKASAKAS
CCHHHHHHHHHHHHH		33.7629688323
265PhosphorylationLNGGNIIYKGTLPDL
HCCCCEEEECCCCCC		10.2827214570
292PhosphorylationFKHRLLRSPEQQQEN
HHHHHHCCHHHHHHH		32.5328889911
305PhosphorylationENLSRVYSDQTQNGR
HHHHHHCCCCCCCCC		22.0128889911
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of TAX4_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of TAX4_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of TAX4_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
LSP1_YEASTLSP1physical
18719252
MTL1_YEASTMTL1genetic
27708008
ANS1_YEASTANS1genetic
27708008
CAF4_YEASTCAF4genetic
27708008
YGK8_YEASTYGL108Cgenetic
27708008
MED5_YEASTNUT1genetic
27708008
YRB30_YEASTYRB30genetic
27708008
XRN1_YEASTXRN1genetic
27708008
DSD1_YEASTDSD1genetic
27708008
THI4_YEASTTHI4genetic
27708008
AP3B_YEASTAPL6genetic
27708008
SHU1_YEASTSHU1genetic
27708008
TOM71_YEASTTOM71genetic
27708008
KEL1_YEASTKEL1genetic
27708008
PTH_YEASTPTH1genetic
27708008
YIA6_YEASTYIA6genetic
27708008
RL16A_YEASTRPL16Agenetic
27708008
ALLA_YEASTDAL3genetic
27708008
RL43A_YEASTRPL43Bgenetic
27708008
RL43B_YEASTRPL43Bgenetic
27708008
EFM3_YEASTEFM3genetic
27708008
HCS1_YEASTHCS1genetic
27708008
UTH1_YEASTUTH1genetic
27708008
RL40A_YEASTRPL40Bgenetic
27708008
RL40B_YEASTRPL40Bgenetic
27708008
LAM6_YEASTYLR072Wgenetic
27708008
SWI6_YEASTSWI6genetic
27708008
UPS1_YEASTUPS1genetic
27708008
ROM2_YEASTROM2genetic
27708008
VPS9_YEASTVPS9genetic
27708008
MSC1_YEASTMSC1genetic
27708008
JLP2_YEASTJLP2genetic
27708008
MLH1_YEASTMLH1genetic
27708008
MAS5_YEASTYDJ1genetic
27708008
RNH2A_YEASTRNH201genetic
27708008
MKS1_YEASTMKS1genetic
27708008
LSM7_YEASTLSM7genetic
27708008
BRE5_YEASTBRE5genetic
27708008
BRR1_YEASTBRR1genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of TAX4_YEAST

loading...

Related Literatures of Post-Translational Modification

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory