| UniProt ID | EFM3_YEAST | |
|---|---|---|
| UniProt AC | P47163 | |
| Protein Name | Protein-lysine N-methyltransferase EFM3 {ECO:0000305|PubMed:25086354} | |
| Gene Name | EFM3 {ECO:0000303|PubMed:25086354} | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 339 | |
| Subcellular Localization | Cytoplasm . | |
| Protein Description | S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that mono-, di- and trimethylates elongation factor 2 (EFT1/EFT2) at 'Lys-509'.. | |
| Protein Sequence | MNEDLFYDRLHQRCPGKYLLEELETSKSNDVLHASRFVCEMELVQKTNAYYCKTIVKMLLDHEWIFAKAFTIVNDGEDEIEIYDYLYEKYIKLLSTGKPDPMMKDVVRYRFDEDVKIKIEETPNLISAASTTGFRTWEAALYMGDFLIHKPLQELAPVQGQDDGKKKLNVLEVGAGTGIVSLVILQKYHEFVNKMYVTDGDSNLVETQLKRNFELNNEVRENEPDIKLQRLWWGSDRVPEDIDLVVGADVTYDPTILPDLCECLAECLALDRCKLCLLSATIRSESTVQLFSQECNKLGLKCTIVTSTEYDANNEIRAMKALQFKPLIAPIRIYKITKQ | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 177 | Phosphorylation | VLEVGAGTGIVSLVI EEEECCCCCHHHHHH | 28889911 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of EFM3_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of EFM3_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of EFM3_YEAST !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| EFM2_YEAST | EFM2 | genetic | 25086354 | |
| EF2_YEAST | EFT2 | physical | 25231979 | |
| EF2_HUMAN | EEF2 | physical | 25231979 | |
| ETR1_YEAST | ETR1 | genetic | 27708008 | |
| CLPX_YEAST | MCX1 | genetic | 27708008 | |
| CSM1_YEAST | CSM1 | genetic | 27708008 | |
| UBP5_YEAST | UBP5 | genetic | 27708008 | |
| IES1_YEAST | IES1 | genetic | 27708008 | |
| DLDH_YEAST | LPD1 | genetic | 27708008 | |
| HTD2_YEAST | HTD2 | genetic | 27708008 | |
| ELM1_YEAST | ELM1 | genetic | 27708008 | |
| LIPA_YEAST | LIP5 | genetic | 27708008 | |
| VPH1_YEAST | VPH1 | genetic | 27708008 | |
| SUR1_YEAST | SUR1 | genetic | 27708008 | |
| HSP7F_YEAST | SSE1 | genetic | 27708008 | |
| TGS1_YEAST | TGS1 | genetic | 27708008 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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