IES1_YEAST - dbPTM
IES1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID IES1_YEAST
UniProt AC P43579
Protein Name Ino eighty subunit 1
Gene Name IES1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 692
Subcellular Localization Nucleus .
Protein Description Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin-remodeling complex..
Protein Sequence MGKRVYDPIHDTFQLREDNSDETKADSPMQSVKSGSQEEASPSSIQSETETVTTKSIPVIHEIEIDDKNDDDSTQSEEENTNILLNFEPSTVPEATGASTATGPVTTNTVRRKPKESNASKYNRHLKKPDGEPFNRKDIQFSFMQELLMDKRQIFTNVLKPLYKNSIVPINIDGDKLSINVTDKEYDARTFVFNDKLTFAQLYVLTIATSIKCSKILRDKLLLDQQVAFSTCVLALLVNIGRLNTTINFYLEMTSQLRTFHSVPVLQLHANDPKLLQDTPRLKSILKNLPWGNEQLSLMETYKKVDQNDGEVDTVNKFNIINMLFSICDNSGLIDKRFLSKYVEVESKAQEQDMVDEQNEVKETEAENEKQESKAAYATTLFDILDYSKYEPKDRSNILIWLLYIHLETNLSQEEVEESVRFFNGLEDGAPAGKFILRCTERSYDTDPEDELEFGANQRIKRREFMSKMEEGRKRERTNVTEVKKPSIGGDKSEEDGEGEDDKSEETVEETRSLLTPTPILESSSPMTLNRKKVTPQLPKVTPAAPTETEEEITSAAIIDKNDLNLTPLKKYNSSATVNKVDKLISLDLNKHVSENGKTQEEFLADLKKSQVPNRLKRRDIGLIKIFNEFEDIPVASVLGIRGKKRKKFKDNLLGFETDFMKNLGASKKVLLNKIERAEIDDEEATAMFKLE
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
20PhosphorylationFQLREDNSDETKADS
EECCCCCCCCCCCCC		49.5022369663
23PhosphorylationREDNSDETKADSPMQ
CCCCCCCCCCCCCCC		36.2022369663
27PhosphorylationSDETKADSPMQSVKS
CCCCCCCCCCCCCCC		27.4222369663
31PhosphorylationKADSPMQSVKSGSQE
CCCCCCCCCCCCCCC		25.8422369663
34PhosphorylationSPMQSVKSGSQEEAS
CCCCCCCCCCCCCCC		41.3322369663
36PhosphorylationMQSVKSGSQEEASPS
CCCCCCCCCCCCCCC		41.3222369663
41PhosphorylationSGSQEEASPSSIQSE
CCCCCCCCCCCCCCC		28.7020377248
43PhosphorylationSQEEASPSSIQSETE
CCCCCCCCCCCCCCE		37.2620377248
44PhosphorylationQEEASPSSIQSETET
CCCCCCCCCCCCCEE		28.2120377248
47PhosphorylationASPSSIQSETETVTT
CCCCCCCCCCEEEEC		44.8320377248
49PhosphorylationPSSIQSETETVTTKS
CCCCCCCCEEEECCC		42.0522369663
51PhosphorylationSIQSETETVTTKSIP
CCCCCCEEEECCCCC		30.4920377248
53PhosphorylationQSETETVTTKSIPVI
CCCCEEEECCCCCEE		35.6122369663
54PhosphorylationSETETVTTKSIPVIH
CCCEEEECCCCCEEE		20.6122369663
443PhosphorylationILRCTERSYDTDPED
EEEECCCCCCCCCHH		22.5622369663
444PhosphorylationLRCTERSYDTDPEDE
EEECCCCCCCCCHHH		29.1422369663
446PhosphorylationCTERSYDTDPEDELE
ECCCCCCCCCHHHCC		45.2622369663
481PhosphorylationKRERTNVTEVKKPSI
CCCCCCCCEECCCCC		36.8129136822
487PhosphorylationVTEVKKPSIGGDKSE
CCEECCCCCCCCCCC		42.6217330950
493PhosphorylationPSIGGDKSEEDGEGE
CCCCCCCCCCCCCCC		51.4617330950
504PhosphorylationGEGEDDKSEETVEET
CCCCCCCCCHHHHHH		47.8917330950
507PhosphorylationEDDKSEETVEETRSL
CCCCCCHHHHHHHHH		29.2117563356
511PhosphorylationSEETVEETRSLLTPT
CCHHHHHHHHHCCCC		16.4419795423
513PhosphorylationETVEETRSLLTPTPI
HHHHHHHHHCCCCCC		34.8422369663
516PhosphorylationEETRSLLTPTPILES
HHHHHHCCCCCCCCC		30.3422369663
518PhosphorylationTRSLLTPTPILESSS
HHHHCCCCCCCCCCC		20.0922369663
523PhosphorylationTPTPILESSSPMTLN
CCCCCCCCCCCCCCC		32.4423749301
524PhosphorylationPTPILESSSPMTLNR
CCCCCCCCCCCCCCC		29.1422369663
525PhosphorylationTPILESSSPMTLNRK
CCCCCCCCCCCCCCC		28.1522369663
528PhosphorylationLESSSPMTLNRKKVT
CCCCCCCCCCCCCCC		25.0222369663
535PhosphorylationTLNRKKVTPQLPKVT
CCCCCCCCCCCCCCC		17.7522369663
547PhosphorylationKVTPAAPTETEEEIT
CCCCCCCCCCHHHHH		51.3024961812
549PhosphorylationTPAAPTETEEEITSA
CCCCCCCCHHHHHHH		51.6924961812
554PhosphorylationTETEEEITSAAIIDK
CCCHHHHHHHEEECC		18.6524961812
555PhosphorylationETEEEITSAAIIDKN
CCHHHHHHHEEECCC		22.7424961812
567PhosphorylationDKNDLNLTPLKKYNS
CCCCCCCCCCCCCCC		26.0422369663
571AcetylationLNLTPLKKYNSSATV
CCCCCCCCCCCCCCC		58.3025381059
572PhosphorylationNLTPLKKYNSSATVN
CCCCCCCCCCCCCCC		20.7721440633
574PhosphorylationTPLKKYNSSATVNKV
CCCCCCCCCCCCCCC		20.4721440633
575PhosphorylationPLKKYNSSATVNKVD
CCCCCCCCCCCCCCC		25.0725752575
577PhosphorylationKKYNSSATVNKVDKL
CCCCCCCCCCCCCHH		26.9321440633
580AcetylationNSSATVNKVDKLISL
CCCCCCCCCCHHHHC		47.6922865919
583AcetylationATVNKVDKLISLDLN
CCCCCCCHHHHCCCH		51.1924489116
674AcetylationSKKVLLNKIERAEID
CHHHHHHHHHHHCCC		46.0124489116
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of IES1_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of IES1_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of IES1_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
H2A2_YEASTHTA2physical
16554755
SRO77_YEASTSRO77physical
16554755
RUVB1_YEASTRVB1physical
16554755
IF5A1_YEASTHYP2physical
16554755
INO80_YEASTINO80physical
16554755
ZUO1_YEASTZUO1physical
16554755
SSZ1_YEASTSSZ1physical
16554755
ARP4_YEASTARP4physical
16554755
EF1G2_YEASTTEF4physical
16554755
IES3_YEASTIES3physical
16554755
EF3A_YEASTYEF3physical
16554755
IES2_YEASTIES2physical
16554755
ARP8_YEASTARP8physical
16554755
IES4_YEASTIES4physical
16554755
EF1G1_YEASTCAM1physical
16554755
RUVB2_YEASTRVB2physical
16554755
ACT_YEASTACT1physical
16429126
INO80_YEASTINO80physical
16429126
NHP10_YEASTNHP10physical
16429126
RUVB1_YEASTRVB1physical
16429126
RUVB2_YEASTRVB2physical
16429126
ARP8_YEASTARP8physical
16429126
ARO1_YEASTARO1genetic
17314980
UME6_YEASTUME6genetic
17314980
GET2_YEASTGET2genetic
17314980
SSD1_YEASTSSD1genetic
17314980
SSN2_YEASTSSN2genetic
17314980
RSC6_YEASTRSC6genetic
17314980
RPN6_YEASTRPN6genetic
17314980
SWD1_YEASTSWD1genetic
17314980
NHP10_YEASTNHP10genetic
17314980
RAD50_YEASTRAD50genetic
15607974
RAD51_YEASTRAD51genetic
15607974
RAD54_YEASTRAD54genetic
15607974
RAD55_YEASTRAD55genetic
15607974
SSB1_YEASTSSB1physical
19536198
INO80_YEASTINO80physical
20190278
IES1_YEASTIES1physical
20190278
IES4_YEASTIES4physical
20190278
BDF1_YEASTBDF1physical
20190278
RFA1_YEASTRFA1physical
20190278
LEO1_YEASTLEO1physical
20190278
MSH6_YEASTMSH6physical
20190278
H2A1_YEASTHTA1physical
20190278
PRP19_YEASTPRP19physical
20190278
DPB4_YEASTDPB4physical
20190278
IWS1_YEASTSPN1physical
20190278
YPT6_YEASTYPT6genetic
20959818
HIR2_YEASTHIR2genetic
20959818
CTK1_YEASTCTK1genetic
20959818
UBP3_YEASTUBP3genetic
20959818
H3_YEASTHHT1physical
24034245
NHP10_YEASTNHP10genetic
27708008
CEM1_YEASTCEM1genetic
27708008
FRMSR_YEASTYKL069Wgenetic
27708008
LIPB_YEASTLIP2genetic
27708008
GID8_YEASTGID8genetic
27708008
RTG1_YEASTRTG1genetic
27708008
YOR31_YEASTYOR131Cgenetic
27708008
GGPPS_YEASTBTS1genetic
27708008
UBA3_YEASTUBA3genetic
27708008
DPOA2_YEASTPOL12genetic
27708008
DPOD_YEASTPOL3genetic
27708008
KIN28_YEASTKIN28genetic
27708008
CDC53_YEASTCDC53genetic
27708008
TCPD_YEASTCCT4genetic
27708008
RPC10_YEASTRPC11genetic
27708008
TCPZ_YEASTCCT6genetic
27708008
TFB1_YEASTTFB1genetic
27708008
RMRP_YEASTSNM1genetic
27708008
RSP5_YEASTRSP5genetic
27708008
STT3_YEASTSTT3genetic
27708008
PRI1_YEASTPRI1genetic
27708008
GRP78_YEASTKAR2genetic
27708008
PSF2_YEASTPSF2genetic
27708008
ARP4_YEASTARP4genetic
27708008
SSL1_YEASTSSL1genetic
27708008
SMC4_YEASTSMC4genetic
27708008
POB3_YEASTPOB3genetic
27708008
RPB2_YEASTRPB2genetic
27708008
APC5_YEASTAPC5genetic
27708008
RPA1_YEASTRPA190genetic
27708008
IWS1_YEASTSPN1genetic
27708008
PGTB2_YEASTBET2genetic
27708008
AVT5_YEASTAVT5genetic
27708008
PEX32_YEASTPEX32genetic
27708008
HPC2_YEASTHPC2genetic
27708008
STE50_YEASTSTE50genetic
27708008
MTU1_YEASTSLM3genetic
27708008
RS16A_YEASTRPS16Bgenetic
27708008
RS16B_YEASTRPS16Bgenetic
27708008
RGT2_YEASTRGT2genetic
27708008
DPB4_YEASTDPB4genetic
27708008
ARO1_YEASTARO1genetic
27708008
DHSD_YEASTSDH4genetic
27708008
RV167_YEASTRVS167genetic
27708008
LCMT1_YEASTPPM1genetic
27708008
YEY6_YEASTYER156Cgenetic
27708008
GUP1_YEASTGUP1genetic
27708008
ITC1_YEASTITC1genetic
27708008
AROC_YEASTARO2genetic
27708008
GCN1_YEASTGCN1genetic
27708008
DSD1_YEASTDSD1genetic
27708008
HXKB_YEASTHXK2genetic
27708008
CHO2_YEASTCHO2genetic
27708008
GTR2_YEASTGTR2genetic
27708008
BUB1_YEASTBUB1genetic
27708008
LRP1_YEASTLRP1genetic
27708008
WSS1_YEASTWSS1genetic
27708008
RPA34_YEASTRPA34genetic
27708008
YJY1_YEASTYJR011Cgenetic
27708008
RL14A_YEASTRPL14Agenetic
27708008
PIR1_YEASTPIR1genetic
27708008
DBP7_YEASTDBP7genetic
27708008
UTH1_YEASTUTH1genetic
27708008
RT109_YEASTRTT109genetic
27708008
BPT1_YEASTBPT1genetic
27708008
SDHB_YEASTSDH2genetic
27708008
BRE2_YEASTBRE2genetic
27708008
RAD5_YEASTRAD5genetic
27708008
SWI6_YEASTSWI6genetic
27708008
ADY4_YEASTADY4genetic
27708008
VRP1_YEASTVRP1genetic
27708008
RL26A_YEASTRPL26Agenetic
27708008
PALI_YEASTRIM9genetic
27708008
RIM13_YEASTRIM13genetic
27708008
HDA1_YEASTHDA1genetic
27708008
SIW14_YEASTSIW14genetic
27708008
TPM1_YEASTTPM1genetic
27708008
NST1_YEASTNST1genetic
27708008
AF9_YEASTYAF9genetic
27708008
MSO1_YEASTMSO1genetic
27708008
IZH2_YEASTIZH2genetic
27708008
SIN3_YEASTSIN3genetic
27708008
MET22_YEASTMET22genetic
27708008
RRP6_YEASTRRP6genetic
27708008
BUB3_YEASTBUB3genetic
27708008
HIR2_YEASTHIR2genetic
27708008
SYC1_YEASTSYC1genetic
27708008
IES4_YEASTIES4genetic
27708008
PALA_YEASTRIM20genetic
27708008
ISW2_YEASTISW2genetic
27708008
CHL1_YEASTCHL1genetic
27708008
MRX11_YEASTYPL041Cgenetic
27708008
ALDH6_YEASTALD6genetic
27708008
ELP4_YEASTELP4genetic
27708008
KA120_YEASTKAP120genetic
27708008
BRR1_YEASTBRR1genetic
27708008
MED1_YEASTMED1genetic
27708008
YP091_YEASTNVJ2genetic
27708008
HDA3_YEASTHDA3genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of IES1_YEAST

loading...

Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"A multidimensional chromatography technology for in-depthphosphoproteome analysis.";
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.;
Mol. Cell. Proteomics 7:1389-1396(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-34; SER-36; SER-47;SER-443; THR-446; THR-516; THR-567 AND SER-574, AND MASS SPECTROMETRY.
"Proteome-wide identification of in vivo targets of DNA damagecheckpoint kinases.";
Smolka M.B., Albuquerque C.P., Chen S.H., Zhou H.;
Proc. Natl. Acad. Sci. U.S.A. 104:10364-10369(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-27; SER-493; SER-504 ANDTHR-507, AND MASS SPECTROMETRY.

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory