GTR2_YEAST - dbPTM
GTR2_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID GTR2_YEAST
UniProt AC P53290
Protein Name GTP-binding protein GTR2
Gene Name GTR2
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 341
Subcellular Localization Vacuole membrane .
Protein Description GTPase. Component of the GSE complex, a GTPase complex required for intracellular sorting of GAP1 out of the endosome. Component of the EGO complex, a complex involved in the regulation of microautophagy..
Protein Sequence MSLEATDSKAMVLLMGVRRCGKSSICKVVFHNMQPLDTLYLESTSNPSLEHFSTLIDLAVMELPGQLNYFEPSYDSERLFKSVGALVYVIDSQDEYINAITNLAMIIEYAYKVNPSINIEVLIHKVDGLSEDFKVDAQRDIMQRTGEELLELGLDGVQVSFYLTSIFDHSIYEAFSRIVQKLIPELSFLENMLDNLIQHSKIEKAFLFDVNSKIYVSTDSNPVDIQMYEVCSEFIDVTIDLFDLYKAPVLRNSQKSSDKDNVINPRNELQNVSQLANGVIIYLRQMIRGLALVAIIRPNGTDMESCLTVADYNIDIFKKGLEDIWANARASQAKNSIEDDV
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
134UbiquitinationDGLSEDFKVDAQRDI
CCCCCCCCHHHHHHH
52.0724961812
204UbiquitinationIQHSKIEKAFLFDVN
HHCCCCCEEEEEECC
48.1624961812
253PhosphorylationKAPVLRNSQKSSDKD
CCHHCCCCCCCCCCC
32.3319823750
259UbiquitinationNSQKSSDKDNVINPR
CCCCCCCCCCCCCCH
53.8223749301
282PhosphorylationLANGVIIYLRQMIRG
HHHHHHHHHHHHHHH
5.6826447709
331PhosphorylationIWANARASQAKNSIE
HHHHHHHHHHHHHCC
25.7221440633
334UbiquitinationNARASQAKNSIEDDV
HHHHHHHHHHCCCCC
43.5223749301

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of GTR2_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of GTR2_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of GTR2_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
AMN1_YEASTAMN1physical
11805826
ESP1_YEASTESP1physical
11805826
RUVB2_YEASTRVB2physical
11805826
SPT16_YEASTSPT16physical
11805826
YCQ5_YEASTYCR015Cphysical
11805826
YCH1_YEASTYCH1physical
11805826
GTR1_YEASTGTR1physical
16732272
GTR2_YEASTGTR2physical
16732272
GAP1_YEASTGAP1physical
16732272
GTR1_YEASTGTR1physical
16143306
RTG1_YEASTRTG1genetic
15989961
RTG2_YEASTRTG2genetic
15989961
MEH1_YEASTMEH1physical
18467557
COT1_YEASTCOT1physical
18467557
MEH1_YEASTMEH1physical
19374031
GTR1_YEASTGTR1physical
19374031
INO80_YEASTINO80genetic
18258182
RUVB1_YEASTRVB1physical
18258182
RUVB2_YEASTRVB2physical
18258182
YCQ5_YEASTYCR015Cphysical
18258182
YCH1_YEASTYCH1physical
18258182
TOR1_YEASTTOR1genetic
15989961
IF4B_YEASTTIF3genetic
15989961
RTG3_YEASTRTG3genetic
15989961
MEH1_YEASTMEH1physical
22615397
PEP3_YEASTPEP3genetic
24514902
PEP5_YEASTPEP5genetic
24514902
GTR1_YEASTGTR1physical
24702707
GTR1_YEASTGTR1genetic
24702707
SLM4_YEASTSLM4physical
24702707
MEH1_YEASTMEH1physical
24702707
PDC2_YEASTPDC2genetic
27708008
RU1C_YEASTYHC1genetic
27708008
ECM8_YEASTECM8genetic
27708008
SLX5_YEASTSLX5genetic
27708008
LSM6_YEASTLSM6genetic
27708008
ICE2_YEASTICE2genetic
27708008
GTR1_YEASTGTR1genetic
27708008
ALG14_YEASTALG14genetic
27708008
CDC1_YEASTCDC1genetic
27708008
COG3_YEASTCOG3genetic
27708008
ACT_YEASTACT1genetic
27708008
PMM_YEASTSEC53genetic
27708008
BRL1_YEASTBRL1genetic
27708008
KOG1_YEASTKOG1genetic
27708008
ATC7_YEASTNEO1genetic
27708008
KTHY_YEASTCDC8genetic
27708008
BOS1_YEASTBOS1genetic
27708008
TAF11_YEASTTAF11genetic
27708008
LST8_YEASTLST8genetic
27708008
MED4_YEASTMED4genetic
27708008
MOT1_YEASTMOT1genetic
27708008
PSB5_YEASTPRE2genetic
27708008
PIN4_YEASTPIN4genetic
27708008
GAL7_YEASTGAL7genetic
27708008
MCFS2_YEASTEHT1genetic
27708008
PYC2_YEASTPYC2genetic
27708008
CLPX_YEASTMCX1genetic
27708008
CHK1_YEASTCHK1genetic
27708008
THRC_YEASTTHR4genetic
27708008
RLA1_YEASTRPP1Agenetic
27708008
CYK3_YEASTCYK3genetic
27708008
VMS1_YEASTVMS1genetic
27708008
NUM1_YEASTNUM1genetic
27708008
DHAS_YEASTHOM2genetic
27708008
GNTK_YEASTYDR248Cgenetic
27708008
IPK1_YEASTIPK1genetic
27708008
STP1_YEASTSTP1genetic
27708008
AK_YEASTHOM3genetic
27708008
METE_YEASTMET6genetic
27708008
PHO4_YEASTPHO4genetic
27708008
CNN1_YEASTCNN1genetic
27708008
RTG2_YEASTRTG2genetic
27708008
GOSR1_YEASTGOS1genetic
27708008
FMO1_YEASTFMO1genetic
27708008
VPS53_YEASTVPS53genetic
27708008
TOR1_YEASTTOR1genetic
27708008
DHOM_YEASTHOM6genetic
27708008
SAC1_YEASTSAC1genetic
27708008
POC3_YEASTIRC25genetic
27708008
UBR2_YEASTUBR2genetic
27708008
YL031_YEASTYLR031Wgenetic
27708008
LAM6_YEASTYLR072Wgenetic
27708008
FMP25_YEASTFMP25genetic
27708008
CCW12_YEASTCCW12genetic
27708008
EIF3J_YEASTHCR1genetic
27708008
RS22B_YEASTRPS22Bgenetic
27708008
CTK3_YEASTCTK3genetic
27708008
RT17_YEASTMRPS17genetic
27708008
SOL1_YEASTSOL1genetic
27708008
BRE5_YEASTBRE5genetic
27708008
RTG1_YEASTRTG1genetic
27708008
YO105_YEASTYOR105Wgenetic
27708008
SERC_YEASTSER1genetic
27708008
MRS2_YEASTMRS2genetic
27708008
YP084_YEASTYPR084Wgenetic
27708008
TOR1_YEASTTOR1genetic
27811238
YN034_YEASTYNR034W-Agenetic
26206314
YC075_YEASTYCR075W-Agenetic
26206314
IVY1_YEASTIVY1physical
25999476

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of GTR2_YEAST

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Related Literatures of Post-Translational Modification

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